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The map label for this gene is hutI

Identifier: 119944790

GI number: 119944790

Start: 1302371

End: 1303582

Strand: Reverse

Name: hutI

Synonym: Ping_1032

Alternate gene names: 119944790

Gene position: 1303582-1302371 (Counterclockwise)

Preceding gene: 119944791

Following gene: 119944789

Centisome position: 28.59

GC content: 44.55

Gene sequence:

>1212_bases
ATGAATTTACTCTTAACCAATGCCAGTATTGTTACTGTGGAAACAAACGACACGGGTTACCTGATTAAACATAATCATTT
TATTAATATCATTAACGGTAAAATCGCACAGATAGGTGGAATGGCATCCTGCCCGCTTGCATCATCGGGTAAACAACTCG
ACTGTGAACATAAACTGCTTACGCCGGGGTTTATCGACTGCCATACCCACCTGGTTTTTGCCGGTAATCGTGCCAATGAA
TTTGAGCAACGCTTAACCGGTGTGCCCTATCAAGAAATTGCCCGTCAAGGCGGCGGAATCATGACGACGGTCAACGCTAC
GAGAAAAGCCACGGAAGCACAATTGTTAGAAAAAGCCCTGCAGCACCTTTCGGGGTTAATTAAAGATGGCGTTACCACGG
TTGAAATAAAATCGGGTTATGGCCTCGACCTTGAAAGTGAATTAAAAATACTGCGTGTCGCCAAACAGATTGAGCAACAG
GCAAATATTAAAGTTTCCACCACACTTCTCGCAGCGCATGCAGTCCCGCTGGAATTTAAAGATAATCCGGACCGTTATAT
TGATTATGTGTGCAATACAATTATTCCGGCAGCTGTTAAGGCACAGCTAGTCGATTATGTTGATATATTCTGTGAGGGTA
TTGGTTTTAACCTTAAGCAAACAGAACGGGTTTTTAAGTCAGCGTTATCTTTTGGTCTGGGCATCAAGGGACATACCGAG
CAGTTAAGTAATTCGGGCGGCAGCGCATTAGCCGCAAAAATGGGCGCAAGTTCTGTTGATCATCTTGAATATCTGGATGA
AACAGGCGTTAAAGCTCTTGCTGACAACGGTACGGTTGCGACCTTATTACCCGGCGCTTTTTATTTTTTAAGAGAAACAC
AATTACCGCCTGTTGAATTACTGCGCACATACAAAGTACCGATCGCATTAGCCACGGATTTTAATCCCGGCACCTCCCCT
ATTGCATCGCTTTTAATGATCATGAATATGGGCTGTACACTCTTTGGTTTAACACCGGAAGAGGCGTTACGCGGTGTTAC
TTGTCATGCGGCAAAAGCATTAGGTTTAGCCCAGCAGCGCGGTCAAATCAAAGTGGGTTTTGAAGCCGATCTGTGTCTTT
GGAATATCCAGCACCCGGCACAACTCGCCTATGAAATAGGCACCAATTTACTAATATCCCGGATCATTAACGGCGTGTTA
TGCAATGACTGA

Upstream 100 bases:

>100_bases
CAGCAGACAGCTCAAAACCACAAATTGTTAACATAATGCTTGCGCTTTATTTTTTAACTGCTAATCTAATTGTATATACA
TTTAAACAGGTGCAAATAAA

Downstream 100 bases:

>100_bases
TGTGGTTAATAATCAACGCCGGCATCAAGAAATGGCAGCGACGATATTACCGGCTGCCCGAATCATTATTAATGGAGTGT
TAAACAATGACTGATGCAGT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNLLLTNASIVTVETNDTGYLIKHNHFINIINGKIAQIGGMASCPLASSGKQLDCEHKLLTPGFIDCHTHLVFAGNRANE
FEQRLTGVPYQEIARQGGGIMTTVNATRKATEAQLLEKALQHLSGLIKDGVTTVEIKSGYGLDLESELKILRVAKQIEQQ
ANIKVSTTLLAAHAVPLEFKDNPDRYIDYVCNTIIPAAVKAQLVDYVDIFCEGIGFNLKQTERVFKSALSFGLGIKGHTE
QLSNSGGSALAAKMGASSVDHLEYLDETGVKALADNGTVATLLPGAFYFLRETQLPPVELLRTYKVPIALATDFNPGTSP
IASLLMIMNMGCTLFGLTPEEALRGVTCHAAKALGLAQQRGQIKVGFEADLCLWNIQHPAQLAYEIGTNLLISRIINGVL
CND

Sequences:

>Translated_403_residues
MNLLLTNASIVTVETNDTGYLIKHNHFINIINGKIAQIGGMASCPLASSGKQLDCEHKLLTPGFIDCHTHLVFAGNRANE
FEQRLTGVPYQEIARQGGGIMTTVNATRKATEAQLLEKALQHLSGLIKDGVTTVEIKSGYGLDLESELKILRVAKQIEQQ
ANIKVSTTLLAAHAVPLEFKDNPDRYIDYVCNTIIPAAVKAQLVDYVDIFCEGIGFNLKQTERVFKSALSFGLGIKGHTE
QLSNSGGSALAAKMGASSVDHLEYLDETGVKALADNGTVATLLPGAFYFLRETQLPPVELLRTYKVPIALATDFNPGTSP
IASLLMIMNMGCTLFGLTPEEALRGVTCHAAKALGLAQQRGQIKVGFEADLCLWNIQHPAQLAYEIGTNLLISRIINGVL
CND
>Mature_403_residues
MNLLLTNASIVTVETNDTGYLIKHNHFINIINGKIAQIGGMASCPLASSGKQLDCEHKLLTPGFIDCHTHLVFAGNRANE
FEQRLTGVPYQEIARQGGGIMTTVNATRKATEAQLLEKALQHLSGLIKDGVTTVEIKSGYGLDLESELKILRVAKQIEQQ
ANIKVSTTLLAAHAVPLEFKDNPDRYIDYVCNTIIPAAVKAQLVDYVDIFCEGIGFNLKQTERVFKSALSFGLGIKGHTE
QLSNSGGSALAAKMGASSVDHLEYLDETGVKALADNGTVATLLPGAFYFLRETQLPPVELLRTYKVPIALATDFNPGTSP
IASLLMIMNMGCTLFGLTPEEALRGVTCHAAKALGLAQQRGQIKVGFEADLCLWNIQHPAQLAYEIGTNLLISRIINGVL
CND

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=340, Percent_Identity=37.0588235294118, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17555004, Length=399, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_PSYIN (A1STQ6)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942470.1
- ProteinModelPortal:   A1STQ6
- SMR:   A1STQ6
- STRING:   A1STQ6
- GeneID:   4624175
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1032
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   PING357804:PING_1032-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43534; Mature: 43534

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: BINDING 77-77 BINDING 90-90 BINDING 140-140 BINDING 173-173 BINDING 241-241

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLLTNASIVTVETNDTGYLIKHNHFINIINGKIAQIGGMASCPLASSGKQLDCEHKLL
CCEEEECCEEEEEEECCCEEEEEECCEEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCC
TPGFIDCHTHLVFAGNRANEFEQRLTGVPYQEIARQGGGIMTTVNATRKATEAQLLEKAL
CCCEEECEEEEEEECCCHHHHHHHHCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
QHLSGLIKDGVTTVEIKSGYGLDLESELKILRVAKQIEQQANIKVSTTLLAAHAVPLEFK
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHEECEEEC
DNPDRYIDYVCNTIIPAAVKAQLVDYVDIFCEGIGFNLKQTERVFKSALSFGLGIKGHTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHH
QLSNSGGSALAAKMGASSVDHLEYLDETGVKALADNGTVATLLPGAFYFLRETQLPPVEL
HHCCCCCCCHHHHHCCCCHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHCCCCCHHHH
LRTYKVPIALATDFNPGTSPIASLLMIMNMGCTLFGLTPEEALRGVTCHAAKALGLAQQR
HHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCHHHHHHHHHHHHHC
GQIKVGFEADLCLWNIQHPAQLAYEIGTNLLISRIINGVLCND
CCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLLLTNASIVTVETNDTGYLIKHNHFINIINGKIAQIGGMASCPLASSGKQLDCEHKLL
CCEEEECCEEEEEEECCCEEEEEECCEEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCC
TPGFIDCHTHLVFAGNRANEFEQRLTGVPYQEIARQGGGIMTTVNATRKATEAQLLEKAL
CCCEEECEEEEEEECCCHHHHHHHHCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
QHLSGLIKDGVTTVEIKSGYGLDLESELKILRVAKQIEQQANIKVSTTLLAAHAVPLEFK
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHEECEEEC
DNPDRYIDYVCNTIIPAAVKAQLVDYVDIFCEGIGFNLKQTERVFKSALSFGLGIKGHTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHH
QLSNSGGSALAAKMGASSVDHLEYLDETGVKALADNGTVATLLPGAFYFLRETQLPPVEL
HHCCCCCCCHHHHHCCCCHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHCCCCCHHHH
LRTYKVPIALATDFNPGTSPIASLLMIMNMGCTLFGLTPEEALRGVTCHAAKALGLAQQR
HHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCHHHHHHHHHHHHHC
GQIKVGFEADLCLWNIQHPAQLAYEIGTNLLISRIINGVLCND
CCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA