Click here to switch to the map view.

The map label for this gene is eutR [H]

Identifier: 119944060

GI number: 119944060

Start: 359814

End: 360869

Strand: Reverse

Name: eutR [H]

Synonym: Ping_0275

Alternate gene names: 119944060

Gene position: 360869-359814 (Counterclockwise)

Preceding gene: 119944064

Following gene: 119944054

Centisome position: 7.91

GC content: 40.53

Gene sequence:

>1056_bases
ATGCACTTTGTACAACAGCACCATGATAGATATGCAATTGCATTGGAAAGGTGCAAGTCATTCACTTTTGACGTTAATCA
GCAGGCTGAAAGCCTGATTAAATGGGAGCAGCGCTATAACCAGCACAGTAGTGGCCGGTTTAGCGGCTATTTGGATGAAT
TAAAATTAGGCGGGATACATCTTTTTGAGGAGTTTACAAACCAGACACTGCTGCAACAATGCTGCGTAAAGGAAAACAGT
CTATGGATTGGCTTTTCTCTTCAGGCACAAAGGCCAAAAATAAATAATAATAAGATTGCTGCCGGGCAGTTAATGATGAG
GCCTTCCGGGGTTGATTTTGAGTTAATGACACCACAAGATTTTCATATTTTTGGATTAGTGCTAGATGGAAAAAGCTTGC
AGGATGAAATGGTTGAATTTGATGCTGAGCGCTGGCAGAGCCAGAAAAATAAAATATTGGTGTCTGAACCAAATCACTAC
ATGATTTATGAGCTGGCAAAATTGATTCAGTTACTGCTTGGCAATAACCATTATGCAGCTTTTCAAAACAGGCCATCAGA
TGAAAGCAATCGGTCGAGGTTAAACAAGTTAATGCCGCTGATACTCTCTAGAATAGCGGATCTATTAGCACAAATAGAGT
CAGGCGTTAAGGAATTACAAGTCCAGCCTCAAACCAAGCAAAAAGTAATTTCAGCAGTCAGTCGCTATATTAAACAAACC
AATCGCTACCCACTTACCATCACAGAGTTATGCAAAATCACCCATGTCAGCAGAAGAGCGCTGCACTATTGCTTTGAGCA
GGGACTCGGTGTGTCACCAATTCAGTATATAAGGGATTGCCGGCTCAATGAGATAAGACGTATTTTATTAAGAGATGAAA
CAGAGGTTATTATTTCTGATCTGGCGCTTGATTTTGGCTTTTTTCATATCAGTACATTTAACGCGCATTACAAGCAGTTG
TTCGAGGAAACACCAACACAAACAATACAACGGTCAGCTAACTATAAAAATGCGATAATCAGCTATCCTAAAGCAGGAAC
AGATGCCAGAAGCTAG

Upstream 100 bases:

>100_bases
GTGAATAACGTCATTGTGCAAATCTTAAAAATAGTTTTAAAACAGATAGTTAGCTAAACCATGACTCAAAGTGATGGATC
AATATGGAGCACTAAAAATA

Downstream 100 bases:

>100_bases
AATAATAGATGATCTCCGAGAACAGTTTGACCATTCACAAAAATCATCACCGCAGATAATCACAGCTTTAAAGTAACGAG
TATTAGATAAAGGAGAAAAG

Product: DNA-binding helix-turn-helix domain-containing transcriptional regulator protein

Products: NA

Alternate protein names: Ethanolamine operon regulatory protein [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MHFVQQHHDRYAIALERCKSFTFDVNQQAESLIKWEQRYNQHSSGRFSGYLDELKLGGIHLFEEFTNQTLLQQCCVKENS
LWIGFSLQAQRPKINNNKIAAGQLMMRPSGVDFELMTPQDFHIFGLVLDGKSLQDEMVEFDAERWQSQKNKILVSEPNHY
MIYELAKLIQLLLGNNHYAAFQNRPSDESNRSRLNKLMPLILSRIADLLAQIESGVKELQVQPQTKQKVISAVSRYIKQT
NRYPLTITELCKITHVSRRALHYCFEQGLGVSPIQYIRDCRLNEIRRILLRDETEVIISDLALDFGFFHISTFNAHYKQL
FEETPTQTIQRSANYKNAIISYPKAGTDARS

Sequences:

>Translated_351_residues
MHFVQQHHDRYAIALERCKSFTFDVNQQAESLIKWEQRYNQHSSGRFSGYLDELKLGGIHLFEEFTNQTLLQQCCVKENS
LWIGFSLQAQRPKINNNKIAAGQLMMRPSGVDFELMTPQDFHIFGLVLDGKSLQDEMVEFDAERWQSQKNKILVSEPNHY
MIYELAKLIQLLLGNNHYAAFQNRPSDESNRSRLNKLMPLILSRIADLLAQIESGVKELQVQPQTKQKVISAVSRYIKQT
NRYPLTITELCKITHVSRRALHYCFEQGLGVSPIQYIRDCRLNEIRRILLRDETEVIISDLALDFGFFHISTFNAHYKQL
FEETPTQTIQRSANYKNAIISYPKAGTDARS
>Mature_351_residues
MHFVQQHHDRYAIALERCKSFTFDVNQQAESLIKWEQRYNQHSSGRFSGYLDELKLGGIHLFEEFTNQTLLQQCCVKENS
LWIGFSLQAQRPKINNNKIAAGQLMMRPSGVDFELMTPQDFHIFGLVLDGKSLQDEMVEFDAERWQSQKNKILVSEPNHY
MIYELAKLIQLLLGNNHYAAFQNRPSDESNRSRLNKLMPLILSRIADLLAQIESGVKELQVQPQTKQKVISAVSRYIKQT
NRYPLTITELCKITHVSRRALHYCFEQGLGVSPIQYIRDCRLNEIRRILLRDETEVIISDLALDFGFFHISTFNAHYKQL
FEETPTQTIQRSANYKNAIISYPKAGTDARS

Specific function: Activates the transcription of the eut operon. Also positively regulates its own transcription. Probably binds ethanolamine and vitamin B12 as effectors [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788778, Length=314, Percent_Identity=28.0254777070064, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 40764; Mature: 40764

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFVQQHHDRYAIALERCKSFTFDVNQQAESLIKWEQRYNQHSSGRFSGYLDELKLGGIH
CCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHH
LFEEFTNQTLLQQCCVKENSLWIGFSLQAQRPKINNNKIAAGQLMMRPSGVDFELMTPQD
HHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCEEECEEEECCCCCCEEEECCCC
FHIFGLVLDGKSLQDEMVEFDAERWQSQKNKILVSEPNHYMIYELAKLIQLLLGNNHYAA
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEE
FQNRPSDESNRSRLNKLMPLILSRIADLLAQIESGVKELQVQPQTKQKVISAVSRYIKQT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
NRYPLTITELCKITHVSRRALHYCFEQGLGVSPIQYIRDCRLNEIRRILLRDETEVIISD
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHH
LALDFGFFHISTFNAHYKQLFEETPTQTIQRSANYKNAIISYPKAGTDARS
HHHHHHHHEEEHHHHHHHHHHHHCHHHHHHHHCCCCHHHEECCCCCCCCCC
>Mature Secondary Structure
MHFVQQHHDRYAIALERCKSFTFDVNQQAESLIKWEQRYNQHSSGRFSGYLDELKLGGIH
CCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHH
LFEEFTNQTLLQQCCVKENSLWIGFSLQAQRPKINNNKIAAGQLMMRPSGVDFELMTPQD
HHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCEEECEEEECCCCCCEEEECCCC
FHIFGLVLDGKSLQDEMVEFDAERWQSQKNKILVSEPNHYMIYELAKLIQLLLGNNHYAA
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEE
FQNRPSDESNRSRLNKLMPLILSRIADLLAQIESGVKELQVQPQTKQKVISAVSRYIKQT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
NRYPLTITELCKITHVSRRALHYCFEQGLGVSPIQYIRDCRLNEIRRILLRDETEVIISD
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHH
LALDFGFFHISTFNAHYKQLFEETPTQTIQRSANYKNAIISYPKAGTDARS
HHHHHHHHEEEHHHHHHHHHHHHCHHHHHHHHCCCCHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8300522; 9205837; 9278503 [H]