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The map label for this gene is lolA

Identifier: 119945375

GI number: 119945375

Start: 2020623

End: 2021240

Strand: Direct

Name: lolA

Synonym: Ping_1663

Alternate gene names: 119945375

Gene position: 2020623-2021240 (Clockwise)

Preceding gene: 119945374

Following gene: 119945376

Centisome position: 44.32

GC content: 38.67

Gene sequence:

>618_bases
ATGAAAAAAATAGTTATTGTCATTTCCATCTTGTTAACGTCATTTTTGTCTTCTGCTGTTTCGGCAGCGACAGATAGTCA
ATTATTAAAAGAAAAATTAGCCAAATTTAGTTTTATTAATGCTGAATTTTCACAACAAGTGAGCAGTCCGGAAGGCAAAA
TATTAGATGATAGTCAGGGCATGTTAGCTATTTCGCGTCCGGGTAAATTTCGCTGGGAAGTGCTTATGCCAGAAGAGGAA
TTAATTGTCTCCGATGGTCAAACCATGTGGATGTACAGTCCCTTTATTGAACAGGTCACCCTGCTTAATTTAAGTGATGC
AATACAAGGCACCCCCTTTATACTGCTTTCCGGGGCTAATGAGTCGCAATGGGCTGACTATCAGGTAAATAAAGTTAATG
ATCAATTCATCGTCAAGAATATTGCCGGCACCGTTCAGGATAGATCTTTTATCTTTGAGTTTAATAAATCAAGTCAGGTT
AGCAAGTTTGTGGTTATTGAAGCGCTGGGACAACGCAGTGAGTTTAAATTGAGTCATAAAGTCTTATCTAAGCCCTGGGT
GGAAGGCTTTTTTGATTTTAGCATCCCAGCAGGTGTTGAAATAGATGATCAACGTTAA

Upstream 100 bases:

>100_bases
TTTGGTGGATCAACTTCAAGCACAAGGTGTGATCAGTGCACCATCAGGTGCCAATAGTAATCGCGATGTTCTCGCTCCGC
CTCCCGTTAAGGATTAATGT

Downstream 100 bases:

>100_bases
TGAAAGATCTTTTTGAATTTAATAATGATTTTCAGCCATTAGCGGCACGAATGCGGCCAAAATTTTTTTCAAATTACATT
GGCCAGGCACATATTATCGG

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKKIVIVISILLTSFLSSAVSAATDSQLLKEKLAKFSFINAEFSQQVSSPEGKILDDSQGMLAISRPGKFRWEVLMPEEE
LIVSDGQTMWMYSPFIEQVTLLNLSDAIQGTPFILLSGANESQWADYQVNKVNDQFIVKNIAGTVQDRSFIFEFNKSSQV
SKFVVIEALGQRSEFKLSHKVLSKPWVEGFFDFSIPAGVEIDDQR

Sequences:

>Translated_205_residues
MKKIVIVISILLTSFLSSAVSAATDSQLLKEKLAKFSFINAEFSQQVSSPEGKILDDSQGMLAISRPGKFRWEVLMPEEE
LIVSDGQTMWMYSPFIEQVTLLNLSDAIQGTPFILLSGANESQWADYQVNKVNDQFIVKNIAGTVQDRSFIFEFNKSSQV
SKFVVIEALGQRSEFKLSHKVLSKPWVEGFFDFSIPAGVEIDDQR
>Mature_205_residues
MKKIVIVISILLTSFLSSAVSAATDSQLLKEKLAKFSFINAEFSQQVSSPEGKILDDSQGMLAISRPGKFRWEVLMPEEE
LIVSDGQTMWMYSPFIEQVTLLNLSDAIQGTPFILLSGANESQWADYQVNKVNDQFIVKNIAGTVQDRSFIFEFNKSSQV
SKFVVIEALGQRSEFKLSHKVLSKPWVEGFFDFSIPAGVEIDDQR

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=208, Percent_Identity=36.0576923076923, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_PSYIN (A1SVE1)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943055.1
- ProteinModelPortal:   A1SVE1
- SMR:   A1SVE1
- STRING:   A1SVE1
- GeneID:   4626912
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1663
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   YSADFEQ
- PhylomeDB:   A1SVE1
- BioCyc:   PING357804:PING_1663-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23012; Mature: 23012

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVIVISILLTSFLSSAVSAATDSQLLKEKLAKFSFINAEFSQQVSSPEGKILDDSQG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCC
MLAISRPGKFRWEVLMPEEELIVSDGQTMWMYSPFIEQVTLLNLSDAIQGTPFILLSGAN
EEEEECCCCEEEEEECCCHHEEEECCCEEEEECHHHHHEEHCCHHHHHCCCCEEEEECCC
ESQWADYQVNKVNDQFIVKNIAGTVQDRSFIFEFNKSSQVSKFVVIEALGQRSEFKLSHK
CCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHEEEEEHHCCCCHHHHHHH
VLSKPWVEGFFDFSIPAGVEIDDQR
HHCCHHHHCEECCCCCCCCEECCCC
>Mature Secondary Structure
MKKIVIVISILLTSFLSSAVSAATDSQLLKEKLAKFSFINAEFSQQVSSPEGKILDDSQG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCC
MLAISRPGKFRWEVLMPEEELIVSDGQTMWMYSPFIEQVTLLNLSDAIQGTPFILLSGAN
EEEEECCCCEEEEEECCCHHEEEECCCEEEEECHHHHHEEHCCHHHHHCCCCEEEEECCC
ESQWADYQVNKVNDQFIVKNIAGTVQDRSFIFEFNKSSQVSKFVVIEALGQRSEFKLSHK
CCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHEEEEEHHCCCCHHHHHHH
VLSKPWVEGFFDFSIPAGVEIDDQR
HHCCHHHHCEECCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA