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The map label for this gene is gntR [H]

Identifier: 119945730

GI number: 119945730

Start: 2505472

End: 2506497

Strand: Direct

Name: gntR [H]

Synonym: Ping_2058

Alternate gene names: 119945730

Gene position: 2505472-2506497 (Clockwise)

Preceding gene: 119945724

Following gene: 119945733

Centisome position: 54.95

GC content: 39.08

Gene sequence:

>1026_bases
ATGGAAGTGACTCGTAAACGTCGCGGGACAGGACGTGTAACATTAGCAGATGTAGCAAAAGCAGCAGGCGTAGGAACGAT
GACGGTATCTAGGGTATTAAGAATGCCCGATCAGGTTTCCGATAAACTAAGGGATAAAATACAGCAAGTTATTGATGAAT
TAGGTTATATACCTAATCGTGCCGCAGGTGCATTAGCCTCTGGGAAAAGTAACTCGATTGCGGTGATCCTTCCCTCTTTA
GTTGATAAAATGTGTTCTCAATTTATCCCCCCATTTCAAAATATACTCAATCAGGCAGGTCACCAACTAATATTGGGTTA
CAGCAATTATTCAATTTCACAAGAAGAGCAGTTACTTTCTCCTTTATTAGCAAGCAACCCCTCTGCCATCGTGCTTTTCG
GTAGCGAGCGATCTGCCCAATCGACAAAAATGATTAAAAACGCTCAGCTTACTATGCTTGAAGTGGCTGAAATAAATGAT
CTTTCCTTTGATTTAAATATTGGTATTGATCATTATCAGGCAAGCAAAGAGATGACGAATTATTTAATTAAAAAAGGTTA
TCAGAATATTGCTTTTGTCGGTTTCCAAAACGGACAAAATATTTTACGTAAGCAACTAGGTGGTTGGCAGTCAGCTATGC
TGGAAAATTACTTATCTCCAGATCATTTTTTAATAGCCAATGATCTTACTGATATAAAATTAGGCAGTGAAGGGCTCGCT
AAATTATTATTGCGGGAGAGTACGCTAGATGCTGTTATCTGCACTAATGAAGAGATTGCAACAGGCGTGTTGTTTGAATG
CCAACGACGTGTTCTTAAAATTCCGCAAGATATTGCTATAACATGTCTAGATGGTTCAATACTCAGTCAGCAATGTGTAC
CGACACTGACCAGTATCGAGCTTGACTACGTGAACATGGGTAAAGAAGCAGCCAATCTATTACTGGAAAGATTATTGGAT
AAAGAGCAGAGTGATGCTAAACAAATTAATATCGGTTTTAAGCTTTGTGAACGAGCAAGCAGTTGA

Upstream 100 bases:

>100_bases
TTATAATGCTACCCTCAGATGGTCTGCAACAGAGAAATCATAAAATTTAAAATGGCAGCTTATAACGCCACACTATTAAA
AATAATATTCAGGACATTTT

Downstream 100 bases:

>100_bases
CCTTTAAAAGACCAAAAAGCAATGTATTATATTGCTTTTTGGTACTTAACAGCCCAATAAAATACCTTTCTACGCACTAG
ACTCTCTTTTAGTAAAGCAC

Product: transcriptional regulator of LacI family protein

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MEVTRKRRGTGRVTLADVAKAAGVGTMTVSRVLRMPDQVSDKLRDKIQQVIDELGYIPNRAAGALASGKSNSIAVILPSL
VDKMCSQFIPPFQNILNQAGHQLILGYSNYSISQEEQLLSPLLASNPSAIVLFGSERSAQSTKMIKNAQLTMLEVAEIND
LSFDLNIGIDHYQASKEMTNYLIKKGYQNIAFVGFQNGQNILRKQLGGWQSAMLENYLSPDHFLIANDLTDIKLGSEGLA
KLLLRESTLDAVICTNEEIATGVLFECQRRVLKIPQDIAITCLDGSILSQQCVPTLTSIELDYVNMGKEAANLLLERLLD
KEQSDAKQINIGFKLCERASS

Sequences:

>Translated_341_residues
MEVTRKRRGTGRVTLADVAKAAGVGTMTVSRVLRMPDQVSDKLRDKIQQVIDELGYIPNRAAGALASGKSNSIAVILPSL
VDKMCSQFIPPFQNILNQAGHQLILGYSNYSISQEEQLLSPLLASNPSAIVLFGSERSAQSTKMIKNAQLTMLEVAEIND
LSFDLNIGIDHYQASKEMTNYLIKKGYQNIAFVGFQNGQNILRKQLGGWQSAMLENYLSPDHFLIANDLTDIKLGSEGLA
KLLLRESTLDAVICTNEEIATGVLFECQRRVLKIPQDIAITCLDGSILSQQCVPTLTSIELDYVNMGKEAANLLLERLLD
KEQSDAKQINIGFKLCERASS
>Mature_341_residues
MEVTRKRRGTGRVTLADVAKAAGVGTMTVSRVLRMPDQVSDKLRDKIQQVIDELGYIPNRAAGALASGKSNSIAVILPSL
VDKMCSQFIPPFQNILNQAGHQLILGYSNYSISQEEQLLSPLLASNPSAIVLFGSERSAQSTKMIKNAQLTMLEVAEIND
LSFDLNIGIDHYQASKEMTNYLIKKGYQNIAFVGFQNGQNILRKQLGGWQSAMLENYLSPDHFLIANDLTDIKLGSEGLA
KLLLRESTLDAVICTNEEIATGVLFECQRRVLKIPQDIAITCLDGSILSQQCVPTLTSIELDYVNMGKEAANLLLERLLD
KEQSDAKQINIGFKLCERASS

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=33.7386018237082, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=27.0769230769231, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790369, Length=308, Percent_Identity=26.9480519480519, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=24.2424242424242, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=26.3333333333333, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788474, Length=306, Percent_Identity=25.1633986928105, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787906, Length=255, Percent_Identity=27.843137254902, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789202, Length=304, Percent_Identity=23.6842105263158, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790194, Length=307, Percent_Identity=24.7557003257329, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786540, Length=317, Percent_Identity=25.5520504731861, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790689, Length=333, Percent_Identity=24.6246246246246, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787580, Length=322, Percent_Identity=24.223602484472, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37496; Mature: 37496

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTRKRRGTGRVTLADVAKAAGVGTMTVSRVLRMPDQVSDKLRDKIQQVIDELGYIPNR
CCCCCCCCCCCCEEHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
AAGALASGKSNSIAVILPSLVDKMCSQFIPPFQNILNQAGHQLILGYSNYSISQEEQLLS
HHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
PLLASNPSAIVLFGSERSAQSTKMIKNAQLTMLEVAEINDLSFDLNIGIDHYQASKEMTN
HHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHH
YLIKKGYQNIAFVGFQNGQNILRKQLGGWQSAMLENYLSPDHFLIANDLTDIKLGSEGLA
HHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCEEECHHHHH
KLLLRESTLDAVICTNEEIATGVLFECQRRVLKIPQDIAITCLDGSILSQQCVPTLTSIE
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCHHHHEE
LDYVNMGKEAANLLLERLLDKEQSDAKQINIGFKLCERASS
EHHHHCCHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHCCC
>Mature Secondary Structure
MEVTRKRRGTGRVTLADVAKAAGVGTMTVSRVLRMPDQVSDKLRDKIQQVIDELGYIPNR
CCCCCCCCCCCCEEHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
AAGALASGKSNSIAVILPSLVDKMCSQFIPPFQNILNQAGHQLILGYSNYSISQEEQLLS
HHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
PLLASNPSAIVLFGSERSAQSTKMIKNAQLTMLEVAEINDLSFDLNIGIDHYQASKEMTN
HHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHH
YLIKKGYQNIAFVGFQNGQNILRKQLGGWQSAMLENYLSPDHFLIANDLTDIKLGSEGLA
HHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCEEECHHHHH
KLLLRESTLDAVICTNEEIATGVLFECQRRVLKIPQDIAITCLDGSILSQQCVPTLTSIE
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCHHHHEE
LDYVNMGKEAANLLLERLLDKEQSDAKQINIGFKLCERASS
EHHHHCCHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]