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The map label for this gene is sapA [H]

Identifier: 119945852

GI number: 119945852

Start: 2667060

End: 2668679

Strand: Direct

Name: sapA [H]

Synonym: Ping_2192

Alternate gene names: 119945852

Gene position: 2667060-2668679 (Clockwise)

Preceding gene: 119945851

Following gene: 119945853

Centisome position: 58.49

GC content: 35.37

Gene sequence:

>1620_bases
ATGATAAATTTCACCATGCGTTTTATTCTTATTTTTACTACAGCACTTATTTTAAGTGGATGTTATCAAAGCGAATCATC
ACTAAAGGATAATTTAATATACTGTCCTGAAAGTAAGGCTCTCTCTTTTAATCCACAAATCAGTCACGACATATCAAGTT
TAGATGCAACAACTCACCAGTTGTATAACCGCTTGGTTAAGAGAGATCCAACCACTCAGAACTACATTCCGGATCTTGCT
ACAGGGTGGTTGTTAAGTGAAGATAAATTAAGTTATACCTTTTTCTTACGAGAGAATGTTAACTTTCATCAAACCGAGTA
TTTTACCCCGACACGTCATTTTAAAGCTGATGATGTTATATTTAGTCTGCAAAGAATGCTTGATCAAGACCACTCTTTCC
ATTCAGTTAACCGCGGTATGGATTACTATTTTTTTAACCACCCGTTTACGCATTTAATAAGAAATATTGTCAAAATTGAT
GACTATACAATTAAGTTTATTTTAAAAAAACCAGATATAACCTTGCTTGACAGCCTAGCGGCGCATTATTCGGTGATTCT
GTCTCAAGAGTATTCCGAGCAGTTAATCGCTCGCGGCACACCTGAGAAAATTGATTTTTATCCTATTGGAACAGGTCCTT
ATAAATTTAAAAGCACTAATGATGCGGGTATTACTCACTATATTAACCATGCCAAATTTTGGGGAGGTAAGGTATCGGTA
AACAATCTTATTTTTGATGTGACGGAAAATAATACTAAACGTTATGCAAAACTGCTAACAGGTGAATGCGATATTATTGC
AAATCCGGCGCCCAGTCAGTTAAAACAGATGAGTGAAAAACCTAATATATTGCTAAGCAGTGAGCCTACCGCTAACATTC
TGCTGTGGGCATTCAACAGCAATAAAATCCCTTTTACAGAAAAAAAAATTCGCCAGGCTTTCTCTCAGGCAGTGGATCAA
AAAAATCTTTTAGAGGCAGTCTTTTATCAAAGTGCGACCGCAACAAACACCCTATTAAACCATCAATCTTGGGCATACAA
TCGCAGATCAACTGATATTCAGTACAAGCCACAGGAGGCATTAAGGACGCTGCAGGAAATGGGTTATGATTTTAACAGTA
CAATCACCCTTCTGACACCCGTCAAAAATTCTCTTTTTAACCATAGTTTCCATAAAATAGCAGAATTAATTCAAGCAAAC
TTATTAAAAATAGGCGTAAAAAGTGACATACTATTTTTAACTCAAACGGAACTTGAAAAACGTTTAATCAGTGGCAAATA
TGATACCTATTTGACTTCGGTCAATGGAAAAATAAACGATCCAGACAGTATCTTCAGACCCTTACTCAGTTGTGATTCAA
CCGTATTAGAAGGCAACTCAAGTCAATGGTGCAGTAAAGAGGTGCAATCTTTATTGAATTTAACCTTATTAGAATCAAAT
TTCACAACCCGAATAAAAAATTATTATAAACTGCAGGAAATTATTCAGGAGGAACGTATTTATTTTCCAATTGCACATGC
ATTACGTATGGATGCATTTAAGACCAACATATCTGGTTTTTTGGTTGATCCTTTTACAGGTATAAACTTCCAAAATATCA
AAAAAACAGAAGCTCACTAA

Upstream 100 bases:

>100_bases
TGTTAACCATAAACAGTAAAATTGCTCTTATCAAAACCAACCCCAAACCACTTAAAAATACCGTCTTCAGTGAGTTGGCT
ATGTTTAGATATCAAATGGG

Downstream 100 bases:

>100_bases
CTATGCTTAACTATTTATTTCGGCGCTTAAATTTATTATTAATTACAGCACTTATTCTTTCCATTATTGCATTTATCATC
TCACTTTGGTCAAATCAGGA

Product: peptide ABC transporter extracellular solute-binding protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MINFTMRFILIFTTALILSGCYQSESSLKDNLIYCPESKALSFNPQISHDISSLDATTHQLYNRLVKRDPTTQNYIPDLA
TGWLLSEDKLSYTFFLRENVNFHQTEYFTPTRHFKADDVIFSLQRMLDQDHSFHSVNRGMDYYFFNHPFTHLIRNIVKID
DYTIKFILKKPDITLLDSLAAHYSVILSQEYSEQLIARGTPEKIDFYPIGTGPYKFKSTNDAGITHYINHAKFWGGKVSV
NNLIFDVTENNTKRYAKLLTGECDIIANPAPSQLKQMSEKPNILLSSEPTANILLWAFNSNKIPFTEKKIRQAFSQAVDQ
KNLLEAVFYQSATATNTLLNHQSWAYNRRSTDIQYKPQEALRTLQEMGYDFNSTITLLTPVKNSLFNHSFHKIAELIQAN
LLKIGVKSDILFLTQTELEKRLISGKYDTYLTSVNGKINDPDSIFRPLLSCDSTVLEGNSSQWCSKEVQSLLNLTLLESN
FTTRIKNYYKLQEIIQEERIYFPIAHALRMDAFKTNISGFLVDPFTGINFQNIKKTEAH

Sequences:

>Translated_539_residues
MINFTMRFILIFTTALILSGCYQSESSLKDNLIYCPESKALSFNPQISHDISSLDATTHQLYNRLVKRDPTTQNYIPDLA
TGWLLSEDKLSYTFFLRENVNFHQTEYFTPTRHFKADDVIFSLQRMLDQDHSFHSVNRGMDYYFFNHPFTHLIRNIVKID
DYTIKFILKKPDITLLDSLAAHYSVILSQEYSEQLIARGTPEKIDFYPIGTGPYKFKSTNDAGITHYINHAKFWGGKVSV
NNLIFDVTENNTKRYAKLLTGECDIIANPAPSQLKQMSEKPNILLSSEPTANILLWAFNSNKIPFTEKKIRQAFSQAVDQ
KNLLEAVFYQSATATNTLLNHQSWAYNRRSTDIQYKPQEALRTLQEMGYDFNSTITLLTPVKNSLFNHSFHKIAELIQAN
LLKIGVKSDILFLTQTELEKRLISGKYDTYLTSVNGKINDPDSIFRPLLSCDSTVLEGNSSQWCSKEVQSLLNLTLLESN
FTTRIKNYYKLQEIIQEERIYFPIAHALRMDAFKTNISGFLVDPFTGINFQNIKKTEAH
>Mature_539_residues
MINFTMRFILIFTTALILSGCYQSESSLKDNLIYCPESKALSFNPQISHDISSLDATTHQLYNRLVKRDPTTQNYIPDLA
TGWLLSEDKLSYTFFLRENVNFHQTEYFTPTRHFKADDVIFSLQRMLDQDHSFHSVNRGMDYYFFNHPFTHLIRNIVKID
DYTIKFILKKPDITLLDSLAAHYSVILSQEYSEQLIARGTPEKIDFYPIGTGPYKFKSTNDAGITHYINHAKFWGGKVSV
NNLIFDVTENNTKRYAKLLTGECDIIANPAPSQLKQMSEKPNILLSSEPTANILLWAFNSNKIPFTEKKIRQAFSQAVDQ
KNLLEAVFYQSATATNTLLNHQSWAYNRRSTDIQYKPQEALRTLQEMGYDFNSTITLLTPVKNSLFNHSFHKIAELIQAN
LLKIGVKSDILFLTQTELEKRLISGKYDTYLTSVNGKINDPDSIFRPLLSCDSTVLEGNSSQWCSKEVQSLLNLTLLESN
FTTRIKNYYKLQEIIQEERIYFPIAHALRMDAFKTNISGFLVDPFTGINFQNIKKTEAH

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787551, Length=536, Percent_Identity=32.089552238806, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1789966, Length=520, Percent_Identity=31.7307692307692, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI1787052, Length=469, Percent_Identity=25.5863539445629, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1787762, Length=502, Percent_Identity=21.9123505976096, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789887, Length=499, Percent_Identity=22.6452905811623, Blast_Score=95, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62074; Mature: 62074

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINFTMRFILIFTTALILSGCYQSESSLKDNLIYCPESKALSFNPQISHDISSLDATTHQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCHHHHHHHHHHHHHH
LYNRLVKRDPTTQNYIPDLATGWLLSEDKLSYTFFLRENVNFHQTEYFTPTRHFKADDVI
HHHHHHHCCCCCCCCCCCHHHCCEEECCCCEEEEEEECCCCCCEEECCCCCCCCCHHHHH
FSLQRMLDQDHSFHSVNRGMDYYFFNHPFTHLIRNIVKIDDYTIKFILKKPDITLLDSLA
HHHHHHHHCCCCHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHH
AHYSVILSQEYSEQLIARGTPEKIDFYPIGTGPYKFKSTNDAGITHYINHAKFWGGKVSV
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCEEEE
NNLIFDVTENNTKRYAKLLTGECDIIANPAPSQLKQMSEKPNILLSSEPTANILLWAFNS
CCEEEEEECCCHHHHHHHHCCCCCEEECCCHHHHHHHHCCCCEEEECCCCCEEEEEEECC
NKIPFTEKKIRQAFSQAVDQKNLLEAVFYQSATATNTLLNHQSWAYNRRSTDIQYKPQEA
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCEECHHHH
LRTLQEMGYDFNSTITLLTPVKNSLFNHSFHKIAELIQANLLKIGVKSDILFLTQTELEK
HHHHHHCCCCCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHEEECCCCEEEEEHHHHHH
RLISGKYDTYLTSVNGKINDPDSIFRPLLSCDSTVLEGNSSQWCSKEVQSLLNLTLLESN
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCC
FTTRIKNYYKLQEIIQEERIYFPIAHALRMDAFKTNISGFLVDPFTGINFQNIKKTEAH
HHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MINFTMRFILIFTTALILSGCYQSESSLKDNLIYCPESKALSFNPQISHDISSLDATTHQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCHHHHHHHHHHHHHH
LYNRLVKRDPTTQNYIPDLATGWLLSEDKLSYTFFLRENVNFHQTEYFTPTRHFKADDVI
HHHHHHHCCCCCCCCCCCHHHCCEEECCCCEEEEEEECCCCCCEEECCCCCCCCCHHHHH
FSLQRMLDQDHSFHSVNRGMDYYFFNHPFTHLIRNIVKIDDYTIKFILKKPDITLLDSLA
HHHHHHHHCCCCHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHH
AHYSVILSQEYSEQLIARGTPEKIDFYPIGTGPYKFKSTNDAGITHYINHAKFWGGKVSV
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCEEEE
NNLIFDVTENNTKRYAKLLTGECDIIANPAPSQLKQMSEKPNILLSSEPTANILLWAFNS
CCEEEEEECCCHHHHHHHHCCCCCEEECCCHHHHHHHHCCCCEEEECCCCCEEEEEEECC
NKIPFTEKKIRQAFSQAVDQKNLLEAVFYQSATATNTLLNHQSWAYNRRSTDIQYKPQEA
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCEECHHHH
LRTLQEMGYDFNSTITLLTPVKNSLFNHSFHKIAELIQANLLKIGVKSDILFLTQTELEK
HHHHHHCCCCCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHEEECCCCEEEEEHHHHHH
RLISGKYDTYLTSVNGKINDPDSIFRPLLSCDSTVLEGNSSQWCSKEVQSLLNLTLLESN
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCC
FTTRIKNYYKLQEIIQEERIYFPIAHALRMDAFKTNISGFLVDPFTGINFQNIKKTEAH
HHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8223423; 11677609 [H]