Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 119945869

GI number: 119945869

Start: 2691350

End: 2692300

Strand: Direct

Name: trxB [H]

Synonym: Ping_2209

Alternate gene names: 119945869

Gene position: 2691350-2692300 (Clockwise)

Preceding gene: 119945868

Following gene: 119945881

Centisome position: 59.03

GC content: 40.9

Gene sequence:

>951_bases
ATGAGCGAAACAAAACATCAAAAATTATTAATTTTAGGTTCCGGACCTGCCGGATATACTGCAGCAGTTTATGCTGCACG
TGCCAATCTAAACCCTGTATTAATCACCGGCATGGAACAAGGTGGGCAACTTACCACAACAACTGATGTTGAAAACTGGC
CGGGTGGTTCCGCTGATATGACTGGACCCGGTTTAATGGATAGCATGAAAGATCATGCGGAACGTTTTGATACTAAAATA
ATTTTTGATCATATCAATGAAGTAGAATTAACCAAGTCCCCTTTTACCTTAAAAGGCGACAGTGATACATACAGTTGTGA
CGCTTTAATTATTGCCACAGGTGCATCGGCAACTTACTTAGGTCTTGACTCAGAAGATGCATTTAAGGGACGTGGTGTTT
CAGCTTGTGCTACTTGTGACGGTTTCTTTTACAAAAATCAAAAAGTGGCCGTGGTTGGTGGCGGTAATACTGCCGTTGAG
GAAGCATTATATTTATCAAATATTGCATCTGAAGTACATCTTATTCACCGCCGCACTGGGTTTCGCAGTGAGAAAATATT
GTTAGATAGACTCAATGCAAAAATTGCCAACGGTAATATCATTTTACATACAGACAGAACCTTAGATGAAGTATTAGGCG
ATGAGATGGGTGTAACTGGCCTGCGCTTAAAAGATACGCTGTCCGATAAAACTGAAAATCTAGAAGTAATGGGTGTTTTC
ATTGCCATTGGCCATAAACCTAATACAGGTATGTTTGCAGGACAACTTGAGATGAATCATGGTTATTTAAAAGTGCAATC
TGGTAACGATGGAAACGCAACACAGACCAGTATTAAAGGCGTCTTTGCTGCAGGTGATGTCTGTGATCATATATATCGCC
AGGCGATCACTTCATCTGGCACAGGTTGTATGGCAGCATTAGATGCTGAGCGCTACTTAGATAATCTTTAG

Upstream 100 bases:

>100_bases
CGGATATTTCAATGGAATATCCGTTTTTTTTACTGTGTTTTTTTTTCAGAGGGTTAATATTAGCCCTTATAACCTATCTC
TCTTTATTCAAGGTGTCTTT

Downstream 100 bases:

>100_bases
TGATTAACTAACATATTATCTAACTAAAAAGGTAACCATTGGCTACCTTTTTTATAAAAAGTCACTGCAACATGTAAGCA
ACGGGGTTATTTTTTATCTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSETKHQKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTDVENWPGGSADMTGPGLMDSMKDHAERFDTKI
IFDHINEVELTKSPFTLKGDSDTYSCDALIIATGASATYLGLDSEDAFKGRGVSACATCDGFFYKNQKVAVVGGGNTAVE
EALYLSNIASEVHLIHRRTGFRSEKILLDRLNAKIANGNIILHTDRTLDEVLGDEMGVTGLRLKDTLSDKTENLEVMGVF
IAIGHKPNTGMFAGQLEMNHGYLKVQSGNDGNATQTSIKGVFAAGDVCDHIYRQAITSSGTGCMAALDAERYLDNL

Sequences:

>Translated_316_residues
MSETKHQKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTDVENWPGGSADMTGPGLMDSMKDHAERFDTKI
IFDHINEVELTKSPFTLKGDSDTYSCDALIIATGASATYLGLDSEDAFKGRGVSACATCDGFFYKNQKVAVVGGGNTAVE
EALYLSNIASEVHLIHRRTGFRSEKILLDRLNAKIANGNIILHTDRTLDEVLGDEMGVTGLRLKDTLSDKTENLEVMGVF
IAIGHKPNTGMFAGQLEMNHGYLKVQSGNDGNATQTSIKGVFAAGDVCDHIYRQAITSSGTGCMAALDAERYLDNL
>Mature_315_residues
SETKHQKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTDVENWPGGSADMTGPGLMDSMKDHAERFDTKII
FDHINEVELTKSPFTLKGDSDTYSCDALIIATGASATYLGLDSEDAFKGRGVSACATCDGFFYKNQKVAVVGGGNTAVEE
ALYLSNIASEVHLIHRRTGFRSEKILLDRLNAKIANGNIILHTDRTLDEVLGDEMGVTGLRLKDTLSDKTENLEVMGVFI
AIGHKPNTGMFAGQLEMNHGYLKVQSGNDGNATQTSIKGVFAAGDVCDHIYRQAITSSGTGCMAALDAERYLDNL

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=77.2870662460568, Blast_Score=509, Evalue=1e-146,
Organism=Escherichia coli, GI87081763, Length=319, Percent_Identity=34.7962382445141, Blast_Score=147, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=44, Blast_Score=261, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6320560, Length=325, Percent_Identity=44, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33794; Mature: 33663

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETKHQKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTDVENWPGGSADM
CCCCCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCC
TGPGLMDSMKDHAERFDTKIIFDHINEVELTKSPFTLKGDSDTYSCDALIIATGASATYL
CCCCHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEECCCCCEECCEEEEEECCCEEEE
GLDSEDAFKGRGVSACATCDGFFYKNQKVAVVGGGNTAVEEALYLSNIASEVHLIHRRTG
ECCCCCCCCCCCCEEEEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
FRSEKILLDRLNAKIANGNIILHTDRTLDEVLGDEMGVTGLRLKDTLSDKTENLEVMGVF
CCCHHHHHHHHCCEEECCEEEEEECCHHHHHHCCCCCCCCEEEHHHHCCCCCCEEEEEEE
IAIGHKPNTGMFAGQLEMNHGYLKVQSGNDGNATQTSIKGVFAAGDVCDHIYRQAITSSG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHCCC
TGCMAALDAERYLDNL
CCEEEEECHHHHHCCC
>Mature Secondary Structure 
SETKHQKLLILGSGPAGYTAAVYAARANLNPVLITGMEQGGQLTTTTDVENWPGGSADM
CCCCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCC
TGPGLMDSMKDHAERFDTKIIFDHINEVELTKSPFTLKGDSDTYSCDALIIATGASATYL
CCCCHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEECCCCCEECCEEEEEECCCEEEE
GLDSEDAFKGRGVSACATCDGFFYKNQKVAVVGGGNTAVEEALYLSNIASEVHLIHRRTG
ECCCCCCCCCCCCEEEEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
FRSEKILLDRLNAKIANGNIILHTDRTLDEVLGDEMGVTGLRLKDTLSDKTENLEVMGVF
CCCHHHHHHHHCCEEECCEEEEEECCHHHHHHCCCCCCCCEEEHHHHCCCCCCEEEEEEE
IAIGHKPNTGMFAGQLEMNHGYLKVQSGNDGNATQTSIKGVFAAGDVCDHIYRQAITSSG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHCCC
TGCMAALDAERYLDNL
CCEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]