| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is fabG [H]
Identifier: 119871452
GI number: 119871452
Start: 5661016
End: 5661810
Strand: Direct
Name: fabG [H]
Synonym: Mkms_5428
Alternate gene names: 119871452
Gene position: 5661016-5661810 (Clockwise)
Preceding gene: 119871449
Following gene: 119871453
Centisome position: 98.67
GC content: 67.8
Gene sequence:
>795_bases ATGAGCACCCCGATCGTCGCTCCAGAAGTACCCACCGCACCCATCCTGGACCTCGCCGGCAAGACCGCCGTCATCACCGG CGGCAGCAAGGGCATCGGCGCGGCCACCGTGGCCCGGTTCGTCAAAGGGGGAGCTCGCGTCGTCACCTCCGGTCGCGCAC AACCGAAGTCACTGCCCTCGGGGGTGGAGTACGTGGTTGCCGACGTGAGCACTGTCGACGGTGTCGACCAATTGGCTCGA CGTGCCCGGGATGTCCTCGGCGACATCGACATCATCGTCAACAACGCCGGAGCGTCGACACCGCATCTCGGCGGCGTCCT CGACATCGACGACGCCGAGTGGGTCAAAGATCTCCACATCAACTTCCTGGCCGCCGTCCGGCTCAATGCCGCACTACTAC CCGCGCTGTACGCCCGCGGCAAGGGCTCGATCATCAATGTGTCTTCGGCCGCGACGCTGAGTCCGCCCTCGACGATGCTG CACTACGCCAGCGCCAAAGCGGCCCTGGCCACGTACACCACAGGCCTTGCCGCCGAGGCCGGGCCGCGCGGAGTGCGGGT CAACACCATCACCCCCGGAAACGTCGCCTCACCGGGTGCGGATGCCATTCGACGAGCGCTCACCGAGGCCGGGGACGTCG ACAGCCCAGCGGCCGGTGGCATGCCGATCCCGCTCGGCCGGAAGGGCGAAGCGTCCGACATCGCCGAGGCCATCGCATTT CTCGCCTCCGACCGGGCGGCGTGGATCACCGCGAGCGACCTCCTCGTCGATGGCGGCCAGATGCAGACCAGATAG
Upstream 100 bases:
>100_bases CCCGCACCCGGTTGCGCCGACTGTAGTTATGTACTAGACAGTACATAACAGCTCGGTGGCGTGGCCACCGGTGATCGTCA AACCCCGAAGGAGATGCCTC
Downstream 100 bases:
>100_bases CCGTTGACTCTGCCCTTGGGTCAGGGTCGACGCTGGTCGCATGACGAACCCACACGCGACCACCTCGGCCTGGCGTGGCA TGGTGCCGGTGGAAGACACC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 264; Mature: 263
Protein sequence:
>264_residues MSTPIVAPEVPTAPILDLAGKTAVITGGSKGIGAATVARFVKGGARVVTSGRAQPKSLPSGVEYVVADVSTVDGVDQLAR RARDVLGDIDIIVNNAGASTPHLGGVLDIDDAEWVKDLHINFLAAVRLNAALLPALYARGKGSIINVSSAATLSPPSTML HYASAKAALATYTTGLAAEAGPRGVRVNTITPGNVASPGADAIRRALTEAGDVDSPAAGGMPIPLGRKGEASDIAEAIAF LASDRAAWITASDLLVDGGQMQTR
Sequences:
>Translated_264_residues MSTPIVAPEVPTAPILDLAGKTAVITGGSKGIGAATVARFVKGGARVVTSGRAQPKSLPSGVEYVVADVSTVDGVDQLAR RARDVLGDIDIIVNNAGASTPHLGGVLDIDDAEWVKDLHINFLAAVRLNAALLPALYARGKGSIINVSSAATLSPPSTML HYASAKAALATYTTGLAAEAGPRGVRVNTITPGNVASPGADAIRRALTEAGDVDSPAAGGMPIPLGRKGEASDIAEAIAF LASDRAAWITASDLLVDGGQMQTR >Mature_263_residues STPIVAPEVPTAPILDLAGKTAVITGGSKGIGAATVARFVKGGARVVTSGRAQPKSLPSGVEYVVADVSTVDGVDQLARR ARDVLGDIDIIVNNAGASTPHLGGVLDIDDAEWVKDLHINFLAAVRLNAALLPALYARGKGSIINVSSAATLSPPSTMLH YASAKAALATYTTGLAAEAGPRGVRVNTITPGNVASPGADAIRRALTEAGDVDSPAAGGMPIPLGRKGEASDIAEAIAFL ASDRAAWITASDLLVDGGQMQTR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=33.0677290836653, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=32.8063241106719, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=33.0434782608696, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=30.078125, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=28.6290322580645, Blast_Score=96, Evalue=5e-20, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=28.125, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=32.6530612244898, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=33.5164835164835, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=27.3469387755102, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=26.2548262548263, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=27.9527559055118, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI7705855, Length=198, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=27.807486631016, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI302344755, Length=104, Percent_Identity=39.4230769230769, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=27.6699029126214, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=213, Percent_Identity=27.2300469483568, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI142976729, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI226371731, Length=196, Percent_Identity=24.4897959183673, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=25.3807106598985, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=28.1407035175879, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4758504, Length=238, Percent_Identity=30.2521008403361, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=32, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=33.7164750957854, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=31.0756972111554, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=30.46875, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=30.46875, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=27.1653543307087, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=28.3464566929134, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=29.3172690763052, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI2367175, Length=120, Percent_Identity=37.5, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1787820, Length=191, Percent_Identity=26.7015706806283, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1786701, Length=207, Percent_Identity=28.5024154589372, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=35.3383458646617, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=35.361216730038, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=35.3846153846154, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=36.0153256704981, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=35.2490421455939, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=34.7328244274809, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=32.1033210332103, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=33.7121212121212, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=32.3308270676692, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=35.4243542435424, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=34.3283582089552, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=30.7692307692308, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=31.6981132075472, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=32.5670498084291, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=30.5970149253731, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=32.9501915708812, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=29.3893129770992, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=32.962962962963, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=32.1428571428571, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=32.2222222222222, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=30.6201550387597, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI71994604, Length=263, Percent_Identity=29.6577946768061, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=31.4176245210728, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=29.0836653386454, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=31.0861423220974, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=26.5060240963855, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=210, Percent_Identity=28.0952380952381, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=27.1317829457364, Blast_Score=75, Evalue=8e-15, Organism=Saccharomyces cerevisiae, GI6322227, Length=209, Percent_Identity=29.1866028708134, Blast_Score=70, Evalue=5e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=29.2929292929293, Blast_Score=64, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322226, Length=194, Percent_Identity=32.9896907216495, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=36.5758754863813, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=32.2709163346614, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=30.9160305343511, Blast_Score=101, Evalue=7e-22, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.5396825396825, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=31.7460317460317, Blast_Score=98, Evalue=7e-21, Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI24644337, Length=261, Percent_Identity=32.5670498084291, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=28.90625, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI21358495, Length=222, Percent_Identity=25.6756756756757, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24640442, Length=216, Percent_Identity=28.7037037037037, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24584744, Length=207, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI161076933, Length=218, Percent_Identity=26.605504587156, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI28574402, Length=207, Percent_Identity=25.6038647342995, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24584748, Length=218, Percent_Identity=26.605504587156, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=29.0598290598291, Blast_Score=71, Evalue=8e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26677; Mature: 26545
Theoretical pI: Translated: 6.27; Mature: 6.27
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTPIVAPEVPTAPILDLAGKTAVITGGSKGIGAATVARFVKGGARVVTSGRAQPKSLPS CCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCC GVEYVVADVSTVDGVDQLARRARDVLGDIDIIVNNAGASTPHLGGVLDIDDAEWVKDLHI CHHEEEECCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCHHHHHHHHHH NFLAAVRLNAALLPALYARGKGSIINVSSAATLSPPSTMLHYASAKAALATYTTGLAAEA HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC GPRGVRVNTITPGNVASPGADAIRRALTEAGDVDSPAAGGMPIPLGRKGEASDIAEAIAF CCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH LASDRAAWITASDLLVDGGQMQTR HHCCCCEEEEEHHEEEECCCCCCC >Mature Secondary Structure STPIVAPEVPTAPILDLAGKTAVITGGSKGIGAATVARFVKGGARVVTSGRAQPKSLPS CCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCC GVEYVVADVSTVDGVDQLARRARDVLGDIDIIVNNAGASTPHLGGVLDIDDAEWVKDLHI CHHEEEECCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCHHHHHHHHHH NFLAAVRLNAALLPALYARGKGSIINVSSAATLSPPSTMLHYASAKAALATYTTGLAAEA HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC GPRGVRVNTITPGNVASPGADAIRRALTEAGDVDSPAAGGMPIPLGRKGEASDIAEAIAF CCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH LASDRAAWITASDLLVDGGQMQTR HHCCCCEEEEEHHEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]