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The map label for this gene is argC [H]

Identifier: 119944014

GI number: 119944014

Start: 289475

End: 290497

Strand: Direct

Name: argC [H]

Synonym: Ping_0228

Alternate gene names: 119944014

Gene position: 289475-290497 (Clockwise)

Preceding gene: 119944008

Following gene: 119944015

Centisome position: 6.35

GC content: 43.89

Gene sequence:

>1023_bases
ATGGAACTTCTTATGTTAAAAGCCATTATAGTGGGCGCAAGTGGTTATACGGGCGCCGAATTAGCAAATTTTTTAGTACG
TCATCCGCATATTGAATTGGCTGGTTTGTATGTGTCGCCGGGCAGTCTTGATAAAGGCAAAAAGTTATCTGCACTTTACG
GGCATTTATTAGGTGTGGTGGATTTACCTCTGCAGCCTTTGGGCAATGCTGATATTAAAACAGTATGTGCTGATATAGAT
ATCGTTATTTTGGCAACGGCGCATGAAGTAAGTCATGATTTAGTGCCGCTTTTTCTTGCTCAAAATACTGCGGTCTTTGA
TCTCTCTGGTGCATTTCGTGTTCAAGAAGCCGGTTTTTACGATAAATTTTATGGCTTTACGCACCAGTATCCTGCGTTAT
TAGAAAAAGCCGTTTACGGTTTAGCTGAATGGAATTTTGAAGCCGTTAAGAAAACCGATTTAATCGCGGTACCGGGCTGT
TACACCACCGCCTCTTTAACAGCATTAAAACCTCTGGTCGAAGCGGGATTAATTAAAGATAATACAAAACCCACTATTAA
TGCCACTAGTGGTGCCAGTGGCACTGGGCGTAAAGCGAGCCTCGCCAGTAGTTTTTGTGAGGTGAGTTTGCAGCCTTATG
GGGTTTTTACCCACCGTCATAAACCTGAAATTGATCAGCATTTGGGGATGCCGGTGGTATTTACACCGCATTTAGGCAGC
TTTAAACGCGGTATATTAGCCAGTATTAATGTGCAGCTAAAAGCGGGTGTGACCGCGCAGCAGGTTAATCAGGCTTACCA
GAATGCCTATGCGGATAAGCCCCTTGTGCGTTTGATGGACGGGACTTATCCTGCCCTTAAAAACGTGGTGGGTACTCCTT
TCTGTGATTTAGGTTGGGCTGTGGACGGGGAAGATCTGGTCGCTTTCAGTGCTATCGATAACCTTCTAAAAGGTGCTTCA
TCGCAGGCAATACAATGTATTAATTTACGTTTTGGTTTTGCTATCACCACTTCCCTTTTGTAA

Upstream 100 bases:

>100_bases
TCATTATTATTGCATAAATAATCAAATGTAATTAAAATGTCTTTCTCTCGGGAATATTTCTATTTATACTATTTTCCCTT
TTTTTAATACCGCAAATGAA

Downstream 100 bases:

>100_bases
GCAGGATTTTTAAACATGACTCAAGCATTAAAACCTTTATTAATTAAGCTTGGTGGTGCAGTACTTGAAAATGAGCAGGC
ATTAGAAAATTTATTTTCAG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MELLMLKAIIVGASGYTGAELANFLVRHPHIELAGLYVSPGSLDKGKKLSALYGHLLGVVDLPLQPLGNADIKTVCADID
IVILATAHEVSHDLVPLFLAQNTAVFDLSGAFRVQEAGFYDKFYGFTHQYPALLEKAVYGLAEWNFEAVKKTDLIAVPGC
YTTASLTALKPLVEAGLIKDNTKPTINATSGASGTGRKASLASSFCEVSLQPYGVFTHRHKPEIDQHLGMPVVFTPHLGS
FKRGILASINVQLKAGVTAQQVNQAYQNAYADKPLVRLMDGTYPALKNVVGTPFCDLGWAVDGEDLVAFSAIDNLLKGAS
SQAIQCINLRFGFAITTSLL

Sequences:

>Translated_340_residues
MELLMLKAIIVGASGYTGAELANFLVRHPHIELAGLYVSPGSLDKGKKLSALYGHLLGVVDLPLQPLGNADIKTVCADID
IVILATAHEVSHDLVPLFLAQNTAVFDLSGAFRVQEAGFYDKFYGFTHQYPALLEKAVYGLAEWNFEAVKKTDLIAVPGC
YTTASLTALKPLVEAGLIKDNTKPTINATSGASGTGRKASLASSFCEVSLQPYGVFTHRHKPEIDQHLGMPVVFTPHLGS
FKRGILASINVQLKAGVTAQQVNQAYQNAYADKPLVRLMDGTYPALKNVVGTPFCDLGWAVDGEDLVAFSAIDNLLKGAS
SQAIQCINLRFGFAITTSLL
>Mature_340_residues
MELLMLKAIIVGASGYTGAELANFLVRHPHIELAGLYVSPGSLDKGKKLSALYGHLLGVVDLPLQPLGNADIKTVCADID
IVILATAHEVSHDLVPLFLAQNTAVFDLSGAFRVQEAGFYDKFYGFTHQYPALLEKAVYGLAEWNFEAVKKTDLIAVPGC
YTTASLTALKPLVEAGLIKDNTKPTINATSGASGTGRKASLASSFCEVSLQPYGVFTHRHKPEIDQHLGMPVVFTPHLGS
FKRGILASINVQLKAGVTAQQVNQAYQNAYADKPLVRLMDGTYPALKNVVGTPFCDLGWAVDGEDLVAFSAIDNLLKGAS
SQAIQCINLRFGFAITTSLL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=336, Percent_Identity=62.202380952381, Blast_Score=416, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6320913, Length=337, Percent_Identity=30.5637982195846, Blast_Score=122, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 36421; Mature: 36421

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLMLKAIIVGASGYTGAELANFLVRHPHIELAGLYVSPGSLDKGKKLSALYGHLLGVV
CCHHEEEEHHCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
DLPLQPLGNADIKTVCADIDIVILATAHEVSHDLVPLFLAQNTAVFDLSGAFRVQEAGFY
CCCCCCCCCCCHHHHHCCCCEEEEEECHHHCCCCEEEEEECCCEEEECCCCEEEECCCCH
DKFYGFTHQYPALLEKAVYGLAEWNFEAVKKTDLIAVPGCYTTASLTALKPLVEAGLIKD
HHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCC
NTKPTINATSGASGTGRKASLASSFCEVSLQPYGVFTHRHKPEIDQHLGMPVVFTPHLGS
CCCCEEEECCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCHHHHCCCCEEECCCCCC
FKRGILASINVQLKAGVTAQQVNQAYQNAYADKPLVRLMDGTYPALKNVVGTPFCDLGWA
HHCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCE
VDGEDLVAFSAIDNLLKGASSQAIQCINLRFGFAITTSLL
ECCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEHHHCC
>Mature Secondary Structure
MELLMLKAIIVGASGYTGAELANFLVRHPHIELAGLYVSPGSLDKGKKLSALYGHLLGVV
CCHHEEEEHHCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
DLPLQPLGNADIKTVCADIDIVILATAHEVSHDLVPLFLAQNTAVFDLSGAFRVQEAGFY
CCCCCCCCCCCHHHHHCCCCEEEEEECHHHCCCCEEEEEECCCEEEECCCCEEEECCCCH
DKFYGFTHQYPALLEKAVYGLAEWNFEAVKKTDLIAVPGCYTTASLTALKPLVEAGLIKD
HHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCC
NTKPTINATSGASGTGRKASLASSFCEVSLQPYGVFTHRHKPEIDQHLGMPVVFTPHLGS
CCCCEEEECCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCHHHHCCCCEEECCCCCC
FKRGILASINVQLKAGVTAQQVNQAYQNAYADKPLVRLMDGTYPALKNVVGTPFCDLGWA
HHCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCE
VDGEDLVAFSAIDNLLKGASSQAIQCINLRFGFAITTSLL
ECCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10692366 [H]