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The map label for this gene is xdhA [C]

Identifier: 119945528

GI number: 119945528

Start: 2220489

End: 2222792

Strand: Direct

Name: xdhA [C]

Synonym: Ping_1832

Alternate gene names: 119945528

Gene position: 2220489-2222792 (Clockwise)

Preceding gene: 119945527

Following gene: 119945532

Centisome position: 48.7

GC content: 47.96

Gene sequence:

>2304_bases
ATGAGCAGACTTCCTAAACGTGGTTCACAGGGTATAACCCGACGCGGCTTTTTAATTGGTATGACAGCGGTTGGTGTCAG
CTTTGGTTTCCCTCGTCACTTGATGGCGGCAATGGATCCTGCCAGCCCTAACGGTAAAGTATTACCGAGCGAAGGTGATA
TTTACGAGCCTTCATTGTGGTACTCAATCGATACCGCCGGCAAAATTAAAGTCAACATTATGCGCTCAGAAATGGGCCAA
CATGTCGGTACCGCTATTGCGCGTATTCTTGCTGATGAACTAGAAGCCTCTTGGGACGACATTGAAATTATTCATGTTGA
CAGTGACCCACGCTGGGGTTACATGGTTACCGGTGGCAGTTGGTCTATTTCACAAAGCTGGCCGGTATATCGTCAAGCTG
GAGCTGCTGGTCGCACCGCCTTCATCGAAGCCGCGGCCAAAAAATGGGGCATTAAAGCACAAGATTGTGAAGCTAAAAAC
GGTAAAATCATATCCAGTAAAGGTGAGTTATCGTACGGTGAATTAGTTACCTTGGGCTTAACCCGTCAGTTTACGGAAGA
AGAACTGAAACAACTGCCGCTGAAGCCAAATGCCGATCTTACACTTGTTGGTCAACCGGTGACCTCTCTTGATATCGCCA
ACAAGACCAACGGTAAAACAATATATGGTATCGACGCTAAAGTTGATGGCATGGTATACGCCAATCCTATTTTACCGCCC
ACCCGTTATGGCTCTAAAGTCGTGACATTTGATGATTCAGCTGCGAAAGCAATTAAAGGTTATCAGAAAACGATTGTATT
AGAGGATGCGAGTGGCAGTGTCCCAGGTTGGTTAATGGTTATCGCCAGCAGCTTTCATGCGGCTCAAAAAGCCTCGAAAT
TAGTGAAAGTGACATGGGATGTGGGTGAAACGGCAACAGTGTCTGAAGCCGATATTATTGAACACGGCAGAAAATTACTT
GGCGATAACACCAAAGGCAGTATTTTAGATACTGGTAATGTTGACACTGCACCCGTATTTGCGAGTGCCAGCAGCAGCAT
TGCACAAGAATATATCACCAGCACAGTATTACATGCGCAAATGGAACCTGTTAATGCCTTGGTCTTTAAAAATCCAGACG
GCGTATGGGAAATCCATTCAGGTACTCAGTGGCAGTCACTTATCCTACCTGTATTAGCCATCGCATTAGGTGAAGACGAA
GCTAACATTGTTATGCGTAGCTACATGTTAGGTGGCGGCTTTGGCCGTAGGCTCAATGGCGATTACACCGTTCCAGCGGC
GTTGACTTCTAAAGCCTTAGGCGGAAAACCGGTTAAAATGGTGATGACGCGTCCACAAGACATGCTCTTTGATAGCGCGC
GCTCAGCTTCAGTTCAACAACTAAAAATGGCTTTTGATGATAAAAAAGCGGTTTCTGCGATGGAACATCATGCCACTGCC
GGTTGGCCAACCCAAGTATTAGCCCCTTTCTTTATGCCAAAAGGGGTGAATGGCGAACCCTATGATCCGTTTTCAATTTC
AGGGGCAGACCATTGGTATAGCGTTGGCGCCCAAAAAGTCCGCGCTGTGTCCAATGATCTCGCCATCGCCACCTTCAGGC
CGGGTTGGTTACGTTCAGTAGGGCCAGGCTGGACCAATTGGGCCGTTGAAAGCTTTATGGACGAAGCAGCGCATCACGCG
GGCAAAGATGCAGTGCAATTCCGTTTAGACATGCTGATTGCCGAAGGCCGAAATGCCGGTAGCACACCCGTTGCCGAAGG
TGGTGCAGCGCGTCAGGCCGCGGTACTGAAAAAAGCCGCTGAGATGATTGGTTGGGGCACACCACAAGCCAAAGATACCG
GGCTTGGAATTGCATCAACATTTGGCCAAGAACGTGATATGCCAACATGGGTATCGTGCGCGGTACAAGTTCATGTCGAC
AAAACCAACGGTATTGTCAATGTGCAAAAACTGGTTATCGCCATCGATGCCGGTATTATTGTTGATCCAAACGGCGCAGA
AGCGCAATGTCAGGGCGCGGCACTGTGGGGATTGTCCATGGCGTTATTTGAAGGCACCGAACTACTTAATGGTCAGTATA
AAGACTCAAACTTCGATACTTATACTCCGCTGCGTTTAAGTCAAGCGCCGGAAATTAAGATTGAGTTTATTGACAGTAAA
ATGCCACCGTCCGGATTAGGTGAACCAGCCGTTACTCCGGTTGCTCCAGCGATTGCTAATGCCATCTATCAAGCCGTGGG
CGTGCGGTTACGCAAAATCCCAATGAAACCAAGTGACTTAAAAAGTGCTTTGGCAAAAGCCTAA

Upstream 100 bases:

>100_bases
TTGACGCTGTGATGGCTGGGAACTTATGTCGTTGTATGACTTACGTGCGTATCCGTAGTGCTATTCATGAAGCGGCAAAT
GCCATTGAAGGAGAGCAATC

Downstream 100 bases:

>100_bases
TTCAACGCGTACTATAAAAAGCCCGATTTTTCGGGTTTTTTTATGTCAGTTTTTTATCTTCAGTATTTGATCTTAAACTG
TTATACCAAGCTAAATAAAT

Product: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding

Products: NA

Alternate protein names: ALDH [H]

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MSRLPKRGSQGITRRGFLIGMTAVGVSFGFPRHLMAAMDPASPNGKVLPSEGDIYEPSLWYSIDTAGKIKVNIMRSEMGQ
HVGTAIARILADELEASWDDIEIIHVDSDPRWGYMVTGGSWSISQSWPVYRQAGAAGRTAFIEAAAKKWGIKAQDCEAKN
GKIISSKGELSYGELVTLGLTRQFTEEELKQLPLKPNADLTLVGQPVTSLDIANKTNGKTIYGIDAKVDGMVYANPILPP
TRYGSKVVTFDDSAAKAIKGYQKTIVLEDASGSVPGWLMVIASSFHAAQKASKLVKVTWDVGETATVSEADIIEHGRKLL
GDNTKGSILDTGNVDTAPVFASASSSIAQEYITSTVLHAQMEPVNALVFKNPDGVWEIHSGTQWQSLILPVLAIALGEDE
ANIVMRSYMLGGGFGRRLNGDYTVPAALTSKALGGKPVKMVMTRPQDMLFDSARSASVQQLKMAFDDKKAVSAMEHHATA
GWPTQVLAPFFMPKGVNGEPYDPFSISGADHWYSVGAQKVRAVSNDLAIATFRPGWLRSVGPGWTNWAVESFMDEAAHHA
GKDAVQFRLDMLIAEGRNAGSTPVAEGGAARQAAVLKKAAEMIGWGTPQAKDTGLGIASTFGQERDMPTWVSCAVQVHVD
KTNGIVNVQKLVIAIDAGIIVDPNGAEAQCQGAALWGLSMALFEGTELLNGQYKDSNFDTYTPLRLSQAPEIKIEFIDSK
MPPSGLGEPAVTPVAPAIANAIYQAVGVRLRKIPMKPSDLKSALAKA

Sequences:

>Translated_767_residues
MSRLPKRGSQGITRRGFLIGMTAVGVSFGFPRHLMAAMDPASPNGKVLPSEGDIYEPSLWYSIDTAGKIKVNIMRSEMGQ
HVGTAIARILADELEASWDDIEIIHVDSDPRWGYMVTGGSWSISQSWPVYRQAGAAGRTAFIEAAAKKWGIKAQDCEAKN
GKIISSKGELSYGELVTLGLTRQFTEEELKQLPLKPNADLTLVGQPVTSLDIANKTNGKTIYGIDAKVDGMVYANPILPP
TRYGSKVVTFDDSAAKAIKGYQKTIVLEDASGSVPGWLMVIASSFHAAQKASKLVKVTWDVGETATVSEADIIEHGRKLL
GDNTKGSILDTGNVDTAPVFASASSSIAQEYITSTVLHAQMEPVNALVFKNPDGVWEIHSGTQWQSLILPVLAIALGEDE
ANIVMRSYMLGGGFGRRLNGDYTVPAALTSKALGGKPVKMVMTRPQDMLFDSARSASVQQLKMAFDDKKAVSAMEHHATA
GWPTQVLAPFFMPKGVNGEPYDPFSISGADHWYSVGAQKVRAVSNDLAIATFRPGWLRSVGPGWTNWAVESFMDEAAHHA
GKDAVQFRLDMLIAEGRNAGSTPVAEGGAARQAAVLKKAAEMIGWGTPQAKDTGLGIASTFGQERDMPTWVSCAVQVHVD
KTNGIVNVQKLVIAIDAGIIVDPNGAEAQCQGAALWGLSMALFEGTELLNGQYKDSNFDTYTPLRLSQAPEIKIEFIDSK
MPPSGLGEPAVTPVAPAIANAIYQAVGVRLRKIPMKPSDLKSALAKA
>Mature_766_residues
SRLPKRGSQGITRRGFLIGMTAVGVSFGFPRHLMAAMDPASPNGKVLPSEGDIYEPSLWYSIDTAGKIKVNIMRSEMGQH
VGTAIARILADELEASWDDIEIIHVDSDPRWGYMVTGGSWSISQSWPVYRQAGAAGRTAFIEAAAKKWGIKAQDCEAKNG
KIISSKGELSYGELVTLGLTRQFTEEELKQLPLKPNADLTLVGQPVTSLDIANKTNGKTIYGIDAKVDGMVYANPILPPT
RYGSKVVTFDDSAAKAIKGYQKTIVLEDASGSVPGWLMVIASSFHAAQKASKLVKVTWDVGETATVSEADIIEHGRKLLG
DNTKGSILDTGNVDTAPVFASASSSIAQEYITSTVLHAQMEPVNALVFKNPDGVWEIHSGTQWQSLILPVLAIALGEDEA
NIVMRSYMLGGGFGRRLNGDYTVPAALTSKALGGKPVKMVMTRPQDMLFDSARSASVQQLKMAFDDKKAVSAMEHHATAG
WPTQVLAPFFMPKGVNGEPYDPFSISGADHWYSVGAQKVRAVSNDLAIATFRPGWLRSVGPGWTNWAVESFMDEAAHHAG
KDAVQFRLDMLIAEGRNAGSTPVAEGGAARQAAVLKKAAEMIGWGTPQAKDTGLGIASTFGQERDMPTWVSCAVQVHVDK
TNGIVNVQKLVIAIDAGIIVDPNGAEAQCQGAALWGLSMALFEGTELLNGQYKDSNFDTYTPLRLSQAPEIKIEFIDSKM
PPSGLGEPAVTPVAPAIANAIYQAVGVRLRKIPMKPSDLKSALAKA

Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=494, Percent_Identity=24.2914979757085, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786478, Length=153, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737937, Length=307, Percent_Identity=25.0814332247557, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.3 [H]

Molecular weight: Translated: 82173; Mature: 82041

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLPKRGSQGITRRGFLIGMTAVGVSFGFPRHLMAAMDPASPNGKVLPSEGDIYEPSLW
CCCCCCCCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHCCCCCCCCCEECCCCCEECCCEE
YSIDTAGKIKVNIMRSEMGQHVGTAIARILADELEASWDDIEIIHVDSDPRWGYMVTGGS
EEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCC
WSISQSWPVYRQAGAAGRTAFIEAAAKKWGIKAQDCEAKNGKIISSKGELSYGELVTLGL
EECCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEEECH
TRQFTEEELKQLPLKPNADLTLVGQPVTSLDIANKTNGKTIYGIDAKVDGMVYANPILPP
HHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCCCCEEEEECCEECCEEEECCCCCC
TRYGSKVVTFDDSAAKAIKGYQKTIVLEDASGSVPGWLMVIASSFHAAQKASKLVKVTWD
CCCCCEEEEECCHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEC
VGETATVSEADIIEHGRKLLGDNTKGSILDTGNVDTAPVFASASSSIAQEYITSTVLHAQ
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHH
MEPVNALVFKNPDGVWEIHSGTQWQSLILPVLAIALGEDEANIVMRSYMLGGGFGRRLNG
CCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
DYTVPAALTSKALGGKPVKMVMTRPQDMLFDSARSASVQQLKMAFDDKKAVSAMEHHATA
CEEECHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
GWPTQVLAPFFMPKGVNGEPYDPFSISGADHWYSVGAQKVRAVSNDLAIATFRPGWLRSV
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHCC
GPGWTNWAVESFMDEAAHHAGKDAVQFRLDMLIAEGRNAGSTPVAEGGAARQAAVLKKAA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
EMIGWGTPQAKDTGLGIASTFGQERDMPTWVSCAVQVHVDKTNGIVNVQKLVIAIDAGII
HHHCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEEEEEECCEE
VDPNGAEAQCQGAALWGLSMALFEGTELLNGQYKDSNFDTYTPLRLSQAPEIKIEFIDSK
ECCCCCCCCCCCEEHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEECCCCCEEEEEECCC
MPPSGLGEPAVTPVAPAIANAIYQAVGVRLRKIPMKPSDLKSALAKA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
SRLPKRGSQGITRRGFLIGMTAVGVSFGFPRHLMAAMDPASPNGKVLPSEGDIYEPSLW
CCCCCCCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHCCCCCCCCCEECCCCCEECCCEE
YSIDTAGKIKVNIMRSEMGQHVGTAIARILADELEASWDDIEIIHVDSDPRWGYMVTGGS
EEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCC
WSISQSWPVYRQAGAAGRTAFIEAAAKKWGIKAQDCEAKNGKIISSKGELSYGELVTLGL
EECCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEEEECH
TRQFTEEELKQLPLKPNADLTLVGQPVTSLDIANKTNGKTIYGIDAKVDGMVYANPILPP
HHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCCCCEEEEECCEECCEEEECCCCCC
TRYGSKVVTFDDSAAKAIKGYQKTIVLEDASGSVPGWLMVIASSFHAAQKASKLVKVTWD
CCCCCEEEEECCHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEC
VGETATVSEADIIEHGRKLLGDNTKGSILDTGNVDTAPVFASASSSIAQEYITSTVLHAQ
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHH
MEPVNALVFKNPDGVWEIHSGTQWQSLILPVLAIALGEDEANIVMRSYMLGGGFGRRLNG
CCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
DYTVPAALTSKALGGKPVKMVMTRPQDMLFDSARSASVQQLKMAFDDKKAVSAMEHHATA
CEEECHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
GWPTQVLAPFFMPKGVNGEPYDPFSISGADHWYSVGAQKVRAVSNDLAIATFRPGWLRSV
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHCC
GPGWTNWAVESFMDEAAHHAGKDAVQFRLDMLIAEGRNAGSTPVAEGGAARQAAVLKKAA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
EMIGWGTPQAKDTGLGIASTFGQERDMPTWVSCAVQVHVDKTNGIVNVQKLVIAIDAGII
HHHCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEEEEEECCEE
VDPNGAEAQCQGAALWGLSMALFEGTELLNGQYKDSNFDTYTPLRLSQAPEIKIEFIDSK
ECCCCCCCCCCCEEHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEECCCCCEEEEEECCC
MPPSGLGEPAVTPVAPAIANAIYQAVGVRLRKIPMKPSDLKSALAKA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2606906 [H]