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The map label for this gene is guaD [H]

Identifier: 119945504

GI number: 119945504

Start: 2194062

End: 2194637

Strand: Direct

Name: guaD [H]

Synonym: Ping_1808

Alternate gene names: 119945504

Gene position: 2194062-2194637 (Clockwise)

Preceding gene: 119945501

Following gene: 119945506

Centisome position: 48.12

GC content: 43.23

Gene sequence:

>576_bases
ATGTTCTTGCAACCATCTGAAATTAGTTTTAAGTTACCTGGCTGGATAGACCTTTTTTCTCAACGCTATGTTTCAAGTAC
CGATCTAAATATACGCATGGCTTTTGTTATTTCAGCCGCGAAAAAGAATGTTGAGCAAGGGAGCGGGGGACCTTTTGCTG
CAGCTGTCTTTGAGATCGAAACAGGCAAACTGGTTTCCCTTGGTGTTAACTTAGTGACAACACAGGGTTTGTCTATTCTG
CATGCGGAAATAGTCGCGCTAGTCGCTGCTCAAAGGAAGCTTCGCACCTATGATCTCGCCATTACCCGGCATGAATTAGT
CACCAGCGCGGAGCCCTGTGCAATGTGCCTAGGCGCTATTTCATGGTCAGGAGTGTGCCATGTTGCAACAGCCGCGACAG
ATCAAGACGTAAGCGCTATTGGCTTTGATGAAGGCCCGAAACCAAACAATTGGATTAAATCCTTAAAGGCCAGAGGAATA
AAGGTGAGTACAAATATTCAACGAGAATTTTCCTGCTCAGTTTTACAGTTATATATTATAAATAATGGCTGTATTTATAA
TTCAGGGAAAAGTTAA

Upstream 100 bases:

>100_bases
ACTTAATGCGCTGTTGACTATCCTAAATAACAGGCGCTGGCAGAATCAACTAATTAGAGTCTTTTTCTGCGTCAGCTTAC
TACTTTCTTAGGAGAAAAAT

Downstream 100 bases:

>100_bases
TAAGTGCATTCAATCGTTCGTACTGACCTCGCGACTCATTTTTTCATGATCTGAAACCTGATCAATATTTAGAGTATTCC
AGAGCCTGACCGATAATCCA

Product: CMP/dCMP deaminase, zinc-binding

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MFLQPSEISFKLPGWIDLFSQRYVSSTDLNIRMAFVISAAKKNVEQGSGGPFAAAVFEIETGKLVSLGVNLVTTQGLSIL
HAEIVALVAAQRKLRTYDLAITRHELVTSAEPCAMCLGAISWSGVCHVATAATDQDVSAIGFDEGPKPNNWIKSLKARGI
KVSTNIQREFSCSVLQLYIINNGCIYNSGKS

Sequences:

>Translated_191_residues
MFLQPSEISFKLPGWIDLFSQRYVSSTDLNIRMAFVISAAKKNVEQGSGGPFAAAVFEIETGKLVSLGVNLVTTQGLSIL
HAEIVALVAAQRKLRTYDLAITRHELVTSAEPCAMCLGAISWSGVCHVATAATDQDVSAIGFDEGPKPNNWIKSLKARGI
KVSTNIQREFSCSVLQLYIINNGCIYNSGKS
>Mature_191_residues
MFLQPSEISFKLPGWIDLFSQRYVSSTDLNIRMAFVISAAKKNVEQGSGGPFAAAVFEIETGKLVSLGVNLVTTQGLSIL
HAEIVALVAAQRKLRTYDLAITRHELVTSAEPCAMCLGAISWSGVCHVATAATDQDVSAIGFDEGPKPNNWIKSLKARGI
KVSTNIQREFSCSVLQLYIINNGCIYNSGKS

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17554608, Length=110, Percent_Identity=38.1818181818182, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=113, Percent_Identity=38.9380530973451, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 20626; Mature: 20626

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLQPSEISFKLPGWIDLFSQRYVSSTDLNIRMAFVISAAKKNVEQGSGGPFAAAVFEIE
CCCCCCCCCEECCCHHHHHHHHHCCCCCCEEEEEEEEEHHHHCCCCCCCCCEEEEEEEEC
TGKLVSLGVNLVTTQGLSILHAEIVALVAAQRKLRTYDLAITRHELVTSAEPCAMCLGAI
CCCEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHCCCCHHHHHHHHC
SWSGVCHVATAATDQDVSAIGFDEGPKPNNWIKSLKARGIKVSTNIQREFSCSVLQLYII
CCCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCEEEEEEEE
NNGCIYNSGKS
ECCEEECCCCC
>Mature Secondary Structure
MFLQPSEISFKLPGWIDLFSQRYVSSTDLNIRMAFVISAAKKNVEQGSGGPFAAAVFEIE
CCCCCCCCCEECCCHHHHHHHHHCCCCCCEEEEEEEEEHHHHCCCCCCCCCEEEEEEEEC
TGKLVSLGVNLVTTQGLSILHAEIVALVAAQRKLRTYDLAITRHELVTSAEPCAMCLGAI
CCCEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHCCCCHHHHHHHHC
SWSGVCHVATAATDQDVSAIGFDEGPKPNNWIKSLKARGIKVSTNIQREFSCSVLQLYII
CCCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCEEEEEEEE
NNGCIYNSGKS
ECCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]