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The map label for this gene is hypB [H]

Identifier: 119944963

GI number: 119944963

Start: 1514937

End: 1515731

Strand: Reverse

Name: hypB [H]

Synonym: Ping_1212

Alternate gene names: 119944963

Gene position: 1515731-1514937 (Counterclockwise)

Preceding gene: 119944964

Following gene: 119944962

Centisome position: 33.24

GC content: 41.89

Gene sequence:

>795_bases
ATGTGTAAAGTTTGCGGTTGTAATCAAGCTGAAGTGACTATAGAAGGCCCACATGATCACCATCATCATAACCATCAGCA
TCAAGATATTGAACAACATTCGTCAGATATTTTAACCTCTGCAGCAAGTACTCCCAGGATGATTGAAATTGAACAAAATA
TTTTATCTAAAAATAATTATTACGCCAAGCTTAATCGCGAGCAATGGCTGGCCAATAAGATTTTCTCAATCAATCTTATC
TCCAGTCCCGGATCAGGTAAAACCACGTTATTAATTGACATTATTAAACGTATCAAAGAGCAGCACTGCATTTATGTGAT
TGAGGGGGATCAGCAAACTTCGCTTGATGCCACAAGAATCAGAGAAACCGGGGTTCAAGCGCTGCAGGTTAATACTGGCA
AAGGCTGTCACTTGGACGCGCATATGGTAGGTCATGCGGCAGTGCATCTGGGTATGCAGAAAAACGCATTTTTGTTTATC
GAAAACGTCGGCAACCTGATTTGTCCGGCGGGTTTTGATTTAGGAGAAGCGCATAAGGTGGTTATCTTATCGGTCACCGA
AGGTGAGGATAAACCCTTAAAATACCCGGAAATTTTCCATGCTGCCGATCTGATGGTGATTAACAAAATCGATCTGCTGC
CCTACGTTAATTTTGATCTGCAGCAGTGCAGTGCTTATGCAAAACAGATTAATCCTGAGATTAAAATCATCCCCCTTTCC
GCTACTTCCGGTGAGAATATGGAACAATTGAAGGATTGGTTGATTGCCGGAAAAGCGGAGCTTCAATCAGGTTAA

Upstream 100 bases:

>100_bases
CACAGGTTGGTATGAACCCTGCCCCTATTGCGGTCAACTGCTTATTAACATAACTGAAGGTGAGCAGATGAAGATTAAAT
CTTTAGAAGTGGAGAATTAA

Downstream 100 bases:

>100_bases
AGAAAATGATAATAAGAGAGCAGACTATGTGCCTAGCAATCCCTGGACAAGTTATTTCAATTAATCAATCAGCTTCGCCG
ATCACAGCAAAAGTTAATTT

Product: GTP hydrolase, accessory liganding Ni into hydrogenases, HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MCKVCGCNQAEVTIEGPHDHHHHNHQHQDIEQHSSDILTSAASTPRMIEIEQNILSKNNYYAKLNREQWLANKIFSINLI
SSPGSGKTTLLIDIIKRIKEQHCIYVIEGDQQTSLDATRIRETGVQALQVNTGKGCHLDAHMVGHAAVHLGMQKNAFLFI
ENVGNLICPAGFDLGEAHKVVILSVTEGEDKPLKYPEIFHAADLMVINKIDLLPYVNFDLQQCSAYAKQINPEIKIIPLS
ATSGENMEQLKDWLIAGKAELQSG

Sequences:

>Translated_264_residues
MCKVCGCNQAEVTIEGPHDHHHHNHQHQDIEQHSSDILTSAASTPRMIEIEQNILSKNNYYAKLNREQWLANKIFSINLI
SSPGSGKTTLLIDIIKRIKEQHCIYVIEGDQQTSLDATRIRETGVQALQVNTGKGCHLDAHMVGHAAVHLGMQKNAFLFI
ENVGNLICPAGFDLGEAHKVVILSVTEGEDKPLKYPEIFHAADLMVINKIDLLPYVNFDLQQCSAYAKQINPEIKIIPLS
ATSGENMEQLKDWLIAGKAELQSG
>Mature_264_residues
MCKVCGCNQAEVTIEGPHDHHHHNHQHQDIEQHSSDILTSAASTPRMIEIEQNILSKNNYYAKLNREQWLANKIFSINLI
SSPGSGKTTLLIDIIKRIKEQHCIYVIEGDQQTSLDATRIRETGVQALQVNTGKGCHLDAHMVGHAAVHLGMQKNAFLFI
ENVGNLICPAGFDLGEAHKVVILSVTEGEDKPLKYPEIFHAADLMVINKIDLLPYVNFDLQQCSAYAKQINPEIKIIPLS
ATSGENMEQLKDWLIAGKAELQSG

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=285, Percent_Identity=50.1754385964912, Blast_Score=279, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 29347; Mature: 29347

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKVCGCNQAEVTIEGPHDHHHHNHQHQDIEQHSSDILTSAASTPRMIEIEQNILSKNNY
CCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCE
YAKLNREQWLANKIFSINLISSPGSGKTTLLIDIIKRIKEQHCIYVIEGDQQTSLDATRI
EEEECHHHHHHHCEEEEEEECCCCCCCEEHHHHHHHHHHHCCEEEEEECCCCCCCHHHHH
RETGVQALQVNTGKGCHLDAHMVGHAAVHLGMQKNAFLFIENVGNLICPAGFDLGEAHKV
HHCCCEEEEEECCCCCEEEHHHHHHHHEEECCCCCEEEEEECCCCEECCCCCCCCCCCEE
VILSVTEGEDKPLKYPEIFHAADLMVINKIDLLPYVNFDLQQCSAYAKQINPEIKIIPLS
EEEEEECCCCCCCCCCHHHHHHCEEEEEEEECCEECCCCHHHHHHHHHHCCCCEEEEEEE
ATSGENMEQLKDWLIAGKAELQSG
CCCCCCHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MCKVCGCNQAEVTIEGPHDHHHHNHQHQDIEQHSSDILTSAASTPRMIEIEQNILSKNNY
CCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCE
YAKLNREQWLANKIFSINLISSPGSGKTTLLIDIIKRIKEQHCIYVIEGDQQTSLDATRI
EEEECHHHHHHHCEEEEEEECCCCCCCEEHHHHHHHHHHHCCEEEEEECCCCCCCHHHHH
RETGVQALQVNTGKGCHLDAHMVGHAAVHLGMQKNAFLFIENVGNLICPAGFDLGEAHKV
HHCCCEEEEEECCCCCEEEHHHHHHHHEEECCCCCEEEEEECCCCEECCCCCCCCCCCEE
VILSVTEGEDKPLKYPEIFHAADLMVINKIDLLPYVNFDLQQCSAYAKQINPEIKIIPLS
EEEEEECCCCCCCCCCHHHHHHCEEEEEEEECCEECCCCHHHHHHHHHHCCCCEEEEEEE
ATSGENMEQLKDWLIAGKAELQSG
CCCCCCHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]