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The map label for this gene is rppH

Identifier: 119944276

GI number: 119944276

Start: 636881

End: 637426

Strand: Direct

Name: rppH

Synonym: Ping_0502

Alternate gene names: 119944276

Gene position: 636881-637426 (Clockwise)

Preceding gene: 119944273

Following gene: 119944277

Centisome position: 13.97

GC content: 40.29

Gene sequence:

>546_bases
GTGATTGATACTGACGGTTACCGTCCAAATGTAGGTATCATCATTTGTAATAATAATGCGCAGGTTTTATGGGCGAAACG
ATTTGGACAGCATTCATGGCAATTTCCTCAAGGGGGAATCAAAGAGGGGGAAACGCCTGAACAAGCCATGTATAGAGAAC
TGTACGAAGAAGTTGGTTTAAAACCTGAGCACGTTAAATTATTAGCAACTAGCCGTCATTGGTTACGTTATAAATTACCT
AAACGATTAGTTCGTTGGGACTCGCCTGATCCAGTTTGCATCGGGCAGAAACAGCGCTGGTTTTTATTACAATTGATTTC
AGATGAGCAGCAAATTGAGTTTGAGGCTTGCGGCAATCCTGAATTTGATGCTTGGCGCTGGGTAACTTATTGGTATCCTG
TTCGTCAGGTTGTATCGTTCAAATGTGAAGTTTACCGTTGTGCCCTAAAAGAATTTTCAGCTGTTGCTTTTTCGTTAATG
AAAAAAAGTTCAGACAAGAAAAGGAATAAACGGCCTCGTCGGGCATCTTTTTATAAAAAAAGATAA

Upstream 100 bases:

>100_bases
AATCTGTGAAAGAATACGGCATTAATTAAATTTTCATTCATTCATTATTATAAAAATCATAAAAACAAATAATGGATCAT
AACCTATAAAAGGCACTTTA

Downstream 100 bases:

>100_bases
CAGAGCTTTTTCTAAGAAAGGCGTTTTGTATGTTAAGTCAATTGCGGAATATAGTAGAGCAGGTCGGCAATGCAAAAAAT
TTAACTGAGGCCATGGACAT

Product: nucleotide phosphate derivative pyrophosphohydrolases, MutT/nudix family protein

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MIDTDGYRPNVGIIICNNNAQVLWAKRFGQHSWQFPQGGIKEGETPEQAMYRELYEEVGLKPEHVKLLATSRHWLRYKLP
KRLVRWDSPDPVCIGQKQRWFLLQLISDEQQIEFEACGNPEFDAWRWVTYWYPVRQVVSFKCEVYRCALKEFSAVAFSLM
KKSSDKKRNKRPRRASFYKKR

Sequences:

>Translated_181_residues
MIDTDGYRPNVGIIICNNNAQVLWAKRFGQHSWQFPQGGIKEGETPEQAMYRELYEEVGLKPEHVKLLATSRHWLRYKLP
KRLVRWDSPDPVCIGQKQRWFLLQLISDEQQIEFEACGNPEFDAWRWVTYWYPVRQVVSFKCEVYRCALKEFSAVAFSLM
KKSSDKKRNKRPRRASFYKKR
>Mature_181_residues
MIDTDGYRPNVGIIICNNNAQVLWAKRFGQHSWQFPQGGIKEGETPEQAMYRELYEEVGLKPEHVKLLATSRHWLRYKLP
KRLVRWDSPDPVCIGQKQRWFLLQLISDEQQIEFEACGNPEFDAWRWVTYWYPVRQVVSFKCEVYRCALKEFSAVAFSLM
KKSSDKKRNKRPRRASFYKKR

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=181, Percent_Identity=63.5359116022099, Blast_Score=250, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_PSYIN (A1SS92)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941956.1
- ProteinModelPortal:   A1SS92
- SMR:   A1SS92
- STRING:   A1SS92
- GeneID:   4623408
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0502
- eggNOG:   COG0494
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- PhylomeDB:   A1SS92
- BioCyc:   PING357804:PING_0502-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 21623; Mature: 21623

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTDGYRPNVGIIICNNNAQVLWAKRFGQHSWQFPQGGIKEGETPEQAMYRELYEEVGL
CCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
KPEHVKLLATSRHWLRYKLPKRLVRWDSPDPVCIGQKQRWFLLQLISDEQQIEFEACGNP
CHHHEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCEEHHHHHCCCCEEEEEECCCC
EFDAWRWVTYWYPVRQVVSFKCEVYRCALKEFSAVAFSLMKKSSDKKRNKRPRRASFYKK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC
R
C
>Mature Secondary Structure
MIDTDGYRPNVGIIICNNNAQVLWAKRFGQHSWQFPQGGIKEGETPEQAMYRELYEEVGL
CCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
KPEHVKLLATSRHWLRYKLPKRLVRWDSPDPVCIGQKQRWFLLQLISDEQQIEFEACGNP
CHHHEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCCCEEHHHHHCCCCEEEEEECCCC
EFDAWRWVTYWYPVRQVVSFKCEVYRCALKEFSAVAFSLMKKSSDKKRNKRPRRASFYKK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA