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The map label for this gene is pheS [H]

Identifier: 119945139

GI number: 119945139

Start: 1722728

End: 1723744

Strand: Direct

Name: pheS [H]

Synonym: Ping_1403

Alternate gene names: 119945139

Gene position: 1722728-1723744 (Clockwise)

Preceding gene: 119945138

Following gene: 119945140

Centisome position: 37.78

GC content: 43.46

Gene sequence:

>1017_bases
ATGGTTATTGCTTGCTTCACATATGAGATTAAACAAATGCAACACCTTGATGAAATCGTTGCGAATGCGCAACAACAAAT
AGAGAAAGCCGCCGACGGCAACGAATTAGAACAAATTCGTCTACAATACCTGGGTAAAAAAGGCTTAATGACTGAGCAGA
TGAAAGGCTTAGGTAAACTGCCTCCTGCAGAAAAGCCCGCCGCAGGTCAAATGATTAATAAAGCAAAACAAGCCATTCAA
GCGGTTTTAGTTGCACGTAAGCAGGCGATGGAAGCTGAGATTTTAAATGCCCGGCTGGCTGAAGAAACCATTGATGTCAC
CTTGCCTGGACGTGGTGCAATGCTCGGCGGTGTACACCCGGTGACGCGTACCGTTGACCGTATTACTGAATTTTTTGCTG
AATTAGGTTTTGAAGTTAAAACCGGACCGGAAGTTGAAGATGCTTACCATAACTTTGATGCGTTAAATATTCCGGCACAC
CATCCTGCGCGTGCTGAACATGATACTTTTTATTTTAATCCTGAGCTGGTATTACGTACGCAAACTTCAGGTGTGCAGAT
TCGTACCATGGAAAAAGAAAACCCGCCTATTCGTATTATCTCACCGGGACGTGTTTATCGTAATGATTACGACCAGACAC
ATACGCCTATGTTCCATCAAGTTGAAGGTTTGATGATTGCAGAGGACGTAAGCTTTACTCAGCTTAAAGGCATCCTGCAT
GCATTCCTGCATAACTTTTTTGAAGAGGACTTAGAGGTACGTTTTCGTCCTTCCTATTTCCCCTTCACTGAACCTTCCGC
TGAAGTGGACGTATTAGGTAAAAATGGCTGGTTAGAAGTATTAGGCTGCGGCATGGTTCACCCGACGGTTTTACGTTCAA
TGGGGGTCGATCCGGAAAAATATTCAGGTTTTGCATTCGGTATGGGTGTTGAGCGATTAACGATGTTACGTTATGGCGTA
AATGATTTACGTTCTTTCTTCGAAAACGATCTTCGTTTCCTCAAGCAATTTAAGTAA

Upstream 100 bases:

>100_bases
AATTCCTGTTTTACGGCCTTTCATTTGGTATATGTACTAGCCAACTCTCTCTGATTTTAGTAAAATCGATTGCTATTTTT
CTTAAAATCCAATCAATACG

Downstream 100 bases:

>100_bases
GGGTTAGAATAATGAAATTTAGTGAAGCTTGGTTACGAGAATGGGTTAACCCTGAAATTACACGCGATGCATTAATCCAT
CAAATTACCATGGCAGGGCT

Product: phenylalanyl-tRNA synthetase, alpha subunit

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVIACFTYEIKQMQHLDEIVANAQQQIEKAADGNELEQIRLQYLGKKGLMTEQMKGLGKLPPAEKPAAGQMINKAKQAIQ
AVLVARKQAMEAEILNARLAEETIDVTLPGRGAMLGGVHPVTRTVDRITEFFAELGFEVKTGPEVEDAYHNFDALNIPAH
HPARAEHDTFYFNPELVLRTQTSGVQIRTMEKENPPIRIISPGRVYRNDYDQTHTPMFHQVEGLMIAEDVSFTQLKGILH
AFLHNFFEEDLEVRFRPSYFPFTEPSAEVDVLGKNGWLEVLGCGMVHPTVLRSMGVDPEKYSGFAFGMGVERLTMLRYGV
NDLRSFFENDLRFLKQFK

Sequences:

>Translated_338_residues
MVIACFTYEIKQMQHLDEIVANAQQQIEKAADGNELEQIRLQYLGKKGLMTEQMKGLGKLPPAEKPAAGQMINKAKQAIQ
AVLVARKQAMEAEILNARLAEETIDVTLPGRGAMLGGVHPVTRTVDRITEFFAELGFEVKTGPEVEDAYHNFDALNIPAH
HPARAEHDTFYFNPELVLRTQTSGVQIRTMEKENPPIRIISPGRVYRNDYDQTHTPMFHQVEGLMIAEDVSFTQLKGILH
AFLHNFFEEDLEVRFRPSYFPFTEPSAEVDVLGKNGWLEVLGCGMVHPTVLRSMGVDPEKYSGFAFGMGVERLTMLRYGV
NDLRSFFENDLRFLKQFK
>Mature_338_residues
MVIACFTYEIKQMQHLDEIVANAQQQIEKAADGNELEQIRLQYLGKKGLMTEQMKGLGKLPPAEKPAAGQMINKAKQAIQ
AVLVARKQAMEAEILNARLAEETIDVTLPGRGAMLGGVHPVTRTVDRITEFFAELGFEVKTGPEVEDAYHNFDALNIPAH
HPARAEHDTFYFNPELVLRTQTSGVQIRTMEKENPPIRIISPGRVYRNDYDQTHTPMFHQVEGLMIAEDVSFTQLKGILH
AFLHNFFEEDLEVRFRPSYFPFTEPSAEVDVLGKNGWLEVLGCGMVHPTVLRSMGVDPEKYSGFAFGMGVERLTMLRYGV
NDLRSFFENDLRFLKQFK

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=257, Percent_Identity=32.295719844358, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI5729820, Length=229, Percent_Identity=34.061135371179, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1788007, Length=327, Percent_Identity=71.8654434250764, Blast_Score=504, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI32566635, Length=241, Percent_Identity=34.8547717842324, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32563657, Length=259, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17508957, Length=259, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6321087, Length=261, Percent_Identity=31.8007662835249, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6325304, Length=315, Percent_Identity=26.984126984127, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18858079, Length=260, Percent_Identity=31.5384615384615, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137424, Length=287, Percent_Identity=28.2229965156794, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38288; Mature: 38288

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIACFTYEIKQMQHLDEIVANAQQQIEKAADGNELEQIRLQYLGKKGLMTEQMKGLGKL
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCC
PPAEKPAAGQMINKAKQAIQAVLVARKQAMEAEILNARLAEETIDVTLPGRGAMLGGVHP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCH
VTRTVDRITEFFAELGFEVKTGPEVEDAYHNFDALNIPAHHPARAEHDTFYFNPELVLRT
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEEE
QTSGVQIRTMEKENPPIRIISPGRVYRNDYDQTHTPMFHQVEGLMIAEDVSFTQLKGILH
ECCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHH
AFLHNFFEEDLEVRFRPSYFPFTEPSAEVDVLGKNGWLEVLGCGMVHPTVLRSMGVDPEK
HHHHHHHHHHHCEEECCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCHHHHHHCCCCHHH
YSGFAFGMGVERLTMLRYGVNDLRSFFENDLRFLKQFK
HCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIACFTYEIKQMQHLDEIVANAQQQIEKAADGNELEQIRLQYLGKKGLMTEQMKGLGKL
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCC
PPAEKPAAGQMINKAKQAIQAVLVARKQAMEAEILNARLAEETIDVTLPGRGAMLGGVHP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCH
VTRTVDRITEFFAELGFEVKTGPEVEDAYHNFDALNIPAHHPARAEHDTFYFNPELVLRT
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEEE
QTSGVQIRTMEKENPPIRIISPGRVYRNDYDQTHTPMFHQVEGLMIAEDVSFTQLKGILH
ECCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHH
AFLHNFFEEDLEVRFRPSYFPFTEPSAEVDVLGKNGWLEVLGCGMVHPTVLRSMGVDPEK
HHHHHHHHHHHCEEECCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCHHHHHHCCCCHHH
YSGFAFGMGVERLTMLRYGVNDLRSFFENDLRFLKQFK
HCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA