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The map label for this gene is hypA

Identifier: 119944964

GI number: 119944964

Start: 1515732

End: 1516076

Strand: Reverse

Name: hypA

Synonym: Ping_1213

Alternate gene names: 119944964

Gene position: 1516076-1515732 (Counterclockwise)

Preceding gene: 119944965

Following gene: 119944963

Centisome position: 33.25

GC content: 40.29

Gene sequence:

>345_bases
ATGCATGAATTATCCATTGCAGAAAGCATTATTGAACTGCTCGAAGAACATGCCGTTACGCATAAATTTAAAAAGGTGAC
TAAAATTATATTAGAAATCGGTGTGTTGGCCGGAATAGAGAAATCGGCATTGTTTTTTTGTTTTGATGTGGCTGCGCAAA
ACAGCCTGGCTGAAGGCGCAGAACTCTTGATTGAGGATAAACTTGCTCAAGGAGTTTGCCAAAATTGCCATCTGCAGGTA
ACGACCACAGGTTGGTATGAACCCTGCCCCTATTGCGGTCAACTGCTTATTAACATAACTGAAGGTGAGCAGATGAAGAT
TAAATCTTTAGAAGTGGAGAATTAA

Upstream 100 bases:

>100_bases
GCCACGCAATTTTTAAAGAAGCTGTTGTCCTGTCAAAATCCGCAGCTGCTACTTCAGCAACTAGTGCAGCAAACAGTTCA
CAACCTGAAAGATAAAGAAA

Downstream 100 bases:

>100_bases
ATGTGTAAAGTTTGCGGTTGTAATCAAGCTGAAGTGACTATAGAAGGCCCACATGATCACCATCATCATAACCATCAGCA
TCAAGATATTGAACAACATT

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MHELSIAESIIELLEEHAVTHKFKKVTKIILEIGVLAGIEKSALFFCFDVAAQNSLAEGAELLIEDKLAQGVCQNCHLQV
TTTGWYEPCPYCGQLLINITEGEQMKIKSLEVEN

Sequences:

>Translated_114_residues
MHELSIAESIIELLEEHAVTHKFKKVTKIILEIGVLAGIEKSALFFCFDVAAQNSLAEGAELLIEDKLAQGVCQNCHLQV
TTTGWYEPCPYCGQLLINITEGEQMKIKSLEVEN
>Mature_114_residues
MHELSIAESIIELLEEHAVTHKFKKVTKIILEIGVLAGIEKSALFFCFDVAAQNSLAEGAELLIEDKLAQGVCQNCHLQV
TTTGWYEPCPYCGQLLINITEGEQMKIKSLEVEN

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789081, Length=115, Percent_Identity=33.9130434782609, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=36.283185840708, Blast_Score=80, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_PSYIN (A1SU80)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942644.1
- STRING:   A1SU80
- GeneID:   4623764
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1213
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   MHEVSLM
- PhylomeDB:   A1SU80
- BioCyc:   PING357804:PING_1213-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12662; Mature: 12662

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSIAESIIELLEEHAVTHKFKKVTKIILEIGVLAGIEKSALFFCFDVAAQNSLAEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
ELLIEDKLAQGVCQNCHLQVTTTGWYEPCPYCGQLLINITEGEQMKIKSLEVEN
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHEEEECCCCCEEEEEEEECCC
>Mature Secondary Structure
MHELSIAESIIELLEEHAVTHKFKKVTKIILEIGVLAGIEKSALFFCFDVAAQNSLAEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
ELLIEDKLAQGVCQNCHLQVTTTGWYEPCPYCGQLLINITEGEQMKIKSLEVEN
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHEEEECCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA