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The map label for this gene is cry2 [H]

Identifier: 119945274

GI number: 119945274

Start: 1897530

End: 1899083

Strand: Direct

Name: cry2 [H]

Synonym: Ping_1549

Alternate gene names: 119945274

Gene position: 1897530-1899083 (Clockwise)

Preceding gene: 119945273

Following gene: 119945275

Centisome position: 41.62

GC content: 39.64

Gene sequence:

>1554_bases
ATGGCAGCTAATATCGCGGCAACTAATATCCGGGCAGATAGTGTTGTCAATATTGTTTGGTTAAAGCGTGACCTGCGGCT
TAGCGATCATCAGCCGCTGAGCGAATCAATTCAGTCGGGTTTAACTCTATTGTATTACGTTTTTGAGCCTTTATTAATAG
CAGATCCTCATTACGACAAACGACATTGGCGTTTTATTTGGCAATCAATTGAAGATATTAACACTCAGCTCAGCGCTTTT
AATGCCCAGATTTATGTTTATTTTGGTGATGCGGTTGCCGGCCTTAATGAAATTCAGCAGCGCTTTAACATTACCGGTTT
ATTTAGCCATGAAGAAGTCGGCTTATTGTCTACTTTTGAGCGCGATAAAGCGGTTAACAAATGGTGTAAAGCACAAAACA
TTGTTTGGCATGAAAGTGCATCAGGAGCGGTAACTCGCGGTAAAAAAAATAGAAATAATTGGGACAAAGATTGGCGTAAG
ATAATGAAAGCTGAGTTATGTCAGCCAGCGTTGTCTTGTAACACACTGCTAAGTAAGCAATGTTTAGAGCGGTTACCTCA
GTTTATTTTACCTGTGTCGTGGTCAACACCTGACGATTTTATGTTAAAAGGTGGTGAGCTTTGGGCGCAAAAAATGCTGC
AGTCATTTTTGAATGGCCGAGGTAAAAACTATCATTTTGACATATCCAAACCGCAGGCAAGTCGTAAAAGTTGTTCACGG
TTATCGCCTTATTTAGCTTGGGGCAATATAAGCTTAAGGCAGTTCTATCAAATCATTTTAATGAAAAGACCACAAAACGG
TTGGAAACGACCGATAGATGCACTGGCATCTCGGCTGCATTGGCATTGCCATTTTATACAAAAATTTGAAAGCGAACATC
AAATGCAGTGGCGTCCGGTAAATCGAGCTTACAGTAATTTTAGCTATCCTGACCTTCACTGTGGTTTGAGTGTTGAAACG
CGATTAAATAAATGGAAAACGGCGCAAACAGGCTATCCGCTAGTTGATGCTTGCATGCTTTGTTTAATAAAAACAGGGTA
TATAAATTTTCGCATGCGCGCGATGTTAGTCAGTTTTTTGTGCCATCATTTACTGCTAGATTGGCGTTTAGGCGTTAGTT
ATTTAGCGAAATTATTTCTCGATTTTGAGCCAGGAATTCACTATCCACAATTTCAAATGCAGTCAGGGGTAACTGGCACT
AATATCATTCGGGTTTATAATCCAGTGAAACAGTCATTGGAAAAAGATAAAGATGGTCTATTTATTAGAACATGGTTGCC
ACAATTATCAGAGTTGCCAAATGAAATTATTCATACCCCTTGGCAATTATCGCCAATGGAGCAACAGCTTTATCAATGTC
AATTAGGTGAGACTTATCCTTTACCTATCGTGGATATCAACGAAACAGGTAAGATTGCCCGCGATTTACTCTGGGGTTTT
AGAAAGCGATTTGACAGTAAAAAAGAAGGTCAGCGCATTGTAGCAAAACATGTTCGAGCGACTAAAAAACCGACGAAAGC
AAGAAAGCCTAAACCATTAGAAAAGTTAATATGA

Upstream 100 bases:

>100_bases
CCAAGCACAATGGATAGATCTAAGTCAGCAAAGCACTCAAGCCAATCAAGCACTAGACTCTGTCGATGCTGCAGATTGGC
CGGTGCTGCAGTAAGCTAGA

Downstream 100 bases:

>100_bases
TAAGCGATGCATAAAAAATTATTGTTACCCCATAAAAATTGTCTCACCTGTAAAAAAGATTTTCTATGGCGCAAAAAATG
GCAAGCCAATTGGGAGCATG

Product: deoxyribodipyrimidine photo-lyase

Products: 2 pyrimidine residues (in DNA) [C]

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MAANIAATNIRADSVVNIVWLKRDLRLSDHQPLSESIQSGLTLLYYVFEPLLIADPHYDKRHWRFIWQSIEDINTQLSAF
NAQIYVYFGDAVAGLNEIQQRFNITGLFSHEEVGLLSTFERDKAVNKWCKAQNIVWHESASGAVTRGKKNRNNWDKDWRK
IMKAELCQPALSCNTLLSKQCLERLPQFILPVSWSTPDDFMLKGGELWAQKMLQSFLNGRGKNYHFDISKPQASRKSCSR
LSPYLAWGNISLRQFYQIILMKRPQNGWKRPIDALASRLHWHCHFIQKFESEHQMQWRPVNRAYSNFSYPDLHCGLSVET
RLNKWKTAQTGYPLVDACMLCLIKTGYINFRMRAMLVSFLCHHLLLDWRLGVSYLAKLFLDFEPGIHYPQFQMQSGVTGT
NIIRVYNPVKQSLEKDKDGLFIRTWLPQLSELPNEIIHTPWQLSPMEQQLYQCQLGETYPLPIVDINETGKIARDLLWGF
RKRFDSKKEGQRIVAKHVRATKKPTKARKPKPLEKLI

Sequences:

>Translated_517_residues
MAANIAATNIRADSVVNIVWLKRDLRLSDHQPLSESIQSGLTLLYYVFEPLLIADPHYDKRHWRFIWQSIEDINTQLSAF
NAQIYVYFGDAVAGLNEIQQRFNITGLFSHEEVGLLSTFERDKAVNKWCKAQNIVWHESASGAVTRGKKNRNNWDKDWRK
IMKAELCQPALSCNTLLSKQCLERLPQFILPVSWSTPDDFMLKGGELWAQKMLQSFLNGRGKNYHFDISKPQASRKSCSR
LSPYLAWGNISLRQFYQIILMKRPQNGWKRPIDALASRLHWHCHFIQKFESEHQMQWRPVNRAYSNFSYPDLHCGLSVET
RLNKWKTAQTGYPLVDACMLCLIKTGYINFRMRAMLVSFLCHHLLLDWRLGVSYLAKLFLDFEPGIHYPQFQMQSGVTGT
NIIRVYNPVKQSLEKDKDGLFIRTWLPQLSELPNEIIHTPWQLSPMEQQLYQCQLGETYPLPIVDINETGKIARDLLWGF
RKRFDSKKEGQRIVAKHVRATKKPTKARKPKPLEKLI
>Mature_516_residues
AANIAATNIRADSVVNIVWLKRDLRLSDHQPLSESIQSGLTLLYYVFEPLLIADPHYDKRHWRFIWQSIEDINTQLSAFN
AQIYVYFGDAVAGLNEIQQRFNITGLFSHEEVGLLSTFERDKAVNKWCKAQNIVWHESASGAVTRGKKNRNNWDKDWRKI
MKAELCQPALSCNTLLSKQCLERLPQFILPVSWSTPDDFMLKGGELWAQKMLQSFLNGRGKNYHFDISKPQASRKSCSRL
SPYLAWGNISLRQFYQIILMKRPQNGWKRPIDALASRLHWHCHFIQKFESEHQMQWRPVNRAYSNFSYPDLHCGLSVETR
LNKWKTAQTGYPLVDACMLCLIKTGYINFRMRAMLVSFLCHHLLLDWRLGVSYLAKLFLDFEPGIHYPQFQMQSGVTGTN
IIRVYNPVKQSLEKDKDGLFIRTWLPQLSELPNEIIHTPWQLSPMEQQLYQCQLGETYPLPIVDINETGKIARDLLWGFR
KRFDSKKEGQRIVAKHVRATKKPTKARKPKPLEKLI

Specific function: Has no photolyase activity [H]

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI188536100, Length=495, Percent_Identity=24.4444444444444, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI4758072, Length=502, Percent_Identity=25.0996015936255, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI188536103, Length=447, Percent_Identity=24.3847874720358, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1786926, Length=479, Percent_Identity=25.8872651356994, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324962, Length=341, Percent_Identity=26.6862170087977, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17137248, Length=501, Percent_Identity=24.750499001996, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24585455, Length=501, Percent_Identity=24.750499001996, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648152, Length=514, Percent_Identity=22.3735408560311, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: 4.1.99.3 [C]

Molecular weight: Translated: 60269; Mature: 60138

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANIAATNIRADSVVNIVWLKRDLRLSDHQPLSESIQSGLTLLYYVFEPLLIADPHYDK
CCCCCEECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCH
RHWRFIWQSIEDINTQLSAFNAQIYVYFGDAVAGLNEIQQRFNITGLFSHEEVGLLSTFE
HHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
RDKAVNKWCKAQNIVWHESASGAVTRGKKNRNNWDKDWRKIMKAELCQPALSCNTLLSKQ
HHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
CLERLPQFILPVSWSTPDDFMLKGGELWAQKMLQSFLNGRGKNYHFDISKPQASRKSCSR
HHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LSPYLAWGNISLRQFYQIILMKRPQNGWKRPIDALASRLHWHCHFIQKFESEHQMQWRPV
CCCEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCH
NRAYSNFSYPDLHCGLSVETRLNKWKTAQTGYPLVDACMLCLIKTGYINFRMRAMLVSFL
HHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
CHHLLLDWRLGVSYLAKLFLDFEPGIHYPQFQMQSGVTGTNIIRVYNPVKQSLEKDKDGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHCCCCCE
FIRTWLPQLSELPNEIIHTPWQLSPMEQQLYQCQLGETYPLPIVDINETGKIARDLLWGF
EEEHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHH
RKRFDSKKEGQRIVAKHVRATKKPTKARKPKPLEKLI
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC
>Mature Secondary Structure 
AANIAATNIRADSVVNIVWLKRDLRLSDHQPLSESIQSGLTLLYYVFEPLLIADPHYDK
CCCCEECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCH
RHWRFIWQSIEDINTQLSAFNAQIYVYFGDAVAGLNEIQQRFNITGLFSHEEVGLLSTFE
HHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
RDKAVNKWCKAQNIVWHESASGAVTRGKKNRNNWDKDWRKIMKAELCQPALSCNTLLSKQ
HHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
CLERLPQFILPVSWSTPDDFMLKGGELWAQKMLQSFLNGRGKNYHFDISKPQASRKSCSR
HHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LSPYLAWGNISLRQFYQIILMKRPQNGWKRPIDALASRLHWHCHFIQKFESEHQMQWRPV
CCCEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCH
NRAYSNFSYPDLHCGLSVETRLNKWKTAQTGYPLVDACMLCLIKTGYINFRMRAMLVSFL
HHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
CHHLLLDWRLGVSYLAKLFLDFEPGIHYPQFQMQSGVTGTNIIRVYNPVKQSLEKDKDGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHCCCCCE
FIRTWLPQLSELPNEIIHTPWQLSPMEQQLYQCQLGETYPLPIVDINETGKIARDLLWGF
EEEHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHH
RKRFDSKKEGQRIVAKHVRATKKPTKARKPKPLEKLI
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: ATP; FADH2; Flavin; pterin [C]

Metal ions: NA

Kcat value (1/min): 2.4 [C]

Specific activity: NA

Km value (mM): NA

Substrates: cyclobutadipyrimidine (in DNA) [C]

Specific reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA) [C]

General reaction: C-C-bond cleavage [C]

Inhibitor: yeast DNA [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]