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The map label for this gene is pncB

Identifier: 119945433

GI number: 119945433

Start: 2105006

End: 2106226

Strand: Direct

Name: pncB

Synonym: Ping_1730

Alternate gene names: 119945433

Gene position: 2105006-2106226 (Clockwise)

Preceding gene: 119945432

Following gene: 119945434

Centisome position: 46.17

GC content: 46.44

Gene sequence:

>1221_bases
ATGAGTATAAAAAAGCTGGATTACTGGCTGATTGAGTCGTTGATGGATACAGATCTCTATAAAATTACTATGCTGCAGGC
CTATTATCATGCGCCGGAGTTCCGCCTTGTTGATATCGAGTGGAAGTTTGCCTGTCGTAACCGCAACGGCCTTGATTTAA
GCATCTTGATTCCGGAAATTTTTCGTCAGCTTGAGCATCTCTGCACACTCTCTTTCAGCGATGCCGAGCTCGACTATCTG
GCTGGTTTTTCTTTTATCAAACCAGATTTTATTGAATTTCTGCGTATCTTTCGACTCGATATGCGCTTTGTGCATATCGA
GGCGAAAGGTGAAGATATTAGCCTGCGCTTTAGCGGGCCATTGCTGCATGTCTCTCTGCTGGAGATTTATACACTGGCCA
TTATCAGTGAACTGCATACTTTTGTGAATTGTGGCGGTATTGATCTGAAGGTTGCACGGGAAAGACTGGCTGAAAAGATA
GCCTATCTGAAAGCTGAGGATGATCTGTCTGGTTTTAGTTTTGCCGATTTCGGCACTCGGCGGCGAGCGAGCAAAGCCTG
GCATGAAGAGGTGCTGCTGACCCTTAAAGAGCAATTACCGGCGTCTTTTTCCGGTACCAGCAGCCTGCATTTTGCACGCA
CCTTAGGTTTGCCTCCGATCGGTACTATGGCCCATGAATGGTTTCAAAGCTGGCAGGCAGTAACAAGACTGGCCGATGCC
CAGAAAGCGGCACTTGAGGGTTGGGTACAGGAATATCGGGGTCGATTGGGGATTGCGCTGACCGACTGTTATTCAATGGA
CTCTTTTATTCGGGATTTTTCCGATCCCTATTTTGGTAAACTTTACGATGGTCTTCGCCACGATAGTGGTTGTCCGTTTG
TGTGGGCTGAAAAGGCCATTTTGATGTATCAGCAGATGGGCATTGACCCGCTCAGTAAAACCCTGGTCTTTAGCGACGGG
TTAAATTTTCCGCGTATGCTGGAAATCTGGAAGCGGTTCAAGGGGCGCGCTAAAATCTCCTTTGGTATCGGCACAAATCT
GACCAATGATGTGGGTAATGTGCCACTAAATATTGTGATTAAAATGATCGCCGCTAATGGCCGACCGATAGCAAAAATAT
CCGATGAACCGGGAAAAAGTATGTGTGAAGATCTCGGTTATTTACAATATTTGGCCAGTCAGTATGGGATCGATCCGAGT
CTGGTGAAAATTTCTCAATAG

Upstream 100 bases:

>100_bases
CTTGCCGGGGAGTTGCCAGCGAGACCACTAAAAGTGCCTGTGCGGCAATGTCTGCTGCCGGGGCTGAACTGATTCAAGGC
AGTGGGGAAATGGAGTTGCA

Downstream 100 bases:

>100_bases
GACTGCGCTGATTTAGTTAGCAGTACAGTACCTGTCATTTTTGGCTGATTGACTATAAAACCTGCCAAAAATAGTTGACT
ATTATCCCCTTATTTCCTTT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSIKKLDYWLIESLMDTDLYKITMLQAYYHAPEFRLVDIEWKFACRNRNGLDLSILIPEIFRQLEHLCTLSFSDAELDYL
AGFSFIKPDFIEFLRIFRLDMRFVHIEAKGEDISLRFSGPLLHVSLLEIYTLAIISELHTFVNCGGIDLKVARERLAEKI
AYLKAEDDLSGFSFADFGTRRRASKAWHEEVLLTLKEQLPASFSGTSSLHFARTLGLPPIGTMAHEWFQSWQAVTRLADA
QKAALEGWVQEYRGRLGIALTDCYSMDSFIRDFSDPYFGKLYDGLRHDSGCPFVWAEKAILMYQQMGIDPLSKTLVFSDG
LNFPRMLEIWKRFKGRAKISFGIGTNLTNDVGNVPLNIVIKMIAANGRPIAKISDEPGKSMCEDLGYLQYLASQYGIDPS
LVKISQ

Sequences:

>Translated_406_residues
MSIKKLDYWLIESLMDTDLYKITMLQAYYHAPEFRLVDIEWKFACRNRNGLDLSILIPEIFRQLEHLCTLSFSDAELDYL
AGFSFIKPDFIEFLRIFRLDMRFVHIEAKGEDISLRFSGPLLHVSLLEIYTLAIISELHTFVNCGGIDLKVARERLAEKI
AYLKAEDDLSGFSFADFGTRRRASKAWHEEVLLTLKEQLPASFSGTSSLHFARTLGLPPIGTMAHEWFQSWQAVTRLADA
QKAALEGWVQEYRGRLGIALTDCYSMDSFIRDFSDPYFGKLYDGLRHDSGCPFVWAEKAILMYQQMGIDPLSKTLVFSDG
LNFPRMLEIWKRFKGRAKISFGIGTNLTNDVGNVPLNIVIKMIAANGRPIAKISDEPGKSMCEDLGYLQYLASQYGIDPS
LVKISQ
>Mature_405_residues
SIKKLDYWLIESLMDTDLYKITMLQAYYHAPEFRLVDIEWKFACRNRNGLDLSILIPEIFRQLEHLCTLSFSDAELDYLA
GFSFIKPDFIEFLRIFRLDMRFVHIEAKGEDISLRFSGPLLHVSLLEIYTLAIISELHTFVNCGGIDLKVARERLAEKIA
YLKAEDDLSGFSFADFGTRRRASKAWHEEVLLTLKEQLPASFSGTSSLHFARTLGLPPIGTMAHEWFQSWQAVTRLADAQ
KAALEGWVQEYRGRLGIALTDCYSMDSFIRDFSDPYFGKLYDGLRHDSGCPFVWAEKAILMYQQMGIDPLSKTLVFSDGL
NFPRMLEIWKRFKGRAKISFGIGTNLTNDVGNVPLNIVIKMIAANGRPIAKISDEPGKSMCEDLGYLQYLASQYGIDPSL
VKISQ

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family

Homologues:

Organism=Escherichia coli, GI1787162, Length=401, Percent_Identity=41.8952618453865, Blast_Score=301, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6324783, Length=422, Percent_Identity=31.042654028436, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNCB_PSYIN (A1SVJ9)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943113.1
- ProteinModelPortal:   A1SVJ9
- SMR:   A1SVJ9
- STRING:   A1SVJ9
- GeneID:   4627107
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1730
- eggNOG:   COG1488
- HOGENOM:   HBG325503
- OMA:   GNTFYGK
- PhylomeDB:   A1SVJ9
- ProtClustDB:   PRK05321
- BioCyc:   PING357804:PING_1730-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00570
- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638
- PANTHER:   PTHR11098:SF1
- PIRSF:   PIRSF000484
- TIGRFAMs:   TIGR01514

Pfam domain/function: PF04095 NAPRTase; SSF51690 Q_phspho_trans

EC number: =2.4.2.11

Molecular weight: Translated: 46300; Mature: 46169

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKKLDYWLIESLMDTDLYKITMLQAYYHAPEFRLVDIEWKFACRNRNGLDLSILIPEI
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEEHHHH
FRQLEHLCTLSFSDAELDYLAGFSFIKPDFIEFLRIFRLDMRFVHIEAKGEDISLRFSGP
HHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEEEEECCC
LLHVSLLEIYTLAIISELHTFVNCGGIDLKVARERLAEKIAYLKAEDDLSGFSFADFGTR
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHCCHH
RRASKAWHEEVLLTLKEQLPASFSGTSSLHFARTLGLPPIGTMAHEWFQSWQAVTRLADA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QKAALEGWVQEYRGRLGIALTDCYSMDSFIRDFSDPYFGKLYDGLRHDSGCPFVWAEKAI
HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHH
LMYQQMGIDPLSKTLVFSDGLNFPRMLEIWKRFKGRAKISFGIGTNLTNDVGNVPLNIVI
HHHHHHCCCHHHHHEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHH
KMIAANGRPIAKISDEPGKSMCEDLGYLQYLASQYGIDPSLVKISQ
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
SIKKLDYWLIESLMDTDLYKITMLQAYYHAPEFRLVDIEWKFACRNRNGLDLSILIPEI
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEEHHHH
FRQLEHLCTLSFSDAELDYLAGFSFIKPDFIEFLRIFRLDMRFVHIEAKGEDISLRFSGP
HHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEEEEECCC
LLHVSLLEIYTLAIISELHTFVNCGGIDLKVARERLAEKIAYLKAEDDLSGFSFADFGTR
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHCCHH
RRASKAWHEEVLLTLKEQLPASFSGTSSLHFARTLGLPPIGTMAHEWFQSWQAVTRLADA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QKAALEGWVQEYRGRLGIALTDCYSMDSFIRDFSDPYFGKLYDGLRHDSGCPFVWAEKAI
HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHH
LMYQQMGIDPLSKTLVFSDGLNFPRMLEIWKRFKGRAKISFGIGTNLTNDVGNVPLNIVI
HHHHHHCCCHHHHHEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHH
KMIAANGRPIAKISDEPGKSMCEDLGYLQYLASQYGIDPSLVKISQ
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA