Click here to switch to the map view.

The map label for this gene is hupE [H]

Identifier: 119944961

GI number: 119944961

Start: 1513629

End: 1514639

Strand: Reverse

Name: hupE [H]

Synonym: Ping_1210

Alternate gene names: 119944961

Gene position: 1514639-1513629 (Counterclockwise)

Preceding gene: 119944962

Following gene: 119944960

Centisome position: 33.22

GC content: 48.66

Gene sequence:

>1011_bases
ATGGCATCAGCAAGCATTAAAATGGCGCATGGCAGCGGCGGCCGCCTTTCCAATGAACTTATTAATGAGCTGTTTTTTCG
GGCCTTTGACAATCCTATTTTAAAGCAGGCCAACGACGGGGCTTTATTAACAATGGACAGTAAGCGCTTGGCTTTCTCCA
CGGATTCCTTTGTGGTTAATCCGTATTTCTTCCCCGGAGGCAGTATTGGCGATCTTGCCATTAACGGCACGGTGAATGAC
ATTGCCATGTGCGGTGCAGTACCACGGTTTCTCTCCGCAGCCTTTATTCTCGAAGAAGGCTTGCCTATTAAGCATCTAAA
AAAAATAGTTAACAGTATGGCTGATGCTGCACGGGCGGCACAAGTGCAGATAGTGACCGGCGATACTAAAGTAGTTGAGC
GCGGCGCTGCTGATGGCATTTTTATTAATACCTCAGGAATAGGAATTATTCAACACCAGCAGCAGATAGCGCCGCAAAAC
GCACAGGCTGGCGATGTTGTTATTACGAATGGTTATATCGGTGACCATGGCATTGCCATTTTGTCACAACGCGAAGGTTT
ATCGTTCGAAACCACTATTGAATCCGACACGGCCGCTCTGCATACCCTGGTCGCCAGCATATTAGCGGCTTCTGCCAATA
TTCATGTACTACGCGACCCCACCAGAGGCGGCATTGCCGGCACCCTGAATGAAATAGCCCAGGCCAGCCAAGTGGAAATT
CGTCTTGAGGAGTATGCGATTCCAATGCGTGATTCAGTGCGCGCCGCCTGCGATCTTTTAGGACTGGATCCTTTGATTGT
CGCCAATGAAGGTAAACTGATCACCATTGTGCCCTTAGCTGACAGTGGTAAAGTATTAAAAGCAATGCAGCAGCACCCGC
TTGGCAGAGAGAGTGCCATTATCGGTCGAGTATTAAATCAACATATCGGCAAGGTGACCCTTGAAACCAGTATCGGCAGT
TTAAGAGTAGTCGATATGCCGCTGGGCGAGCAATTACCGAGGATCTGTTAA

Upstream 100 bases:

>100_bases
GATCAACAGGCGGCCTTAGAAACCCTGCAGCTTTTTGAACAATTTGAACAGCAGCAGGAATAAATCCTGCCGGCATAAAA
AACAAAAATAAGGATCAGTT

Downstream 100 bases:

>100_bases
TGGAGGATGGGTTATCAGTTAAATTGGCCAATAAAAAATGTCTTTTCCTGTGTTCTACTTTTAATGGATTAAGTCAAAAA
TTTTGGGTTAATTTCTCCTC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MASASIKMAHGSGGRLSNELINELFFRAFDNPILKQANDGALLTMDSKRLAFSTDSFVVNPYFFPGGSIGDLAINGTVND
IAMCGAVPRFLSAAFILEEGLPIKHLKKIVNSMADAARAAQVQIVTGDTKVVERGAADGIFINTSGIGIIQHQQQIAPQN
AQAGDVVITNGYIGDHGIAILSQREGLSFETTIESDTAALHTLVASILAASANIHVLRDPTRGGIAGTLNEIAQASQVEI
RLEEYAIPMRDSVRAACDLLGLDPLIVANEGKLITIVPLADSGKVLKAMQQHPLGRESAIIGRVLNQHIGKVTLETSIGS
LRVVDMPLGEQLPRIC

Sequences:

>Translated_336_residues
MASASIKMAHGSGGRLSNELINELFFRAFDNPILKQANDGALLTMDSKRLAFSTDSFVVNPYFFPGGSIGDLAINGTVND
IAMCGAVPRFLSAAFILEEGLPIKHLKKIVNSMADAARAAQVQIVTGDTKVVERGAADGIFINTSGIGIIQHQQQIAPQN
AQAGDVVITNGYIGDHGIAILSQREGLSFETTIESDTAALHTLVASILAASANIHVLRDPTRGGIAGTLNEIAQASQVEI
RLEEYAIPMRDSVRAACDLLGLDPLIVANEGKLITIVPLADSGKVLKAMQQHPLGRESAIIGRVLNQHIGKVTLETSIGS
LRVVDMPLGEQLPRIC
>Mature_335_residues
ASASIKMAHGSGGRLSNELINELFFRAFDNPILKQANDGALLTMDSKRLAFSTDSFVVNPYFFPGGSIGDLAINGTVNDI
AMCGAVPRFLSAAFILEEGLPIKHLKKIVNSMADAARAAQVQIVTGDTKVVERGAADGIFINTSGIGIIQHQQQIAPQNA
QAGDVVITNGYIGDHGIAILSQREGLSFETTIESDTAALHTLVASILAASANIHVLRDPTRGGIAGTLNEIAQASQVEIR
LEEYAIPMRDSVRAACDLLGLDPLIVANEGKLITIVPLADSGKVLKAMQQHPLGRESAIIGRVLNQHIGKVTLETSIGSL
RVVDMPLGEQLPRIC

Specific function: May be involved in the maturation of the nifE hydrogenase [H]

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=48.6646884272997, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35603; Mature: 35472

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASASIKMAHGSGGRLSNELINELFFRAFDNPILKQANDGALLTMDSKRLAFSTDSFVVN
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCEEEEECCCEEEC
PYFFPGGSIGDLAINGTVNDIAMCGAVPRFLSAAFILEEGLPIKHLKKIVNSMADAARAA
CEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHE
QVQIVTGDTKVVERGAADGIFINTSGIGIIQHQQQIAPQNAQAGDVVITNGYIGDHGIAI
EEEEEECCHHHHHCCCCCCEEEECCCCEEEECHHHCCCCCCCCCCEEEECCEECCCCEEE
LSQREGLSFETTIESDTAALHTLVASILAASANIHVLRDPTRGGIAGTLNEIAQASQVEI
EECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCHHHEEE
RLEEYAIPMRDSVRAACDLLGLDPLIVANEGKLITIVPLADSGKVLKAMQQHPLGRESAI
EEEHHCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCCCCCHHHH
IGRVLNQHIGKVTLETSIGSLRVVDMPLGEQLPRIC
HHHHHHHHHCEEEEEECCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ASASIKMAHGSGGRLSNELINELFFRAFDNPILKQANDGALLTMDSKRLAFSTDSFVVN
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCEEEEECCCEEEC
PYFFPGGSIGDLAINGTVNDIAMCGAVPRFLSAAFILEEGLPIKHLKKIVNSMADAARAA
CEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHE
QVQIVTGDTKVVERGAADGIFINTSGIGIIQHQQQIAPQNAQAGDVVITNGYIGDHGIAI
EEEEEECCHHHHHCCCCCCEEEECCCCEEEECHHHCCCCCCCCCCEEEECCEECCCCEEE
LSQREGLSFETTIESDTAALHTLVASILAASANIHVLRDPTRGGIAGTLNEIAQASQVEI
EECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCHHHEEE
RLEEYAIPMRDSVRAACDLLGLDPLIVANEGKLITIVPLADSGKVLKAMQQHPLGRESAI
EEEHHCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCCCCCHHHH
IGRVLNQHIGKVTLETSIGSLRVVDMPLGEQLPRIC
HHHHHHHHHCEEEEEECCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1526470 [H]