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The map label for this gene is pabB [H]

Identifier: 119945665

GI number: 119945665

Start: 2407212

End: 2408636

Strand: Direct

Name: pabB [H]

Synonym: Ping_1978

Alternate gene names: 119945665

Gene position: 2407212-2408636 (Clockwise)

Preceding gene: 119945660

Following gene: 119945667

Centisome position: 52.79

GC content: 40.07

Gene sequence:

>1425_bases
ATGACTAATGCTAATTCCACTATATTAATACAGCCTATCTTATTAACCATTGCTGAACTTACCAATATAAAAGCGCAGAT
AGCAGGCTTAGATTGGGCAGTTTTACTTGAATCAGCCGGGACGGATCATGTTGATAGCAGGTGGTCGATTATTAGTGCAC
AGCCCGTTGCTAATATGGTGACATATCAAGGGATCAGCACCATAACACAGGGCAACAAAACTATCAGTGATTCTTCTGAT
CCACTTGCCTTGCAACAAAACCTGCGCCAAAAATTATTTCATGATAGTAGCAATGATAATACCATAGAGACTGAGGTTCC
CTTTACCGGCGGCGTATTAGGTTATTATTCCTATGGACTGGGGAATTATTTTGAGAATATCAAAAATGCTGATAAACCGG
TCACGCTTGAGTTGCCTGAAATGGCGGTGGGTTTTTATGACTGGGCCTTGCTTATTGATAATAAAAATGAACAAAATTAT
TTAGTTGTCCATAAAATCAAACAGTGCAGCGCAAGCCTGCAGTCATTATGGCAACAAAGATTTGATTGGTTAAAAGCGCA
AAATTTAAAAGCAAACAACGAAAATTTTAAATTATCCTCATCCTGGCAGGCAAATATGAGCAAATCACAATATGCACATA
AATTTGCGAAAATACAGGAATATATACTCGCGGGCGATTGCTATCAGGTTAATCTAACGCAACGATTTAAAGCAAGTTAC
CAGGGTGACGAATATCAGGCTTACCAAGCTTTGCTGGCAGAGAACCGCCCGCCTTTTGCTGCCTTTATGCGTTTACCCGA
ACAAGCAATTATCTCACTGTCCCCTGAACGCTTTATAAAATTGCATAATAATATTGTAGAAACTAAACCCATCAAAGGTA
CAACCCCCCGTTTTAATGATTTTTTAAGGGATCAAATAAGTAAACAAACCTTATTAGACTCTGAAAAAGATCGCTCAGAA
AACTTAATGATAGTGGATCTTCTGCGCAACGATATTGGCCGAGTGTGTACTGCTGGCAGTGTCTCTGTGCCGACGCTGTT
TGACATCGAAAGTTTTCCAGCCGTGCACCATTTAGTTAGCACAGTAACAGGTCAATTGGACAGACTTTATAGCAGTGAAG
ATTTATTACGCGCATGCTTTCCCGGTGGCTCAATTACCGGTGCGCCTAAAATACGTGCGATGGAAATAATAGCCGAATTA
GAACCACATAACAGACAAGTTTATTGTGGCAGCATTGGTTATGTTAATGGCAATGGGCGAACAGATACCAATATTGCCAT
TAGAACCTTGCTCTGTTATCAGGGGGCTATTTATTGTTGGGCAGGAGGCGGTTTAGTCGCTGATTCCAATGTTGATGCTG
AATATCAGGAGTGTTTTGACAAGGTAAGTAAAATTTTACCCTGTCTGGAAATTTTGAACAAATAA

Upstream 100 bases:

>100_bases
AGGGTATAAAGGGCTGATATATAGTACAGAGAATGTTAATCTGTAAATACATATCCACCAAAACATTTGTTACAAAACTG
TTGACTGAATTCTAAAAAAT

Downstream 100 bases:

>100_bases
AGCTTCGAGCCTTCGGGCTTTCGGGCTTCGAGCTTCGAGCTTCGAGCTTCGAGCTTTAATCAGCGCACAGGCAGTTCAAT
ATCTTTAAATAATTGACTGA

Product: para-aminobenzoate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTNANSTILIQPILLTIAELTNIKAQIAGLDWAVLLESAGTDHVDSRWSIISAQPVANMVTYQGISTITQGNKTISDSSD
PLALQQNLRQKLFHDSSNDNTIETEVPFTGGVLGYYSYGLGNYFENIKNADKPVTLELPEMAVGFYDWALLIDNKNEQNY
LVVHKIKQCSASLQSLWQQRFDWLKAQNLKANNENFKLSSSWQANMSKSQYAHKFAKIQEYILAGDCYQVNLTQRFKASY
QGDEYQAYQALLAENRPPFAAFMRLPEQAIISLSPERFIKLHNNIVETKPIKGTTPRFNDFLRDQISKQTLLDSEKDRSE
NLMIVDLLRNDIGRVCTAGSVSVPTLFDIESFPAVHHLVSTVTGQLDRLYSSEDLLRACFPGGSITGAPKIRAMEIIAEL
EPHNRQVYCGSIGYVNGNGRTDTNIAIRTLLCYQGAIYCWAGGGLVADSNVDAEYQECFDKVSKILPCLEILNK

Sequences:

>Translated_474_residues
MTNANSTILIQPILLTIAELTNIKAQIAGLDWAVLLESAGTDHVDSRWSIISAQPVANMVTYQGISTITQGNKTISDSSD
PLALQQNLRQKLFHDSSNDNTIETEVPFTGGVLGYYSYGLGNYFENIKNADKPVTLELPEMAVGFYDWALLIDNKNEQNY
LVVHKIKQCSASLQSLWQQRFDWLKAQNLKANNENFKLSSSWQANMSKSQYAHKFAKIQEYILAGDCYQVNLTQRFKASY
QGDEYQAYQALLAENRPPFAAFMRLPEQAIISLSPERFIKLHNNIVETKPIKGTTPRFNDFLRDQISKQTLLDSEKDRSE
NLMIVDLLRNDIGRVCTAGSVSVPTLFDIESFPAVHHLVSTVTGQLDRLYSSEDLLRACFPGGSITGAPKIRAMEIIAEL
EPHNRQVYCGSIGYVNGNGRTDTNIAIRTLLCYQGAIYCWAGGGLVADSNVDAEYQECFDKVSKILPCLEILNK
>Mature_473_residues
TNANSTILIQPILLTIAELTNIKAQIAGLDWAVLLESAGTDHVDSRWSIISAQPVANMVTYQGISTITQGNKTISDSSDP
LALQQNLRQKLFHDSSNDNTIETEVPFTGGVLGYYSYGLGNYFENIKNADKPVTLELPEMAVGFYDWALLIDNKNEQNYL
VVHKIKQCSASLQSLWQQRFDWLKAQNLKANNENFKLSSSWQANMSKSQYAHKFAKIQEYILAGDCYQVNLTQRFKASYQ
GDEYQAYQALLAENRPPFAAFMRLPEQAIISLSPERFIKLHNNIVETKPIKGTTPRFNDFLRDQISKQTLLDSEKDRSEN
LMIVDLLRNDIGRVCTAGSVSVPTLFDIESFPAVHHLVSTVTGQLDRLYSSEDLLRACFPGGSITGAPKIRAMEIIAELE
PHNRQVYCGSIGYVNGNGRTDTNIAIRTLLCYQGAIYCWAGGGLVADSNVDAEYQECFDKVSKILPCLEILNK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=448, Percent_Identity=49.7767857142857, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1787518, Length=376, Percent_Identity=30.5851063829787, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786809, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082077, Length=208, Percent_Identity=24.5192307692308, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=484, Percent_Identity=31.404958677686, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=404, Percent_Identity=29.2079207920792, Blast_Score=142, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 53023; Mature: 52891

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNANSTILIQPILLTIAELTNIKAQIAGLDWAVLLESAGTDHVDSRWSIISAQPVANMV
CCCCCCEEEEHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCCCCCCEEEEECCHHHHHH
TYQGISTITQGNKTISDSSDPLALQQNLRQKLFHDSSNDNTIETEVPFTGGVLGYYSYGL
HHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHH
GNYFENIKNADKPVTLELPEMAVGFYDWALLIDNKNEQNYLVVHKIKQCSASLQSLWQQR
HHHHHHHCCCCCCEEEECCHHHHCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHH
FDWLKAQNLKANNENFKLSSSWQANMSKSQYAHKFAKIQEYILAGDCYQVNLTQRFKASY
HHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCC
QGDEYQAYQALLAENRPPFAAFMRLPEQAIISLSPERFIKLHNNIVETKPIKGTTPRFND
CCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
FLRDQISKQTLLDSEKDRSENLMIVDLLRNDIGRVCTAGSVSVPTLFDIESFPAVHHLVS
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHH
TVTGQLDRLYSSEDLLRACFPGGSITGAPKIRAMEIIAELEPHNRQVYCGSIGYVNGNGR
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCC
TDTNIAIRTLLCYQGAIYCWAGGGLVADSNVDAEYQECFDKVSKILPCLEILNK
CCCHHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNANSTILIQPILLTIAELTNIKAQIAGLDWAVLLESAGTDHVDSRWSIISAQPVANMV
CCCCCEEEEHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCCCCCCEEEEECCHHHHHH
TYQGISTITQGNKTISDSSDPLALQQNLRQKLFHDSSNDNTIETEVPFTGGVLGYYSYGL
HHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHH
GNYFENIKNADKPVTLELPEMAVGFYDWALLIDNKNEQNYLVVHKIKQCSASLQSLWQQR
HHHHHHHCCCCCCEEEECCHHHHCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHH
FDWLKAQNLKANNENFKLSSSWQANMSKSQYAHKFAKIQEYILAGDCYQVNLTQRFKASY
HHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCC
QGDEYQAYQALLAENRPPFAAFMRLPEQAIISLSPERFIKLHNNIVETKPIKGTTPRFND
CCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHH
FLRDQISKQTLLDSEKDRSENLMIVDLLRNDIGRVCTAGSVSVPTLFDIESFPAVHHLVS
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHH
TVTGQLDRLYSSEDLLRACFPGGSITGAPKIRAMEIIAELEPHNRQVYCGSIGYVNGNGR
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCC
TDTNIAIRTLLCYQGAIYCWAGGGLVADSNVDAEYQECFDKVSKILPCLEILNK
CCCHHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]