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The map label for this gene is ftsK [H]

Identifier: 119945374

GI number: 119945374

Start: 2018052

End: 2020619

Strand: Direct

Name: ftsK [H]

Synonym: Ping_1662

Alternate gene names: 119945374

Gene position: 2018052-2020619 (Clockwise)

Preceding gene: 119945373

Following gene: 119945375

Centisome position: 44.26

GC content: 41.59

Gene sequence:

>2568_bases
TTGTCGAAAAACAACTTTCTTAACCGGCTCTCCGGTGCACAAAAATTATTAGAAGTTGGCATCATTGTCTGTGCGTTTGT
CGCCATTTTTATTAGCATTTCATTGTTTACATTTTCCCCCGTTGATCCGAGTTGGTCACAGCAACAGTGGGTGGCAGAAA
TTCAAAATGCTGGTGGTATGGTGGGGGCTTGGATAGCTGATATTCTATTTTATGGTTTTGGATTACTCGCTTATTTTGTT
CCCGTACTGATCGCTTTTTTTGCATGGTTTTTTTTATGGAAACCAAAATTTAGTTTGGATATGGATTTTTTAAATCTGGG
ATTACGTATTATCGGGTTTATTTTTACTGTCTTTAGTACCACTGCATTAGCTTCTCTGAACTTTGATGATTATCACTATT
ATCCCTCCGGTGGATTGGTAGGTGACATTATCGCGCAAGGTATGTCAGGTTTTTTTAGTTTGTTAGCAATGAATTTTATC
CTGTTAACCCTGCTTGTTTCAGGCATAACCTTTTTACTCGGTTTTTCCTGGCTTAGTTTAATCGATAGTACGGGCGCTTT
TGTTATTATTTTTGTTACTTGGTTAATGACATTGCCAGAACGCTTTTCTCTTTGGAAAGAAAAGCGCAAGGCAGAAAAAA
TCTCACGGCTTAATGAAAAAGAGCCGGATTGGGGTGTTACAAAAAAACAGCGGAAGACGGTGGCTGAACAGCCAGCTTCT
TCTGATGTAGTGGCTAAAAAAAAGCCTGTTGAGAAGGTTTCTGGTGGCCCTGATGATTCAGATTTTAATTATTCAGACAT
TGATGATTCAGATATTGATCAACAATATTTTGATGCGCCCTTTGATATCGATGCTGTGGAAGACGATAAAAAGGATTTAC
ACAGCTTTTCATCTACATCACCGGAAATAGAAAACATTCCTGCTTTTATCACTGAATCCACACCACAAAAAGCAGTCAAC
CCGCAACCGGTCGTAGACAAAGCCAAACCTGCTATAGCCCCGAAAAATAATTTTGACCATCTTCCTGAACATGCCAAACC
CGCTATTAAACGGAAACCAGTGGAAGAAAATATGGCTGCCTTTCCGAGTATTGACCTGTTGGATCGGCCCGATAAAAAAA
TTCATCCCATCTCAAAGGAAGAGCTGGATACTGCGGCACGTTTAGTTGAAGCTAAATTACTTGAATTTAAAATTAAAGCT
AAAGTGGTTAATGTCTTACCCGGACCTGTTATTACACGTTTTGAACTTTCTTTAGCACCCGGGATGAAAGTGAGCACAGT
GAGCGGTTTAGAAAAAGACTTAGCACGTGCCTTGTCCGCAATGAGTGTGCGAGTGGTTGATCAAATTCCCGGGAAGTCGG
TCATTGCCTTAGAGTTACCTAATAAACATCGTGAAATTGTTTATTCTTCGGAAGTATTGGGCAGTGCAAAATTTAGAGAA
AGTAAATCTCCTTTAAGTATGGTGCTTGGAGCTGATATTTCCGGACAGCCTGTGGTGGTTGACCTTGCTAAAATGCCGCA
TCTTTTAGTGGCAGGTACAACGGGCTCGGGAAAATCTGTGGGCGTCAACTGTATGCTGGTCAGTTTGTTATATAAATCAA
CGCCTGAAGATGTACGTTTGATTTTAATTGACCCTAAAATGCTCGAATTAAGTGTTTATGAAGGGATCCCGCACTTATTA
GCGGAAGTCGTTACTGATATGAAGGATGCGGCAAATGCATTACGCTGGTGTGTTGGCGAAATGGAACGCCGTTATAAACT
TTTGTCTGAAATTGGTGTCCGTACATTAGCCAGTTTTAATAGTAAGGTAAAAGAAGCGGCCGATGAGGGCACGCCATTAA
CAGATCCTCTTTGGAAAGAGGGGGATAGTATGGATTTGACTGCCCCTGAATTAACAAAATTACCCAGCATTGTTGTGGTT
GTTGATGAATTTGCCGATATGATGATGATTGTGGGTAAAAAATGTGAGGAGTTAATTACCCGTATTGCACAAAAAGCACG
TGCCGCCGGCATTCACTTAATTTTAGCGACACAGCGTCCTTCGGTAGACGTTATCACCGGCTTAATTAAAGCAAACATTC
CTACTCGAATTGCATTCCAAGTCTCGAGTAAAATCGACTCAAGGACTATTTTAGGCATGCAGGGTGCTGAAACCCTGTTA
GGTCACGGTGATATGTTATATATGCCACCCGGGGTTGGCGTGCCGACACGTGTACATGGTGCCTTTGTTGATGACCATGA
AGTCCACCGTGTTGTTGCGGATTGGAAAAAACGCGGTGAGCCGAATTATGTACAGGAGATCATCGATGGTGACAGTGGCT
TAGATATGTTGTTACCTGGTGAGGAAGCTGAAGGTGCTAACGAGATTGATGCTTTATTTGATGAAGTAGTTGAATTTATT
ACCGAAACTCGTAAAGTATCAATATCAAGTATTCAGCGTAAATTTAGAATTGGTTACAATCGCTCGGCGCGTTTGGTGGA
TCAACTTCAAGCACAAGGTGTGATCAGTGCACCATCAGGTGCCAATAGTAATCGCGATGTTCTCGCTCCGCCTCCCGTTA
AGGATTAA

Upstream 100 bases:

>100_bases
AAAAATTTGGCTGCATTTACGTCACCAGCTTCCCGATGACTTTCTGGATTAAATAAACTAAATTAATGTTTCACTACTTT
TTTATAACAGGATAACTCTT

Downstream 100 bases:

>100_bases
TGTATGAAAAAAATAGTTATTGTCATTTCCATCTTGTTAACGTCATTTTTGTCTTCTGCTGTTTCGGCAGCGACAGATAG
TCAATTATTAAAAGAAAAAT

Product: DNA segregation ATPase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 855; Mature: 854

Protein sequence:

>855_residues
MSKNNFLNRLSGAQKLLEVGIIVCAFVAIFISISLFTFSPVDPSWSQQQWVAEIQNAGGMVGAWIADILFYGFGLLAYFV
PVLIAFFAWFFLWKPKFSLDMDFLNLGLRIIGFIFTVFSTTALASLNFDDYHYYPSGGLVGDIIAQGMSGFFSLLAMNFI
LLTLLVSGITFLLGFSWLSLIDSTGAFVIIFVTWLMTLPERFSLWKEKRKAEKISRLNEKEPDWGVTKKQRKTVAEQPAS
SDVVAKKKPVEKVSGGPDDSDFNYSDIDDSDIDQQYFDAPFDIDAVEDDKKDLHSFSSTSPEIENIPAFITESTPQKAVN
PQPVVDKAKPAIAPKNNFDHLPEHAKPAIKRKPVEENMAAFPSIDLLDRPDKKIHPISKEELDTAARLVEAKLLEFKIKA
KVVNVLPGPVITRFELSLAPGMKVSTVSGLEKDLARALSAMSVRVVDQIPGKSVIALELPNKHREIVYSSEVLGSAKFRE
SKSPLSMVLGADISGQPVVVDLAKMPHLLVAGTTGSGKSVGVNCMLVSLLYKSTPEDVRLILIDPKMLELSVYEGIPHLL
AEVVTDMKDAANALRWCVGEMERRYKLLSEIGVRTLASFNSKVKEAADEGTPLTDPLWKEGDSMDLTAPELTKLPSIVVV
VDEFADMMMIVGKKCEELITRIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILGMQGAETLL
GHGDMLYMPPGVGVPTRVHGAFVDDHEVHRVVADWKKRGEPNYVQEIIDGDSGLDMLLPGEEAEGANEIDALFDEVVEFI
TETRKVSISSIQRKFRIGYNRSARLVDQLQAQGVISAPSGANSNRDVLAPPPVKD

Sequences:

>Translated_855_residues
MSKNNFLNRLSGAQKLLEVGIIVCAFVAIFISISLFTFSPVDPSWSQQQWVAEIQNAGGMVGAWIADILFYGFGLLAYFV
PVLIAFFAWFFLWKPKFSLDMDFLNLGLRIIGFIFTVFSTTALASLNFDDYHYYPSGGLVGDIIAQGMSGFFSLLAMNFI
LLTLLVSGITFLLGFSWLSLIDSTGAFVIIFVTWLMTLPERFSLWKEKRKAEKISRLNEKEPDWGVTKKQRKTVAEQPAS
SDVVAKKKPVEKVSGGPDDSDFNYSDIDDSDIDQQYFDAPFDIDAVEDDKKDLHSFSSTSPEIENIPAFITESTPQKAVN
PQPVVDKAKPAIAPKNNFDHLPEHAKPAIKRKPVEENMAAFPSIDLLDRPDKKIHPISKEELDTAARLVEAKLLEFKIKA
KVVNVLPGPVITRFELSLAPGMKVSTVSGLEKDLARALSAMSVRVVDQIPGKSVIALELPNKHREIVYSSEVLGSAKFRE
SKSPLSMVLGADISGQPVVVDLAKMPHLLVAGTTGSGKSVGVNCMLVSLLYKSTPEDVRLILIDPKMLELSVYEGIPHLL
AEVVTDMKDAANALRWCVGEMERRYKLLSEIGVRTLASFNSKVKEAADEGTPLTDPLWKEGDSMDLTAPELTKLPSIVVV
VDEFADMMMIVGKKCEELITRIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILGMQGAETLL
GHGDMLYMPPGVGVPTRVHGAFVDDHEVHRVVADWKKRGEPNYVQEIIDGDSGLDMLLPGEEAEGANEIDALFDEVVEFI
TETRKVSISSIQRKFRIGYNRSARLVDQLQAQGVISAPSGANSNRDVLAPPPVKD
>Mature_854_residues
SKNNFLNRLSGAQKLLEVGIIVCAFVAIFISISLFTFSPVDPSWSQQQWVAEIQNAGGMVGAWIADILFYGFGLLAYFVP
VLIAFFAWFFLWKPKFSLDMDFLNLGLRIIGFIFTVFSTTALASLNFDDYHYYPSGGLVGDIIAQGMSGFFSLLAMNFIL
LTLLVSGITFLLGFSWLSLIDSTGAFVIIFVTWLMTLPERFSLWKEKRKAEKISRLNEKEPDWGVTKKQRKTVAEQPASS
DVVAKKKPVEKVSGGPDDSDFNYSDIDDSDIDQQYFDAPFDIDAVEDDKKDLHSFSSTSPEIENIPAFITESTPQKAVNP
QPVVDKAKPAIAPKNNFDHLPEHAKPAIKRKPVEENMAAFPSIDLLDRPDKKIHPISKEELDTAARLVEAKLLEFKIKAK
VVNVLPGPVITRFELSLAPGMKVSTVSGLEKDLARALSAMSVRVVDQIPGKSVIALELPNKHREIVYSSEVLGSAKFRES
KSPLSMVLGADISGQPVVVDLAKMPHLLVAGTTGSGKSVGVNCMLVSLLYKSTPEDVRLILIDPKMLELSVYEGIPHLLA
EVVTDMKDAANALRWCVGEMERRYKLLSEIGVRTLASFNSKVKEAADEGTPLTDPLWKEGDSMDLTAPELTKLPSIVVVV
DEFADMMMIVGKKCEELITRIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILGMQGAETLLG
HGDMLYMPPGVGVPTRVHGAFVDDHEVHRVVADWKKRGEPNYVQEIIDGDSGLDMLLPGEEAEGANEIDALFDEVVEFIT
ETRKVSISSIQRKFRIGYNRSARLVDQLQAQGVISAPSGANSNRDVLAPPPVKD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=507, Percent_Identity=65.0887573964497, Blast_Score=663, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 94082; Mature: 93951

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNNFLNRLSGAQKLLEVGIIVCAFVAIFISISLFTFSPVDPSWSQQQWVAEIQNAGGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCH
VGAWIADILFYGFGLLAYFVPVLIAFFAWFFLWKPKFSLDMDFLNLGLRIIGFIFTVFST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TALASLNFDDYHYYPSGGLVGDIIAQGMSGFFSLLAMNFILLTLLVSGITFLLGFSWLSL
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDSTGAFVIIFVTWLMTLPERFSLWKEKRKAEKISRLNEKEPDWGVTKKQRKTVAEQPAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
SDVVAKKKPVEKVSGGPDDSDFNYSDIDDSDIDQQYFDAPFDIDAVEDDKKDLHSFSSTS
CCCHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHCCCC
PEIENIPAFITESTPQKAVNPQPVVDKAKPAIAPKNNFDHLPEHAKPAIKRKPVEENMAA
CCHHCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCHHHHHH
FPSIDLLDRPDKKIHPISKEELDTAARLVEAKLLEFKIKAKVVNVLPGPVITRFELSLAP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
GMKVSTVSGLEKDLARALSAMSVRVVDQIPGKSVIALELPNKHREIVYSSEVLGSAKFRE
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHEEHHHHHCCHHHHC
SKSPLSMVLGADISGQPVVVDLAKMPHLLVAGTTGSGKSVGVNCMLVSLLYKSTPEDVRL
CCCCHHHHCCCCCCCCCEEEEHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEE
ILIDPKMLELSVYEGIPHLLAEVVTDMKDAANALRWCVGEMERRYKLLSEIGVRTLASFN
EEECCCCEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKVKEAADEGTPLTDPLWKEGDSMDLTAPELTKLPSIVVVVDEFADMMMIVGKKCEELIT
HHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
RIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILGMQGAETLL
HHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCHHHHH
GHGDMLYMPPGVGVPTRVHGAFVDDHEVHRVVADWKKRGEPNYVQEIIDGDSGLDMLLPG
CCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECC
EEAEGANEIDALFDEVVEFITETRKVSISSIQRKFRIGYNRSARLVDQLQAQGVISAPSG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCC
ANSNRDVLAPPPVKD
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKNNFLNRLSGAQKLLEVGIIVCAFVAIFISISLFTFSPVDPSWSQQQWVAEIQNAGGM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCH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CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]