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The map label for this gene is ribB [H]

Identifier: 119945178

GI number: 119945178

Start: 1775666

End: 1776772

Strand: Direct

Name: ribB [H]

Synonym: Ping_1442

Alternate gene names: 119945178

Gene position: 1775666-1776772 (Clockwise)

Preceding gene: 119945177

Following gene: 119945179

Centisome position: 38.94

GC content: 44.17

Gene sequence:

>1107_bases
ATGAAATTAAGTACTACCGCCGAAATTATCGAAGATATTCGTTTAGGTAAAATGGTTATTTTGATGGATGATGAAGATCG
CGAAAACGAGGGCGATCTAATTATGGCTGCCGATTTAGTCACCCCGGAAGCGATTAACTTTATGGCAACCTATGGTCGTG
GTCTGGTTTGTCTAACATTAACGGCTGAGCGCTGTGAGCAGCTTAAGTTACCGCTAATGGTTGATGATAATACCGCTGCA
TTTTCGACCAATTTTACGGTTTCTATTGAAGCAGCCCTTGGTGTCACCACGGGTATTTCGGCTGCCGACCGTGCCATTAC
CGTACAAGCTGCAGTGGCTAAAGACGCAAAACCTACGGACATTGTTATGCCTGGTCATATCTTTCCACTGATGGCACAAG
CGGGTGGCGTATTAACCCGTGCCGGGCACACTGAAGCGGGCTGCGACTTAGCACGTTTGGCCGGTCGGGAACCCGCTGGC
GTGATTGTTGAAATATTAAATAAAGATGGCACGATGGCGCGCCGTCCAGATCTTGAAATTTTTGCAGAAGAAAAAGGGAT
AAAATTAGGCACTGTTGCAGATTTAATTGAATACCGTAATAACAATGAAACCACTATTGAACGTGTCAGCGCTTGCAAAT
TACCGACGGAATATGGTGATTTTGATTTAATCGCTTATCAGGACACTATCGATAAACAGGTTCATTTTGCATTAGTCAAT
GGCGAAATTAAAACCGGGCAAACCACCAATGTGCGAGTGCATTTACAAAACACCTTCGCCGATAACTTCTTTTCCGATCG
TTTAAGTAAACGCACTTGGCCATTAAATGATGCGCTGCAGCGTTTAAATAAAGACGGTGGCGTATTGGTTATGTTAGCCC
ATCAGGAAACACCGAGTTCATTGATTGAACAAGTAAAACAAATTGCCAATGAAGATGCCGGTGAACGTGTCGCTAAAAAA
GAGCAAAAAGTGAGCCGCCGTGTGGGGGTTGGTTCGCAGATCCTGCGTGATTTAGGCGTGCAAAAAATGGCCCTGTTAAG
CTCTGAGAAAAAATATCATGCGTTATCAGGATTTGGTTTAGAAGTGGTCGATTACATTACTGAATAG

Upstream 100 bases:

>100_bases
AGCTTCGACAAGTCACCATGACAATAAACCACCTAACCATGGGATCTGCTTGCTAAAAGTGGTTTCTTAGGTCAAGCCGT
AAAATAGATAGGAAAATAAA

Downstream 100 bases:

>100_bases
CCTGTGTTGCTCTTCGTAATAAAGTTAACAATTAATAAAAATGTGTTAAGATTCACAAAATTTTGCAATAAGGGTAGTAA
ATGAAAATTATTGAAGGTGG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKLSTTAEIIEDIRLGKMVILMDDEDRENEGDLIMAADLVTPEAINFMATYGRGLVCLTLTAERCEQLKLPLMVDDNTAA
FSTNFTVSIEAALGVTTGISAADRAITVQAAVAKDAKPTDIVMPGHIFPLMAQAGGVLTRAGHTEAGCDLARLAGREPAG
VIVEILNKDGTMARRPDLEIFAEEKGIKLGTVADLIEYRNNNETTIERVSACKLPTEYGDFDLIAYQDTIDKQVHFALVN
GEIKTGQTTNVRVHLQNTFADNFFSDRLSKRTWPLNDALQRLNKDGGVLVMLAHQETPSSLIEQVKQIANEDAGERVAKK
EQKVSRRVGVGSQILRDLGVQKMALLSSEKKYHALSGFGLEVVDYITE

Sequences:

>Translated_368_residues
MKLSTTAEIIEDIRLGKMVILMDDEDRENEGDLIMAADLVTPEAINFMATYGRGLVCLTLTAERCEQLKLPLMVDDNTAA
FSTNFTVSIEAALGVTTGISAADRAITVQAAVAKDAKPTDIVMPGHIFPLMAQAGGVLTRAGHTEAGCDLARLAGREPAG
VIVEILNKDGTMARRPDLEIFAEEKGIKLGTVADLIEYRNNNETTIERVSACKLPTEYGDFDLIAYQDTIDKQVHFALVN
GEIKTGQTTNVRVHLQNTFADNFFSDRLSKRTWPLNDALQRLNKDGGVLVMLAHQETPSSLIEQVKQIANEDAGERVAKK
EQKVSRRVGVGSQILRDLGVQKMALLSSEKKYHALSGFGLEVVDYITE
>Mature_368_residues
MKLSTTAEIIEDIRLGKMVILMDDEDRENEGDLIMAADLVTPEAINFMATYGRGLVCLTLTAERCEQLKLPLMVDDNTAA
FSTNFTVSIEAALGVTTGISAADRAITVQAAVAKDAKPTDIVMPGHIFPLMAQAGGVLTRAGHTEAGCDLARLAGREPAG
VIVEILNKDGTMARRPDLEIFAEEKGIKLGTVADLIEYRNNNETTIERVSACKLPTEYGDFDLIAYQDTIDKQVHFALVN
GEIKTGQTTNVRVHLQNTFADNFFSDRLSKRTWPLNDALQRLNKDGGVLVMLAHQETPSSLIEQVKQIANEDAGERVAKK
EQKVSRRVGVGSQILRDLGVQKMALLSSEKKYHALSGFGLEVVDYITE

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=191, Percent_Identity=56.020942408377, Blast_Score=219, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=42.2885572139304, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40222; Mature: 40222

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTTAEIIEDIRLGKMVILMDDEDRENEGDLIMAADLVTPEAINFMATYGRGLVCLTL
CCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEE
TAERCEQLKLPLMVDDNTAAFSTNFTVSIEAALGVTTGISAADRAITVQAAVAKDAKPTD
EHHHHHHCCCCEEECCCCEEEEECEEEEEEEEECEECCCCCCCCEEEEEEECCCCCCCCE
IVMPGHIFPLMAQAGGVLTRAGHTEAGCDLARLAGREPAGVIVEILNKDGTMARRPDLEI
EEECCHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEE
FAEEKGIKLGTVADLIEYRNNNETTIERVSACKLPTEYGDFDLIAYQDTIDKQVHFALVN
EECCCCCEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEEE
GEIKTGQTTNVRVHLQNTFADNFFSDRLSKRTWPLNDALQRLNKDGGVLVMLAHQETPSS
CEEECCCCEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCHHH
LIEQVKQIANEDAGERVAKKEQKVSRRVGVGSQILRDLGVQKMALLSSEKKYHALSGFGL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHCCCCHHHHCCCCH
EVVDYITE
HHHHHHCC
>Mature Secondary Structure
MKLSTTAEIIEDIRLGKMVILMDDEDRENEGDLIMAADLVTPEAINFMATYGRGLVCLTL
CCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEE
TAERCEQLKLPLMVDDNTAAFSTNFTVSIEAALGVTTGISAADRAITVQAAVAKDAKPTD
EHHHHHHCCCCEEECCCCEEEEECEEEEEEEEECEECCCCCCCCEEEEEEECCCCCCCCE
IVMPGHIFPLMAQAGGVLTRAGHTEAGCDLARLAGREPAGVIVEILNKDGTMARRPDLEI
EEECCHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEE
FAEEKGIKLGTVADLIEYRNNNETTIERVSACKLPTEYGDFDLIAYQDTIDKQVHFALVN
EECCCCCEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEEE
GEIKTGQTTNVRVHLQNTFADNFFSDRLSKRTWPLNDALQRLNKDGGVLVMLAHQETPSS
CEEECCCCEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCHHH
LIEQVKQIANEDAGERVAKKEQKVSRRVGVGSQILRDLGVQKMALLSSEKKYHALSGFGL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHCCCCHHHHCCCCH
EVVDYITE
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]