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The map label for this gene is infC [H]

Identifier: 119945878

GI number: 119945878

Start: 2699961

End: 2700509

Strand: Reverse

Name: infC [H]

Synonym: Ping_2218

Alternate gene names: 119945878

Gene position: 2700509-2699961 (Counterclockwise)

Preceding gene: 119945879

Following gene: 119945877

Centisome position: 59.23

GC content: 41.71

Gene sequence:

>549_bases
TTGGTTATAAAAGGTGCAAAAAAAGCCCCACAACAGGGCAATAAACATCGTTTGAATGATGAGATCACCGGGACTGAAGT
GCGTCTCTCTGATTCAGAAGGCAAACCAGTTGGCGTCGTTTCACTGGAAGAAGCATTAAATATGGCAGTTGAATCTGATC
TAGACTTAGTTGAGATCAGCCCAAATGCCGAGCCACCAGTTTGTCGCATCATGAATTATGGCAAATTTTTGTATGAAAAG
ACTAAATCCGTTAAAGAACAACGGAAAAATCAGAAACAGGTTCAGTTAAAGGAAATAAAATTCCGTCCTGGGACTGATAT
AGGCGATTATCAGGTAAAACTACGCAACCTGACTCGCTTTTTAGAAGAGGGTAACAAAGCCAAAGTAACACTGCGTTATC
GTGGTCGTGAAATGGCACATCAATCATTAGGAATAGATCTGTTAAACCGTATTAAAGCGGATTTGGCGGAAATATCTGTT
GTCGAGTCTTTCCCGAAAATGGAAGGCCGTCAAATGGTGATGGTGTTAGGCCCCAAACGTGCTAGCTAA

Upstream 100 bases:

>100_bases
GAACTCGTAAAGGTGATGATTTAGGTAAATTCAAAGTAGACGATTTTGCCGCTTATATTAAAGAAGAAATCATCACACGC
CGTTAAATTTATTAGGAGGA

Downstream 100 bases:

>100_bases
GGCATAAAGTAGTGTTATATACCCTGTCCATTATTATGCAGCGGTATAAACATTCGCCTTACTGGTTTAATTTAAAATTT
AACAATGCGGAGTTCGCAAT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MVIKGAKKAPQQGNKHRLNDEITGTEVRLSDSEGKPVGVVSLEEALNMAVESDLDLVEISPNAEPPVCRIMNYGKFLYEK
TKSVKEQRKNQKQVQLKEIKFRPGTDIGDYQVKLRNLTRFLEEGNKAKVTLRYRGREMAHQSLGIDLLNRIKADLAEISV
VESFPKMEGRQMVMVLGPKRAS

Sequences:

>Translated_182_residues
MVIKGAKKAPQQGNKHRLNDEITGTEVRLSDSEGKPVGVVSLEEALNMAVESDLDLVEISPNAEPPVCRIMNYGKFLYEK
TKSVKEQRKNQKQVQLKEIKFRPGTDIGDYQVKLRNLTRFLEEGNKAKVTLRYRGREMAHQSLGIDLLNRIKADLAEISV
VESFPKMEGRQMVMVLGPKRAS
>Mature_182_residues
MVIKGAKKAPQQGNKHRLNDEITGTEVRLSDSEGKPVGVVSLEEALNMAVESDLDLVEISPNAEPPVCRIMNYGKFLYEK
TKSVKEQRKNQKQVQLKEIKFRPGTDIGDYQVKLRNLTRFLEEGNKAKVTLRYRGREMAHQSLGIDLLNRIKADLAEISV
VESFPKMEGRQMVMVLGPKRAS

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=179, Percent_Identity=67.5977653631285, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20552; Mature: 20552

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIKGAKKAPQQGNKHRLNDEITGTEVRLSDSEGKPVGVVSLEEALNMAVESDLDLVEIS
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHCCCCEEEEC
PNAEPPVCRIMNYGKFLYEKTKSVKEQRKNQKQVQLKEIKFRPGTDIGDYQVKLRNLTRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHEECCCCCCCCHHHHHHHHHHHH
LEEGNKAKVTLRYRGREMAHQSLGIDLLNRIKADLAEISVVESFPKMEGRQMVMVLGPKR
HHCCCCEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
AS
CC
>Mature Secondary Structure
MVIKGAKKAPQQGNKHRLNDEITGTEVRLSDSEGKPVGVVSLEEALNMAVESDLDLVEIS
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHCCCCEEEEC
PNAEPPVCRIMNYGKFLYEKTKSVKEQRKNQKQVQLKEIKFRPGTDIGDYQVKLRNLTRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHEECCCCCCCCHHHHHHHHHHHH
LEEGNKAKVTLRYRGREMAHQSLGIDLLNRIKADLAEISVVESFPKMEGRQMVMVLGPKR
HHCCCCEEEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]