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The map label for this gene is ubiB [H]

Identifier: 119944106

GI number: 119944106

Start: 420083

End: 421723

Strand: Reverse

Name: ubiB [H]

Synonym: Ping_0321

Alternate gene names: 119944106

Gene position: 421723-420083 (Counterclockwise)

Preceding gene: 119944107

Following gene: 119944105

Centisome position: 9.25

GC content: 39.73

Gene sequence:

>1641_bases
ATGATAAAAATAAAAGAACTCACCCGCCTTTATCAAATCAATAAAACAGTAATTGAATATGGTTTAATAGAACTGCTCCC
TAAAGAGCATGTGCCATTAGCCTATCGTTTTATGTGTGCTTGTCTTTTTTGGATTAGCAACAAACATCAAGGTATGAGTT
TACCCGAAAGATTACGTTTAAGTTTACAGTCGCTGGGGCCAATTTATATTAAGCTTGGGCAAATGTTGTCCACCCGACGT
GATTTATTACCCCCCATTTACGCAGATCAACTGGCCTATCTTCAGGATAATGTTCCTCCTTTTTGTGGTGAACAGGCGAT
TGAACAGATAGAAAAATCCTTTAATAAGCCGATTGACAGCATCTTTGATGACTTTGATAAAGTCGCACTTGCCTCAGCCT
CTATTGCCCAGGTGCACACGGCAACACTAAAAGAAGATGGTCGAGCCGTTGTGGTTAAAGTAACCCGCCCCGGCATTGAA
AAAAGAATTCAGGCAGATTTACAGCTAATGAAGTGGTTAGCTTCTTTGATGCAGCGGTTTTTAAAAGAAGCGGAACGTCT
GCGTCCGGTCGAAGTGATACATGAATATGAAAAAACTATTATTGATGAAATAGACCTGATGCGCGAAGGCGCGAATACCA
TTCAATTACGGCGTAATTTTTTAAATTCCAAGCTACTTTATGTACCTGAAATATACCCGAATTACTGCACTAAAAACGCG
TTAGTCATGGAAAGAATTTATGGTATTCCTGTTTCTGATACCAACGCATTACAAGCACAAAATACAAATCTTAAGTTACT
GGCTGAACGCGGAGTGGAAACTTTCTTCACTCAGGTTTTCCGGGACAGCTTTTTCCATGCGGATATGCACCCGGGCAATG
TATTTGTCTCCTATGAACACCCGGAAGATCCTCTCTGGATAGGTATCGATTGTGGTATTATGGGCACGCTCAATAAAGAA
GATAAACGCTACCTTGCAGAAAACTTCCTAGCCTTTTTCAATCGAGATTATCGCCAGGTTGCACAACTTCATGTTGATTC
TGGTTGGGTTCCGGCAGATACACCCGTTGAAGAATTTGAATTTTCCATTCGCGCAGTATGTGAACCTATTTTTGAAAAAC
CGCTTGCAGAAATATCCTTTGCGCAGGTGTTAATTAACTTATTTAATACCGCGCGCCGCTATAATATGAAAGTGCAACCG
CAACTGGTTTTATTGCAAAAAACATTGTTTTATGTCGAAGGATTAGGACGGCAATTATACCCGCAACTGGACTTATGGGA
TACCGCAAAACCTTTTTTAGAAAATTGGATGAAAGAGCAGGTTAGTCCAAAAACCTTATTTAAATCAATCAGCCAAAAAG
CGCCTTTTTGGCTCGAGAAGTTACCGGAATTGCCTGAGCTTGTTTACTACAATTTATCGCAGGCTAAATCACAGAATAAG
CAACTTATTTTATTAGCTGAATCTTTTAATAAACAACAAAAAAATAACCGCAAAAGTTATTTTTATATTGCAGCGGCTAT
CTCTCTGAGTTTAATTTCGGCACTGGCTTATCTGCAAACAGATAAAAACCTTACCTTATTAGCGGGTATCCCCGGTATTT
TTGCCTGGTTACTTGCGTGGCGCTATACCAATAAGGTATAA

Upstream 100 bases:

>100_bases
TTTGTGAACAGGTAAATGATATCAAGAAGCAGACAGATACCTTAGAAAAACGTCTTCAGCTATGCTTTGCCAGCAGCAAC
AAGTTAACGCGGAATATCCG

Downstream 100 bases:

>100_bases
AGTTTACTATTAATAATGACAAACAATTAACTGAACGATTAAAGAAGGAAATAAATTATGGGCGGCATTGGTATTTGGCA
GTTAGCTATTATCACAGTAA

Product: 2-polyprenylphenol 6-hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MIKIKELTRLYQINKTVIEYGLIELLPKEHVPLAYRFMCACLFWISNKHQGMSLPERLRLSLQSLGPIYIKLGQMLSTRR
DLLPPIYADQLAYLQDNVPPFCGEQAIEQIEKSFNKPIDSIFDDFDKVALASASIAQVHTATLKEDGRAVVVKVTRPGIE
KRIQADLQLMKWLASLMQRFLKEAERLRPVEVIHEYEKTIIDEIDLMREGANTIQLRRNFLNSKLLYVPEIYPNYCTKNA
LVMERIYGIPVSDTNALQAQNTNLKLLAERGVETFFTQVFRDSFFHADMHPGNVFVSYEHPEDPLWIGIDCGIMGTLNKE
DKRYLAENFLAFFNRDYRQVAQLHVDSGWVPADTPVEEFEFSIRAVCEPIFEKPLAEISFAQVLINLFNTARRYNMKVQP
QLVLLQKTLFYVEGLGRQLYPQLDLWDTAKPFLENWMKEQVSPKTLFKSISQKAPFWLEKLPELPELVYYNLSQAKSQNK
QLILLAESFNKQQKNNRKSYFYIAAAISLSLISALAYLQTDKNLTLLAGIPGIFAWLLAWRYTNKV

Sequences:

>Translated_546_residues
MIKIKELTRLYQINKTVIEYGLIELLPKEHVPLAYRFMCACLFWISNKHQGMSLPERLRLSLQSLGPIYIKLGQMLSTRR
DLLPPIYADQLAYLQDNVPPFCGEQAIEQIEKSFNKPIDSIFDDFDKVALASASIAQVHTATLKEDGRAVVVKVTRPGIE
KRIQADLQLMKWLASLMQRFLKEAERLRPVEVIHEYEKTIIDEIDLMREGANTIQLRRNFLNSKLLYVPEIYPNYCTKNA
LVMERIYGIPVSDTNALQAQNTNLKLLAERGVETFFTQVFRDSFFHADMHPGNVFVSYEHPEDPLWIGIDCGIMGTLNKE
DKRYLAENFLAFFNRDYRQVAQLHVDSGWVPADTPVEEFEFSIRAVCEPIFEKPLAEISFAQVLINLFNTARRYNMKVQP
QLVLLQKTLFYVEGLGRQLYPQLDLWDTAKPFLENWMKEQVSPKTLFKSISQKAPFWLEKLPELPELVYYNLSQAKSQNK
QLILLAESFNKQQKNNRKSYFYIAAAISLSLISALAYLQTDKNLTLLAGIPGIFAWLLAWRYTNKV
>Mature_546_residues
MIKIKELTRLYQINKTVIEYGLIELLPKEHVPLAYRFMCACLFWISNKHQGMSLPERLRLSLQSLGPIYIKLGQMLSTRR
DLLPPIYADQLAYLQDNVPPFCGEQAIEQIEKSFNKPIDSIFDDFDKVALASASIAQVHTATLKEDGRAVVVKVTRPGIE
KRIQADLQLMKWLASLMQRFLKEAERLRPVEVIHEYEKTIIDEIDLMREGANTIQLRRNFLNSKLLYVPEIYPNYCTKNA
LVMERIYGIPVSDTNALQAQNTNLKLLAERGVETFFTQVFRDSFFHADMHPGNVFVSYEHPEDPLWIGIDCGIMGTLNKE
DKRYLAENFLAFFNRDYRQVAQLHVDSGWVPADTPVEEFEFSIRAVCEPIFEKPLAEISFAQVLINLFNTARRYNMKVQP
QLVLLQKTLFYVEGLGRQLYPQLDLWDTAKPFLENWMKEQVSPKTLFKSISQKAPFWLEKLPELPELVYYNLSQAKSQNK
QLILLAESFNKQQKNNRKSYFYIAAAISLSLISALAYLQTDKNLTLLAGIPGIFAWLLAWRYTNKV

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=233, Percent_Identity=30.9012875536481, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI41393593, Length=277, Percent_Identity=28.8808664259928, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI32261307, Length=313, Percent_Identity=25.8785942492013, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI217035081, Length=202, Percent_Identity=30.1980198019802, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI34147522, Length=213, Percent_Identity=29.5774647887324, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367309, Length=542, Percent_Identity=61.2546125461255, Blast_Score=680, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559152, Length=283, Percent_Identity=26.5017667844523, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17555620, Length=472, Percent_Identity=23.3050847457627, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI32565180, Length=260, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325148, Length=439, Percent_Identity=22.7790432801822, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6323282, Length=254, Percent_Identity=27.1653543307087, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6321319, Length=204, Percent_Identity=26.9607843137255, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI22024280, Length=276, Percent_Identity=28.2608695652174, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24662575, Length=241, Percent_Identity=29.8755186721992, Blast_Score=115, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63199; Mature: 63199

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIKELTRLYQINKTVIEYGLIELLPKEHVPLAYRFMCACLFWISNKHQGMSLPERLRL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SLQSLGPIYIKLGQMLSTRRDLLPPIYADQLAYLQDNVPPFCGEQAIEQIEKSFNKPIDS
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
IFDDFDKVALASASIAQVHTATLKEDGRAVVVKVTRPGIEKRIQADLQLMKWLASLMQRF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LKEAERLRPVEVIHEYEKTIIDEIDLMREGANTIQLRRNFLNSKLLYVPEIYPNYCTKNA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCHHCCHH
LVMERIYGIPVSDTNALQAQNTNLKLLAERGVETFFTQVFRDSFFHADMHPGNVFVSYEH
HHHHHHHCCCCCCCCCCEECCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
PEDPLWIGIDCGIMGTLNKEDKRYLAENFLAFFNRDYRQVAQLHVDSGWVPADTPVEEFE
CCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
FSIRAVCEPIFEKPLAEISFAQVLINLFNTARRYNMKVQPQLVLLQKTLFYVEGLGRQLY
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHC
PQLDLWDTAKPFLENWMKEQVSPKTLFKSISQKAPFWLEKLPELPELVYYNLSQAKSQNK
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHCHHHHCCCCC
QLILLAESFNKQQKNNRKSYFYIAAAISLSLISALAYLQTDKNLTLLAGIPGIFAWLLAW
EEEEEEHHCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
RYTNKV
HHHCCC
>Mature Secondary Structure
MIKIKELTRLYQINKTVIEYGLIELLPKEHVPLAYRFMCACLFWISNKHQGMSLPERLRL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SLQSLGPIYIKLGQMLSTRRDLLPPIYADQLAYLQDNVPPFCGEQAIEQIEKSFNKPIDS
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
IFDDFDKVALASASIAQVHTATLKEDGRAVVVKVTRPGIEKRIQADLQLMKWLASLMQRF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LKEAERLRPVEVIHEYEKTIIDEIDLMREGANTIQLRRNFLNSKLLYVPEIYPNYCTKNA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCHHCCHH
LVMERIYGIPVSDTNALQAQNTNLKLLAERGVETFFTQVFRDSFFHADMHPGNVFVSYEH
HHHHHHHCCCCCCCCCCEECCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
PEDPLWIGIDCGIMGTLNKEDKRYLAENFLAFFNRDYRQVAQLHVDSGWVPADTPVEEFE
CCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
FSIRAVCEPIFEKPLAEISFAQVLINLFNTARRYNMKVQPQLVLLQKTLFYVEGLGRQLY
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHC
PQLDLWDTAKPFLENWMKEQVSPKTLFKSISQKAPFWLEKLPELPELVYYNLSQAKSQNK
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHCHHHHCCCCC
QLILLAESFNKQQKNNRKSYFYIAAAISLSLISALAYLQTDKNLTLLAGIPGIFAWLLAW
EEEEEEHHCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
RYTNKV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA