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The map label for this gene is menC [H]

Identifier: 119943977

GI number: 119943977

Start: 240754

End: 241767

Strand: Reverse

Name: menC [H]

Synonym: Ping_0190

Alternate gene names: 119943977

Gene position: 241767-240754 (Counterclockwise)

Preceding gene: 119943978

Following gene: 119943976

Centisome position: 5.3

GC content: 39.35

Gene sequence:

>1014_bases
ATGCAACAAGGGATTAATAAACCCATATTTCAACAGGCTAAACTATTTCGCTATCAACTTCCCTTTAAAATACCGATTGT
CTTTAAAGGGATTAAGCTCACCGCTCGCGAGGGAGTGATCCTGCAGGTACAAAATGATAAGGGTGAGTTTAATTTTGCTG
AAATCGCACCTTTACCCGGTTTTAGCAAGGAGACTCTGCAACAGGCGACAGCACAAATAATAGCGCTGCTAAACACCCCT
CCGTTAAACAGCCAAAGCGATATCCTGTTATACCCCAGTGTGGCATTTGCACTTGACTGTATTTTACACAACATACCCAT
CTCAGAATTATTTAAAACAGCGGAAAGCATCCCGCTATTGCAGGGTGATAACCACAGTGTGCTTAAACAGTATCTGCAAT
TAAATAAGCCCAATAGCGTCAAATTAAAAATAGGCAGGCAATCCGTTGCGAAGGATATAACCCTATTTTCAGCATTAAGT
GCCCTCAATAATAATTTATTGATACGTTGTGATGCAAATCAGAGCTGGACTTTTGCGCAAGCAGATCTGTTTTTTGCCAA
TATTAATACTCAATTGATTGATTATATTGAGGAGCCAACAGCAAGCTTAAGCGATAATATCAACCTGGCTGAGCGTTACG
AGGTGCAGCTTGCTTTGGATGAAACCCTACAGCAAAAGCAGTTCCAGTATCAGCACCATCGATGTTTCAAGGCTCTGATT
TTAAAACCGACACTGATCGGCTCCTTTGAGCGCCTAAATTATTTTATAAAAACAGCCAAAAAATTTCATCTAAGTGTCAG
TATCAGCTCCTCATTTGAATCGCCGCTGGGTTTAAGTCAATTAGCTTTTCTTGCCAGCCAATGGTCAAAAGAGGTCGATA
TTTCCTGCGGATTGGATACGCTAAAATTTTTTGAAAGTGCCATCTTAAATAAAAATTCAGATAAAAAGTTAGATAATAAA
ACACCTATTAATCAACAAGTTAAACATTTGGAGTGTCTATGGACAAGCAACTGA

Upstream 100 bases:

>100_bases
AAATTGTCGCACAAAAGATAGGCACTATCGCTTATGAACTGGTGACCAAGTTAACCTCTCGTGTCACCCTGCATTACCAA
GAGTGATTAACAGGCCGCAG

Downstream 100 bases:

>100_bases
GTTTTTGCCCTGTCCGTCATCAGGCGATTATCAATGCGAATGCGCTAGCCATCGAGTCTGACGGGGTCTCGCTCACCTAC
CAGCAGTTAGACAATAGACT

Product: O-succinylbenzoate-CoA synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQQGINKPIFQQAKLFRYQLPFKIPIVFKGIKLTAREGVILQVQNDKGEFNFAEIAPLPGFSKETLQQATAQIIALLNTP
PLNSQSDILLYPSVAFALDCILHNIPISELFKTAESIPLLQGDNHSVLKQYLQLNKPNSVKLKIGRQSVAKDITLFSALS
ALNNNLLIRCDANQSWTFAQADLFFANINTQLIDYIEEPTASLSDNINLAERYEVQLALDETLQQKQFQYQHHRCFKALI
LKPTLIGSFERLNYFIKTAKKFHLSVSISSSFESPLGLSQLAFLASQWSKEVDISCGLDTLKFFESAILNKNSDKKLDNK
TPINQQVKHLECLWTSN

Sequences:

>Translated_337_residues
MQQGINKPIFQQAKLFRYQLPFKIPIVFKGIKLTAREGVILQVQNDKGEFNFAEIAPLPGFSKETLQQATAQIIALLNTP
PLNSQSDILLYPSVAFALDCILHNIPISELFKTAESIPLLQGDNHSVLKQYLQLNKPNSVKLKIGRQSVAKDITLFSALS
ALNNNLLIRCDANQSWTFAQADLFFANINTQLIDYIEEPTASLSDNINLAERYEVQLALDETLQQKQFQYQHHRCFKALI
LKPTLIGSFERLNYFIKTAKKFHLSVSISSSFESPLGLSQLAFLASQWSKEVDISCGLDTLKFFESAILNKNSDKKLDNK
TPINQQVKHLECLWTSN
>Mature_337_residues
MQQGINKPIFQQAKLFRYQLPFKIPIVFKGIKLTAREGVILQVQNDKGEFNFAEIAPLPGFSKETLQQATAQIIALLNTP
PLNSQSDILLYPSVAFALDCILHNIPISELFKTAESIPLLQGDNHSVLKQYLQLNKPNSVKLKIGRQSVAKDITLFSALS
ALNNNLLIRCDANQSWTFAQADLFFANINTQLIDYIEEPTASLSDNINLAERYEVQLALDETLQQKQFQYQHHRCFKALI
LKPTLIGSFERLNYFIKTAKKFHLSVSISSSFESPLGLSQLAFLASQWSKEVDISCGLDTLKFFESAILNKNSDKKLDNK
TPINQQVKHLECLWTSN

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=304, Percent_Identity=29.6052631578947, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 38078; Mature: 38078

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQGINKPIFQQAKLFRYQLPFKIPIVFKGIKLTAREGVILQVQNDKGEFNFAEIAPLPG
CCCCCCCHHHHHHHHHHEECCEEEEEEEECEEEEECCCEEEEEECCCCCCCCEEECCCCC
FSKETLQQATAQIIALLNTPPLNSQSDILLYPSVAFALDCILHNIPISELFKTAESIPLL
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHCCCE
QGDNHSVLKQYLQLNKPNSVKLKIGRQSVAKDITLFSALSALNNNLLIRCDANQSWTFAQ
ECCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEE
ADLFFANINTQLIDYIEEPTASLSDNINLAERYEVQLALDETLQQKQFQYQHHRCFKALI
EEEEEEECCHHHHHHHHCCCHHHCCCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LKPTLIGSFERLNYFIKTAKKFHLSVSISSSFESPLGLSQLAFLASQWSKEVDISCGLDT
HCCHHHCCHHHHHHHHHHCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCHHH
LKFFESAILNKNSDKKLDNKTPINQQVKHLECLWTSN
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHEEEEECCC
>Mature Secondary Structure
MQQGINKPIFQQAKLFRYQLPFKIPIVFKGIKLTAREGVILQVQNDKGEFNFAEIAPLPG
CCCCCCCHHHHHHHHHHEECCEEEEEEEECEEEEECCCEEEEEECCCCCCCCEEECCCCC
FSKETLQQATAQIIALLNTPPLNSQSDILLYPSVAFALDCILHNIPISELFKTAESIPLL
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHCCCE
QGDNHSVLKQYLQLNKPNSVKLKIGRQSVAKDITLFSALSALNNNLLIRCDANQSWTFAQ
ECCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEE
ADLFFANINTQLIDYIEEPTASLSDNINLAERYEVQLALDETLQQKQFQYQHHRCFKALI
EEEEEEECCHHHHHHHHCCCHHHCCCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LKPTLIGSFERLNYFIKTAKKFHLSVSISSSFESPLGLSQLAFLASQWSKEVDISCGLDT
HCCHHHCCHHHHHHHHHHCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCHHH
LKFFESAILNKNSDKKLDNKTPINQQVKHLECLWTSN
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA