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The map label for this gene is rlmM

Identifier: 119945329

GI number: 119945329

Start: 1966609

End: 1967706

Strand: Direct

Name: rlmM

Synonym: Ping_1613

Alternate gene names: 119945329

Gene position: 1966609-1967706 (Clockwise)

Preceding gene: 119945328

Following gene: 119945334

Centisome position: 43.13

GC content: 40.62

Gene sequence:

>1098_bases
ATGTTAGGAATTTTATTATATTGTCGCCCGGGGTTTGAAAACGACTGCGCTAATGAGCTGCAGGACAAAGCAACGGCATT
AGAAGTCTTTGGTTTTGTGAAAACAAAACGTAATAGCGGTTATGTTTTCTACCAGTGTTATGACCCACAACAGGTGGAAT
ATTTATTAGAAAAGCTTGATTATAAACAGCTGATATTTGCACGGCAGTTGATTGCAGTTAAAGCCTTTATTAATGATTTA
CCACTGGACGACCGCATTAGTCCTATTTTAGAAATTACGCGTAATCTGCCATTAGGTGGCGATCTTTATGTTGAAACACC
TGAGGGTGACGATACTAAACCACTATTAACTTTTTGCCGCAAATTTACAGTGCCTTTGCGTCAGGCATTAAGAAAACATA
ATAGCCTCACCGCAAAAGAAAACCGCAATAAAATTTTTTATCATTTATGTTTTTTGGATAATAAATCTGCTTATATCGGT
TTTTCTGTGCCGCATAACCGGAGTGAATTTTATATGGGGATCCCCCGTTTACGTTCACCAAGTGAAGCACCCAGTCGTTC
TACATTAAAGCTTGATGAAGCTATTCAGGTTTTTCTTACGGCGGAAGAACAGCAAGAGCGCTTACATTCAGGAATGCGTG
CGGTCGATTTAGGTGCCTGTCCCGGTGGCTGGACATACCAGCTTGTTCGCCGTGGTTTATTTGTGACTGCTATTGATAAT
GGTGCTATGGCACAAAGCCTGATGGATACCGGTCAAGTTACTCATTATACGGTTGACGGGTTTAAATATGAACCTGAGCG
TAAGAACATAGACTGGCTGGTCTGTGACATGATAGAGAAACCCAAGCGTGTGGCTAAATTGATGGGGCAATGGTTAATTG
ACGGCTGGTGTAAAGAAGCTATTTTCAACTTTAAATTGCCCATGAAAAAACGTTATCAGGAAGCCTCTGAAGATATTAAA
ATATTAACCGATATGTTCGAAAAGGAAGATCTTCAGTATGAACTGCAAGCGAAGCAGCTTTATCATGATCGTGAAGAGAT
AACCCTGCATGTGCGTTTAATCGGTAATCACTGGGGTAAACAACTGGGTAACGGATAA

Upstream 100 bases:

>100_bases
CTTTCATTATGCCGAGTTTAGGTTAAGTAAATTGTGAATGAACGTTTTAACAGAATGAAAATTTCCACGTCGATGACGGG
AACTCATTCTAGAGGTAAGT

Downstream 100 bases:

>100_bases
TACCAAATCTATTCATTTTCTGTTCATTTATGCGGGTTAAAATACATGCTGGCTAGACATAAAACGTCGTTTTAGTCTCT
GTGCTTGATTTGATTCATAA

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MLGILLYCRPGFENDCANELQDKATALEVFGFVKTKRNSGYVFYQCYDPQQVEYLLEKLDYKQLIFARQLIAVKAFINDL
PLDDRISPILEITRNLPLGGDLYVETPEGDDTKPLLTFCRKFTVPLRQALRKHNSLTAKENRNKIFYHLCFLDNKSAYIG
FSVPHNRSEFYMGIPRLRSPSEAPSRSTLKLDEAIQVFLTAEEQQERLHSGMRAVDLGACPGGWTYQLVRRGLFVTAIDN
GAMAQSLMDTGQVTHYTVDGFKYEPERKNIDWLVCDMIEKPKRVAKLMGQWLIDGWCKEAIFNFKLPMKKRYQEASEDIK
ILTDMFEKEDLQYELQAKQLYHDREEITLHVRLIGNHWGKQLGNG

Sequences:

>Translated_365_residues
MLGILLYCRPGFENDCANELQDKATALEVFGFVKTKRNSGYVFYQCYDPQQVEYLLEKLDYKQLIFARQLIAVKAFINDL
PLDDRISPILEITRNLPLGGDLYVETPEGDDTKPLLTFCRKFTVPLRQALRKHNSLTAKENRNKIFYHLCFLDNKSAYIG
FSVPHNRSEFYMGIPRLRSPSEAPSRSTLKLDEAIQVFLTAEEQQERLHSGMRAVDLGACPGGWTYQLVRRGLFVTAIDN
GAMAQSLMDTGQVTHYTVDGFKYEPERKNIDWLVCDMIEKPKRVAKLMGQWLIDGWCKEAIFNFKLPMKKRYQEASEDIK
ILTDMFEKEDLQYELQAKQLYHDREEITLHVRLIGNHWGKQLGNG
>Mature_365_residues
MLGILLYCRPGFENDCANELQDKATALEVFGFVKTKRNSGYVFYQCYDPQQVEYLLEKLDYKQLIFARQLIAVKAFINDL
PLDDRISPILEITRNLPLGGDLYVETPEGDDTKPLLTFCRKFTVPLRQALRKHNSLTAKENRNKIFYHLCFLDNKSAYIG
FSVPHNRSEFYMGIPRLRSPSEAPSRSTLKLDEAIQVFLTAEEQQERLHSGMRAVDLGACPGGWTYQLVRRGLFVTAIDN
GAMAQSLMDTGQVTHYTVDGFKYEPERKNIDWLVCDMIEKPKRVAKLMGQWLIDGWCKEAIFNFKLPMKKRYQEASEDIK
ILTDMFEKEDLQYELQAKQLYHDREEITLHVRLIGNHWGKQLGNG

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=355, Percent_Identity=53.5211267605634, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_PSYIN (A1SV95)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943009.1
- ProteinModelPortal:   A1SV95
- SMR:   A1SV95
- STRING:   A1SV95
- GeneID:   4624642
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1613
- eggNOG:   COG2933
- HOGENOM:   HBG681972
- OMA:   LYCRPGF
- PhylomeDB:   A1SV95
- ProtClustDB:   PRK11760
- BioCyc:   PING357804:PING_1613-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 42255; Mature: 42255

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGILLYCRPGFENDCANELQDKATALEVFGFVKTKRNSGYVFYQCYDPQQVEYLLEKLD
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCHHHHHHHHHHCC
YKQLIFARQLIAVKAFINDLPLDDRISPILEITRNLPLGGDLYVETPEGDDTKPLLTFCR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHH
KFTVPLRQALRKHNSLTAKENRNKIFYHLCFLDNKSAYIGFSVPHNRSEFYMGIPRLRSP
HHCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCCEEECCCCCCCC
SEAPSRSTLKLDEAIQVFLTAEEQQERLHSGMRAVDLGACPGGWTYQLVRRGLFVTAIDN
CCCCCCCCEEHHHHHEEEEECHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCEEEEEECC
GAMAQSLMDTGQVTHYTVDGFKYEPERKNIDWLVCDMIEKPKRVAKLMGQWLIDGWCKEA
CHHHHHHHHCCCEEEEEECCEEECCCCCCCCEEEHHHHHCHHHHHHHHHHHHHHHHHHHH
IFNFKLPMKKRYQEASEDIKILTDMFEKEDLQYELQAKQLYHDREEITLHVRLIGNHWGK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCHHHH
QLGNG
HCCCC
>Mature Secondary Structure
MLGILLYCRPGFENDCANELQDKATALEVFGFVKTKRNSGYVFYQCYDPQQVEYLLEKLD
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCHHHHHHHHHHCC
YKQLIFARQLIAVKAFINDLPLDDRISPILEITRNLPLGGDLYVETPEGDDTKPLLTFCR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHH
KFTVPLRQALRKHNSLTAKENRNKIFYHLCFLDNKSAYIGFSVPHNRSEFYMGIPRLRSP
HHCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCCEEECCCCCCCC
SEAPSRSTLKLDEAIQVFLTAEEQQERLHSGMRAVDLGACPGGWTYQLVRRGLFVTAIDN
CCCCCCCCEEHHHHHEEEEECHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCEEEEEECC
GAMAQSLMDTGQVTHYTVDGFKYEPERKNIDWLVCDMIEKPKRVAKLMGQWLIDGWCKEA
CHHHHHHHHCCCEEEEEECCEEECCCCCCCCEEEHHHHHCHHHHHHHHHHHHHHHHHHHH
IFNFKLPMKKRYQEASEDIKILTDMFEKEDLQYELQAKQLYHDREEITLHVRLIGNHWGK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCHHHH
QLGNG
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA