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The map label for this gene is zraR [H]

Identifier: 119944994

GI number: 119944994

Start: 1554793

End: 1556211

Strand: Direct

Name: zraR [H]

Synonym: Ping_1245

Alternate gene names: 119944994

Gene position: 1554793-1556211 (Clockwise)

Preceding gene: 119944991

Following gene: 119944995

Centisome position: 34.1

GC content: 44.47

Gene sequence:

>1419_bases
GTGAATGTTGGATTTAAGGAAAAGTTCAAAGATGCCCCAACCGTTCTGATTGTTGACGATGATCCAGATATCTGTTCGTT
GCTGTCTTATTTGATGAAACGAGAAGGGTATGTCGTAGAAATTGTCCACGATGGCATGGCAGCTCTTGAGCTAATGCGTA
ACCGGGTACCCGATATTATACTGACCGATTTACGAATGCCGCGAATGGATGGCTTTGAGCTACTAAAGCAGGTAAAGCTT
ATCAAACAGGATCTTCCTGTTGTGATACTCACCGCTTATGCAGGTGTTCACGGTGCTGTAGAGTCAATGAAGGAGGGGGC
TGATGATTACTTAGCTAAACCCTTTGATAACAGTAAAGTGGTGATGCTGGTTCATAGAATCCTCCTCCAGCATAACTGCT
ATGAAAGAGGCAAACTTAATGAGCAACCTATTGAGGGTGGTGTTCATGATATTGTTACGGTGATGGGACCGAGTGCTATC
ATTCACACCTTGGCCGCTCAGGTTAAGTTGGTCGCGCAATCCAATTTCAATGTCATTATTCAAGGTGCTACTGGTGTCGG
TAAAGAGGTGGTGGCCCAAGCTATTCATGCTCAGAGTCCATACGCTTCCGGCCCCTTTGTGCCGGTGGATTGTGGCGCTA
TCCCTGAAATGCTATTGGAGAGTGAACTTTTTGGCCACGAAAAGGGCGCTTTTACGGGTGCGTACCGAGCAAAGCAAGGC
AAGTTCGAAGCTGCTCGAGGTGGCACACTGTTTCTGGATGAAATTGCCAATATGCCACTGACTTCTCAGGCTAAAATTCT
ACGAGTTATGCAGGAAAAAATTATTTTTCCTGTAGGGTCAAACCAGCCTATTAAAATTGATGTGCGCCTTATAGTGGCTA
GCCATGAAAATTTAGAAGCTAAGGTCGCAGAGGGTACTTTCCGAGAAGATCTCTATTACCGATTCAATGAATTCACCATA
AAAGTACCGCTGTTGTCTGAACGAAAGGAAGATCAGATTTATCTTGCTAAGCGATTTATGAACGAGACTAACCGAGAGCT
TGGCAAAAACGTGACTCTTTCGATAGGCGCGATTAACAAAATGCAAACCTATGAATGGCGAGGAAATGTGCGCGAATTGC
GGGCGGTGATCCGCCGTGCGGTTCTCTTGGCGCAAACCGAAATCAGGGAAGAGCATCTTTCTATTAGAAGTAGGATCAGA
GATAAGGATGAATCTGGCCAGTTAAATGGCATCAATTTCACAACCGCATCTTCTCTGCCTTTGAAGGAAATCGTTCGTGA
TTGTAGTGAGAGAGTAGAAAAGAAGACATTAGCGCAGGTGCTGAGAGAAACCAATGGTAACAAGGCCAAAGCGGCCCGCA
TCCTGAAAATAGATTATAAAACGCTACTTAACAAAGTAAAGTATTATGAATTAAAATAG

Upstream 100 bases:

>100_bases
AACGAGATGATTATTCAGGATGTTATGCCGTTATGGCGATTACCCTGAAATTTTCCGATAATAAATGAAGATTAATGCTA
TTGCATAAGGACTGTTATAA

Downstream 100 bases:

>100_bases
AGAGGATATGAAAATGAAGAAAAAAACAGATGATTCAAAAAACAGTGAAAGTAACGACTTAGGTGGTGTCTTTCAGGGTT
TAGCCAAACTGGTTGAGACG

Product: two component, sigma54 specific, transcriptional regulator, Fis family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MNVGFKEKFKDAPTVLIVDDDPDICSLLSYLMKREGYVVEIVHDGMAALELMRNRVPDIILTDLRMPRMDGFELLKQVKL
IKQDLPVVILTAYAGVHGAVESMKEGADDYLAKPFDNSKVVMLVHRILLQHNCYERGKLNEQPIEGGVHDIVTVMGPSAI
IHTLAAQVKLVAQSNFNVIIQGATGVGKEVVAQAIHAQSPYASGPFVPVDCGAIPEMLLESELFGHEKGAFTGAYRAKQG
KFEAARGGTLFLDEIANMPLTSQAKILRVMQEKIIFPVGSNQPIKIDVRLIVASHENLEAKVAEGTFREDLYYRFNEFTI
KVPLLSERKEDQIYLAKRFMNETNRELGKNVTLSIGAINKMQTYEWRGNVRELRAVIRRAVLLAQTEIREEHLSIRSRIR
DKDESGQLNGINFTTASSLPLKEIVRDCSERVEKKTLAQVLRETNGNKAKAARILKIDYKTLLNKVKYYELK

Sequences:

>Translated_472_residues
MNVGFKEKFKDAPTVLIVDDDPDICSLLSYLMKREGYVVEIVHDGMAALELMRNRVPDIILTDLRMPRMDGFELLKQVKL
IKQDLPVVILTAYAGVHGAVESMKEGADDYLAKPFDNSKVVMLVHRILLQHNCYERGKLNEQPIEGGVHDIVTVMGPSAI
IHTLAAQVKLVAQSNFNVIIQGATGVGKEVVAQAIHAQSPYASGPFVPVDCGAIPEMLLESELFGHEKGAFTGAYRAKQG
KFEAARGGTLFLDEIANMPLTSQAKILRVMQEKIIFPVGSNQPIKIDVRLIVASHENLEAKVAEGTFREDLYYRFNEFTI
KVPLLSERKEDQIYLAKRFMNETNRELGKNVTLSIGAINKMQTYEWRGNVRELRAVIRRAVLLAQTEIREEHLSIRSRIR
DKDESGQLNGINFTTASSLPLKEIVRDCSERVEKKTLAQVLRETNGNKAKAARILKIDYKTLLNKVKYYELK
>Mature_472_residues
MNVGFKEKFKDAPTVLIVDDDPDICSLLSYLMKREGYVVEIVHDGMAALELMRNRVPDIILTDLRMPRMDGFELLKQVKL
IKQDLPVVILTAYAGVHGAVESMKEGADDYLAKPFDNSKVVMLVHRILLQHNCYERGKLNEQPIEGGVHDIVTVMGPSAI
IHTLAAQVKLVAQSNFNVIIQGATGVGKEVVAQAIHAQSPYASGPFVPVDCGAIPEMLLESELFGHEKGAFTGAYRAKQG
KFEAARGGTLFLDEIANMPLTSQAKILRVMQEKIIFPVGSNQPIKIDVRLIVASHENLEAKVAEGTFREDLYYRFNEFTI
KVPLLSERKEDQIYLAKRFMNETNRELGKNVTLSIGAINKMQTYEWRGNVRELRAVIRRAVLLAQTEIREEHLSIRSRIR
DKDESGQLNGINFTTASSLPLKEIVRDCSERVEKKTLAQVLRETNGNKAKAARILKIDYKTLLNKVKYYELK

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=459, Percent_Identity=41.3943355119826, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1788550, Length=462, Percent_Identity=38.5281385281385, Blast_Score=307, Evalue=9e-85,
Organism=Escherichia coli, GI1790299, Length=467, Percent_Identity=37.9014989293362, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1788905, Length=458, Percent_Identity=37.3362445414847, Blast_Score=292, Evalue=4e-80,
Organism=Escherichia coli, GI87082117, Length=341, Percent_Identity=40.4692082111437, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87082152, Length=330, Percent_Identity=40.6060606060606, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1789087, Length=409, Percent_Identity=36.919315403423, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=37.3456790123457, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1786524, Length=360, Percent_Identity=36.3888888888889, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=35.9223300970874, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1787583, Length=308, Percent_Identity=34.4155844155844, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789828, Length=232, Percent_Identity=36.2068965517241, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI87081858, Length=304, Percent_Identity=26.3157894736842, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=115, Percent_Identity=36.5217391304348, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788394, Length=137, Percent_Identity=31.3868613138686, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=32.7731092436975, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI2367329, Length=127, Percent_Identity=37.007874015748, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=105, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786784, Length=114, Percent_Identity=27.1929824561404, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=32, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=28.448275862069, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789402, Length=165, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789149, Length=128, Percent_Identity=33.59375, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1787375, Length=101, Percent_Identity=32.6732673267327, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53049; Mature: 53049

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVGFKEKFKDAPTVLIVDDDPDICSLLSYLMKREGYVVEIVHDGMAALELMRNRVPDII
CCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEE
LTDLRMPRMDGFELLKQVKLIKQDLPVVILTAYAGVHGAVESMKEGADDYLAKPFDNSKV
EECCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCHHHHCCCCCCCHH
VMLVHRILLQHNCYERGKLNEQPIEGGVHDIVTVMGPSAIIHTLAAQVKLVAQSNFNVII
HHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHEEECCCEEEE
QGATGVGKEVVAQAIHAQSPYASGPFVPVDCGAIPEMLLESELFGHEKGAFTGAYRAKQG
ECCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHCCCC
KFEAARGGTLFLDEIANMPLTSQAKILRVMQEKIIFPVGSNQPIKIDVRLIVASHENLEA
CCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEECCCCCEE
KVAEGTFREDLYYRFNEFTIKVPLLSERKEDQIYLAKRFMNETNRELGKNVTLSIGAINK
EECCCCHHHHHHEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
MQTYEWRGNVRELRAVIRRAVLLAQTEIREEHLSIRSRIRDKDESGQLNGINFTTASSLP
CEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
LKEIVRDCSERVEKKTLAQVLRETNGNKAKAARILKIDYKTLLNKVKYYELK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNVGFKEKFKDAPTVLIVDDDPDICSLLSYLMKREGYVVEIVHDGMAALELMRNRVPDII
CCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEE
LTDLRMPRMDGFELLKQVKLIKQDLPVVILTAYAGVHGAVESMKEGADDYLAKPFDNSKV
EECCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCHHHHCCCCCCCHH
VMLVHRILLQHNCYERGKLNEQPIEGGVHDIVTVMGPSAIIHTLAAQVKLVAQSNFNVII
HHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHEEECCCEEEE
QGATGVGKEVVAQAIHAQSPYASGPFVPVDCGAIPEMLLESELFGHEKGAFTGAYRAKQG
ECCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHCCCC
KFEAARGGTLFLDEIANMPLTSQAKILRVMQEKIIFPVGSNQPIKIDVRLIVASHENLEA
CCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEECCCCCEE
KVAEGTFREDLYYRFNEFTIKVPLLSERKEDQIYLAKRFMNETNRELGKNVTLSIGAINK
EECCCCHHHHHHEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
MQTYEWRGNVRELRAVIRRAVLLAQTEIREEHLSIRSRIRDKDESGQLNGINFTTASSLP
CEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
LKEIVRDCSERVEKKTLAQVLRETNGNKAKAARILKIDYKTLLNKVKYYELK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]