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The map label for this gene is glmS [H]

Identifier: 119943878

GI number: 119943878

Start: 113145

End: 114980

Strand: Direct

Name: glmS [H]

Synonym: Ping_0085

Alternate gene names: 119943878

Gene position: 113145-114980 (Clockwise)

Preceding gene: 119943875

Following gene: 119943881

Centisome position: 2.48

GC content: 44.17

Gene sequence:

>1836_bases
ATGTGTGGAATCGTTGGTGCAGTAGCACAAAGAGATGTATCTGAAATCTTATTAGAAGGATTACAACGCTTAGAATATCG
CGGTTATGATTCAGCAGGCCTTGCCGTTATTAGTGCTGATGGACAATTACAACGAACACGTCGTTTAGGAAAAGTAAAAG
AATTAGCCAATGCGGTTGCCGCTAATCCTGTCAGCGGTGGAACCGGTATTGCACATACGCGCTGGGCAACACATGGAGAG
CCCTCAGAAGCCAATGCACATCCTCATCTCTCCGGCGATAATATTGTTATCGTCCATAACGGTATTATTGAAAACTACGA
AAGCTTACGCGAAACCCTGCGCGGGCGTGGTTATGAATTTCTTTCACAAACCGATACTGAAGTAATTTGCCATCTTGTTG
AATGGGAATTACGCAGTGCAGAAACACTTTTAGAAGCCGTGCAAAAGACATTGCCTCAGCTGGAAGGTGCCTATGGCACT
GTGGTCATGGATCGCCGTGATCCAAGTCGTTTAGTGGTCGCCCGTTCGGGGAGTCCACTGGTAATAGGCTTGGGAGTTGG
GGAAAATTTTCTGGCATCGGACCAACTGGCTTTATTAAATGTAACACGTCGTTTTATCTTCTTAGAAGAAGGGGATGTTG
CTGAAATTACCCGCCGAGACATTAATGTTTTTGATTTGAATGGCAAGGCGATTGAGCGTGAAGTTCACGAATCAACTATT
GAGCAAGATGCAGCCGATAAAGGCAAGTACAGACACTTTATGCAAAAAGAAATTTTCGAGCAACCCAGCGCATTAATAAA
TGCAATGGAAGGTCGAATCAGTCATGACAGTGTATTAGTTGAGAGTATTGGTGTTGGTGCAAAAGATATCCTGAAAAATG
TAGAGCATGTACAGATTATCGCCTGCGGTACATCTTATAACTCAGGCATGGCTGCCCGTTACTGGTTTGAGTCCCTCGCC
GGCGTAAGCTGTGATGTGGAAATAGCTTCTGAATTCCGTTACCGAGATTTTGTCGTGCGTCCAAATAGCCTATTGCTGAC
TCTGTCACAATCGGGTGAAACTGCAGATACGCTGGCAGCGTTACGCTTAGCCAAGCAGAAAGGTTACATGTCGGCGATGT
CTATCTGTAATGTTTCCGGGTCATCTTTGGTACGCGAATCGGATCTTGCTTTTATGACCCGCGCGGGTACTGAGATTGGT
GTTGCATCCACCAAAGCATTTACAACGCAGCTGGCTGCCATGCTTATTTTGGTTACCGCTATTGGTAAAGAGCAGGGCAC
TATCAGCAAAGAAAAAGAAGCAAAGATTGTACGTGCATTGCATTCACTCCCAGCGCAAATTGAGAAAGCATTAGCCTTTG
ATAAACCGATTGAAGCCTTAGCAGAAGATTTTGCAGATAAAGAGCACACATTATTCTTAGGCCGGGGTGAATTTTACCCT
ATTGCCATGGAAGCGGCGCTTAAATTGAAAGAAATTTCATACATTCATGCTGAAGCTTATGCGGCAGGTGAGTTGAAGCA
TGGCCCATTAGCGCTAGTTGATGCAGATATGCCCGTTGTTGTGGTTGCACCAACCAATGACTTGCTTGAAAAAGTTAAAT
CAAATATTGAAGAGGTACGTGCACGTGGTGGTCAGTTGTATGTATTTGCAGATGAAAGCGCCGGGTTTGAAAGTTCTGAA
GGTATGAAAATTATTACTTTACCCAGTGTAGATGAAATCATTGCTCCTATTTTTTACACTGTGCCAATGCAGTTATTGGC
TTATCATGTGGCATTAATTAAAGGCACTGATGTGGATCAACCGCGTAATCTTGCAAAAGCGGTTACGGTTGAATAA

Upstream 100 bases:

>100_bases
AATGCATGGAAATACGATATTATGCATGTTTTGCCGTGATCGTTTTTTAAATACGTATTAATTTATTTTTGTTTATCAAT
ATTGTTTGGAGTATAGCTAT

Downstream 100 bases:

>100_bases
TCATTAAGTTGAGTAATGCTTGTTTTGTCCTATGACGATCAAGTTTTAAATGTTGCATAAAAATTTAAAACCTGGTTAAA
CTGATTAACAGTTGACCGGT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MCGIVGAVAQRDVSEILLEGLQRLEYRGYDSAGLAVISADGQLQRTRRLGKVKELANAVAANPVSGGTGIAHTRWATHGE
PSEANAHPHLSGDNIVIVHNGIIENYESLRETLRGRGYEFLSQTDTEVICHLVEWELRSAETLLEAVQKTLPQLEGAYGT
VVMDRRDPSRLVVARSGSPLVIGLGVGENFLASDQLALLNVTRRFIFLEEGDVAEITRRDINVFDLNGKAIEREVHESTI
EQDAADKGKYRHFMQKEIFEQPSALINAMEGRISHDSVLVESIGVGAKDILKNVEHVQIIACGTSYNSGMAARYWFESLA
GVSCDVEIASEFRYRDFVVRPNSLLLTLSQSGETADTLAALRLAKQKGYMSAMSICNVSGSSLVRESDLAFMTRAGTEIG
VASTKAFTTQLAAMLILVTAIGKEQGTISKEKEAKIVRALHSLPAQIEKALAFDKPIEALAEDFADKEHTLFLGRGEFYP
IAMEAALKLKEISYIHAEAYAAGELKHGPLALVDADMPVVVVAPTNDLLEKVKSNIEEVRARGGQLYVFADESAGFESSE
GMKIITLPSVDEIIAPIFYTVPMQLLAYHVALIKGTDVDQPRNLAKAVTVE

Sequences:

>Translated_611_residues
MCGIVGAVAQRDVSEILLEGLQRLEYRGYDSAGLAVISADGQLQRTRRLGKVKELANAVAANPVSGGTGIAHTRWATHGE
PSEANAHPHLSGDNIVIVHNGIIENYESLRETLRGRGYEFLSQTDTEVICHLVEWELRSAETLLEAVQKTLPQLEGAYGT
VVMDRRDPSRLVVARSGSPLVIGLGVGENFLASDQLALLNVTRRFIFLEEGDVAEITRRDINVFDLNGKAIEREVHESTI
EQDAADKGKYRHFMQKEIFEQPSALINAMEGRISHDSVLVESIGVGAKDILKNVEHVQIIACGTSYNSGMAARYWFESLA
GVSCDVEIASEFRYRDFVVRPNSLLLTLSQSGETADTLAALRLAKQKGYMSAMSICNVSGSSLVRESDLAFMTRAGTEIG
VASTKAFTTQLAAMLILVTAIGKEQGTISKEKEAKIVRALHSLPAQIEKALAFDKPIEALAEDFADKEHTLFLGRGEFYP
IAMEAALKLKEISYIHAEAYAAGELKHGPLALVDADMPVVVVAPTNDLLEKVKSNIEEVRARGGQLYVFADESAGFESSE
GMKIITLPSVDEIIAPIFYTVPMQLLAYHVALIKGTDVDQPRNLAKAVTVE
>Mature_611_residues
MCGIVGAVAQRDVSEILLEGLQRLEYRGYDSAGLAVISADGQLQRTRRLGKVKELANAVAANPVSGGTGIAHTRWATHGE
PSEANAHPHLSGDNIVIVHNGIIENYESLRETLRGRGYEFLSQTDTEVICHLVEWELRSAETLLEAVQKTLPQLEGAYGT
VVMDRRDPSRLVVARSGSPLVIGLGVGENFLASDQLALLNVTRRFIFLEEGDVAEITRRDINVFDLNGKAIEREVHESTI
EQDAADKGKYRHFMQKEIFEQPSALINAMEGRISHDSVLVESIGVGAKDILKNVEHVQIIACGTSYNSGMAARYWFESLA
GVSCDVEIASEFRYRDFVVRPNSLLLTLSQSGETADTLAALRLAKQKGYMSAMSICNVSGSSLVRESDLAFMTRAGTEIG
VASTKAFTTQLAAMLILVTAIGKEQGTISKEKEAKIVRALHSLPAQIEKALAFDKPIEALAEDFADKEHTLFLGRGEFYP
IAMEAALKLKEISYIHAEAYAAGELKHGPLALVDADMPVVVVAPTNDLLEKVKSNIEEVRARGGQLYVFADESAGFESSE
GMKIITLPSVDEIIAPIFYTVPMQLLAYHVALIKGTDVDQPRNLAKAVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=689, Percent_Identity=36.7198838896952, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=36.9343065693431, Blast_Score=418, Evalue=1e-117,
Organism=Homo sapiens, GI29570798, Length=266, Percent_Identity=25.187969924812, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=71.3584288052373, Blast_Score=912, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=220, Percent_Identity=29.0909090909091, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17539970, Length=433, Percent_Identity=39.2609699769053, Blast_Score=289, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17532899, Length=433, Percent_Identity=38.1062355658199, Blast_Score=282, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17532897, Length=433, Percent_Identity=38.1062355658199, Blast_Score=282, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6322745, Length=463, Percent_Identity=36.9330453563715, Blast_Score=283, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6323731, Length=431, Percent_Identity=31.0904872389791, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=37.5609756097561, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323958, Length=164, Percent_Identity=26.219512195122, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357745, Length=687, Percent_Identity=36.098981077147, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI28573187, Length=266, Percent_Identity=25.187969924812, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24659598, Length=266, Percent_Identity=24.812030075188, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66582; Mature: 66582

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRDVSEILLEGLQRLEYRGYDSAGLAVISADGQLQRTRRLGKVKELANAVA
CCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
ANPVSGGTGIAHTRWATHGEPSEANAHPHLSGDNIVIVHNGIIENYESLRETLRGRGYEF
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCHH
LSQTDTEVICHLVEWELRSAETLLEAVQKTLPQLEGAYGTVVMDRRDPSRLVVARSGSPL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCE
VIGLGVGENFLASDQLALLNVTRRFIFLEEGDVAEITRRDINVFDLNGKAIEREVHESTI
EEEECCCCCCCCCCCHHHHHHHHHEEEEECCCHHHHHHCCCEEEECCCHHHHHHHHHHHH
EQDAADKGKYRHFMQKEIFEQPSALINAMEGRISHDSVLVESIGVGAKDILKNVEHVQII
HHHHHCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCEEEEE
ACGTSYNSGMAARYWFESLAGVSCDVEIASEFRYRDFVVRPNSLLLTLSQSGETADTLAA
EECCCCCCCCHHHHHHHHHCCCEEEEHHHHCCCCCEEEECCCEEEEEEECCCCHHHHHHH
LRLAKQKGYMSAMSICNVSGSSLVRESDLAFMTRAGTEIGVASTKAFTTQLAAMLILVTA
HHHHHHCCHHHHHHHHCCCCCHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
IGKEQGTISKEKEAKIVRALHSLPAQIEKALAFDKPIEALAEDFADKEHTLFLGRGEFYP
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCEEE
IAMEAALKLKEISYIHAEAYAAGELKHGPLALVDADMPVVVVAPTNDLLEKVKSNIEEVR
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHH
ARGGQLYVFADESAGFESSEGMKIITLPSVDEIIAPIFYTVPMQLLAYHVALIKGTDVDQ
HCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
PRNLAKAVTVE
CHHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRDVSEILLEGLQRLEYRGYDSAGLAVISADGQLQRTRRLGKVKELANAVA
CCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
ANPVSGGTGIAHTRWATHGEPSEANAHPHLSGDNIVIVHNGIIENYESLRETLRGRGYEF
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCHH
LSQTDTEVICHLVEWELRSAETLLEAVQKTLPQLEGAYGTVVMDRRDPSRLVVARSGSPL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCE
VIGLGVGENFLASDQLALLNVTRRFIFLEEGDVAEITRRDINVFDLNGKAIEREVHESTI
EEEECCCCCCCCCCCHHHHHHHHHEEEEECCCHHHHHHCCCEEEECCCHHHHHHHHHHHH
EQDAADKGKYRHFMQKEIFEQPSALINAMEGRISHDSVLVESIGVGAKDILKNVEHVQII
HHHHHCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCCEEEEE
ACGTSYNSGMAARYWFESLAGVSCDVEIASEFRYRDFVVRPNSLLLTLSQSGETADTLAA
EECCCCCCCCHHHHHHHHHCCCEEEEHHHHCCCCCEEEECCCEEEEEEECCCCHHHHHHH
LRLAKQKGYMSAMSICNVSGSSLVRESDLAFMTRAGTEIGVASTKAFTTQLAAMLILVTA
HHHHHHCCHHHHHHHHCCCCCHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
IGKEQGTISKEKEAKIVRALHSLPAQIEKALAFDKPIEALAEDFADKEHTLFLGRGEFYP
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCEEE
IAMEAALKLKEISYIHAEAYAAGELKHGPLALVDADMPVVVVAPTNDLLEKVKSNIEEVR
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHH
ARGGQLYVFADESAGFESSEGMKIITLPSVDEIIAPIFYTVPMQLLAYHVALIKGTDVDQ
HCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
PRNLAKAVTVE
CHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA