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The map label for this gene is iorA [H]

Identifier: 119945527

GI number: 119945527

Start: 2220025

End: 2220492

Strand: Direct

Name: iorA [H]

Synonym: Ping_1831

Alternate gene names: 119945527

Gene position: 2220025-2220492 (Clockwise)

Preceding gene: 119945526

Following gene: 119945528

Centisome position: 48.69

GC content: 45.09

Gene sequence:

>468_bases
ATGGCAAAATTTATTTTAAACGGCGAGCCGATGACTGCCGACGTAGAGAGCGATACTCCTCTACTGTGGGTCATTCGTGA
CGAACTCAACATGACGGGTACCAAATTTGGTTGCGGTATTGGAACCTGTGGAGCCTGTACTGTCCATGTGGGCGGACGTG
CAACACGTTCATGTATTACTCCCATTTCGATAGTAGAAGGGGCTGAAATTACTACCATTGAAGGTTTGTCAGAAAAAGGC
GACCATCCATTACAAATTTCATGGATAAACTTGCAGGTGCCACAATGTGGTTACTGCCAGTCGGGTCAAATTATGCAAGC
TGCTGCATTATTAAAAGACATTCCTAAACCGACGGATAAAGATATTGACGCTGTGATGGCTGGGAACTTATGTCGTTGTA
TGACTTACGTGCGTATCCGTAGTGCTATTCATGAAGCGGCAAATGCCATTGAAGGAGAGCAATCATGA

Upstream 100 bases:

>100_bases
CAAACTGCAGGGGAAAACATCTGGCCTAAATTACAACAACAAGTGGGCGAGATCCGTAATCAACCCCGATTTGAGCAATA
ACTTCACTGGAGAAGTGCCA

Downstream 100 bases:

>100_bases
GCAGACTTCCTAAACGTGGTTCACAGGGTATAACCCGACGCGGCTTTTTAATTGGTATGACAGCGGTTGGTGTCAGCTTT
GGTTTCCCTCGTCACTTGAT

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MAKFILNGEPMTADVESDTPLLWVIRDELNMTGTKFGCGIGTCGACTVHVGGRATRSCITPISIVEGAEITTIEGLSEKG
DHPLQISWINLQVPQCGYCQSGQIMQAAALLKDIPKPTDKDIDAVMAGNLCRCMTYVRIRSAIHEAANAIEGEQS

Sequences:

>Translated_155_residues
MAKFILNGEPMTADVESDTPLLWVIRDELNMTGTKFGCGIGTCGACTVHVGGRATRSCITPISIVEGAEITTIEGLSEKG
DHPLQISWINLQVPQCGYCQSGQIMQAAALLKDIPKPTDKDIDAVMAGNLCRCMTYVRIRSAIHEAANAIEGEQS
>Mature_154_residues
AKFILNGEPMTADVESDTPLLWVIRDELNMTGTKFGCGIGTCGACTVHVGGRATRSCITPISIVEGAEITTIEGLSEKGD
HPLQISWINLQVPQCGYCQSGQIMQAAALLKDIPKPTDKDIDAVMAGNLCRCMTYVRIRSAIHEAANAIEGEQS

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=146, Percent_Identity=34.2465753424658, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=32.8947368421053, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=41.9753086419753, Blast_Score=119, Evalue=8e-29,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=38.2978723404255, Blast_Score=82, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=36.5384615384615, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=33.9869281045752, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=33.9869281045752, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17737937, Length=146, Percent_Identity=34.9315068493151, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=35.4037267080745, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=35.4037267080745, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=34.1935483870968, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=33.1168831168831, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24647193, Length=155, Percent_Identity=34.1935483870968, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16596; Mature: 16465

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFILNGEPMTADVESDTPLLWVIRDELNMTGTKFGCGIGTCGACTVHVGGRATRSCIT
CCEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCC
PISIVEGAEITTIEGLSEKGDHPLQISWINLQVPQCGYCQSGQIMQAAALLKDIPKPTDK
CHHEECCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCC
DIDAVMAGNLCRCMTYVRIRSAIHEAANAIEGEQS
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKFILNGEPMTADVESDTPLLWVIRDELNMTGTKFGCGIGTCGACTVHVGGRATRSCIT
CEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCC
PISIVEGAEITTIEGLSEKGDHPLQISWINLQVPQCGYCQSGQIMQAAALLKDIPKPTDK
CHHEECCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCC
DIDAVMAGNLCRCMTYVRIRSAIHEAANAIEGEQS
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]