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The map label for this gene is ribH

Identifier: 119945179

GI number: 119945179

Start: 1776853

End: 1777320

Strand: Direct

Name: ribH

Synonym: Ping_1443

Alternate gene names: 119945179

Gene position: 1776853-1777320 (Clockwise)

Preceding gene: 119945178

Following gene: 119945180

Centisome position: 38.97

GC content: 43.16

Gene sequence:

>468_bases
ATGAAAATTATTGAAGGTGGCTTAGCGGCACCACAAGCGCAGATCGCAATCGTTATCTCTCGTTTTAATAGCTTTATTAA
CGAGCAGTTATTAGCAGGAGCAATCGATACCCTTAAGCGTACTGGTCAAGTTGCTGATGATAATATTACTGTTGTACGTG
TCCCTGGTGCCGTTGAGCTTCCATTGGTCGCTAAACGTGTTGCCGCCTCTAAAAAGTTCGATGCCATTATCGCATTAGGG
ACTGTTATTCGTGGTGGTACACCCCACTTTGAATTTGTTGCTGGCGAATGTAATAAGGGCCTTGGTCAAGTCTCTATGGA
CTTTGATATACCGGTTTCCTTCGGGGTATTAACAACTGATTCAATAGAACAAGCGATTGAACGTGCGGGAACTAAAATGG
GTAATAAAGGCAGTGAAGCGGCCTTAAGCGCATTAGAAATGGTCAATGTTATGGCGGAGTTTAAATAA

Upstream 100 bases:

>100_bases
TCGATTACATTACTGAATAGCCTGTGTTGCTCTTCGTAATAAAGTTAACAATTAATAAAAATGTGTTAAGATTCACAAAA
TTTTGCAATAAGGGTAGTAA

Downstream 100 bases:

>100_bases
TGAAAATGAAACCAGCTGAACGTCGACGCGCCCGCCAATCTGCGGTACAGGCAATTTACCAATGGCAAATCACTAAACTG
AGTGCCGGTCAAATTATTGA

Product: riboflavin synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MKIIEGGLAAPQAQIAIVISRFNSFINEQLLAGAIDTLKRTGQVADDNITVVRVPGAVELPLVAKRVAASKKFDAIIALG
TVIRGGTPHFEFVAGECNKGLGQVSMDFDIPVSFGVLTTDSIEQAIERAGTKMGNKGSEAALSALEMVNVMAEFK

Sequences:

>Translated_155_residues
MKIIEGGLAAPQAQIAIVISRFNSFINEQLLAGAIDTLKRTGQVADDNITVVRVPGAVELPLVAKRVAASKKFDAIIALG
TVIRGGTPHFEFVAGECNKGLGQVSMDFDIPVSFGVLTTDSIEQAIERAGTKMGNKGSEAALSALEMVNVMAEFK
>Mature_155_residues
MKIIEGGLAAPQAQIAIVISRFNSFINEQLLAGAIDTLKRTGQVADDNITVVRVPGAVELPLVAKRVAASKKFDAIIALG
TVIRGGTPHFEFVAGECNKGLGQVSMDFDIPVSFGVLTTDSIEQAIERAGTKMGNKGSEAALSALEMVNVMAEFK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=155, Percent_Identity=67.0967741935484, Blast_Score=214, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6324429, Length=143, Percent_Identity=34.965034965035, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_PSYIN (A1SUU5)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942859.1
- ProteinModelPortal:   A1SUU5
- SMR:   A1SUU5
- STRING:   A1SUU5
- GeneID:   4625505
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1443
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- PhylomeDB:   A1SUU5
- BioCyc:   PING357804:PING_1443-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16317; Mature: 16317

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIEGGLAAPQAQIAIVISRFNSFINEQLLAGAIDTLKRTGQVADDNITVVRVPGAVEL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
PLVAKRVAASKKFDAIIALGTVIRGGTPHFEFVAGECNKGLGQVSMDFDIPVSFGVLTTD
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCCEEECEEEHH
SIEQAIERAGTKMGNKGSEAALSALEMVNVMAEFK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIIEGGLAAPQAQIAIVISRFNSFINEQLLAGAIDTLKRTGQVADDNITVVRVPGAVEL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
PLVAKRVAASKKFDAIIALGTVIRGGTPHFEFVAGECNKGLGQVSMDFDIPVSFGVLTTD
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCCEEECEEEHH
SIEQAIERAGTKMGNKGSEAALSALEMVNVMAEFK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA