BacMap

Definition	Psychromonas ingrahamii 37, complete genome.
Accession	NC_008709
Length	4,559,598

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The map label for this gene is sdh [H]

Identifier: 119943838

GI number: 119943838

Start: 65289

End: 66059

Strand: Reverse

Name: sdh [H]

Synonym: Ping_0045

Alternate gene names: 119943838

Gene position: 66059-65289 (Counterclockwise)

Preceding gene: 119943839

Following gene: 119943834

Centisome position: 1.45

GC content: 40.47

Gene sequence:

>771_bases
ATGAACACAAAATTAATGCCCACCGTTTTAATCACCGGAGCAACATCTGGATTTGGGCTGGCAACCGCGAAAAAATTTGC
TCAACATGGTTATCCATTAATTATTACTGGCCGTAGAAAAGAACGATTGCAGAAGCTCAGCGATCAACTATCACCAATAA
CAGATGTCTTTTTTTATCAGTTAGATGTACGTGACAGTGAGGCTATAAAAACATTTACTCAGGCTATTCCTGATAATTTT
AAGCAGGTATCAATATTGGTCAATAATGCAGGTCTTGCTTTGGGCACAGAGTCTGCAGATAAGGCATCACTGGATGACTG
GCATACAATGATAGATACCAATGTCACGGGACTGGTCAATGTGACTCACAGTTTGTTACCTATATTACGTAAACAAGCAT
CGGCCAGTATTATTAACCTTGCGAGCATAGCAGCTAATTGGTCTTATCCGGGCAGCCATGTTTATGGTGCAAGCAAAGCA
TTTGTGGCACAATTTTCCAGAAATCTGCGCAGTGACTTTGCCGGGACCGGCGTACGCGTTACCAGTTTAGAACCGGGTTT
ATCTGAAAGTGAATTTAGCCTGGTAAGGTTTAAAGGGGATAAAGAAAAATACCAGCAAATTTATAACAATGCTGATGCCC
TACAACCTGAAGATATCGCTAATATTATATTCTGGATAGCAGAGCAGCCTGCTCACATTAATATTAACAGTATAGAAGTG
ATGCCAACCTCTCAGGCTTGGGATAACTTTAAAATAATTAAGCATCCCTAA

Upstream 100 bases:

>100_bases
ATATTAAGATCTGGCTCTAACTTTTTTAACTCTTGAACAGTAGCTTATTAGACAGACGGAGAATAACGCGTAATGCACAA
TACCTAATAAGGAATTTTCT

Downstream 100 bases:

>100_bases
CGAGATCAATTTAGTGGTTGGTAGTCTGCTGGCTAGCAACGCTAGAAAGCCCCCCTTTAATTAACTTATACCAACCCGCA
TAAGTAAATGGTCTAAAATT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNTKLMPTVLITGATSGFGLATAKKFAQHGYPLIITGRRKERLQKLSDQLSPITDVFFYQLDVRDSEAIKTFTQAIPDNF
KQVSILVNNAGLALGTESADKASLDDWHTMIDTNVTGLVNVTHSLLPILRKQASASIINLASIAANWSYPGSHVYGASKA
FVAQFSRNLRSDFAGTGVRVTSLEPGLSESEFSLVRFKGDKEKYQQIYNNADALQPEDIANIIFWIAEQPAHININSIEV
MPTSQAWDNFKIIKHP

Sequences:

>Translated_256_residues
MNTKLMPTVLITGATSGFGLATAKKFAQHGYPLIITGRRKERLQKLSDQLSPITDVFFYQLDVRDSEAIKTFTQAIPDNF
KQVSILVNNAGLALGTESADKASLDDWHTMIDTNVTGLVNVTHSLLPILRKQASASIINLASIAANWSYPGSHVYGASKA
FVAQFSRNLRSDFAGTGVRVTSLEPGLSESEFSLVRFKGDKEKYQQIYNNADALQPEDIANIIFWIAEQPAHININSIEV
MPTSQAWDNFKIIKHP
>Mature_256_residues
MNTKLMPTVLITGATSGFGLATAKKFAQHGYPLIITGRRKERLQKLSDQLSPITDVFFYQLDVRDSEAIKTFTQAIPDNF
KQVSILVNNAGLALGTESADKASLDDWHTMIDTNVTGLVNVTHSLLPILRKQASASIINLASIAANWSYPGSHVYGASKA
FVAQFSRNLRSDFAGTGVRVTSLEPGLSESEFSLVRFKGDKEKYQQIYNNADALQPEDIANIIFWIAEQPAHININSIEV
MPTSQAWDNFKIIKHP

Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=30.0813008130081, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI7706318, Length=265, Percent_Identity=27.5471698113208, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI20149619, Length=221, Percent_Identity=31.6742081447964, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI150247226, Length=184, Percent_Identity=33.1521739130435, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI19923817, Length=243, Percent_Identity=24.2798353909465, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40548397, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI214010158, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI214010156, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI22758144, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI22507405, Length=180, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI32483357, Length=239, Percent_Identity=25.5230125523013, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI19743808, Length=222, Percent_Identity=30.6306306306306, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705855, Length=196, Percent_Identity=26.0204081632653, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI157739938, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI119392083, Length=202, Percent_Identity=29.7029702970297, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI166795268, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI226371731, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI44680136, Length=191, Percent_Identity=30.3664921465969, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI44680133, Length=191, Percent_Identity=30.3664921465969, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI17738292, Length=191, Percent_Identity=30.3664921465969, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI186928839, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4758504, Length=189, Percent_Identity=26.4550264550265, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI225579078, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI31542939, Length=239, Percent_Identity=25.5230125523013, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723750, Length=239, Percent_Identity=23.0125523012552, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=25.1046025104602, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4504503, Length=182, Percent_Identity=26.3736263736264, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4557649, Length=179, Percent_Identity=26.2569832402235, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40254992, Length=187, Percent_Identity=25.1336898395722, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=28.7958115183246, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787820, Length=245, Percent_Identity=50.2040816326531, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI87082100, Length=185, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=28.8065843621399, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=28.1914893617021, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367175, Length=232, Percent_Identity=25.4310344827586, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=29.0816326530612, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=243, Percent_Identity=30.0411522633745, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=242, Percent_Identity=31.404958677686, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=236, Percent_Identity=28.3898305084746, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=239, Percent_Identity=29.2887029288703, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=247, Percent_Identity=29.9595141700405, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=29.7872340425532, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=245, Percent_Identity=28.1632653061224, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=28.6307053941909, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=240, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=240, Percent_Identity=30, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=237, Percent_Identity=28.2700421940928, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=241, Percent_Identity=28.2157676348548, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=241, Percent_Identity=27.8008298755187, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=239, Percent_Identity=27.1966527196653, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=27.8388278388278, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=238, Percent_Identity=28.9915966386555, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=247, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=241, Percent_Identity=24.896265560166, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=281, Percent_Identity=27.4021352313167, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=243, Percent_Identity=26.7489711934156, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=232, Percent_Identity=26.2931034482759, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=229, Percent_Identity=26.6375545851528, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=181, Percent_Identity=27.6243093922652, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=230, Percent_Identity=27.8260869565217, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=235, Percent_Identity=22.9787234042553, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=180, Percent_Identity=29.4444444444444, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=238, Percent_Identity=24.7899159663866, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=260, Percent_Identity=25.7692307692308, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=260, Percent_Identity=25.7692307692308, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193210355, Length=182, Percent_Identity=26.3736263736264, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=40.4081632653061, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322067, Length=178, Percent_Identity=30.3370786516854, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=233, Percent_Identity=24.4635193133047, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007236, Length=252, Percent_Identity=28.968253968254, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644339, Length=226, Percent_Identity=29.2035398230088, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21358495, Length=223, Percent_Identity=28.6995515695067, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357041, Length=207, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=225, Percent_Identity=29.7777777777778, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI23397609, Length=179, Percent_Identity=34.0782122905028, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643142, Length=178, Percent_Identity=33.1460674157303, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45553409, Length=198, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24647948, Length=198, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24647946, Length=198, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=25.4166666666667, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640442, Length=204, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648944, Length=236, Percent_Identity=23.728813559322, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=28.8065843621399, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24584748, Length=179, Percent_Identity=26.8156424581006, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641388, Length=257, Percent_Identity=27.6264591439689, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076933, Length=179, Percent_Identity=26.8156424581006, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007234, Length=250, Percent_Identity=24, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281364494, Length=249, Percent_Identity=22.0883534136546, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=30.1075268817204, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737361, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574402, Length=185, Percent_Identity=28.1081081081081, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584744, Length=185, Percent_Identity=28.1081081081081, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571387, Length=240, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648693, Length=258, Percent_Identity=23.6434108527132, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355889, Length=258, Percent_Identity=23.6434108527132, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24663911, Length=248, Percent_Identity=21.3709677419355, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641232, Length=256, Percent_Identity=24.21875, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=26.1083743842365, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.276 [H]

Molecular weight: Translated: 28256; Mature: 28256

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKLMPTVLITGATSGFGLATAKKFAQHGYPLIITGRRKERLQKLSDQLSPITDVFFYQ
CCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCHHHHEEEEE
LDVRDSEAIKTFTQAIPDNFKQVSILVNNAGLALGTESADKASLDDWHTMIDTNVTGLVN
EECCCHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCCCHHHHHHHHCCCHHHHH
VTHSLLPILRKQASASIINLASIAANWSYPGSHVYGASKAFVAQFSRNLRSDFAGTGVRV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
TSLEPGLSESEFSLVRFKGDKEKYQQIYNNADALQPEDIANIIFWIAEQPAHININSIEV
EECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCEEECCEEEE
MPTSQAWDNFKIIKHP
EECCCCCCCEEEEECC
>Mature Secondary Structure
MNTKLMPTVLITGATSGFGLATAKKFAQHGYPLIITGRRKERLQKLSDQLSPITDVFFYQ
CCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCHHHHEEEEE
LDVRDSEAIKTFTQAIPDNFKQVSILVNNAGLALGTESADKASLDDWHTMIDTNVTGLVN
EECCCHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCCCHHHHHHHHCCCHHHHH
VTHSLLPILRKQASASIINLASIAANWSYPGSHVYGASKAFVAQFSRNLRSDFAGTGVRV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
TSLEPGLSESEFSLVRFKGDKEKYQQIYNNADALQPEDIANIIFWIAEQPAHININSIEV
EECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCEEECCEEEE
MPTSQAWDNFKIIKHP
EECCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]