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The map label for this gene is dprE1 [H]

Identifier: 119871115

GI number: 119871115

Start: 5322889

End: 5324259

Strand: Direct

Name: dprE1 [H]

Synonym: Mkms_5088

Alternate gene names: 119871115

Gene position: 5322889-5324259 (Clockwise)

Preceding gene: 119871114

Following gene: 119871116

Centisome position: 92.78

GC content: 66.89

Gene sequence:

>1371_bases
ATGTTGCAGACCACGACCCGGCGGCTCACCGGATGGGCCCGCACCGCGCCATCCGTGGCCGAGGTGCTGTCGACGCCCGA
CCCCGAGGAGATCGCCAAGGCGGTCGCGCGGGTTGCCGACGATCCGCAGCGCGGCGTCATCGCCCGCGGACTGGGCCGCT
CCTACGGTGACAACGCGCAGAACGGCGGCGGCCTGGTCGTCGACATGACCGCGCTCAACCGCATCCACACCATCAACACC
GACACCGCGCTCGTCGACGTCGACGCCGGGGTGAATCTCGACCAGCTGATGCGCGCGGCGCTACCGCTCGGCCTGTGGGT
CCCGGTGCTGCCCGGCACCCGTCAGGTCACCGTCGGTGGCGCGATCGCCTGCGACATCCACGGCAAGAACCACCACAGCG
CGGGCAGCTTCGGCAACCACGTCCGCTCGATGGAGCTGCTCACCGCCGACGGCACCGTGCGCACCCTCAAACCCCGCGGC
AAGGACGCCGACCTGTTCTGGGCCACCGTCGGCGGCAACGGGCTGACCGGCATCATCCTGCGCGCCACCATCGCGATGAC
GCCGACGGAGACCGCGTACTTCATCGCCGACGGTGACGTCACCGCCGACCTGGACGAGACCATCGCGATCCACAGCGACG
GCAGCGAGGCGAACTACACCTACTCCAGCGCGTGGTTCGACGCGATCAGCCCGCCGCCCAAACTCGGCCGTGCCGCCATC
TCCCGCGGATCGCTGGCCACCCTCGACCAGCTACCCAAGAAGCTGCGCCGCAATCCGCTGAAATTCGATGCGCCGCAACT
GCTCACCTTCCCCGACGTGTTCCCCAACGGGTTGGCCAACAAGTGGACGTTCGGCCCGATCGGCGAACTGTGGTACCGCA
AATCGGGTACCTACCGCGGCAAGATCCAGAACCTGACGCAGTTCTATCACCCGCTCGACATGTTCGGTGAGTGGAACCGC
GCCTACGGCAGCAACGGATTCCTGCAGTACCAGTTCGTGGTGCCCACCGAGGCGGTCGACGAGTTCAAGGCCATCCTCGT
CGACATCCAGCGTTCCGGGCACTACTCGTTCCTCAACGTGTTCAAACTGTTCGGACCGGGAAACAAAGCGCCGCTGAGCT
TTCCGATCCCAGGATGGAACGTCTGCGTCGACTTCCCGATCAAACCGGGGTTGGGCGAGTTCGTCAGCGGACTCGACCAC
CGGGTGCTGCAGTTCGGCGGCCGGCTCTACACCGCCAAGGACTCCCGCACCACCGCCGAAACCTTCCACGCCATGTACCC
GCGCATCGACGAGTGGATCGCCGTGCGCCGCCGGGTCGATCCCGACGGGGTGTTCGCCTCCGACATGGCCCGACGTTTGG
AGCTGCTCTAA

Upstream 100 bases:

>100_bases
TCAACTTCGTCGTCCAGCGCGCGGTGATCTTCCGGTGGGCAGGAGCGCAGCGACTCGGGGATGAATAGGAGGCTCCGGTA
GGGGCGGTACCCTCGTCACG

Downstream 100 bases:

>100_bases
ATGGTGCTTGACGCCGTGGGGAACCCCCAGACCATCCTGTTGCTCGGCGGGACCTCCGAGATCGGGCTGGCGATCTGCGA
GCGCTACCTGCGCGACGCGC

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLQTTTRRLTGWARTAPSVAEVLSTPDPEEIAKAVARVADDPQRGVIARGLGRSYGDNAQNGGGLVVDMTALNRIHTINT
DTALVDVDAGVNLDQLMRAALPLGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMELLTADGTVRTLKPRG
KDADLFWATVGGNGLTGIILRATIAMTPTETAYFIADGDVTADLDETIAIHSDGSEANYTYSSAWFDAISPPPKLGRAAI
SRGSLATLDQLPKKLRRNPLKFDAPQLLTFPDVFPNGLANKWTFGPIGELWYRKSGTYRGKIQNLTQFYHPLDMFGEWNR
AYGSNGFLQYQFVVPTEAVDEFKAILVDIQRSGHYSFLNVFKLFGPGNKAPLSFPIPGWNVCVDFPIKPGLGEFVSGLDH
RVLQFGGRLYTAKDSRTTAETFHAMYPRIDEWIAVRRRVDPDGVFASDMARRLELL

Sequences:

>Translated_456_residues
MLQTTTRRLTGWARTAPSVAEVLSTPDPEEIAKAVARVADDPQRGVIARGLGRSYGDNAQNGGGLVVDMTALNRIHTINT
DTALVDVDAGVNLDQLMRAALPLGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMELLTADGTVRTLKPRG
KDADLFWATVGGNGLTGIILRATIAMTPTETAYFIADGDVTADLDETIAIHSDGSEANYTYSSAWFDAISPPPKLGRAAI
SRGSLATLDQLPKKLRRNPLKFDAPQLLTFPDVFPNGLANKWTFGPIGELWYRKSGTYRGKIQNLTQFYHPLDMFGEWNR
AYGSNGFLQYQFVVPTEAVDEFKAILVDIQRSGHYSFLNVFKLFGPGNKAPLSFPIPGWNVCVDFPIKPGLGEFVSGLDH
RVLQFGGRLYTAKDSRTTAETFHAMYPRIDEWIAVRRRVDPDGVFASDMARRLELL
>Mature_456_residues
MLQTTTRRLTGWARTAPSVAEVLSTPDPEEIAKAVARVADDPQRGVIARGLGRSYGDNAQNGGGLVVDMTALNRIHTINT
DTALVDVDAGVNLDQLMRAALPLGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMELLTADGTVRTLKPRG
KDADLFWATVGGNGLTGIILRATIAMTPTETAYFIADGDVTADLDETIAIHSDGSEANYTYSSAWFDAISPPPKLGRAAI
SRGSLATLDQLPKKLRRNPLKFDAPQLLTFPDVFPNGLANKWTFGPIGELWYRKSGTYRGKIQNLTQFYHPLDMFGEWNR
AYGSNGFLQYQFVVPTEAVDEFKAILVDIQRSGHYSFLNVFKLFGPGNKAPLSFPIPGWNVCVDFPIKPGLGEFVSGLDH
RVLQFGGRLYTAKDSRTTAETFHAMYPRIDEWIAVRRRVDPDGVFASDMARRLELL

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49914; Mature: 49914

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTTTRRLTGWARTAPSVAEVLSTPDPEEIAKAVARVADDPQRGVIARGLGRSYGDNAQ
CCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC
NGGGLVVDMTALNRIHTINTDTALVDVDAGVNLDQLMRAALPLGLWVPVLPGTRQVTVGG
CCCCEEEEEECCCEEEEECCCCEEEEECCCCCHHHHHHHHCCCCEEEECCCCCEEEEECC
AIACDIHGKNHHSAGSFGNHVRSMELLTADGTVRTLKPRGKDADLFWATVGGNGLTGIIL
EEEEEECCCCCCCCCCHHHHHHEEEEEECCCCEEEECCCCCCCCEEEEEECCCCCEEEEE
RATIAMTPTETAYFIADGDVTADLDETIAIHSDGSEANYTYSSAWFDAISPPPKLGRAAI
EEEEEECCCCCEEEEECCCEEECCCCEEEEECCCCCCCEEEHHHHHCCCCCCHHHHHHHH
SRGSLATLDQLPKKLRRNPLKFDAPQLLTFPDVFPNGLANKWTFGPIGELWYRKSGTYRG
CCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCH
KIQNLTQFYHPLDMFGEWNRAYGSNGFLQYQFVVPTEAVDEFKAILVDIQRSGHYSFLNV
HHHHHHHHHCCHHHHCCHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHH
FKLFGPGNKAPLSFPIPGWNVCVDFPIKPGLGEFVSGLDHRVLQFGGRLYTAKDSRTTAE
HHHHCCCCCCCEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHH
TFHAMYPRIDEWIAVRRRVDPDGVFASDMARRLELL
HHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLQTTTRRLTGWARTAPSVAEVLSTPDPEEIAKAVARVADDPQRGVIARGLGRSYGDNAQ
CCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC
NGGGLVVDMTALNRIHTINTDTALVDVDAGVNLDQLMRAALPLGLWVPVLPGTRQVTVGG
CCCCEEEEEECCCEEEEECCCCEEEEECCCCCHHHHHHHHCCCCEEEECCCCCEEEEECC
AIACDIHGKNHHSAGSFGNHVRSMELLTADGTVRTLKPRGKDADLFWATVGGNGLTGIIL
EEEEEECCCCCCCCCCHHHHHHEEEEEECCCCEEEECCCCCCCCEEEEEECCCCCEEEEE
RATIAMTPTETAYFIADGDVTADLDETIAIHSDGSEANYTYSSAWFDAISPPPKLGRAAI
EEEEEECCCCCEEEEECCCEEECCCCEEEEECCCCCCCEEEHHHHHCCCCCCHHHHHHHH
SRGSLATLDQLPKKLRRNPLKFDAPQLLTFPDVFPNGLANKWTFGPIGELWYRKSGTYRG
CCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCH
KIQNLTQFYHPLDMFGEWNRAYGSNGFLQYQFVVPTEAVDEFKAILVDIQRSGHYSFLNV
HHHHHHHHHCCHHHHCCHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHH
FKLFGPGNKAPLSFPIPGWNVCVDFPIKPGLGEFVSGLDHRVLQFGGRLYTAKDSRTTAE
HHHHCCCCCCCEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHH
TFHAMYPRIDEWIAVRRRVDPDGVFASDMARRLELL
HHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]