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The map label for this gene is trxB [H]

Identifier: 119871309

GI number: 119871309

Start: 5517532

End: 5518599

Strand: Direct

Name: trxB [H]

Synonym: Mkms_5282

Alternate gene names: 119871309

Gene position: 5517532-5518599 (Clockwise)

Preceding gene: 119871308

Following gene: 119871310

Centisome position: 96.17

GC content: 68.73

Gene sequence:

>1068_bases
ATGCTGTGCTCGTTTTCGACACCACGGTCGTGGTTCCGGTGGCCGGACTCGCCGTCAACGACCCTGGTGTCGAATCTGCG
CACAAGGCGTCGATTGTTTGATCACCCCGCCTCCCGGGAATCGGTCGGGGCAATGACACACGAATGGGAATGCGTCGTCG
TCGGTGGTGGCGCGGCGGGATTGAGCGCCACCCTGGTCCTGGGACGGGCGCGCCGACGCACCCTGCTCGTCGACGCGGGT
GAACAGAGCAACAGGGTCTCCACCGGCATCGGCGGATTGCTCGGCTACGACCAGCGGCCGCCGGCGGAGCTGTACGAGAC
GGGCCGACGCGAGCTCGAGGCGTATCCGACGGTCGAGTACCGGGTGGGCACCGTGGTGCACGGAGCCGCGCAGGACGACG
GCTTCGTGCTCTCCCTCGACGACGGTGATCGGGTCACCACCCGGCGGGTGCTGCTGGCCACCGGCATGGAGTACTGCCCG
CCGGAGCTGCCGGGCCTGGAACCGCTTTGGGGTAAGTCCGTGTTCCAGTGTCCGTTCTGCCACGGCTGGGAGATGCGCGA
CAAGCGGATCGCCTCCTTGGCCGCGGGTGAGGAGGCCGTGCACTCGGCGCTGATGCTGCGCGGGTGGAGCGACGACGTGG
TGCTGCTCACCGACGGCCATCCGCAACTCGACGGCAGGGACATCGATCAGTTGAAGGCCGCGGACATCATCGTCGACGAC
CGCCGGATCGCCGAACTGATCGGCACCGACGGACAGCTGACCGCGATCGCGTTCAACGACGGAAGCCGGTTGGAACGCGA
CGGTCTGCTCGTCGAGGCCCCGCTGCGGCAGCGTTCGAAACTCGCCGAGCAACTGGGCGCCACCTGCACGCCGGGTCCGC
TGGCCCAGGACACCATCGGCATCGACGCGCTGCACCGCACGTCGGCGCACACGGTGTTCGCCGCCGGTGACGTGTGCACC
GAACACCCGTACGTGGCCGGGTCGATCGCAGGGGGTGCGCAGGCGGCGATGATCGTCGCGCAGAGCCTGCTGGCCGAGCA
GTTCGGGATGCCGTACCCGCCGGAGTGA

Upstream 100 bases:

>100_bases
CGAGCACGGCTACATCGTGCCGGGGCTCGGCGATGCGGGTGACCGGATCTTCGGCACCAAGTAGCGCCGCCCCGGCTCCC
CTGAAGGGGTGTCGTCGCGG

Downstream 100 bases:

>100_bases
CCATTGACAGGTGTCTCGGGGCATTGTTTTGGTGAGCAGGTGACCGCACCGAAACCGCTTTCGATCGAGAACTTCTCGCA
CATATGTGTCGGCGTTTCAG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MLCSFSTPRSWFRWPDSPSTTLVSNLRTRRRLFDHPASRESVGAMTHEWECVVVGGGAAGLSATLVLGRARRRTLLVDAG
EQSNRVSTGIGGLLGYDQRPPAELYETGRRELEAYPTVEYRVGTVVHGAAQDDGFVLSLDDGDRVTTRRVLLATGMEYCP
PELPGLEPLWGKSVFQCPFCHGWEMRDKRIASLAAGEEAVHSALMLRGWSDDVVLLTDGHPQLDGRDIDQLKAADIIVDD
RRIAELIGTDGQLTAIAFNDGSRLERDGLLVEAPLRQRSKLAEQLGATCTPGPLAQDTIGIDALHRTSAHTVFAAGDVCT
EHPYVAGSIAGGAQAAMIVAQSLLAEQFGMPYPPE

Sequences:

>Translated_355_residues
MLCSFSTPRSWFRWPDSPSTTLVSNLRTRRRLFDHPASRESVGAMTHEWECVVVGGGAAGLSATLVLGRARRRTLLVDAG
EQSNRVSTGIGGLLGYDQRPPAELYETGRRELEAYPTVEYRVGTVVHGAAQDDGFVLSLDDGDRVTTRRVLLATGMEYCP
PELPGLEPLWGKSVFQCPFCHGWEMRDKRIASLAAGEEAVHSALMLRGWSDDVVLLTDGHPQLDGRDIDQLKAADIIVDD
RRIAELIGTDGQLTAIAFNDGSRLERDGLLVEAPLRQRSKLAEQLGATCTPGPLAQDTIGIDALHRTSAHTVFAAGDVCT
EHPYVAGSIAGGAQAAMIVAQSLLAEQFGMPYPPE
>Mature_355_residues
MLCSFSTPRSWFRWPDSPSTTLVSNLRTRRRLFDHPASRESVGAMTHEWECVVVGGGAAGLSATLVLGRARRRTLLVDAG
EQSNRVSTGIGGLLGYDQRPPAELYETGRRELEAYPTVEYRVGTVVHGAAQDDGFVLSLDDGDRVTTRRVLLATGMEYCP
PELPGLEPLWGKSVFQCPFCHGWEMRDKRIASLAAGEEAVHSALMLRGWSDDVVLLTDGHPQLDGRDIDQLKAADIIVDD
RRIAELIGTDGQLTAIAFNDGSRLERDGLLVEAPLRQRSKLAEQLGATCTPGPLAQDTIGIDALHRTSAHTVFAAGDVCT
EHPYVAGSIAGGAQAAMIVAQSLLAEQFGMPYPPE

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=207, Percent_Identity=28.5024154589372, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 38431; Mature: 38431

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCSFSTPRSWFRWPDSPSTTLVSNLRTRRRLFDHPASRESVGAMTHEWECVVVGGGAAG
CCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCCCC
LSATLVLGRARRRTLLVDAGEQSNRVSTGIGGLLGYDQRPPAELYETGRRELEAYPTVEY
HHHHHHHHHCCCEEEEEECCCCCCCCHHCCCHHCCCCCCCCHHHHHCCHHHHHCCCCEEE
RVGTVVHGAAQDDGFVLSLDDGDRVTTRRVLLATGMEYCPPELPGLEPLWGKSVFQCPFC
EECEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEECCCC
HGWEMRDKRIASLAAGEEAVHSALMLRGWSDDVVLLTDGHPQLDGRDIDQLKAADIIVDD
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHEEECC
RRIAELIGTDGQLTAIAFNDGSRLERDGLLVEAPLRQRSKLAEQLGATCTPGPLAQDTIG
HHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHCC
IDALHRTSAHTVFAAGDVCTEHPYVAGSIAGGAQAAMIVAQSLLAEQFGMPYPPE
HHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLCSFSTPRSWFRWPDSPSTTLVSNLRTRRRLFDHPASRESVGAMTHEWECVVVGGGAAG
CCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCCCC
LSATLVLGRARRRTLLVDAGEQSNRVSTGIGGLLGYDQRPPAELYETGRRELEAYPTVEY
HHHHHHHHHCCCEEEEEECCCCCCCCHHCCCHHCCCCCCCCHHHHHCCHHHHHCCCCEEE
RVGTVVHGAAQDDGFVLSLDDGDRVTTRRVLLATGMEYCPPELPGLEPLWGKSVFQCPFC
EECEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEECCCC
HGWEMRDKRIASLAAGEEAVHSALMLRGWSDDVVLLTDGHPQLDGRDIDQLKAADIIVDD
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHEEECC
RRIAELIGTDGQLTAIAFNDGSRLERDGLLVEAPLRQRSKLAEQLGATCTPGPLAQDTIG
HHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHCC
IDALHRTSAHTVFAAGDVCTEHPYVAGSIAGGAQAAMIVAQSLLAEQFGMPYPPE
HHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA