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The map label for this gene is alr [H]

Identifier: 119943978

GI number: 119943978

Start: 241782

End: 242858

Strand: Reverse

Name: alr [H]

Synonym: Ping_0191

Alternate gene names: 119943978

Gene position: 242858-241782 (Counterclockwise)

Preceding gene: 119943979

Following gene: 119943977

Centisome position: 5.33

GC content: 44.57

Gene sequence:

>1077_bases
ATGGATACCATACGCGCAGTTATTAACTTAAAGGCATTACAGCACAATTTTCAGGTATTACAGAAAACGGCCCCACAGAG
CCAAATTATTGCAGTGATTAAAGCCAATGCTTATGGTCACGGCATGGTAAAAGTAGCCCAAAAATTACAACATGTGCACG
CTTTTGCCGTGGCTCGGTTAAGTGAGGCATTAATACTGCGTAGCGCGGGTATTAAGCACCCAATTATTTTATTAGGAGGC
TTTTTTAAGGACGGTGATCTGGCTACATTAAGTGCAGCAGATTTACAGTGCGTGGTGCACTCGCAGGAGCAAGTTGCTGC
GATTATGCAGGCCAAATTACCTAATCCCCTGAAAATTTGGTTAAAACTGGATACGGGTATGCACCGCTTAGGTTTTCATC
CGGAGCAGTTTGATGCCGTTTATAAACGCTTGGAGGGCTCGATAAATGTTCAAAAACCGATTAATTTTCTCACCCATTTC
CATTCTGCTGAAGAGGTGAATAACAATGCCACGGCGCAACAACTGTCTTTATTTAAGCAGTATATTCAAGCAGGCAGCGG
CTTAAAATCACTGGCTAATTCAGCGGCTGTTTTTGCCTGGCCCGAGACGCATTTTGATGCTGTCCGTCCGGGAATAGCCC
TCTATGGTATTTCACCTTTTGCCGATAGATTAGCAAAGGATTTACAATTACGTCCGGTGATGACCTTAAAATCAAGTTTG
ATTGCAATACGTGACCATAAAGCGAGAGAAAGTGTCGGTTACGGTGCTCATTGGACAGCCCAAAATGATACTCAACTTGG
GGTGGTAGCGATGGGTTATGGTGATGGTTATCCGCGTTTAGCACCAGAGGGTACACCTGTACTGGTCAATGGACGAATAG
TTCCGATTGTCGGTCGTATCTCAATGGATATGCTGACGATTGATTTAGGCTTAATGAATCAAGATAAAGTGGGTGATGAT
GTGACTCTCTGGGGCGAGGGATTACCCGCAGAAATTGTCGCACAAAAGATAGGCACTATCGCTTATGAACTGGTGACCAA
GTTAACCTCTCGTGTCACCCTGCATTACCAAGAGTGA

Upstream 100 bases:

>100_bases
ATGAATATACCGGTACAGCTTACCATGGGGAAGATTGATCATTTCTCAGGTGCCCGTTAAGCAATTACTTAAACCAATTT
ATAATAAATAGAGTTTAATT

Downstream 100 bases:

>100_bases
TTAACAGGCCGCAGATGCAACAAGGGATTAATAAACCCATATTTCAACAGGCTAAACTATTTCGCTATCAACTTCCCTTT
AAAATACCGATTGTCTTTAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MDTIRAVINLKALQHNFQVLQKTAPQSQIIAVIKANAYGHGMVKVAQKLQHVHAFAVARLSEALILRSAGIKHPIILLGG
FFKDGDLATLSAADLQCVVHSQEQVAAIMQAKLPNPLKIWLKLDTGMHRLGFHPEQFDAVYKRLEGSINVQKPINFLTHF
HSAEEVNNNATAQQLSLFKQYIQAGSGLKSLANSAAVFAWPETHFDAVRPGIALYGISPFADRLAKDLQLRPVMTLKSSL
IAIRDHKARESVGYGAHWTAQNDTQLGVVAMGYGDGYPRLAPEGTPVLVNGRIVPIVGRISMDMLTIDLGLMNQDKVGDD
VTLWGEGLPAEIVAQKIGTIAYELVTKLTSRVTLHYQE

Sequences:

>Translated_358_residues
MDTIRAVINLKALQHNFQVLQKTAPQSQIIAVIKANAYGHGMVKVAQKLQHVHAFAVARLSEALILRSAGIKHPIILLGG
FFKDGDLATLSAADLQCVVHSQEQVAAIMQAKLPNPLKIWLKLDTGMHRLGFHPEQFDAVYKRLEGSINVQKPINFLTHF
HSAEEVNNNATAQQLSLFKQYIQAGSGLKSLANSAAVFAWPETHFDAVRPGIALYGISPFADRLAKDLQLRPVMTLKSSL
IAIRDHKARESVGYGAHWTAQNDTQLGVVAMGYGDGYPRLAPEGTPVLVNGRIVPIVGRISMDMLTIDLGLMNQDKVGDD
VTLWGEGLPAEIVAQKIGTIAYELVTKLTSRVTLHYQE
>Mature_358_residues
MDTIRAVINLKALQHNFQVLQKTAPQSQIIAVIKANAYGHGMVKVAQKLQHVHAFAVARLSEALILRSAGIKHPIILLGG
FFKDGDLATLSAADLQCVVHSQEQVAAIMQAKLPNPLKIWLKLDTGMHRLGFHPEQFDAVYKRLEGSINVQKPINFLTHF
HSAEEVNNNATAQQLSLFKQYIQAGSGLKSLANSAAVFAWPETHFDAVRPGIALYGISPFADRLAKDLQLRPVMTLKSSL
IAIRDHKARESVGYGAHWTAQNDTQLGVVAMGYGDGYPRLAPEGTPVLVNGRIVPIVGRISMDMLTIDLGLMNQDKVGDD
VTLWGEGLPAEIVAQKIGTIAYELVTKLTSRVTLHYQE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=357, Percent_Identity=54.6218487394958, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1787439, Length=350, Percent_Identity=42, Blast_Score=274, Evalue=8e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39188; Mature: 39188

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIRAVINLKALQHNFQVLQKTAPQSQIIAVIKANAYGHGMVKVAQKLQHVHAFAVARL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
SEALILRSAGIKHPIILLGGFFKDGDLATLSAADLQCVVHSQEQVAAIMQAKLPNPLKIW
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHCCCCCEEEE
LKLDTGMHRLGFHPEQFDAVYKRLEGSINVQKPINFLTHFHSAEEVNNNATAQQLSLFKQ
EEECCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHH
YIQAGSGLKSLANSAAVFAWPETHFDAVRPGIALYGISPFADRLAKDLQLRPVMTLKSSL
HHHHCCCHHHHHCCCEEEECCCCHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHH
IAIRDHKARESVGYGAHWTAQNDTQLGVVAMGYGDGYPRLAPEGTPVLVNGRIVPIVGRI
HHHHCCHHHHCCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEEEEECCC
SMDMLTIDLGLMNQDKVGDDVTLWGEGLPAEIVAQKIGTIAYELVTKLTSRVTLHYQE
EEEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECC
>Mature Secondary Structure
MDTIRAVINLKALQHNFQVLQKTAPQSQIIAVIKANAYGHGMVKVAQKLQHVHAFAVARL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
SEALILRSAGIKHPIILLGGFFKDGDLATLSAADLQCVVHSQEQVAAIMQAKLPNPLKIW
HHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHCCCCCEEEE
LKLDTGMHRLGFHPEQFDAVYKRLEGSINVQKPINFLTHFHSAEEVNNNATAQQLSLFKQ
EEECCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHH
YIQAGSGLKSLANSAAVFAWPETHFDAVRPGIALYGISPFADRLAKDLQLRPVMTLKSSL
HHHHCCCHHHHHCCCEEEECCCCHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHH
IAIRDHKARESVGYGAHWTAQNDTQLGVVAMGYGDGYPRLAPEGTPVLVNGRIVPIVGRI
HHHHCCHHHHCCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEEEEECCC
SMDMLTIDLGLMNQDKVGDDVTLWGEGLPAEIVAQKIGTIAYELVTKLTSRVTLHYQE
EEEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA