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The map label for this gene is uxuR [H]

Identifier: 119943928

GI number: 119943928

Start: 180220

End: 181026

Strand: Direct

Name: uxuR [H]

Synonym: Ping_0138

Alternate gene names: 119943928

Gene position: 180220-181026 (Clockwise)

Preceding gene: 119943927

Following gene: 119943929

Centisome position: 3.95

GC content: 41.76

Gene sequence:

>807_bases
ATGATAGTTGTCGGGTATGCCAATAGATGGAAGATTATTATGAATGCAGTTGTAACACCTCAAAAACGTCTTTACCAAAA
GATTGGTCAAGGTTTAAAAGATCGCATCGTTAGTGGAGAATTCGTTGTCGGTGATCGCCTTCCTCCAGAAAGAGAAATTG
CTGTGCAATGCCAAGTGAGTCGTTCAGTAGTACGGGAAGCTTTGATCATGCTGGAATTACAAGATGTAGTGGAAGTAAGG
AAGGGCTCGGGTGTTTATATTATTAATCAACCAAAGGAAGATATTGATGCAAAAACCGGTACCAGTGAATCTGATGATGC
AGGTCCCTTTGAAATGTTACAGGCGCGACAATTACTAGAAAGCCATATAGCAGAATTCGCGGCAACTCAAGTCACGAGAA
ATGATATTTTTCGTTTGCGTAAAGCGTTACAAATGGAGCGCCAGCAAATTGAAGGTGCAAGCTTCGATTATGATGGCGAT
AAAATGTTTCATATGGCGATTGCCGAAGCTACCCAAAATAAGGTGCTGGTAGATATGGTTGAAGATTTATGGGTACGTCG
TCAAAACAGCTCGATGTGGCTCCAATTACATGCGCGTATTGTCAATCAAAATTACCGCAAAGCCTGGCTGGAAGATCATG
AAAAAATATTGCTGGCTTTACAGCACCGAGACGCCAGTGCTGCAAGAGATGCGATGTGGCAACATCTTGAAAATGTTAAG
CAAACATTACTGGAACTATCTGATGTGGATGACCCTCTATTTGATGGTTTTTTATTCAGCAATAATCCAGTGGTCTCGTT
GGCTTAG

Upstream 100 bases:

>100_bases
ACAATGGTTAACTAGCGCATAGCCATTAAAAAATCCTGGCGGGTATTTTTTAGTCTTTTTATTGGTTGACCAAAGTATTG
ATCTGCTATCGATAAATGTT

Downstream 100 bases:

>100_bases
CCCTCGCTAACAGAAACGATTGAACCTGATAAAGACAGATGATACTAAATTAACTGCTACTCATTGAGAAGTTATCTGGT
ATGTTGAGGAACACTTATTC

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MIVVGYANRWKIIMNAVVTPQKRLYQKIGQGLKDRIVSGEFVVGDRLPPEREIAVQCQVSRSVVREALIMLELQDVVEVR
KGSGVYIINQPKEDIDAKTGTSESDDAGPFEMLQARQLLESHIAEFAATQVTRNDIFRLRKALQMERQQIEGASFDYDGD
KMFHMAIAEATQNKVLVDMVEDLWVRRQNSSMWLQLHARIVNQNYRKAWLEDHEKILLALQHRDASAARDAMWQHLENVK
QTLLELSDVDDPLFDGFLFSNNPVVSLA

Sequences:

>Translated_268_residues
MIVVGYANRWKIIMNAVVTPQKRLYQKIGQGLKDRIVSGEFVVGDRLPPEREIAVQCQVSRSVVREALIMLELQDVVEVR
KGSGVYIINQPKEDIDAKTGTSESDDAGPFEMLQARQLLESHIAEFAATQVTRNDIFRLRKALQMERQQIEGASFDYDGD
KMFHMAIAEATQNKVLVDMVEDLWVRRQNSSMWLQLHARIVNQNYRKAWLEDHEKILLALQHRDASAARDAMWQHLENVK
QTLLELSDVDDPLFDGFLFSNNPVVSLA
>Mature_268_residues
MIVVGYANRWKIIMNAVVTPQKRLYQKIGQGLKDRIVSGEFVVGDRLPPEREIAVQCQVSRSVVREALIMLELQDVVEVR
KGSGVYIINQPKEDIDAKTGTSESDDAGPFEMLQARQLLESHIAEFAATQVTRNDIFRLRKALQMERQQIEGASFDYDGD
KMFHMAIAEATQNKVLVDMVEDLWVRRQNSSMWLQLHARIVNQNYRKAWLEDHEKILLALQHRDASAARDAMWQHLENVK
QTLLELSDVDDPLFDGFLFSNNPVVSLA

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=249, Percent_Identity=51.004016064257, Blast_Score=258, Evalue=3e-70,
Organism=Escherichia coli, GI87082208, Length=252, Percent_Identity=48.4126984126984, Blast_Score=211, Evalue=3e-56,
Organism=Escherichia coli, GI1790032, Length=232, Percent_Identity=29.7413793103448, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786303, Length=243, Percent_Identity=27.9835390946502, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787821, Length=231, Percent_Identity=25.5411255411255, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789621, Length=229, Percent_Identity=27.0742358078603, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789353, Length=231, Percent_Identity=26.8398268398268, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 30692; Mature: 30692

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVGYANRWKIIMNAVVTPQKRLYQKIGQGLKDRIVSGEFVVGDRLPPEREIAVQCQVS
CEEEEECCHHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCCEEECCCCCCCCCEEEEHHHH
RSVVREALIMLELQDVVEVRKGSGVYIINQPKEDIDAKTGTSESDDAGPFEMLQARQLLE
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
SHIAEFAATQVTRNDIFRLRKALQMERQQIEGASFDYDGDKMFHMAIAEATQNKVLVDMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
EDLWVRRQNSSMWLQLHARIVNQNYRKAWLEDHEKILLALQHRDASAARDAMWQHLENVK
HHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QTLLELSDVDDPLFDGFLFSNNPVVSLA
HHHHHHHCCCCHHHCCEEECCCCEEEEC
>Mature Secondary Structure
MIVVGYANRWKIIMNAVVTPQKRLYQKIGQGLKDRIVSGEFVVGDRLPPEREIAVQCQVS
CEEEEECCHHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCCEEECCCCCCCCCEEEEHHHH
RSVVREALIMLELQDVVEVRKGSGVYIINQPKEDIDAKTGTSESDDAGPFEMLQARQLLE
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
SHIAEFAATQVTRNDIFRLRKALQMERQQIEGASFDYDGDKMFHMAIAEATQNKVLVDMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
EDLWVRRQNSSMWLQLHARIVNQNYRKAWLEDHEKILLALQHRDASAARDAMWQHLENVK
HHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QTLLELSDVDDPLFDGFLFSNNPVVSLA
HHHHHHHCCCCHHHCCEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]