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The map label for this gene is exoB [H]

Identifier: 119870903

GI number: 119870903

Start: 5106934

End: 5107923

Strand: Direct

Name: exoB [H]

Synonym: Mkms_4875

Alternate gene names: 119870903

Gene position: 5106934-5107923 (Clockwise)

Preceding gene: 119870902

Following gene: 119870904

Centisome position: 89.01

GC content: 70.0

Gene sequence:

>990_bases
ATGACCTGGCTCGTGACCGGCGGCGCCGGCTACATCGGCTCGCACGTCGTCCGGGCGTTGACCGAGGCCGACCTGCCGGT
CGTCGTGATCGACGACCTGTCCACCGGGCTCGAGCAGTTCGTACCGGAATCCGTGCCGTTCGTCCGCGGCACCCTGCTCG
ACGGCGCCCTCGTCGAACAGACGCTACGCGAACACGCGGTCGCCGGGGTCATCCACATCGCCGGGTTCAAATACGCCGGG
GTGTCGGTCCAGCGGCCCCTGCACACCTATGAGCAGAACGTGTCGGCGATGGTGACGCTGCTGCAGGCGATGGAGACCGT
CGGCGTCGACAAGATCGTGTTCTCCTCCAGCGCAGCCACATTCGGCACACCGGATGTCGATCAGGTGGACGAGTCCACGC
CGACCGCCCCGGAATCGCCCTACGGCGAGACCAAGCTGATCGGCGAGTGGCTGCTGCGCGACATGGGCCGTGCGTCGGGT
CTGCGCCACACCAGCCTGCGGTACTTCAACGTTGTCGGCTCCGGCTCGACCGCGCTGTTCGACACCAGCCCGCACAACCT
GTTCCCGCTGGTGTTCGACATGCTCTACCGCGGCGACACGCCCCGCATCAACGGCGACGACTACCCCACCCCGGACGGCA
CCTGCGTGCGCGACTACGTCGACGTCGGCGACGTCGCGCTGGCGCACGTCGCCGCGGCCCGTCGGCTCACCCGCGGCGAA
CCGGTGGAACCGGTGTACAACCTCGGCAGCGGGGCGGGCACCTCGGTGCGCGAGATCATGACCGCCATCCGCACGGTCAC
CGGCGTCGACTTCGAGCCGCAGATCATGCCGCGGCGGCCGGGCGACCCGGCGCGGATCGTGGCCAACGGCGACCTCGCCG
CACGGGACCTGGACTGGAAGATGCGCCACTCGCTGGAGGACATGGTGGCCTCGGCGTGGGCGGCGCGCCAGGCGGCCGGT
GCCGCCTATCCGGGAGCGGGACAGTCCTGA

Upstream 100 bases:

>100_bases
TGCTGTGCGGTCCGCTGGTCGGGATCGCCGTGCACCTCGCCGGACTTGCGGGCGCACCGGACCGCACGCATATCCTGCGT
TCTCGACGAAGGAGGGCTCC

Downstream 100 bases:

>100_bases
ACCGTGTTGCCCGCGCCGCCGTCGGCCTGATCGCGGTGCACCTGGTCGTCCGGGCGGTGCTGGCGTTCGGCGGCTACTTC
TACTGGGACGACCTGATCCT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTWLVTGGAGYIGSHVVRALTEADLPVVVIDDLSTGLEQFVPESVPFVRGTLLDGALVEQTLREHAVAGVIHIAGFKYAG
VSVQRPLHTYEQNVSAMVTLLQAMETVGVDKIVFSSSAATFGTPDVDQVDESTPTAPESPYGETKLIGEWLLRDMGRASG
LRHTSLRYFNVVGSGSTALFDTSPHNLFPLVFDMLYRGDTPRINGDDYPTPDGTCVRDYVDVGDVALAHVAAARRLTRGE
PVEPVYNLGSGAGTSVREIMTAIRTVTGVDFEPQIMPRRPGDPARIVANGDLAARDLDWKMRHSLEDMVASAWAARQAAG
AAYPGAGQS

Sequences:

>Translated_329_residues
MTWLVTGGAGYIGSHVVRALTEADLPVVVIDDLSTGLEQFVPESVPFVRGTLLDGALVEQTLREHAVAGVIHIAGFKYAG
VSVQRPLHTYEQNVSAMVTLLQAMETVGVDKIVFSSSAATFGTPDVDQVDESTPTAPESPYGETKLIGEWLLRDMGRASG
LRHTSLRYFNVVGSGSTALFDTSPHNLFPLVFDMLYRGDTPRINGDDYPTPDGTCVRDYVDVGDVALAHVAAARRLTRGE
PVEPVYNLGSGAGTSVREIMTAIRTVTGVDFEPQIMPRRPGDPARIVANGDLAARDLDWKMRHSLEDMVASAWAARQAAG
AAYPGAGQS
>Mature_328_residues
TWLVTGGAGYIGSHVVRALTEADLPVVVIDDLSTGLEQFVPESVPFVRGTLLDGALVEQTLREHAVAGVIHIAGFKYAGV
SVQRPLHTYEQNVSAMVTLLQAMETVGVDKIVFSSSAATFGTPDVDQVDESTPTAPESPYGETKLIGEWLLRDMGRASGL
RHTSLRYFNVVGSGSTALFDTSPHNLFPLVFDMLYRGDTPRINGDDYPTPDGTCVRDYVDVGDVALAHVAAARRLTRGEP
VEPVYNLGSGAGTSVREIMTAIRTVTGVDFEPQIMPRRPGDPARIVANGDLAARDLDWKMRHSLEDMVASAWAARQAAGA
AYPGAGQS

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=330, Percent_Identity=36.0606060606061, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI56118217, Length=330, Percent_Identity=36.0606060606061, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI189083684, Length=330, Percent_Identity=36.0606060606061, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=25.1824817518248, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=37.1681415929204, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI48994969, Length=363, Percent_Identity=25.8953168044077, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=336, Percent_Identity=36.6071428571429, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71982038, Length=338, Percent_Identity=36.3905325443787, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17568069, Length=301, Percent_Identity=25.9136212624585, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=331, Percent_Identity=36.5558912386707, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI19923002, Length=333, Percent_Identity=34.5345345345345, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35256; Mature: 35125

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWLVTGGAGYIGSHVVRALTEADLPVVVIDDLSTGLEQFVPESVPFVRGTLLDGALVEQ
CEEEEECCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TLREHAVAGVIHIAGFKYAGVSVQRPLHTYEQNVSAMVTLLQAMETVGVDKIVFSSSAAT
HHHHHHHHHHHHHCCCEECCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCC
FGTPDVDQVDESTPTAPESPYGETKLIGEWLLRDMGRASGLRHTSLRYFNVVGSGSTALF
CCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEE
DTSPHNLFPLVFDMLYRGDTPRINGDDYPTPDGTCVRDYVDVGDVALAHVAAARRLTRGE
ECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PVEPVYNLGSGAGTSVREIMTAIRTVTGVDFEPQIMPRRPGDPARIVANGDLAARDLDWK
CCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEECCCCCHH
MRHSLEDMVASAWAARQAAGAAYPGAGQS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TWLVTGGAGYIGSHVVRALTEADLPVVVIDDLSTGLEQFVPESVPFVRGTLLDGALVEQ
EEEEECCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TLREHAVAGVIHIAGFKYAGVSVQRPLHTYEQNVSAMVTLLQAMETVGVDKIVFSSSAAT
HHHHHHHHHHHHHCCCEECCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCC
FGTPDVDQVDESTPTAPESPYGETKLIGEWLLRDMGRASGLRHTSLRYFNVVGSGSTALF
CCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEE
DTSPHNLFPLVFDMLYRGDTPRINGDDYPTPDGTCVRDYVDVGDVALAHVAAARRLTRGE
ECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PVEPVYNLGSGAGTSVREIMTAIRTVTGVDFEPQIMPRRPGDPARIVANGDLAARDLDWK
CCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEECCCCCHH
MRHSLEDMVASAWAARQAAGAAYPGAGQS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]