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The map label for this gene is ina [H]

Identifier: 119945807

GI number: 119945807

Start: 2616617

End: 2618158

Strand: Direct

Name: ina [H]

Synonym: Ping_2144

Alternate gene names: 119945807

Gene position: 2616617-2618158 (Clockwise)

Preceding gene: 119945805

Following gene: 119945808

Centisome position: 57.39

GC content: 44.55

Gene sequence:

>1542_bases
ATGTGTAATGACTTATGCATAATGCCCCCCTCTCCAGATCTGCACAACAAAATAGACGAGTCTAAACGTGCATTCCTAAA
GGGAAGTCTTCTTGGTATAGATCAGGTAGATTTACTCGACATGCGAACATTTACCTTGATCACCGGGCGTCCGGCAAAAA
CCCGTTCACACAACAATTCGCTAGAGTCTGCTTCTGTAAAAGGAGTACGTAAAGCACTGGTTTTATTAGTGGACTTCTCT
GACAAAAAAGCCACTGAACCCAAAAGTCACTTCAATGATCTCATGTTTTCATTAAGTAAAAACAGCATGCGGGATTACTA
CCGCGAAGTTTCCTATAATAATCTGGATGTACAAGGTGAAGTAGCAGGCAGTGGCCCAACTAAAGATTGGTTTCGTGCGC
CCAAGCCAAAAAGTTATTATACCAATAATGACTTTGGCTTCGGCAGCTACCCGCAAAACGCACAAAAACTGGTCGAGGAC
GTCATTGATTTAGCGGCATCGCACGTCAACTTTGCCGATTATGATAATTCCGGCGATGGAAAAGTTGAATCCTTAGTGAT
CATCTGCGCTGGCATCGGTGGCGAGCAATCTGGTAACAAGACTGACTTATGGTCACATAAATGGAGCATAGTACCAAAGT
CGGTCGATGGGGTGATCGTTGATCGTTATTTCATGGCACCAGAAAATGGAAAAGTAGGAGTAATGGCACACGAACTTGGG
CATCTGCTAATGGGGTGGCCTGACTTATATGATACCGACTACTCCAGTCGAGGTACCGGACGCTGGGATCTAATGGCCGG
AGGTAGCTGGAATAATAATGGCGACACCCCGGCTCACCCTACTGCCTGGTGTAAAGAGAAAGCAGGCTGGATCACGCCAA
CGGTTATTTTTTCTGCCGATCAGGCAATCAATCTGCAACCCTATGCAGATCATGCCCAAGCTTATAAATTGCCCATTGGC
AGTGCAGGCAGTAAAGAGTACTTTTTGCTCAGTAACCGAAAAAAGCGCGGCTTTGATCTACATTTGCCCGGTGAAGGTAT
GATTATTGAGCATATTGATGACAATAAAATCAATAACACCGACGAAAACCATTATCTGGTAGACATAAAGCAATGTGATG
GACTGAGGGAGCTAAACTTAAACATTAATAGCGGAAACGCGGGTGATGCTTACCCTAGTACTGCTAACAATTCATTCACT
AATAGCACTTCGCCAAGCAGCAAAAGTTACGCTGGCGCAGACTCCAAGATAGCGGTAACCAATATCACTCAGTCCGGTGA
CAACGTGACAGCTAATGTCAATGTTGGTGGGGCTACAGCTAAGGTTTGGAAGAATAATGTGGCCATTAGCAAAACTTATG
CGACTTACCACAGCAAAAATGCCTGGGCATACATTGCCGGTGCCGGCTGGCGCAAAATAGATGGTCTGTCAACCGATGGT
GTTACCAATGTATTTATATTACTGGTCTATGCACAAGCGTTCAACAGAAATGTTTCAGTACAAATTGATGGCGATAAAAT
CTATACCGCTTATATGAACTAG

Upstream 100 bases:

>100_bases
AAAAGTGTATTACAAAAAGTTACTTGTAGGCTGTAACGATTTTAATGCCTGATTTAAATAAAAGTTATTGGTTGATTTTG
ATTGATAAGGATATATCACT

Downstream 100 bases:

>100_bases
GAGAGATAAAATGAATTTTTCAAACAAAGCTGTAACACGCACTTACGCAACGCCTCATTCTCAAAATTGCTGGGCTTATC
TTGCCACTATTGGCTGGAGA

Product: peptidase M6, immune inhibitor A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MCNDLCIMPPSPDLHNKIDESKRAFLKGSLLGIDQVDLLDMRTFTLITGRPAKTRSHNNSLESASVKGVRKALVLLVDFS
DKKATEPKSHFNDLMFSLSKNSMRDYYREVSYNNLDVQGEVAGSGPTKDWFRAPKPKSYYTNNDFGFGSYPQNAQKLVED
VIDLAASHVNFADYDNSGDGKVESLVIICAGIGGEQSGNKTDLWSHKWSIVPKSVDGVIVDRYFMAPENGKVGVMAHELG
HLLMGWPDLYDTDYSSRGTGRWDLMAGGSWNNNGDTPAHPTAWCKEKAGWITPTVIFSADQAINLQPYADHAQAYKLPIG
SAGSKEYFLLSNRKKRGFDLHLPGEGMIIEHIDDNKINNTDENHYLVDIKQCDGLRELNLNINSGNAGDAYPSTANNSFT
NSTSPSSKSYAGADSKIAVTNITQSGDNVTANVNVGGATAKVWKNNVAISKTYATYHSKNAWAYIAGAGWRKIDGLSTDG
VTNVFILLVYAQAFNRNVSVQIDGDKIYTAYMN

Sequences:

>Translated_513_residues
MCNDLCIMPPSPDLHNKIDESKRAFLKGSLLGIDQVDLLDMRTFTLITGRPAKTRSHNNSLESASVKGVRKALVLLVDFS
DKKATEPKSHFNDLMFSLSKNSMRDYYREVSYNNLDVQGEVAGSGPTKDWFRAPKPKSYYTNNDFGFGSYPQNAQKLVED
VIDLAASHVNFADYDNSGDGKVESLVIICAGIGGEQSGNKTDLWSHKWSIVPKSVDGVIVDRYFMAPENGKVGVMAHELG
HLLMGWPDLYDTDYSSRGTGRWDLMAGGSWNNNGDTPAHPTAWCKEKAGWITPTVIFSADQAINLQPYADHAQAYKLPIG
SAGSKEYFLLSNRKKRGFDLHLPGEGMIIEHIDDNKINNTDENHYLVDIKQCDGLRELNLNINSGNAGDAYPSTANNSFT
NSTSPSSKSYAGADSKIAVTNITQSGDNVTANVNVGGATAKVWKNNVAISKTYATYHSKNAWAYIAGAGWRKIDGLSTDG
VTNVFILLVYAQAFNRNVSVQIDGDKIYTAYMN
>Mature_513_residues
MCNDLCIMPPSPDLHNKIDESKRAFLKGSLLGIDQVDLLDMRTFTLITGRPAKTRSHNNSLESASVKGVRKALVLLVDFS
DKKATEPKSHFNDLMFSLSKNSMRDYYREVSYNNLDVQGEVAGSGPTKDWFRAPKPKSYYTNNDFGFGSYPQNAQKLVED
VIDLAASHVNFADYDNSGDGKVESLVIICAGIGGEQSGNKTDLWSHKWSIVPKSVDGVIVDRYFMAPENGKVGVMAHELG
HLLMGWPDLYDTDYSSRGTGRWDLMAGGSWNNNGDTPAHPTAWCKEKAGWITPTVIFSADQAINLQPYADHAQAYKLPIG
SAGSKEYFLLSNRKKRGFDLHLPGEGMIIEHIDDNKINNTDENHYLVDIKQCDGLRELNLNINSGNAGDAYPSTANNSFT
NSTSPSSKSYAGADSKIAVTNITQSGDNVTANVNVGGATAKVWKNNVAISKTYATYHSKNAWAYIAGAGWRKIDGLSTDG
VTNVFILLVYAQAFNRNVSVQIDGDKIYTAYMN

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 56322; Mature: 56322

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNDLCIMPPSPDLHNKIDESKRAFLKGSLLGIDQVDLLDMRTFTLITGRPAKTRSHNNS
CCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECEEEEEEECCCCCCCCCCCC
LESASVKGVRKALVLLVDFSDKKATEPKSHFNDLMFSLSKNSMRDYYREVSYNNLDVQGE
CCHHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VAGSGPTKDWFRAPKPKSYYTNNDFGFGSYPQNAQKLVEDVIDLAASHVNFADYDNSGDG
ECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCC
KVESLVIICAGIGGEQSGNKTDLWSHKWSIVPKSVDGVIVDRYFMAPENGKVGVMAHELG
CEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEHHHHH
HLLMGWPDLYDTDYSSRGTGRWDLMAGGSWNNNGDTPAHPTAWCKEKAGWITPTVIFSAD
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECC
QAINLQPYADHAQAYKLPIGSAGSKEYFLLSNRKKRGFDLHLPGEGMIIEHIDDNKINNT
CEEECCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCC
DENHYLVDIKQCDGLRELNLNINSGNAGDAYPSTANNSFTNSTSPSSKSYAGADSKIAVT
CCCEEEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
NITQSGDNVTANVNVGGATAKVWKNNVAISKTYATYHSKNAWAYIAGAGWRKIDGLSTDG
EEECCCCCEEEEEECCCCEEEEECCCEEEEEEEEEEECCCCEEEEECCCCEEECCCCCCC
VTNVFILLVYAQAFNRNVSVQIDGDKIYTAYMN
HHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEC
>Mature Secondary Structure
MCNDLCIMPPSPDLHNKIDESKRAFLKGSLLGIDQVDLLDMRTFTLITGRPAKTRSHNNS
CCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECEEEEEEECCCCCCCCCCCC
LESASVKGVRKALVLLVDFSDKKATEPKSHFNDLMFSLSKNSMRDYYREVSYNNLDVQGE
CCHHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VAGSGPTKDWFRAPKPKSYYTNNDFGFGSYPQNAQKLVEDVIDLAASHVNFADYDNSGDG
ECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCC
KVESLVIICAGIGGEQSGNKTDLWSHKWSIVPKSVDGVIVDRYFMAPENGKVGVMAHELG
CEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEHHHHH
HLLMGWPDLYDTDYSSRGTGRWDLMAGGSWNNNGDTPAHPTAWCKEKAGWITPTVIFSAD
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECC
QAINLQPYADHAQAYKLPIGSAGSKEYFLLSNRKKRGFDLHLPGEGMIIEHIDDNKINNT
CEEECCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCC
DENHYLVDIKQCDGLRELNLNINSGNAGDAYPSTANNSFTNSTSPSSKSYAGADSKIAVT
CCCEEEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
NITQSGDNVTANVNVGGATAKVWKNNVAISKTYATYHSKNAWAYIAGAGWRKIDGLSTDG
EEECCCCCEEEEEECCCCEEEEECCCEEEEEEEEEEECCCCEEEEECCCCEEECCCCCCC
VTNVFILLVYAQAFNRNVSVQIDGDKIYTAYMN
HHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]