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The map label for this gene is cobO [H]

Identifier: 119943999

GI number: 119943999

Start: 267138

End: 267734

Strand: Reverse

Name: cobO [H]

Synonym: Ping_0213

Alternate gene names: 119943999

Gene position: 267734-267138 (Counterclockwise)

Preceding gene: 119944000

Following gene: 119943996

Centisome position: 5.87

GC content: 42.21

Gene sequence:

>597_bases
ATGACCACAGATCCAAAACACTTAAAAAGAATGAAAGCCATTAAAGAAAAACAAGATCAAAAAATCGCAGCTGCGGATCA
AGAGCGCGGTGTCACCATTTTACTGGCAGGACCCGGTAAAGGTAAAAGCAGCTCCTCTTTTGGTATGTTAGCGCGTTCCT
TAGGTCACGGTCATAAAGTGGCAGTGGTACAGTTTTTAAAGGGTGCGATGTCGACCGGGGAAGAGATGTTTTTTAGCCAG
CAAGATAATGTTGATTGGTATGCTATGGGTGATGGTTTTACCTGGGAGACTCAAAATAAAGAACAGGATATTGCTAGTGC
AAAAAGAGCCTGGGCTAAAGCTGAAGCCTTATTGGCCGATGATAGATACCAATTGGTTATTCTTGATGAAATCACCTATA
TGTTCAAATTTAACTATTTAGAACTCCAGCCAACGCTGGATGCACTGAAAAATCGTCCCGAAAAAATGAATGTTATTTTA
ACCGGTCGAGGCCCCAAACAGGAGTTAATCGATGCGGTGGATACCTATAGCCATATTTTAGATGAAAAACATGCTTTTAA
AGCGGGCGTAAAAGCGCAGCCCGGGATTGAATGGTAG

Upstream 100 bases:

>100_bases
GCCCCGGTTATCAAAAAAGACAATAAATTAAATAGTTAGAGATTATCTAATGAGTCAAAACCTGCTATTTTTGCAGGCTT
TTTTACAACAGGAATTATTT

Downstream 100 bases:

>100_bases
AAAAAAGGCTGGAAAGCTGAAAGCCGAAAGCTAAAAGCGGGTTGTTAACCTTCCCGCCTTATAGCCTTATAACCTTATAA
CCTTATAGCCTTATAGCCTT

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTTDPKHLKRMKAIKEKQDQKIAAADQERGVTILLAGPGKGKSSSSFGMLARSLGHGHKVAVVQFLKGAMSTGEEMFFSQ
QDNVDWYAMGDGFTWETQNKEQDIASAKRAWAKAEALLADDRYQLVILDEITYMFKFNYLELQPTLDALKNRPEKMNVIL
TGRGPKQELIDAVDTYSHILDEKHAFKAGVKAQPGIEW

Sequences:

>Translated_198_residues
MTTDPKHLKRMKAIKEKQDQKIAAADQERGVTILLAGPGKGKSSSSFGMLARSLGHGHKVAVVQFLKGAMSTGEEMFFSQ
QDNVDWYAMGDGFTWETQNKEQDIASAKRAWAKAEALLADDRYQLVILDEITYMFKFNYLELQPTLDALKNRPEKMNVIL
TGRGPKQELIDAVDTYSHILDEKHAFKAGVKAQPGIEW
>Mature_197_residues
TTDPKHLKRMKAIKEKQDQKIAAADQERGVTILLAGPGKGKSSSSFGMLARSLGHGHKVAVVQFLKGAMSTGEEMFFSQQ
DNVDWYAMGDGFTWETQNKEQDIASAKRAWAKAEALLADDRYQLVILDEITYMFKFNYLELQPTLDALKNRPEKMNVILT
GRGPKQELIDAVDTYSHILDEKHAFKAGVKAQPGIEW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=43.3673469387755, Blast_Score=184, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22220; Mature: 22088

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDPKHLKRMKAIKEKQDQKIAAADQERGVTILLAGPGKGKSSSSFGMLARSLGHGHKV
CCCCHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHH
AVVQFLKGAMSTGEEMFFSQQDNVDWYAMGDGFTWETQNKEQDIASAKRAWAKAEALLAD
HHHHHHHHHHCCCHHHHHCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHCCC
DRYQLVILDEITYMFKFNYLELQPTLDALKNRPEKMNVILTGRGPKQELIDAVDTYSHIL
CCEEEEEEEEEEEHHEECEEEECCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
DEKHAFKAGVKAQPGIEW
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTDPKHLKRMKAIKEKQDQKIAAADQERGVTILLAGPGKGKSSSSFGMLARSLGHGHKV
CCCHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHH
AVVQFLKGAMSTGEEMFFSQQDNVDWYAMGDGFTWETQNKEQDIASAKRAWAKAEALLAD
HHHHHHHHHHCCCHHHHHCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHCCC
DRYQLVILDEITYMFKFNYLELQPTLDALKNRPEKMNVILTGRGPKQELIDAVDTYSHIL
CCEEEEEEEEEEEHHEECEEEECCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
DEKHAFKAGVKAQPGIEW
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]