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The map label for this gene is lacA [H]

Identifier: 119945434

GI number: 119945434

Start: 2106469

End: 2107065

Strand: Direct

Name: lacA [H]

Synonym: Ping_1731

Alternate gene names: 119945434

Gene position: 2106469-2107065 (Clockwise)

Preceding gene: 119945433

Following gene: 119945435

Centisome position: 46.2

GC content: 39.7

Gene sequence:

>597_bases
ATGAAAGACAAAATGCATCATCAAAAAGTATATTTTTGTGATGATCAGGCGCTCGTTTCGGAGCAAATGCAATGTTTGGA
AACACTTTATGACTTTAATTTTACCCGGCCTACTGAAGTAAAAAAGAGAGAAATTCTTCTTTCCAAGTTATTTGCTGAAA
TAGGAGATAATTGTTATATCGAGCCACCACTCCATGCTAACTGGGGCAAGCATACACATTTAGGTGACAACGTTTATGCA
AATTTTAATTTGACCTTAGTCGATGATACTCATATATATATTGGTCATTATGTAATGATTGGACCTAACGTCACCATCGC
AACCGCGGGCCATCCCATTGACCCAGAACGACGGAAAAAAGCCGCGCAGTTTAATATTCCAGTCTATATTGGTAATAATG
TCTGGATCGGCGCAAATTGTGTCATTTTACCGGGCGTGACTATTGGTGAGAACAGTGTCATTGGAGCCGGCAGTATAGTA
ACAAAAAATATCCCTGCAAACGTCATCGCCGTCGGTAATCCGTGCCGTATTCTGCGTGAAATTAATGACCGGGACAAAGA
GTATTATTATAAAAATCTGAGGTTCGATGGTGAATAA

Upstream 100 bases:

>100_bases
GTAAGCCTGCCTAACAATAACAATCTAATTATTTTCTCCTTTCTGATTTTGCCGGGAGATTAAGCTAAATTTTAATAGAG
ATATTATGGGAATAATGAAC

Downstream 100 bases:

>100_bases
AAAAGCGGCATTGACAGCGGCAGGTTATTAGCCTGTATTAATCGTTTAATCAAGGGTTAGCTAATATGCTCATAATAAAG
ACACTTAATGGTTTTTACTC

Product: galactoside O-acetyltransferase

Products: NA

Alternate protein names: GAT; Thiogalactoside acetyltransferase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKDKMHHQKVYFCDDQALVSEQMQCLETLYDFNFTRPTEVKKREILLSKLFAEIGDNCYIEPPLHANWGKHTHLGDNVYA
NFNLTLVDDTHIYIGHYVMIGPNVTIATAGHPIDPERRKKAAQFNIPVYIGNNVWIGANCVILPGVTIGENSVIGAGSIV
TKNIPANVIAVGNPCRILREINDRDKEYYYKNLRFDGE

Sequences:

>Translated_198_residues
MKDKMHHQKVYFCDDQALVSEQMQCLETLYDFNFTRPTEVKKREILLSKLFAEIGDNCYIEPPLHANWGKHTHLGDNVYA
NFNLTLVDDTHIYIGHYVMIGPNVTIATAGHPIDPERRKKAAQFNIPVYIGNNVWIGANCVILPGVTIGENSVIGAGSIV
TKNIPANVIAVGNPCRILREINDRDKEYYYKNLRFDGE
>Mature_198_residues
MKDKMHHQKVYFCDDQALVSEQMQCLETLYDFNFTRPTEVKKREILLSKLFAEIGDNCYIEPPLHANWGKHTHLGDNVYA
NFNLTLVDDTHIYIGHYVMIGPNVTIATAGHPIDPERRKKAAQFNIPVYIGNNVWIGANCVILPGVTIGENSVIGAGSIV
TKNIPANVIAVGNPCRILREINDRDKEYYYKNLRFDGE

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=198, Percent_Identity=48.989898989899, Blast_Score=216, Evalue=7e-58,
Organism=Escherichia coli, GI1786664, Length=180, Percent_Identity=40, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1788367, Length=152, Percent_Identity=30.2631578947368, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788345, Length=178, Percent_Identity=27.5280898876405, Blast_Score=60, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=172, Percent_Identity=44.1860465116279, Blast_Score=164, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.18 [H]

Molecular weight: Translated: 22450; Mature: 22450

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKMHHQKVYFCDDQALVSEQMQCLETLYDFNFTRPTEVKKREILLSKLFAEIGDNCYI
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
EPPLHANWGKHTHLGDNVYANFNLTLVDDTHIYIGHYVMIGPNVTIATAGHPIDPERRKK
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEEEEEECCCEEEEECCCCCCHHHHHH
AAQFNIPVYIGNNVWIGANCVILPGVTIGENSVIGAGSIVTKNIPANVIAVGNPCRILRE
HHEECCEEEECCEEEECCCEEEECCEEECCCCEEECCCEEECCCCCEEEEECCHHHHHHH
INDRDKEYYYKNLRFDGE
HCCCCHHEEEEEEEECCC
>Mature Secondary Structure
MKDKMHHQKVYFCDDQALVSEQMQCLETLYDFNFTRPTEVKKREILLSKLFAEIGDNCYI
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
EPPLHANWGKHTHLGDNVYANFNLTLVDDTHIYIGHYVMIGPNVTIATAGHPIDPERRKK
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEEEEEECCCEEEEECCCCCCHHHHHH
AAQFNIPVYIGNNVWIGANCVILPGVTIGENSVIGAGSIVTKNIPANVIAVGNPCRILRE
HHEECCEEEECCEEEECCCEEEECCEEECCCCEEECCCEEECCCCCEEEEECCHHHHHHH
INDRDKEYYYKNLRFDGE
HCCCCHHEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]