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The map label for this gene is mrdB [H]

Identifier: 119944890

GI number: 119944890

Start: 1421821

End: 1422921

Strand: Reverse

Name: mrdB [H]

Synonym: Ping_1134

Alternate gene names: 119944890

Gene position: 1422921-1421821 (Counterclockwise)

Preceding gene: 119944891

Following gene: 119944889

Centisome position: 31.21

GC content: 39.33

Gene sequence:

>1101_bases
ATGCTCAGCACGCAAGCTCAAAAGAGCATTTTTTATCGTTTGCACATAGATCCGCTGCTACTAATAGGATTATTTTCTTT
AATGGGGTTAAGCCTAACCATATTATATTCTGTTGCTGGTTATGAGATGTTAATCAGGCAAGTCATTCGTTTAGCCATTG
CCCTTGCCGTCATGTTTGTAATAGCGCAAATTCCCCCTGAAATTTACCAACGCTGGACACCGGCTATTTTTGTTATTATT
ATATTACTGCTAATCGCAGTGCTGGTCATTGGTCATACAGGCAAAGGCGCGCAACGCTGGTTAGACCTGGGTTTTACAAA
ATTTCAACCGTCTGAAATAATGAAACTGATTATGCCATTTATGGTCGCTTATTATATAAGCGAATACAATTTACCACCAC
GTTTAAAACAGATTTTTGTATCCTTGTTAATTGTCCTTGTCCCGACCCTCTTAATAGCAGTACAACCAGATTTAGGCACT
GCTATATTAGTCGCGTCATCGGGTGTTTTTGCACTTTTCCTTTCAGGGATTTCATGGTTGTATCTTTCAATAGCCGCGAC
CGCTTTGATCGCATTTGTCCCCGTCCTGTGGTTTTATTTAATGCATGATTATCAGCGAAGTCGTGTATTAACTCTGTTTA
ATCCTGAATCTGATCCGCTTGGCGCGGGGTATCATATTATCCAGTCCAAAATAGCGATCGGTTCAGGTGGCCTCTCGGGT
AAAGGTTGGTTACAAGGAACACAATCTCAGCTTGAATTTTTACCTGAACGCCACACTGATTTTATTTTTTCTGTTTTTTC
AGAAGAGTTTGGTTTTATCGGTATCTTAATGTTGTTAACCATTTATCTGTTTATTATTGCGCGTGGTTTATGGATAGCAA
ACAAAGCCCAAGATGCTTTCACAAAATTAGTTGCAGGCAGTATTACCCTTACTTTTTTTGTTTATGTTTTTGTAAATATT
GGCATGGTGAGTGGGTTATTACCCGTAGTAGGCGTCCCCTTGCCGTTAATAAGTTATGGAGGCACCTCAATTGTTACTTT
AATAGCCGGTTTCGGGGTGTTAATGTCTATTAATACCCATAAACGTTTTAATACAAACTGA

Upstream 100 bases:

>100_bases
GTGGTAGCAGTCACGCAGCCCCGATTGTCCGTTCTTTGTTTGATGAATATTTTAAAAATACGTCACCCTCTCCTGCTACT
CAATCGTTAGGCTTATAATA

Downstream 100 bases:

>100_bases
TAAAAAATGCGCAAATTTAAAATATCACTCATATTTCTGCTGACTATGATGCTTATTGGATGCAGCTCTCAGGATACTGC
CGACGGCCGTTATCAAATAG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLSTQAQKSIFYRLHIDPLLLIGLFSLMGLSLTILYSVAGYEMLIRQVIRLAIALAVMFVIAQIPPEIYQRWTPAIFVII
ILLLIAVLVIGHTGKGAQRWLDLGFTKFQPSEIMKLIMPFMVAYYISEYNLPPRLKQIFVSLLIVLVPTLLIAVQPDLGT
AILVASSGVFALFLSGISWLYLSIAATALIAFVPVLWFYLMHDYQRSRVLTLFNPESDPLGAGYHIIQSKIAIGSGGLSG
KGWLQGTQSQLEFLPERHTDFIFSVFSEEFGFIGILMLLTIYLFIIARGLWIANKAQDAFTKLVAGSITLTFFVYVFVNI
GMVSGLLPVVGVPLPLISYGGTSIVTLIAGFGVLMSINTHKRFNTN

Sequences:

>Translated_366_residues
MLSTQAQKSIFYRLHIDPLLLIGLFSLMGLSLTILYSVAGYEMLIRQVIRLAIALAVMFVIAQIPPEIYQRWTPAIFVII
ILLLIAVLVIGHTGKGAQRWLDLGFTKFQPSEIMKLIMPFMVAYYISEYNLPPRLKQIFVSLLIVLVPTLLIAVQPDLGT
AILVASSGVFALFLSGISWLYLSIAATALIAFVPVLWFYLMHDYQRSRVLTLFNPESDPLGAGYHIIQSKIAIGSGGLSG
KGWLQGTQSQLEFLPERHTDFIFSVFSEEFGFIGILMLLTIYLFIIARGLWIANKAQDAFTKLVAGSITLTFFVYVFVNI
GMVSGLLPVVGVPLPLISYGGTSIVTLIAGFGVLMSINTHKRFNTN
>Mature_366_residues
MLSTQAQKSIFYRLHIDPLLLIGLFSLMGLSLTILYSVAGYEMLIRQVIRLAIALAVMFVIAQIPPEIYQRWTPAIFVII
ILLLIAVLVIGHTGKGAQRWLDLGFTKFQPSEIMKLIMPFMVAYYISEYNLPPRLKQIFVSLLIVLVPTLLIAVQPDLGT
AILVASSGVFALFLSGISWLYLSIAATALIAFVPVLWFYLMHDYQRSRVLTLFNPESDPLGAGYHIIQSKIAIGSGGLSG
KGWLQGTQSQLEFLPERHTDFIFSVFSEEFGFIGILMLLTIYLFIIARGLWIANKAQDAFTKLVAGSITLTFFVYVFVNI
GMVSGLLPVVGVPLPLISYGGTSIVTLIAGFGVLMSINTHKRFNTN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=364, Percent_Identity=57.1428571428571, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1786277, Length=326, Percent_Identity=34.6625766871166, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40518; Mature: 40518

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTQAQKSIFYRLHIDPLLLIGLFSLMGLSLTILYSVAGYEMLIRQVIRLAIALAVMFV
CCCCHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQIPPEIYQRWTPAIFVIIILLLIAVLVIGHTGKGAQRWLDLGFTKFQPSEIMKLIMPF
HHHCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
MVAYYISEYNLPPRLKQIFVSLLIVLVPTLLIAVQPDLGTAILVASSGVFALFLSGISWL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
YLSIAATALIAFVPVLWFYLMHDYQRSRVLTLFNPESDPLGAGYHIIQSKIAIGSGGLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC
KGWLQGTQSQLEFLPERHTDFIFSVFSEEFGFIGILMLLTIYLFIIARGLWIANKAQDAF
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TKLVAGSITLTFFVYVFVNIGMVSGLLPVVGVPLPLISYGGTSIVTLIAGFGVLMSINTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHEEECCC
KRFNTN
CCCCCC
>Mature Secondary Structure
MLSTQAQKSIFYRLHIDPLLLIGLFSLMGLSLTILYSVAGYEMLIRQVIRLAIALAVMFV
CCCCHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQIPPEIYQRWTPAIFVIIILLLIAVLVIGHTGKGAQRWLDLGFTKFQPSEIMKLIMPF
HHHCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
MVAYYISEYNLPPRLKQIFVSLLIVLVPTLLIAVQPDLGTAILVASSGVFALFLSGISWL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
YLSIAATALIAFVPVLWFYLMHDYQRSRVLTLFNPESDPLGAGYHIIQSKIAIGSGGLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC
KGWLQGTQSQLEFLPERHTDFIFSVFSEEFGFIGILMLLTIYLFIIARGLWIANKAQDAF
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TKLVAGSITLTFFVYVFVNIGMVSGLLPVVGVPLPLISYGGTSIVTLIAGFGVLMSINTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHEEECCC
KRFNTN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]