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The map label for this gene is trkH [H]

Identifier: 119943875

GI number: 119943875

Start: 109302

End: 110747

Strand: Direct

Name: trkH [H]

Synonym: Ping_0082

Alternate gene names: 119943875

Gene position: 109302-110747 (Clockwise)

Preceding gene: 119943874

Following gene: 119943878

Centisome position: 2.4

GC content: 40.8

Gene sequence:

>1446_bases
GTGGTTACTCGTCCCCTGCTCTTTATTACCGGATTGGTATTGTCAAAAATGGCAATATTTATGTATCCGCCCATGGTCTT
CGCTTTTTATAATAATACCTTAGGTGGCGTAGAATTTTTATCCTCTATTATTATTACTCACCTGGCTTCTGCTCTTTTTA
TTTTTATGGGCAAAGAAAAAGAATTCTCTCGCTTAGGTGTAAGAGAGATGTTTTTATTAACCACCGGGGTGTGGGTTTTA
GCCAGTATGTTTGCCGCATTACCTTTTGTGCTGATTGAACATATTAATTTTAGTAATGCTTTTTTTGAAACCATGTCGGG
TATTACTACAACGGGCAGTACAGTACTTAATAATTTAGATACTATGCATCCGAGTATTTTATTGTGGCGCTCCATTTTAC
AATGGTTAGGTGGCGTTGGTTTTATCGTGATGGGGGTGGCTATTTTACCCTTTTTGAATGTCGGCGGGATGCGCCTCTTC
CAGACAGAATCGTCAGACTGGTCAGATAAAGCTGAATCTAAAACGCGCAGTGTCGCAATCGATATTTTGTTGGTCTACAT
CTTCTTAAGCGTGTGCTGTTTTGTTGGCTATCGTCTTGCCGGTATGGGGAGTTTCGATGCAATAAATCATGCTATGACGA
CTATTTCGACGGGGGGATACTCAACTTCAGATCGTTCAATGGGAAATTTTTCCAATGCAGCACATTGGAATGCCATTATT
TTTATGTTTTTGGGTGGGTTGCCATTTTTATTATTGATACGTGCCTTTAACCAACACAGTTTAGTCACTCTTTTCCGTGA
TGCTCAAGTCTTAGGCTTTATTAAAGTGGTCTTGTTCTTTACTTTAAGCTTAACCGCTTATTTAGTGTTCAGTGATCAAT
TCTCCCCGGCTAATGCCTTGCGATTAAGTTTATTTAATGTCGTTTCTGTGGTCACAACCACAGGCTTTGGGCTTGATGAT
TTTATTTCCTGGGGAGATTTTAGTCTTGTTGTTTTTTGGGGGTTAATGTTTTCTGGTGCTTGTTCCGGTTCAACCTCGGG
TGGTATAAAAATATTCCGCTTTCAAATTGCCACCAGTATGCTTAAACGTCAGTTAATGATCTTAATTCACCCTCGTGGCA
TCTTTCCGCAACGTTACAATAATCGCACCGTAAGCGATGATATTCTACGCTCTTTAATTGCTTTTATTTTGGCCTATATG
GGCACTATTGCAGTCTCAACCTTATTATTAGCACTGTTTGGCTCAACGGCTATTGTTGCTCTGTCTGCCTCCATTACTGC
CGTTTCCAATGTTGGACCCGGCCTGGATCCGAGCATTGGTCCAAGCGGAAATTTTTCAGCTTTATCGGATCCTTCCAAAT
GGGTTTTAGCCATTGGTATGCTAATGGGACGATTAGAGATACTGACTGTGGTGGTCTTGTTTTTACCTCATTTTTGGCGC
CGTTAG

Upstream 100 bases:

>100_bases
CGATGACCACGTTATATTATTTCTGGTGAATAAAAAGTTTATCAGCGATATTGAAAAATTATTTCAACCTAGTCCGTTCT
TTTTGTAGCTCTGTCATCCT

Downstream 100 bases:

>100_bases
TACTGGCTTTTTTAGCCTTATACCGAACGCATTAATAAAGTGATCAGATTTACCATTCAAATTCATCCTGACGGCTTTGT
GAGCGTAAATTTACCTTTCA

Product: potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVTRPLLFITGLVLSKMAIFMYPPMVFAFYNNTLGGVEFLSSIIITHLASALFIFMGKEKEFSRLGVREMFLLTTGVWVL
ASMFAALPFVLIEHINFSNAFFETMSGITTTGSTVLNNLDTMHPSILLWRSILQWLGGVGFIVMGVAILPFLNVGGMRLF
QTESSDWSDKAESKTRSVAIDILLVYIFLSVCCFVGYRLAGMGSFDAINHAMTTISTGGYSTSDRSMGNFSNAAHWNAII
FMFLGGLPFLLLIRAFNQHSLVTLFRDAQVLGFIKVVLFFTLSLTAYLVFSDQFSPANALRLSLFNVVSVVTTTGFGLDD
FISWGDFSLVVFWGLMFSGACSGSTSGGIKIFRFQIATSMLKRQLMILIHPRGIFPQRYNNRTVSDDILRSLIAFILAYM
GTIAVSTLLLALFGSTAIVALSASITAVSNVGPGLDPSIGPSGNFSALSDPSKWVLAIGMLMGRLEILTVVVLFLPHFWR
R

Sequences:

>Translated_481_residues
MVTRPLLFITGLVLSKMAIFMYPPMVFAFYNNTLGGVEFLSSIIITHLASALFIFMGKEKEFSRLGVREMFLLTTGVWVL
ASMFAALPFVLIEHINFSNAFFETMSGITTTGSTVLNNLDTMHPSILLWRSILQWLGGVGFIVMGVAILPFLNVGGMRLF
QTESSDWSDKAESKTRSVAIDILLVYIFLSVCCFVGYRLAGMGSFDAINHAMTTISTGGYSTSDRSMGNFSNAAHWNAII
FMFLGGLPFLLLIRAFNQHSLVTLFRDAQVLGFIKVVLFFTLSLTAYLVFSDQFSPANALRLSLFNVVSVVTTTGFGLDD
FISWGDFSLVVFWGLMFSGACSGSTSGGIKIFRFQIATSMLKRQLMILIHPRGIFPQRYNNRTVSDDILRSLIAFILAYM
GTIAVSTLLLALFGSTAIVALSASITAVSNVGPGLDPSIGPSGNFSALSDPSKWVLAIGMLMGRLEILTVVVLFLPHFWR
R
>Mature_481_residues
MVTRPLLFITGLVLSKMAIFMYPPMVFAFYNNTLGGVEFLSSIIITHLASALFIFMGKEKEFSRLGVREMFLLTTGVWVL
ASMFAALPFVLIEHINFSNAFFETMSGITTTGSTVLNNLDTMHPSILLWRSILQWLGGVGFIVMGVAILPFLNVGGMRLF
QTESSDWSDKAESKTRSVAIDILLVYIFLSVCCFVGYRLAGMGSFDAINHAMTTISTGGYSTSDRSMGNFSNAAHWNAII
FMFLGGLPFLLLIRAFNQHSLVTLFRDAQVLGFIKVVLFFTLSLTAYLVFSDQFSPANALRLSLFNVVSVVTTTGFGLDD
FISWGDFSLVVFWGLMFSGACSGSTSGGIKIFRFQIATSMLKRQLMILIHPRGIFPQRYNNRTVSDDILRSLIAFILAYM
GTIAVSTLLLALFGSTAIVALSASITAVSNVGPGLDPSIGPSGNFSALSDPSKWVLAIGMLMGRLEILTVVVLFLPHFWR
R

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=430, Percent_Identity=36.2790697674419, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787626, Length=427, Percent_Identity=31.615925058548, Blast_Score=208, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52810; Mature: 52810

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTRPLLFITGLVLSKMAIFMYPPMVFAFYNNTLGGVEFLSSIIITHLASALFIFMGKEK
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EFSRLGVREMFLLTTGVWVLASMFAALPFVLIEHINFSNAFFETMSGITTTGSTVLNNLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHH
TMHPSILLWRSILQWLGGVGFIVMGVAILPFLNVGGMRLFQTESSDWSDKAESKTRSVAI
HHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHH
DILLVYIFLSVCCFVGYRLAGMGSFDAINHAMTTISTGGYSTSDRSMGNFSNAAHWNAII
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHH
FMFLGGLPFLLLIRAFNQHSLVTLFRDAQVLGFIKVVLFFTLSLTAYLVFSDQFSPANAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RLSLFNVVSVVTTTGFGLDDFISWGDFSLVVFWGLMFSGACSGSTSGGIKIFRFQIATSM
HHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHH
LKRQLMILIHPRGIFPQRYNNRTVSDDILRSLIAFILAYMGTIAVSTLLLALFGSTAIVA
HHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LSASITAVSNVGPGLDPSIGPSGNFSALSDPSKWVLAIGMLMGRLEILTVVVLFLPHFWR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
R
C
>Mature Secondary Structure
MVTRPLLFITGLVLSKMAIFMYPPMVFAFYNNTLGGVEFLSSIIITHLASALFIFMGKEK
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EFSRLGVREMFLLTTGVWVLASMFAALPFVLIEHINFSNAFFETMSGITTTGSTVLNNLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHH
TMHPSILLWRSILQWLGGVGFIVMGVAILPFLNVGGMRLFQTESSDWSDKAESKTRSVAI
HHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHH
DILLVYIFLSVCCFVGYRLAGMGSFDAINHAMTTISTGGYSTSDRSMGNFSNAAHWNAII
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHH
FMFLGGLPFLLLIRAFNQHSLVTLFRDAQVLGFIKVVLFFTLSLTAYLVFSDQFSPANAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RLSLFNVVSVVTTTGFGLDDFISWGDFSLVVFWGLMFSGACSGSTSGGIKIFRFQIATSM
HHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHH
LKRQLMILIHPRGIFPQRYNNRTVSDDILRSLIAFILAYMGTIAVSTLLLALFGSTAIVA
HHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LSASITAVSNVGPGLDPSIGPSGNFSALSDPSKWVLAIGMLMGRLEILTVVVLFLPHFWR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]