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The map label for this gene is glpR [H]

Identifier: 119945758

GI number: 119945758

Start: 2546579

End: 2547346

Strand: Reverse

Name: glpR [H]

Synonym: Ping_2091

Alternate gene names: 119945758

Gene position: 2547346-2546579 (Counterclockwise)

Preceding gene: 119945759

Following gene: 119945757

Centisome position: 55.87

GC content: 44.14

Gene sequence:

>768_bases
ATGCAGAAACTCAGTCTTCGTCAACAGACAATAATAGATATGATTGGTCATCAAGAGTATTGCTCTATTGATGAACTCGC
TCAACATTTTAATGTCACCACACAAACTATCCGCCGAGATATCAATCAACTCTGTGCGATAGGACTCGCATGTCGCCATC
ACGGTGGTGTTGGTTTACCTGTCACTTTAGCCAACCGCAGTTATGTTTCCCGAAAAGTGACTAATCAAGCAGAAAAGCAG
CATATTGCAGCATCTGTTGTTGCCGCGATCCCTAATGGTTGTACCTTATTTCTGGGGATAGGCACTACGATCGCGGGCAT
CGCAGAAAAGCTGGTCAATCATAGCGAGCTTAGGGTCGTCACCAATAACTTTGAAGCTGCTCATCTGTTATCACAATTTG
ATAATATCGAAACCTGGATCCCGGGAGGGCGTATTCGAAGTAATGATCGCGATGTTGTTGGAGACAGCATCGGAGCGTTT
TATGGTCAGTTTATTGCCGATATTGGTATTATCAGTTGTGGATCAATCAATCCTATCGAAAAACCCGTCGCGTTAAACAG
TTTGGCAGTACAATCCGAGGGTGAGATGCAGGAATATGCTTTTGAATATGAACTGCGCGAAGCCATTGTCAGCCAAGCCA
TTATTTCGGGTTCCAGGCAAAAGTGGCTGGTGGCAAACAGTGCAAAACGGCAACAAAAAGCCAATGCCAAAGTTGCCCCT
CTAAGTCATTTTGATCGTGTATTTGGTGGTGTTACAGATAAAAATTGA

Upstream 100 bases:

>100_bases
ACAAGCCTATATCAATATTTTGACCTACGATAAATTTAAATTAATAAACTCTAATTAATAAACTCTAATTAATAAACAAG
GCAGGAACCTCACACTAGCC

Downstream 100 bases:

>100_bases
TAGGGCCTGTGCGCCAAAATAGTTGGCATACAGCGACTTGTTTTTTTGTATACCCCTTGAGATTGCCATAGTAAAATAAA
TAATTAAGATTCTAATTTAA

Product: transcriptional regulator for glycerol-3-phosphate regulon, DeoR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MQKLSLRQQTIIDMIGHQEYCSIDELAQHFNVTTQTIRRDINQLCAIGLACRHHGGVGLPVTLANRSYVSRKVTNQAEKQ
HIAASVVAAIPNGCTLFLGIGTTIAGIAEKLVNHSELRVVTNNFEAAHLLSQFDNIETWIPGGRIRSNDRDVVGDSIGAF
YGQFIADIGIISCGSINPIEKPVALNSLAVQSEGEMQEYAFEYELREAIVSQAIISGSRQKWLVANSAKRQQKANAKVAP
LSHFDRVFGGVTDKN

Sequences:

>Translated_255_residues
MQKLSLRQQTIIDMIGHQEYCSIDELAQHFNVTTQTIRRDINQLCAIGLACRHHGGVGLPVTLANRSYVSRKVTNQAEKQ
HIAASVVAAIPNGCTLFLGIGTTIAGIAEKLVNHSELRVVTNNFEAAHLLSQFDNIETWIPGGRIRSNDRDVVGDSIGAF
YGQFIADIGIISCGSINPIEKPVALNSLAVQSEGEMQEYAFEYELREAIVSQAIISGSRQKWLVANSAKRQQKANAKVAP
LSHFDRVFGGVTDKN
>Mature_255_residues
MQKLSLRQQTIIDMIGHQEYCSIDELAQHFNVTTQTIRRDINQLCAIGLACRHHGGVGLPVTLANRSYVSRKVTNQAEKQ
HIAASVVAAIPNGCTLFLGIGTTIAGIAEKLVNHSELRVVTNNFEAAHLLSQFDNIETWIPGGRIRSNDRDVVGDSIGAF
YGQFIADIGIISCGSINPIEKPVALNSLAVQSEGEMQEYAFEYELREAIVSQAIISGSRQKWLVANSAKRQQKANAKVAP
LSHFDRVFGGVTDKN

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=246, Percent_Identity=36.9918699186992, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI87082344, Length=242, Percent_Identity=33.4710743801653, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI226510968, Length=246, Percent_Identity=29.6747967479675, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789059, Length=242, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=26.6932270916335, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789519, Length=154, Percent_Identity=27.9220779220779, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27885; Mature: 27885

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLSLRQQTIIDMIGHQEYCSIDELAQHFNVTTQTIRRDINQLCAIGLACRHHGGVGLP
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VTLANRSYVSRKVTNQAEKQHIAASVVAAIPNGCTLFLGIGTTIAGIAEKLVNHSELRVV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEE
TNNFEAAHLLSQFDNIETWIPGGRIRSNDRDVVGDSIGAFYGQFIADIGIISCGSINPIE
ECCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCCCCCCC
KPVALNSLAVQSEGEMQEYAFEYELREAIVSQAIISGSRQKWLVANSAKRQQKANAKVAP
CCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCC
LSHFDRVFGGVTDKN
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKLSLRQQTIIDMIGHQEYCSIDELAQHFNVTTQTIRRDINQLCAIGLACRHHGGVGLP
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VTLANRSYVSRKVTNQAEKQHIAASVVAAIPNGCTLFLGIGTTIAGIAEKLVNHSELRVV
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEE
TNNFEAAHLLSQFDNIETWIPGGRIRSNDRDVVGDSIGAFYGQFIADIGIISCGSINPIE
ECCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCCCCCCC
KPVALNSLAVQSEGEMQEYAFEYELREAIVSQAIISGSRQKWLVANSAKRQQKANAKVAP
CCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCC
LSHFDRVFGGVTDKN
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]