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The map label for this gene is trpD [H]

Identifier: 119944817

GI number: 119944817

Start: 1333411

End: 1334013

Strand: Reverse

Name: trpD [H]

Synonym: Ping_1059

Alternate gene names: 119944817

Gene position: 1334013-1333411 (Counterclockwise)

Preceding gene: 119944818

Following gene: 119944816

Centisome position: 29.26

GC content: 42.45

Gene sequence:

>603_bases
ATGGAGATAACTAAAAAACAAACACTCTTTTTCCTGGATAACTTTGACTCTTTTACTTATAACCTGGTTGATCAATTTAA
GGCATTGGGTTATCCGGTAAGAATTTACCGTAATAATATACCCGCCACGCAGGTTAAAGCGCATATTGATGCTTGTGAAA
ATGATGTGGTTTTAATTCTTTCACCTGGGCCCGGCACGCCAAGTGCGGCAGGTTGCCTGATTGAATTGATCGGTTTATGC
AGAGGGCAAATTCCGATGATTGGGGTGTGCTTAGGCCACCAGGCGATTATCGAGCAGTATGGTGGCACTGTCGGTCAAGC
GGATCAAATTATGCATGGTAAATCATCGTTAATAGAACATTGCGGTGACCGAATGTTCAGCGGTTTAAGCCAGCCGCTTT
CCGTTGCCCGCTATCATTCATTAATCGGTACCTTTGTACCGGCATCGCTCGAAGTAGTAGCACATTTTAATGGCATGTGC
ATGGCCGTTTATAATGAAGCAGATAAAGTGATAGGTGTTCAATTTCATCCTGAATCTATTTTAACCTGCGAAGGTGCAAA
ATTATTAGAGAGCAGTTTAAATTTAGTCACGGGGAACAGTTAA

Upstream 100 bases:

>100_bases
GCGGAAGTATCTCGACCTGATGTGTCTTTACCTGATACCTCTTTACCTGAAACGCCCTCAACAGGCGCTTCCTCAACCTT
AGCTAATGGAGAGTAAAAAG

Downstream 100 bases:

>100_bases
ATGAGTTCATTCAACATACATGAAATTTTAGAGCAGTTATACGCCGCTAAATCACTGACCAGTGAGCAAAGCCAGGCATT
CTTTGAACGGGTTGTTCAGG

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MEITKKQTLFFLDNFDSFTYNLVDQFKALGYPVRIYRNNIPATQVKAHIDACENDVVLILSPGPGTPSAAGCLIELIGLC
RGQIPMIGVCLGHQAIIEQYGGTVGQADQIMHGKSSLIEHCGDRMFSGLSQPLSVARYHSLIGTFVPASLEVVAHFNGMC
MAVYNEADKVIGVQFHPESILTCEGAKLLESSLNLVTGNS

Sequences:

>Translated_200_residues
MEITKKQTLFFLDNFDSFTYNLVDQFKALGYPVRIYRNNIPATQVKAHIDACENDVVLILSPGPGTPSAAGCLIELIGLC
RGQIPMIGVCLGHQAIIEQYGGTVGQADQIMHGKSSLIEHCGDRMFSGLSQPLSVARYHSLIGTFVPASLEVVAHFNGMC
MAVYNEADKVIGVQFHPESILTCEGAKLLESSLNLVTGNS
>Mature_200_residues
MEITKKQTLFFLDNFDSFTYNLVDQFKALGYPVRIYRNNIPATQVKAHIDACENDVVLILSPGPGTPSAAGCLIELIGLC
RGQIPMIGVCLGHQAIIEQYGGTVGQADQIMHGKSSLIEHCGDRMFSGLSQPLSVARYHSLIGTFVPASLEVVAHFNGMC
MAVYNEADKVIGVQFHPESILTCEGAKLLESSLNLVTGNS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=185, Percent_Identity=60, Blast_Score=236, Evalue=9e-64,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=42.3280423280423, Blast_Score=142, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322638, Length=195, Percent_Identity=39.4871794871795, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281365319, Length=137, Percent_Identity=33.5766423357664, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21632; Mature: 21632

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITKKQTLFFLDNFDSFTYNLVDQFKALGYPVRIYRNNIPATQVKAHIDACENDVVLIL
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEE
SPGPGTPSAAGCLIELIGLCRGQIPMIGVCLGHQAIIEQYGGTVGQADQIMHGKSSLIEH
ECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
CGDRMFSGLSQPLSVARYHSLIGTFVPASLEVVAHFNGMCMAVYNEADKVIGVQFHPESI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCCCCEEEEEECCCCE
LTCEGAKLLESSLNLVTGNS
EEECCHHHHHHCCCEEECCC
>Mature Secondary Structure
MEITKKQTLFFLDNFDSFTYNLVDQFKALGYPVRIYRNNIPATQVKAHIDACENDVVLIL
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEE
SPGPGTPSAAGCLIELIGLCRGQIPMIGVCLGHQAIIEQYGGTVGQADQIMHGKSSLIEH
ECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
CGDRMFSGLSQPLSVARYHSLIGTFVPASLEVVAHFNGMCMAVYNEADKVIGVQFHPESI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCCCCEEEEEECCCCE
LTCEGAKLLESSLNLVTGNS
EEECCHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7038627; 6283099; 9097039; 9278503; 4594441 [H]