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The map label for this gene is ycgM [H]

Identifier: 119945138

GI number: 119945138

Start: 1721911

End: 1722525

Strand: Direct

Name: ycgM [H]

Synonym: Ping_1402

Alternate gene names: 119945138

Gene position: 1721911-1722525 (Clockwise)

Preceding gene: 119945137

Following gene: 119945139

Centisome position: 37.76

GC content: 38.7

Gene sequence:

>615_bases
ATGAAACAAATAAAGATTGATGGAAAATCATTTTGTCCTTCTAAAGTGGTCTGTATTGGACGTAATTATGTTGATCATAT
TAAAGAGTTAAACAATGAGATGCCAACACAAGCGGTTATTTTTGTTAAACCTAATTCCGCTATTTCTGAGCGAATAGTCA
GTAATGACATTGAACCCATTCATTATGAAGCTGAAATTTCATTTGTTATCAATGCAGGGGTGATAAGTGCAGTGGGTTTT
GGCTTAGATCTGACTAAACGCGCTTTACAATCAAGATTAAAAGCGCAGAGTTTACCCTGGGAACGTGCAAAAGCCTTTGA
TAAGTCAGCGGTATTTAGTGAATTTGTCAGTTTTAGCGGTGCCGTGCAAACCTTGTCGCTGCAGTTATTAATCAATGACA
AATTAACTCAACATGCACATTACGATTTAATGATTCATAAACCCGCCGCAATCATCTCTGAAGTCAGCGGGTTTATGAGT
TTTGAAGCGGGTGATGTGCTGATGACGGGCACCCCTAAAGGCGTGGGAGAATTATTTGAAAATGATCATTTTATCGGGCG
CATTTTTCAGGGCGATACTCTGTTGATTGAACAACATTGGATAGTTGAAGGCTAA

Upstream 100 bases:

>100_bases
GTTTGCCCAGCTGCACTGATTTCTTGTTCTGAATATGCTGTTGCGGCGCTTAACCGGGTGATGATTATTTATATTTATTA
AAATAAAAACAGGTAGTTAT

Downstream 100 bases:

>100_bases
AAATTTAAAAATTAGCTGTTGAGGTATTTTAACCATAGATTGTCTGGTTTTACCGCTAGTCATTTTTATGCACAAGTCAT
GGGGAGTTGATTTATTTAGG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKQIKIDGKSFCPSKVVCIGRNYVDHIKELNNEMPTQAVIFVKPNSAISERIVSNDIEPIHYEAEISFVINAGVISAVGF
GLDLTKRALQSRLKAQSLPWERAKAFDKSAVFSEFVSFSGAVQTLSLQLLINDKLTQHAHYDLMIHKPAAIISEVSGFMS
FEAGDVLMTGTPKGVGELFENDHFIGRIFQGDTLLIEQHWIVEG

Sequences:

>Translated_204_residues
MKQIKIDGKSFCPSKVVCIGRNYVDHIKELNNEMPTQAVIFVKPNSAISERIVSNDIEPIHYEAEISFVINAGVISAVGF
GLDLTKRALQSRLKAQSLPWERAKAFDKSAVFSEFVSFSGAVQTLSLQLLINDKLTQHAHYDLMIHKPAAIISEVSGFMS
FEAGDVLMTGTPKGVGELFENDHFIGRIFQGDTLLIEQHWIVEG
>Mature_204_residues
MKQIKIDGKSFCPSKVVCIGRNYVDHIKELNNEMPTQAVIFVKPNSAISERIVSNDIEPIHYEAEISFVINAGVISAVGF
GLDLTKRALQSRLKAQSLPWERAKAFDKSAVFSEFVSFSGAVQTLSLQLLINDKLTQHAHYDLMIHKPAAIISEVSGFMS
FEAGDVLMTGTPKGVGELFENDHFIGRIFQGDTLLIEQHWIVEG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=199, Percent_Identity=34.6733668341709, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI215422413, Length=186, Percent_Identity=34.4086021505376, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI13654274, Length=186, Percent_Identity=34.4086021505376, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI156231349, Length=203, Percent_Identity=29.5566502463054, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI40786394, Length=203, Percent_Identity=29.064039408867, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1787428, Length=199, Percent_Identity=37.1859296482412, Blast_Score=134, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17557057, Length=186, Percent_Identity=32.7956989247312, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324161, Length=238, Percent_Identity=30.672268907563, Blast_Score=114, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28571789, Length=177, Percent_Identity=30.5084745762712, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 22636; Mature: 22636

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIKIDGKSFCPSKVVCIGRNYVDHIKELNNEMPTQAVIFVKPNSAISERIVSNDIEPI
CCEEEECCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCE
HYEAEISFVINAGVISAVGFGLDLTKRALQSRLKAQSLPWERAKAFDKSAVFSEFVSFSG
EEEEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
AVQTLSLQLLINDKLTQHAHYDLMIHKPAAIISEVSGFMSFEAGDVLMTGTPKGVGELFE
CEEEEEEEEEECCCHHCCCCEEEEEECHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHC
NDHFIGRIFQGDTLLIEQHWIVEG
CCCEEEEEECCCEEEEEEEEEECC
>Mature Secondary Structure
MKQIKIDGKSFCPSKVVCIGRNYVDHIKELNNEMPTQAVIFVKPNSAISERIVSNDIEPI
CCEEEECCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCE
HYEAEISFVINAGVISAVGFGLDLTKRALQSRLKAQSLPWERAKAFDKSAVFSEFVSFSG
EEEEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
AVQTLSLQLLINDKLTQHAHYDLMIHKPAAIISEVSGFMSFEAGDVLMTGTPKGVGELFE
CEEEEEEEEEECCCHHCCCCEEEEEECHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHC
NDHFIGRIFQGDTLLIEQHWIVEG
CCCEEEEEECCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]