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The map label for this gene is obgE

Identifier: 119944300

GI number: 119944300

Start: 670826

End: 671986

Strand: Direct

Name: obgE

Synonym: Ping_0527

Alternate gene names: 119944300

Gene position: 670826-671986 (Clockwise)

Preceding gene: 119944299

Following gene: 119944302

Centisome position: 14.71

GC content: 45.99

Gene sequence:

>1161_bases
ATGAAGTTTGTTGACGAAGCAAAAATAAAGGTTGATGCCGGAGATGGTGGCAACGGCTGTATCGGCTTCCGTACAGAAAA
ATATATCCCGCGTGGCGGCCCAAATGGCGGCGATGGCGGTGATGGCGGTGACGTTTACCTGCAGGCAGATGAAAATTTAA
ATACCCTGGTCGATTTTCGTTTTGTGCGTTTTTATGATGCTGAGCGTGGTGAAAATGGTCAAACACGAGACTGTACCGGA
TCCCGTGGCAAAGATAAAATTATTCAAGTACCCGTCGGAACACGCTGCCGTGATGCTGATACAGGGGAAGTTCTTGGCGA
TTTAACGCGCGATGGACAACAGCTCATGGTTGCCAAAGGTGGCTTCCACGGTTTAGGAAATGCACGTTTTAAAAGCAGTA
CTAACCGTGCCCCTCGTCAAAAGACCGATGGCACGCCAGGTGAAGTGCGTAACCTGCTTCTGGAGTTATTATTGCTTGCC
GATGTTGGCATGCTGGGTTTGCCTAATGCCGGTAAATCAACCTTTATCCGCAGTGTTTCAGCGGCAAAACCAAAAGTGGC
AGATTACCCGTTCACGACCTTAGTGCCAAATTTAGGTGTGGTCAGTATGGGTTATGGACGCAGTTTTGTGATTGCAGATA
TTCCCGGATTAATTGAAGGGGCATCTGATGGAGCGGGCCTTGGTGCACGTTTTCTGCGTCATTTAGAGCGTTGCCGTGTA
TTATTGCATACGATCGATTTATTGCCTGCCGATGGCAGTGATCCGGCAGAAAATGCACTGGTTATTATTGCAGAGCTTAA
AAAACACAGCCCTAAACTTGCCTCTAAACCGCGTTGGTTAGTCTTTAACAAAACGGACCTTCTGTTAGAAGATGAAGCTG
AATTAGTCATCGAGCGTGTTAAAGAAGCACTTGAGTGGGATGGACCTGTTTATAAAGTAGCCGCCATTTCAAAAACCGGG
ACAGATACCCTTTGTCGGGATGTTGTTGAATATTTAGAAGAGTTACCGGCTGAATTTACGCCAGAGGAAGAGCGTCAACA
GGTCGAATTCCAGTGGGATGATTATCATAAGACAGCAATAGAAGAGCTTGATGATGATAGTGATGATGATGATTGGAGTG
AAGATGATGAGATGATGGAAGTTATTTACACAAAAGAGTAA

Upstream 100 bases:

>100_bases
CACGAAGCTAGCATGTGTTTTAACCCGCATAAATGAGCAGAAAATTAATGGTTTTGGTATTATACAAGCCAACGATGGTG
TTGGTTTCTTGGAGGTTGGA

Downstream 100 bases:

>100_bases
ATTCCTATTTCCATGTCTGCTTGAAATTTAAAGCCCTGCTTTGGTTGTTCCACAGCAGGGCTTTTTGTTATCTTTAAACA
GGCTCTGGGCTTTCTAAGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKFVDEAKIKVDAGDGGNGCIGFRTEKYIPRGGPNGGDGGDGGDVYLQADENLNTLVDFRFVRFYDAERGENGQTRDCTG
SRGKDKIIQVPVGTRCRDADTGEVLGDLTRDGQQLMVAKGGFHGLGNARFKSSTNRAPRQKTDGTPGEVRNLLLELLLLA
DVGMLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSMGYGRSFVIADIPGLIEGASDGAGLGARFLRHLERCRV
LLHTIDLLPADGSDPAENALVIIAELKKHSPKLASKPRWLVFNKTDLLLEDEAELVIERVKEALEWDGPVYKVAAISKTG
TDTLCRDVVEYLEELPAEFTPEEERQQVEFQWDDYHKTAIEELDDDSDDDDWSEDDEMMEVIYTKE

Sequences:

>Translated_386_residues
MKFVDEAKIKVDAGDGGNGCIGFRTEKYIPRGGPNGGDGGDGGDVYLQADENLNTLVDFRFVRFYDAERGENGQTRDCTG
SRGKDKIIQVPVGTRCRDADTGEVLGDLTRDGQQLMVAKGGFHGLGNARFKSSTNRAPRQKTDGTPGEVRNLLLELLLLA
DVGMLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSMGYGRSFVIADIPGLIEGASDGAGLGARFLRHLERCRV
LLHTIDLLPADGSDPAENALVIIAELKKHSPKLASKPRWLVFNKTDLLLEDEAELVIERVKEALEWDGPVYKVAAISKTG
TDTLCRDVVEYLEELPAEFTPEEERQQVEFQWDDYHKTAIEELDDDSDDDDWSEDDEMMEVIYTKE
>Mature_386_residues
MKFVDEAKIKVDAGDGGNGCIGFRTEKYIPRGGPNGGDGGDGGDVYLQADENLNTLVDFRFVRFYDAERGENGQTRDCTG
SRGKDKIIQVPVGTRCRDADTGEVLGDLTRDGQQLMVAKGGFHGLGNARFKSSTNRAPRQKTDGTPGEVRNLLLELLLLA
DVGMLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSMGYGRSFVIADIPGLIEGASDGAGLGARFLRHLERCRV
LLHTIDLLPADGSDPAENALVIIAELKKHSPKLASKPRWLVFNKTDLLLEDEAELVIERVKEALEWDGPVYKVAAISKTG
TDTLCRDVVEYLEELPAEFTPEEERQQVEFQWDDYHKTAIEELDDDSDDDDWSEDDEMMEVIYTKE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=302, Percent_Identity=40.7284768211921, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI111955139, Length=271, Percent_Identity=37.2693726937269, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI111955063, Length=127, Percent_Identity=41.7322834645669, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=34.6456692913386, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789574, Length=365, Percent_Identity=67.1232876712329, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1787454, Length=127, Percent_Identity=33.0708661417323, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=335, Percent_Identity=35.5223880597015, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=28.8961038961039, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=34.375, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=186, Percent_Identity=38.7096774193548, Blast_Score=125, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=30.46875, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129375, Length=314, Percent_Identity=39.171974522293, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24585318, Length=353, Percent_Identity=33.1444759206799, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PSYIN (A1SSB6)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941980.1
- ProteinModelPortal:   A1SSB6
- SMR:   A1SSB6
- STRING:   A1SSB6
- GeneID:   4624839
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0527
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- PhylomeDB:   A1SSB6
- ProtClustDB:   PRK12298
- BioCyc:   PING357804:PING_0527-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 42401; Mature: 42401

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAKIKVDAGDGGNGCIGFRTEKYIPRGGPNGGDGGDGGDVYLQADENLNTLVDFR
CCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FVRFYDAERGENGQTRDCTGSRGKDKIIQVPVGTRCRDADTGEVLGDLTRDGQQLMVAKG
HHEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNARFKSSTNRAPRQKTDGTPGEVRNLLLELLLLADVGMLGLPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPNLGVVSMGYGRSFVIADIPGLIEGASDGAGLGARFLRHLERCRV
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHTIDLLPADGSDPAENALVIIAELKKHSPKLASKPRWLVFNKTDLLLEDEAELVIERV
HHHHHHHCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEECCCEEECCHHHHHHHHH
KEALEWDGPVYKVAAISKTGTDTLCRDVVEYLEELPAEFTPEEERQQVEFQWDDYHKTAI
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEECHHHHHHH
EELDDDSDDDDWSEDDEMMEVIYTKE
HHCCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MKFVDEAKIKVDAGDGGNGCIGFRTEKYIPRGGPNGGDGGDGGDVYLQADENLNTLVDFR
CCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FVRFYDAERGENGQTRDCTGSRGKDKIIQVPVGTRCRDADTGEVLGDLTRDGQQLMVAKG
HHEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNARFKSSTNRAPRQKTDGTPGEVRNLLLELLLLADVGMLGLPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPNLGVVSMGYGRSFVIADIPGLIEGASDGAGLGARFLRHLERCRV
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHTIDLLPADGSDPAENALVIIAELKKHSPKLASKPRWLVFNKTDLLLEDEAELVIERV
HHHHHHHCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEECCCEEECCHHHHHHHHH
KEALEWDGPVYKVAAISKTGTDTLCRDVVEYLEELPAEFTPEEERQQVEFQWDDYHKTAI
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEECHHHHHHH
EELDDDSDDDDWSEDDEMMEVIYTKE
HHCCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA