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The map label for this gene is silP [H]

Identifier: 119945703

GI number: 119945703

Start: 2461184

End: 2463613

Strand: Reverse

Name: silP [H]

Synonym: Ping_2020

Alternate gene names: 119945703

Gene position: 2463613-2461184 (Counterclockwise)

Preceding gene: 119945706

Following gene: 119945696

Centisome position: 54.03

GC content: 52.59

Gene sequence:

>2430_bases
ATGAGTGCAAAACTAAATAAAGAACAAGACCAGCTTAACGATCCAGTCTGTGACATGTCGGTATCACATGACTCCAAACA
CACTTACGATTATGCCGATAAACAGTATTTATTCTGCAGTGAACACTGCCTGAAGAAATTCAAGGAGCAGCCTGAACAGT
ATCTGGATAAGGAAACGTCCCCACCAAGTAAAACAGAGGGTGAGTCAAAGACCTACACCTGCCCCATGCATCCTGAAATT
CAACAGCACGATCCCGGAACCTGCCCAAAATGCGGGATGGCGCTGGAGACGATAGGCGTGTCGGCAACGGCGACGGCAAC
CACCTATACCTGTCCCATGCATCCTGACGTTACTCAGGATAGCCCCGGTAATTGCCCCAAGTGCGGAATGGCTCTGGAGG
GGGAGACATCCGGCGGTGAACAAAAAAATGAAGAGCTTATCGATATGAGCCGGCGTTTTTGGGGTTGTACCGCGCTCGCT
CTGCCGGTCTTTTTTCTGGCCATGACTGCCGATATGCTGCCTGGCTGGTTACCAAACTGGCTGTCGCTGCAGATGGTGCA
ATGGATTGAATGTGCGCTGGCGACACCTGTTGTTGTCTGGGGCGGTTGGCCATTTTTTGTGCGCGGCTGGCAATCTGTCC
GGACCTGGAACCTGAATATGTTTACCCTGATCGCGCTGGGTGTCTCGGTCTCCTGGAGCTACAGCATGGTGGCTCTGTTG
TTACCCGGGCTCTTTCCAACCATCATGCAGATGTCTGACGGGCTGGTGCCTGTTTATTTTGAAGCTGCGGCCATGATCAC
AACCCTAGTTCTGCTTGGGCAGGTGCTTGAATTGCGCGCCCGCTCTCGAACCAATGCGGCCATTGAGATGCTGCTCAGTC
TTGCTCCTAATACAGCCCGTATCGTACGGGAGGATGGAACGGAAGAGGATATCCCGCTGGATCAGGTACAGTCCGGTGCT
ACCTTGCGTGTTCGTCCCGGTGATAAAGTACCGGTAGATGGTACGGTTATCGAAGGAGATAGCAACATTGATGAATCCAT
GGTCACCGGCGAATCGCTCCCGGTGACAAAATCAGCCGGTGAGAAGCTGATCGGCGCGACGGTTAATGGAACTGGCAGTT
TATTAATGCGGGCAGAAAAAGTTGGTTCCGATACTCTGTTGGCACAAATTGTCGATATGGTAGCCAAAGCACAGCGTACG
CGAGCGCCCATTCAAAAGTTGGCCGATCTCGTGGCGGGATATTTTGTCCCTGCTATTGTGGGTTGTGCTGTGCTTACTTT
TGCCGTGTGGTTCGGATGGGGGCCGGAACCGCGTCTGGCACATGCCGTAGTCAATGCGGTTGCGGTATTGATCATCGCCT
GTCCCTGCGCATTGGGACTTGCTACACCCATTTCGATTATGGTCGGGACGGGGCGCGGTGCCACGGCCGGTGTTTTGATC
AAGAATGCCGAAGCGCTGGAGATCATGGAAAAGGTCGATACTCTGGTGGTGGACAAGACCGGTACGCTGACCGAGGGTAA
GCCAAAGCTGGTTGCAGTGCAGGCGGAAGAGGGATTTGACGAGGATCAACTGGTACGTCTGGTCGCCAGCCTCGAACGGG
CTAGCGAACACCCTTTGGCGGAAGCCATTGTGCGTGGTGCTGAAGAAAAGGGTATCAAGCTGGTTAAGGCCGATAATTTT
AAGTCGCTGACCGGAAAAGGGGTCACCGGTGAGGTTGATGGAGAATCTGTCGCAGCGGGCAATGTTGCACTGATGGAAAG
TCTGGGAATCAACGTGGAAAATTTATCTCAACAAGCAGACCAGCAACGCGCCGAAGGACAGACGGTTATGCTGATTGCCA
TCAATGGCAAGGCAGCGGGGTTAATCGGCGTCGCTGATCCGATCAAGGAGTCAACTGCCGAAGCCATTCGTGATTTGCAT
GGCGAAGGTATCAAAATAGTGATGATTACCGGTGACAATCAGATCACTGCCAAGGCGGTTGCAGGCAAGCTGGAAATCGA
TCAGGTACATGCCGAAGTACTGCCTGAAGAGAAAGCTACACTTATCAAAAAACTTCAGGCAGAAGGCCATATTGTTGCCA
TGGCGGGTGACGGCATCAACGATGCGCCGGCACTGGCTCAGGCTCATGTCGGTATTGCCATGGGCACTGGCACCGATGTG
GCCATAGAAAGCGCCAGCATCACTTTAGTCAAAGGCGATTTACGGGGCATTGTCAGGGCCAGACGATTAAGCCGGGCCAC
TATGCGTAATATCAGGCAGAATTTATTTTTCGCTTTCTTTTACAACTCGGCGGGTGTGCCGATTGCCGCGGGAGTACTGT
TTCCCTTCTTTGGCATATTGCTGTCACCAATGATCGCTGCCGCAGCCATGAGCTTCAGCTCCGTTTCAGTGATCAGTAAT
TCACTGAGACTAAAGAGGGTGAAATTATAA

Upstream 100 bases:

>100_bases
CGGTTTTATAGTTTTTTAAGGCGAATAGTTGTACCATTTAACGACAAAGAGCACATAAATAGCCAATTTTTGATTAGGTT
TCTAGAAGGAAGATGGAGAT

Downstream 100 bases:

>100_bases
AACGTAAAAAATTAATGTCTGGCTAACTAATAAGAATAGGTCGTGTGAGCAGGTTGTTTAAACACCTAACGATCCGTTAG
GTGTTATCTGCATTGCCATA

Product: heavy metal translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 809; Mature: 808

Protein sequence:

>809_residues
MSAKLNKEQDQLNDPVCDMSVSHDSKHTYDYADKQYLFCSEHCLKKFKEQPEQYLDKETSPPSKTEGESKTYTCPMHPEI
QQHDPGTCPKCGMALETIGVSATATATTYTCPMHPDVTQDSPGNCPKCGMALEGETSGGEQKNEELIDMSRRFWGCTALA
LPVFFLAMTADMLPGWLPNWLSLQMVQWIECALATPVVVWGGWPFFVRGWQSVRTWNLNMFTLIALGVSVSWSYSMVALL
LPGLFPTIMQMSDGLVPVYFEAAAMITTLVLLGQVLELRARSRTNAAIEMLLSLAPNTARIVREDGTEEDIPLDQVQSGA
TLRVRPGDKVPVDGTVIEGDSNIDESMVTGESLPVTKSAGEKLIGATVNGTGSLLMRAEKVGSDTLLAQIVDMVAKAQRT
RAPIQKLADLVAGYFVPAIVGCAVLTFAVWFGWGPEPRLAHAVVNAVAVLIIACPCALGLATPISIMVGTGRGATAGVLI
KNAEALEIMEKVDTLVVDKTGTLTEGKPKLVAVQAEEGFDEDQLVRLVASLERASEHPLAEAIVRGAEEKGIKLVKADNF
KSLTGKGVTGEVDGESVAAGNVALMESLGINVENLSQQADQQRAEGQTVMLIAINGKAAGLIGVADPIKESTAEAIRDLH
GEGIKIVMITGDNQITAKAVAGKLEIDQVHAEVLPEEKATLIKKLQAEGHIVAMAGDGINDAPALAQAHVGIAMGTGTDV
AIESASITLVKGDLRGIVRARRLSRATMRNIRQNLFFAFFYNSAGVPIAAGVLFPFFGILLSPMIAAAAMSFSSVSVISN
SLRLKRVKL

Sequences:

>Translated_809_residues
MSAKLNKEQDQLNDPVCDMSVSHDSKHTYDYADKQYLFCSEHCLKKFKEQPEQYLDKETSPPSKTEGESKTYTCPMHPEI
QQHDPGTCPKCGMALETIGVSATATATTYTCPMHPDVTQDSPGNCPKCGMALEGETSGGEQKNEELIDMSRRFWGCTALA
LPVFFLAMTADMLPGWLPNWLSLQMVQWIECALATPVVVWGGWPFFVRGWQSVRTWNLNMFTLIALGVSVSWSYSMVALL
LPGLFPTIMQMSDGLVPVYFEAAAMITTLVLLGQVLELRARSRTNAAIEMLLSLAPNTARIVREDGTEEDIPLDQVQSGA
TLRVRPGDKVPVDGTVIEGDSNIDESMVTGESLPVTKSAGEKLIGATVNGTGSLLMRAEKVGSDTLLAQIVDMVAKAQRT
RAPIQKLADLVAGYFVPAIVGCAVLTFAVWFGWGPEPRLAHAVVNAVAVLIIACPCALGLATPISIMVGTGRGATAGVLI
KNAEALEIMEKVDTLVVDKTGTLTEGKPKLVAVQAEEGFDEDQLVRLVASLERASEHPLAEAIVRGAEEKGIKLVKADNF
KSLTGKGVTGEVDGESVAAGNVALMESLGINVENLSQQADQQRAEGQTVMLIAINGKAAGLIGVADPIKESTAEAIRDLH
GEGIKIVMITGDNQITAKAVAGKLEIDQVHAEVLPEEKATLIKKLQAEGHIVAMAGDGINDAPALAQAHVGIAMGTGTDV
AIESASITLVKGDLRGIVRARRLSRATMRNIRQNLFFAFFYNSAGVPIAAGVLFPFFGILLSPMIAAAAMSFSSVSVISN
SLRLKRVKL
>Mature_808_residues
SAKLNKEQDQLNDPVCDMSVSHDSKHTYDYADKQYLFCSEHCLKKFKEQPEQYLDKETSPPSKTEGESKTYTCPMHPEIQ
QHDPGTCPKCGMALETIGVSATATATTYTCPMHPDVTQDSPGNCPKCGMALEGETSGGEQKNEELIDMSRRFWGCTALAL
PVFFLAMTADMLPGWLPNWLSLQMVQWIECALATPVVVWGGWPFFVRGWQSVRTWNLNMFTLIALGVSVSWSYSMVALLL
PGLFPTIMQMSDGLVPVYFEAAAMITTLVLLGQVLELRARSRTNAAIEMLLSLAPNTARIVREDGTEEDIPLDQVQSGAT
LRVRPGDKVPVDGTVIEGDSNIDESMVTGESLPVTKSAGEKLIGATVNGTGSLLMRAEKVGSDTLLAQIVDMVAKAQRTR
APIQKLADLVAGYFVPAIVGCAVLTFAVWFGWGPEPRLAHAVVNAVAVLIIACPCALGLATPISIMVGTGRGATAGVLIK
NAEALEIMEKVDTLVVDKTGTLTEGKPKLVAVQAEEGFDEDQLVRLVASLERASEHPLAEAIVRGAEEKGIKLVKADNFK
SLTGKGVTGEVDGESVAAGNVALMESLGINVENLSQQADQQRAEGQTVMLIAINGKAAGLIGVADPIKESTAEAIRDLHG
EGIKIVMITGDNQITAKAVAGKLEIDQVHAEVLPEEKATLIKKLQAEGHIVAMAGDGINDAPALAQAHVGIAMGTGTDVA
IESASITLVKGDLRGIVRARRLSRATMRNIRQNLFFAFFYNSAGVPIAAGVLFPFFGILLSPMIAAAAMSFSSVSVISNS
LRLKRVKL

Specific function: Component of the sil cation-efflux system that confers resistance to silver [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=706, Percent_Identity=37.1104815864023, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI115529486, Length=696, Percent_Identity=36.3505747126437, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI55743073, Length=548, Percent_Identity=37.956204379562, Blast_Score=340, Evalue=3e-93,
Organism=Homo sapiens, GI48762687, Length=272, Percent_Identity=31.9852941176471, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI48762689, Length=272, Percent_Identity=31.9852941176471, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI48762691, Length=272, Percent_Identity=31.9852941176471, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI48762685, Length=272, Percent_Identity=31.9852941176471, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI28373109, Length=174, Percent_Identity=33.9080459770115, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI28373115, Length=174, Percent_Identity=33.9080459770115, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI28373111, Length=174, Percent_Identity=33.9080459770115, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI28373107, Length=174, Percent_Identity=33.9080459770115, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI28373113, Length=174, Percent_Identity=33.9080459770115, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI28373103, Length=174, Percent_Identity=33.9080459770115, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI28373105, Length=174, Percent_Identity=33.9080459770115, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI118498343, Length=166, Percent_Identity=38.5542168674699, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI24638454, Length=180, Percent_Identity=31.6666666666667, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI209413709, Length=181, Percent_Identity=32.0441988950276, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4502285, Length=181, Percent_Identity=32.0441988950276, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI27886529, Length=175, Percent_Identity=32, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI10835220, Length=174, Percent_Identity=31.6091954022989, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI310128958, Length=159, Percent_Identity=32.7044025157233, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI153946397, Length=217, Percent_Identity=28.110599078341, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI22748667, Length=240, Percent_Identity=24.5833333333333, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI297374799, Length=238, Percent_Identity=24.3697478991597, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI83700225, Length=238, Percent_Identity=24.3697478991597, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI51944966, Length=263, Percent_Identity=24.3346007604563, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI4502271, Length=260, Percent_Identity=24.2307692307692, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI237681109, Length=260, Percent_Identity=22.3076923076923, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI21361181, Length=260, Percent_Identity=22.3076923076923, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI237681111, Length=260, Percent_Identity=22.3076923076923, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI1786691, Length=683, Percent_Identity=45.3879941434846, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI1789879, Length=633, Percent_Identity=33.4913112164297, Blast_Score=283, Evalue=4e-77,
Organism=Escherichia coli, GI1786914, Length=484, Percent_Identity=32.4380165289256, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI2367363, Length=634, Percent_Identity=24.1324921135647, Blast_Score=135, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17556548, Length=680, Percent_Identity=37.9411764705882, Blast_Score=397, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI193210130, Length=174, Percent_Identity=31.6091954022989, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17554158, Length=174, Percent_Identity=31.6091954022989, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988506, Length=174, Percent_Identity=31.6091954022989, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71997275, Length=186, Percent_Identity=32.7956989247312, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997262, Length=186, Percent_Identity=32.7956989247312, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559224, Length=222, Percent_Identity=26.5765765765766, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17557486, Length=291, Percent_Identity=26.1168384879725, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71997269, Length=166, Percent_Identity=33.1325301204819, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557770, Length=211, Percent_Identity=27.4881516587678, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI32566766, Length=211, Percent_Identity=27.4881516587678, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193203356, Length=181, Percent_Identity=29.8342541436464, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203354, Length=181, Percent_Identity=29.8342541436464, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531459, Length=182, Percent_Identity=30.2197802197802, Blast_Score=73, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320475, Length=641, Percent_Identity=37.1294851794072, Blast_Score=366, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6319772, Length=648, Percent_Identity=30.5555555555556, Blast_Score=303, Evalue=6e-83,
Organism=Saccharomyces cerevisiae, GI6325221, Length=568, Percent_Identity=25.1760563380282, Blast_Score=134, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6321430, Length=553, Percent_Identity=24.5931283905967, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321271, Length=181, Percent_Identity=32.5966850828729, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6321432, Length=180, Percent_Identity=32.7777777777778, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320245, Length=287, Percent_Identity=28.2229965156794, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320243, Length=287, Percent_Identity=28.2229965156794, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320244, Length=287, Percent_Identity=28.2229965156794, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221329854, Length=491, Percent_Identity=36.4562118126273, Blast_Score=249, Evalue=7e-66,
Organism=Drosophila melanogaster, GI161085803, Length=166, Percent_Identity=35.5421686746988, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281366617, Length=166, Percent_Identity=35.5421686746988, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668708, Length=166, Percent_Identity=35.5421686746988, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668696, Length=166, Percent_Identity=35.5421686746988, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668704, Length=166, Percent_Identity=35.5421686746988, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24762455, Length=175, Percent_Identity=30.8571428571429, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24762453, Length=175, Percent_Identity=30.8571428571429, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24762447, Length=175, Percent_Identity=30.8571428571429, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24762457, Length=175, Percent_Identity=30.8571428571429, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24762449, Length=175, Percent_Identity=30.8571428571429, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24762445, Length=175, Percent_Identity=30.8571428571429, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24762451, Length=175, Percent_Identity=30.8571428571429, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17136664, Length=180, Percent_Identity=30.5555555555556, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281366676, Length=255, Percent_Identity=24.7058823529412, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45553441, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648580, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648578, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553435, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553439, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362164, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648576, Length=258, Percent_Identity=23.2558139534884, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553437, Length=258, Percent_Identity=23.2558139534884, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648582, Length=258, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR007029 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase; PF04945 YHS [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 86500; Mature: 86369

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKLNKEQDQLNDPVCDMSVSHDSKHTYDYADKQYLFCSEHCLKKFKEQPEQYLDKETS
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHCCCCC
PPSKTEGESKTYTCPMHPEIQQHDPGTCPKCGMALETIGVSATATATTYTCPMHPDVTQD
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECEEEEECCCCCCCCCC
SPGNCPKCGMALEGETSGGEQKNEELIDMSRRFWGCTALALPVFFLAMTADMLPGWLPNW
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LSLQMVQWIECALATPVVVWGGWPFFVRGWQSVRTWNLNMFTLIALGVSVSWSYSMVALL
HHHHHHHHHHHHHCCCEEEECCCHHHHHCHHHHEEECCHHHHHHHHHCCCCCHHHHHHHH
LPGLFPTIMQMSDGLVPVYFEAAAMITTLVLLGQVLELRARSRTNAAIEMLLSLAPNTAR
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHH
IVREDGTEEDIPLDQVQSGATLRVRPGDKVPVDGTVIEGDSNIDESMVTGESLPVTKSAG
HEECCCCCCCCCHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCHHHHCCCCCCCCHHCC
EKLIGATVNGTGSLLMRAEKVGSDTLLAQIVDMVAKAQRTRAPIQKLADLVAGYFVPAIV
CCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCAVLTFAVWFGWGPEPRLAHAVVNAVAVLIIACPCALGLATPISIMVGTGRGATAGVLI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
KNAEALEIMEKVDTLVVDKTGTLTEGKPKLVAVQAEEGFDEDQLVRLVASLERASEHPLA
ECHHHHHHHHHHHHEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHH
EAIVRGAEEKGIKLVKADNFKSLTGKGVTGEVDGESVAAGNVALMESLGINVENLSQQAD
HHHHCCCHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHH
QQRAEGQTVMLIAINGKAAGLIGVADPIKESTAEAIRDLHGEGIKIVMITGDNQITAKAV
HHHHCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEHHHH
AGKLEIDQVHAEVLPEEKATLIKKLQAEGHIVAMAGDGINDAPALAQAHVGIAMGTGTDV
HCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCEEEECCCCCE
AIESASITLVKGDLRGIVRARRLSRATMRNIRQNLFFAFFYNSAGVPIAAGVLFPFFGIL
EEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHH
LSPMIAAAAMSFSSVSVISNSLRLKRVKL
HHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
SAKLNKEQDQLNDPVCDMSVSHDSKHTYDYADKQYLFCSEHCLKKFKEQPEQYLDKETS
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHCCCCC
PPSKTEGESKTYTCPMHPEIQQHDPGTCPKCGMALETIGVSATATATTYTCPMHPDVTQD
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECEEEEECCCCCCCCCC
SPGNCPKCGMALEGETSGGEQKNEELIDMSRRFWGCTALALPVFFLAMTADMLPGWLPNW
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LSLQMVQWIECALATPVVVWGGWPFFVRGWQSVRTWNLNMFTLIALGVSVSWSYSMVALL
HHHHHHHHHHHHHCCCEEEECCCHHHHHCHHHHEEECCHHHHHHHHHCCCCCHHHHHHHH
LPGLFPTIMQMSDGLVPVYFEAAAMITTLVLLGQVLELRARSRTNAAIEMLLSLAPNTAR
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHH
IVREDGTEEDIPLDQVQSGATLRVRPGDKVPVDGTVIEGDSNIDESMVTGESLPVTKSAG
HEECCCCCCCCCHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCHHHHCCCCCCCCHHCC
EKLIGATVNGTGSLLMRAEKVGSDTLLAQIVDMVAKAQRTRAPIQKLADLVAGYFVPAIV
CCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCAVLTFAVWFGWGPEPRLAHAVVNAVAVLIIACPCALGLATPISIMVGTGRGATAGVLI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
KNAEALEIMEKVDTLVVDKTGTLTEGKPKLVAVQAEEGFDEDQLVRLVASLERASEHPLA
ECHHHHHHHHHHHHEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHH
EAIVRGAEEKGIKLVKADNFKSLTGKGVTGEVDGESVAAGNVALMESLGINVENLSQQAD
HHHHCCCHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHH
QQRAEGQTVMLIAINGKAAGLIGVADPIKESTAEAIRDLHGEGIKIVMITGDNQITAKAV
HHHHCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEHHHH
AGKLEIDQVHAEVLPEEKATLIKKLQAEGHIVAMAGDGINDAPALAQAHVGIAMGTGTDV
HCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCEEEECCCCCE
AIESASITLVKGDLRGIVRARRLSRATMRNIRQNLFFAFFYNSAGVPIAAGVLFPFFGIL
EEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHH
LSPMIAAAAMSFSSVSVISNSLRLKRVKL
HHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]