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The map label for this gene is yhdG [H]

Identifier: 119944063

GI number: 119944063

Start: 363314

End: 364705

Strand: Direct

Name: yhdG [H]

Synonym: Ping_0278

Alternate gene names: 119944063

Gene position: 363314-364705 (Clockwise)

Preceding gene: 119944062

Following gene: 119944069

Centisome position: 7.97

GC content: 46.34

Gene sequence:

>1392_bases
ATGTCAAATAATGAAGAGTACCTTGCTCAAAGGCAATTAAAAAAAGGGGCTGCAGGCTGGATTTTGCTTGCGGGTCTTGG
GATTTCATACGTTATCTCGGGTGATTTTGCGGGATGGAATTTTGGCATCGCTCAAGCAGGATGGGGAGGATTTGTGATTG
CCGCAGTGTTGATGGGGATTATGTACTTAACCTTAGTATTATCTCTTGCTGAAATGTCGGCGGCCATTCCTGCGGCAGGT
GGTGGTTACAGTTTTGCTCGTCAAGCGATCGGGCCTGCTGGTGGTTACCTTACCGGACTTGCGGTATTAATTGAATATAC
ACTCGCCCCGGCTGCTATTGTTATTTTTATCGGCTCTGCCGTTAATGAGTTGGTCGGAATTGACGGGCCAATAGTCTACG
CTCTGTTTTACCTGATTTTTGTGGGTATTCATATTTTTGGTACGGGTGAAGCCCTGAAAGTAATGATGGTGATCAGCGGA
CTGGCTGTTTTAGCTATTATTGCAACGGCCGTTGTATTACTGCCCGAATTCGATGCGGCGCGTCTGTTTGATATCGAACC
TGCTCTCAATGGAACAGAGTTTCTGCCAATGGGCTATTACGGCGTGTGGGCAGCCCTGCCCTTTGCTATGTGGTTGTTCC
TTGCGGTCGAAGGGGTGCCTTTAGCGGCGGAAGAAGCAAAAGATCCGGCCAAAGATGTGCCCAAAGGCATTATTGCTGCG
ATAATTTTCCTTTTGTTTACTGCGGTTCTGGTTGTCGTTCTGGTGACCGGTGCTGCCGGTGCGCAAGTGACTGGTGAAAG
TGCCGTTCCACTAGTGGATGCGCTAAATATGACCGGCCATAATAATGTTGCCACTATGGTTAATATATTGGGTCTGGCAG
GATTGGTAGCCTCGTTTTTCTCTATTATTTACGGTTACAGCCGCTTAGTTTTTGCACTATCCAGAGCTGGATATTTACCG
CAAAGATTATCATTAACCAGCAAGCGAAAAGTACCAGTACGTTCACTGGTCTATCCGGGTATTTTGGGATTCCTTATTTC
ATTGACCGGTGAAGGTGATTTAATACTGTCAATGGCAGTTGTTGGCGCTACCGTATCCTATGCGATGATGTCTGGAAGCC
ACATTCTTCTTCGTATCAAGCAGCCGGAACTTAAACGTCCCTATAAAACACCGGGTGGTATTGTGACTTCCGGCATCTCT
TTTGTGCTGTCTTTAGTTGCACTGACTGGCGTCTATGCCTATGACGTTCGTGCATTCCTGTTTACTCTGGTGCTCTTTAT
TGTTGGTATGGCTTATTATTTCTTTATTGGTCGTAAAAACTTGGTTGCAGCAACCGCTGAAGAAGAGTTTGCTTTACTGT
CTCAAGCAGAAGACGAGCTTGTATCAGCTTAA

Upstream 100 bases:

>100_bases
GGGTGTGAGTTTGAAAGATCGCTCTGAAGATCTGCAGCTTGAAAGTACCACAACACAACAATTTTGTTTAACTATCTAGT
CGTTACTAAAAGGAAATATT

Downstream 100 bases:

>100_bases
TGCAGTATTTTATGCAAAATCTGTCTTAAAGCGGGCAGGTTTGACTCTTTAAATAATTAAAATAAGAAGACAATAGCCCG
CTTACTTTTTTGTTGTGACG

Product: ethanolamine transproter

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSNNEEYLAQRQLKKGAAGWILLAGLGISYVISGDFAGWNFGIAQAGWGGFVIAAVLMGIMYLTLVLSLAEMSAAIPAAG
GGYSFARQAIGPAGGYLTGLAVLIEYTLAPAAIVIFIGSAVNELVGIDGPIVYALFYLIFVGIHIFGTGEALKVMMVISG
LAVLAIIATAVVLLPEFDAARLFDIEPALNGTEFLPMGYYGVWAALPFAMWLFLAVEGVPLAAEEAKDPAKDVPKGIIAA
IIFLLFTAVLVVVLVTGAAGAQVTGESAVPLVDALNMTGHNNVATMVNILGLAGLVASFFSIIYGYSRLVFALSRAGYLP
QRLSLTSKRKVPVRSLVYPGILGFLISLTGEGDLILSMAVVGATVSYAMMSGSHILLRIKQPELKRPYKTPGGIVTSGIS
FVLSLVALTGVYAYDVRAFLFTLVLFIVGMAYYFFIGRKNLVAATAEEEFALLSQAEDELVSA

Sequences:

>Translated_463_residues
MSNNEEYLAQRQLKKGAAGWILLAGLGISYVISGDFAGWNFGIAQAGWGGFVIAAVLMGIMYLTLVLSLAEMSAAIPAAG
GGYSFARQAIGPAGGYLTGLAVLIEYTLAPAAIVIFIGSAVNELVGIDGPIVYALFYLIFVGIHIFGTGEALKVMMVISG
LAVLAIIATAVVLLPEFDAARLFDIEPALNGTEFLPMGYYGVWAALPFAMWLFLAVEGVPLAAEEAKDPAKDVPKGIIAA
IIFLLFTAVLVVVLVTGAAGAQVTGESAVPLVDALNMTGHNNVATMVNILGLAGLVASFFSIIYGYSRLVFALSRAGYLP
QRLSLTSKRKVPVRSLVYPGILGFLISLTGEGDLILSMAVVGATVSYAMMSGSHILLRIKQPELKRPYKTPGGIVTSGIS
FVLSLVALTGVYAYDVRAFLFTLVLFIVGMAYYFFIGRKNLVAATAEEEFALLSQAEDELVSA
>Mature_462_residues
SNNEEYLAQRQLKKGAAGWILLAGLGISYVISGDFAGWNFGIAQAGWGGFVIAAVLMGIMYLTLVLSLAEMSAAIPAAGG
GYSFARQAIGPAGGYLTGLAVLIEYTLAPAAIVIFIGSAVNELVGIDGPIVYALFYLIFVGIHIFGTGEALKVMMVISGL
AVLAIIATAVVLLPEFDAARLFDIEPALNGTEFLPMGYYGVWAALPFAMWLFLAVEGVPLAAEEAKDPAKDVPKGIIAAI
IFLLFTAVLVVVLVTGAAGAQVTGESAVPLVDALNMTGHNNVATMVNILGLAGLVASFFSIIYGYSRLVFALSRAGYLPQ
RLSLTSKRKVPVRSLVYPGILGFLISLTGEGDLILSMAVVGATVSYAMMSGSHILLRIKQPELKRPYKTPGGIVTSGISF
VLSLVALTGVYAYDVRAFLFTLVLFIVGMAYYFFIGRKNLVAATAEEEFALLSQAEDELVSA

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of D-Alanine, D-Serine And Glycine. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=379, Percent_Identity=21.3720316622691, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1790653, Length=384, Percent_Identity=26.0416666666667, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786302, Length=391, Percent_Identity=25.3196930946292, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786602, Length=394, Percent_Identity=23.6040609137056, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786789, Length=332, Percent_Identity=27.1084337349398, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367353, Length=412, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=358, Percent_Identity=22.3463687150838, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321629, Length=403, Percent_Identity=24.0694789081886, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322892, Length=331, Percent_Identity=25.0755287009063, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221512776, Length=370, Percent_Identity=22.972972972973, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24666159, Length=370, Percent_Identity=22.972972972973, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24668806, Length=392, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356285, Length=392, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24668802, Length=392, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI161077963, Length=332, Percent_Identity=23.1927710843373, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331183, Length=374, Percent_Identity=25.9358288770053, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17647653, Length=374, Percent_Identity=25.9358288770053, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24664379, Length=374, Percent_Identity=25.9358288770053, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48768; Mature: 48637

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNEEYLAQRQLKKGAAGWILLAGLGISYVISGDFAGWNFGIAQAGWGGFVIAAVLMGI
CCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
MYLTLVLSLAEMSAAIPAAGGGYSFARQAIGPAGGYLTGLAVLIEYTLAPAAIVIFIGSA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNELVGIDGPIVYALFYLIFVGIHIFGTGEALKVMMVISGLAVLAIIATAVVLLPEFDAA
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLFDIEPALNGTEFLPMGYYGVWAALPFAMWLFLAVEGVPLAAEEAKDPAKDVPKGIIAA
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHH
IIFLLFTAVLVVVLVTGAAGAQVTGESAVPLVDALNMTGHNNVATMVNILGLAGLVASFF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SIIYGYSRLVFALSRAGYLPQRLSLTSKRKVPVRSLVYPGILGFLISLTGEGDLILSMAV
HHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VGATVSYAMMSGSHILLRIKQPELKRPYKTPGGIVTSGISFVLSLVALTGVYAYDVRAFL
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTLVLFIVGMAYYFFIGRKNLVAATAEEEFALLSQAEDELVSA
HHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNNEEYLAQRQLKKGAAGWILLAGLGISYVISGDFAGWNFGIAQAGWGGFVIAAVLMGI
CCCHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
MYLTLVLSLAEMSAAIPAAGGGYSFARQAIGPAGGYLTGLAVLIEYTLAPAAIVIFIGSA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNELVGIDGPIVYALFYLIFVGIHIFGTGEALKVMMVISGLAVLAIIATAVVLLPEFDAA
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLFDIEPALNGTEFLPMGYYGVWAALPFAMWLFLAVEGVPLAAEEAKDPAKDVPKGIIAA
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHH
IIFLLFTAVLVVVLVTGAAGAQVTGESAVPLVDALNMTGHNNVATMVNILGLAGLVASFF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SIIYGYSRLVFALSRAGYLPQRLSLTSKRKVPVRSLVYPGILGFLISLTGEGDLILSMAV
HHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VGATVSYAMMSGSHILLRIKQPELKRPYKTPGGIVTSGISFVLSLVALTGVYAYDVRAFL
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTLVLFIVGMAYYFFIGRKNLVAATAEEEFALLSQAEDELVSA
HHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]