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The map label for this gene is alkB [C]

Identifier: 119945408

GI number: 119945408

Start: 2076151

End: 2076783

Strand: Direct

Name: alkB [C]

Synonym: Ping_1701

Alternate gene names: 119945408

Gene position: 2076151-2076783 (Clockwise)

Preceding gene: 119945407

Following gene: 119945410

Centisome position: 45.53

GC content: 37.76

Gene sequence:

>633_bases
ATGTACAATATGGACTTATTTGCAGCACTAGAAGACTCACCTATTAATATCATTAATTGTGATGGTGTGGTGGAATATCA
TGGACTGTTAATTCCCTTTGACCAAGCTAATCATTATTTCGGTGTATTACTTGAAACAATCCAATGGAAGCATGATCAAG
CCAATATATTAGGTCAAATCATTGTTACTCAACGTAAAGTGGCTTGGCATGCTGACAAGCCTTTTCATTACACCTACTCT
AATATGACAAAAGTCGCTTTACCGTGGACGCTTGAATTATTACAACTGAAACAAAAGGTTGAAGACGCAACCGGGCATCA
ATTTAATGCTTGTTTACTTAATTTGTATCATAGTGGCCAAGAGGGCATGGCTTGGCACAGTGATGCAGAAAAAGATCTAC
AAAAAAACGCAGCAATCGCTTCATTAAGCTTTGGTGCTGAACGTAAATTCTCTTTTAAACATAAAGTGAATCAAAAAACT
ATTTCAGTCTCATTGCAACACGGCAGCCTGCTGGTAATGGGAGGTGACACTCAACGTCATTGGTTACATCGATTACCACC
CACTAAAAAAGTCACCACCCCCCGTATTAATTTAACCTTTAGAATGATTAACGAAACGAATCACCTATATTAA

Upstream 100 bases:

>100_bases
CTTTGTATTATTATTTATTGTTGAAATATTACAGGCCTTTATAATCAGCAATAAACCATTATTGATGATAGGTATCTAAT
AAGTTTAAATAGGAAATAAA

Downstream 100 bases:

>100_bases
AACCACCTTAAAAAATAAAGCTATTAAAATAGTTGGACCCATCTAATTAACCAAACATTAATCCGCTTCTATATTTTCGT
AATTATCCTTGATCATAAAA

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: Alkylated DNA Repair Protein; DNA-N1-Methyladenine Dioxygenase; DNA Repair System Specific For Alkylated DNA; 2OG-Fe(II) Oxygenase Superfamily Protein; 2OG-Fe(II) Oxygenase Family Oxidoreductase; Oxidoreductase 2OG-Fe(II) Oxygenase Family; Alkylated DNA Repair Protein-Like Protein; Oxidoreductase 2OG-Fe(II) Oxygenase Family Protein; CRISPR-Associated Family Protein; DNA Repair System Specific For Alkylated DNA Protein; 2OG-Fe(II) Oxygenase Family Protein; DNA Repair System Protein; Alkylated DNA Repair Protein AlkB

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MYNMDLFAALEDSPINIINCDGVVEYHGLLIPFDQANHYFGVLLETIQWKHDQANILGQIIVTQRKVAWHADKPFHYTYS
NMTKVALPWTLELLQLKQKVEDATGHQFNACLLNLYHSGQEGMAWHSDAEKDLQKNAAIASLSFGAERKFSFKHKVNQKT
ISVSLQHGSLLVMGGDTQRHWLHRLPPTKKVTTPRINLTFRMINETNHLY

Sequences:

>Translated_210_residues
MYNMDLFAALEDSPINIINCDGVVEYHGLLIPFDQANHYFGVLLETIQWKHDQANILGQIIVTQRKVAWHADKPFHYTYS
NMTKVALPWTLELLQLKQKVEDATGHQFNACLLNLYHSGQEGMAWHSDAEKDLQKNAAIASLSFGAERKFSFKHKVNQKT
ISVSLQHGSLLVMGGDTQRHWLHRLPPTKKVTTPRINLTFRMINETNHLY
>Mature_210_residues
MYNMDLFAALEDSPINIINCDGVVEYHGLLIPFDQANHYFGVLLETIQWKHDQANILGQIIVTQRKVAWHADKPFHYTYS
NMTKVALPWTLELLQLKQKVEDATGHQFNACLLNLYHSGQEGMAWHSDAEKDLQKNAAIASLSFGAERKFSFKHKVNQKT
ISVSLQHGSLLVMGGDTQRHWLHRLPPTKKVTTPRINLTFRMINETNHLY

Specific function: Probably Involved In The Repair Of Alkylated DNA. Provides Extensive Resistance To Alkylating Agents Such As Mms And Dms (Sn2 Agents), But Not To Mmng And Mnu (Sn1 Agents). [C]

COG id: COG3145

COG function: function code L; Alkylated DNA repair protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI21040275, Length=192, Percent_Identity=36.9791666666667, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI224451107, Length=190, Percent_Identity=35.2631578947368, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI48717226, Length=190, Percent_Identity=35.2631578947368, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI224451103, Length=190, Percent_Identity=35.2631578947368, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24109; Mature: 24109

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNMDLFAALEDSPINIINCDGVVEYHGLLIPFDQANHYFGVLLETIQWKHDQANILGQI
CCCCEEEEEECCCCCEEEECCCEEEECCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHE
IVTQRKVAWHADKPFHYTYSNMTKVALPWTLELLQLKQKVEDATGHQFNACLLNLYHSGQ
EEEEEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHEEEHHCCC
EGMAWHSDAEKDLQKNAAIASLSFGAERKFSFKHKVNQKTISVSLQHGSLLVMGGDTQRH
CCCEECCCHHHHHHHCCEEEEEECCCCCCEEHHHCCCCEEEEEEEECCEEEEECCCCHHH
WLHRLPPTKKVTTPRINLTFRMINETNHLY
HHHHCCCCCCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MYNMDLFAALEDSPINIINCDGVVEYHGLLIPFDQANHYFGVLLETIQWKHDQANILGQI
CCCCEEEEEECCCCCEEEECCCEEEECCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHE
IVTQRKVAWHADKPFHYTYSNMTKVALPWTLELLQLKQKVEDATGHQFNACLLNLYHSGQ
EEEEEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHEEEHHCCC
EGMAWHSDAEKDLQKNAAIASLSFGAERKFSFKHKVNQKTISVSLQHGSLLVMGGDTQRH
CCCEECCCHHHHHHHCCEEEEEECCCCCCEEHHHCCCCEEEEEEEECCEEEEECCCCHHH
WLHRLPPTKKVTTPRINLTFRMINETNHLY
HHHHCCCCCCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA