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The map label for this gene is ppa [H]

Identifier: 119870893

GI number: 119870893

Start: 5093687

End: 5094175

Strand: Direct

Name: ppa [H]

Synonym: Mkms_4865

Alternate gene names: 119870893

Gene position: 5093687-5094175 (Clockwise)

Preceding gene: 119870888

Following gene: 119870894

Centisome position: 88.78

GC content: 66.05

Gene sequence:

>489_bases
GTGGAGTTCGAGGTCGTCATCGAGATCCCCAAGGGGTCACGCAACAAGTACGAGGTCGACCACGAGACCGGCCGGCTCAA
ACTGGACCGCTACCTCTACACGTCGATGGCCTACCCGACCGACTACGGCTTCATCGAGAACTCGCTCGGCGAGGACGGCG
ACCCACTCGACGCGCTGGTACTGCTGCCCGAGTCGGTGTTCCCCGGCTGCATCGTCGACGCCCGTCCGGTGGCGATGTTC
CAGATGACCGACGAGGCCGGCGGCGACGACAAGGTGCTCTGCGTACCGGCCGGCGACAAGCGCTGGGACCACATCCAGGA
CCTCGCCGACGTCCCCGAGCAGGTGCTCGAGGAGGTCAAGCACTTCTTCGTCCACTACAAGGACCTGGAGCCGAACAAGT
ACGTCAAGGCCGCCGACTGGACCGGCCGCGAGGCGGCCGAGGCCGAGGTGCAGCGGTCCTTCGAACGGTTCGAGGCCGAA
GGCCACTAG

Upstream 100 bases:

>100_bases
AACCACCCCGCCAACAGCAGCGTATCGCTCGTTTACTGTGGACCCGCGTCGTCGTCACCCGACGACCCCGGTGCGAACAC
AGACGAAGGAGCCGACTGCG

Downstream 100 bases:

>100_bases
CCCGGCCACCGAAATTATCGCGCCCGTAACACGGCGTAACGCGGTCGTGGCTTGAGGCTCCGATCATTGGCCCATGCTGA
TGCACCAGGGCATTGGCCTC

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MEFEVVIEIPKGSRNKYEVDHETGRLKLDRYLYTSMAYPTDYGFIENSLGEDGDPLDALVLLPESVFPGCIVDARPVAMF
QMTDEAGGDDKVLCVPAGDKRWDHIQDLADVPEQVLEEVKHFFVHYKDLEPNKYVKAADWTGREAAEAEVQRSFERFEAE
GH

Sequences:

>Translated_162_residues
MEFEVVIEIPKGSRNKYEVDHETGRLKLDRYLYTSMAYPTDYGFIENSLGEDGDPLDALVLLPESVFPGCIVDARPVAMF
QMTDEAGGDDKVLCVPAGDKRWDHIQDLADVPEQVLEEVKHFFVHYKDLEPNKYVKAADWTGREAAEAEVQRSFERFEAE
GH
>Mature_162_residues
MEFEVVIEIPKGSRNKYEVDHETGRLKLDRYLYTSMAYPTDYGFIENSLGEDGDPLDALVLLPESVFPGCIVDARPVAMF
QMTDEAGGDDKVLCVPAGDKRWDHIQDLADVPEQVLEEVKHFFVHYKDLEPNKYVKAADWTGREAAEAEVQRSFERFEAE
GH

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=155, Percent_Identity=49.0322580645161, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 18457; Mature: 18457

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEVVIEIPKGSRNKYEVDHETGRLKLDRYLYTSMAYPTDYGFIENSLGEDGDPLDALV
CCEEEEEECCCCCCCCEEECCCCCCEEEHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEEE
LLPESVFPGCIVDARPVAMFQMTDEAGGDDKVLCVPAGDKRWDHIQDLADVPEQVLEEVK
ECCCCCCCCCEECCCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
HFFVHYKDLEPNKYVKAADWTGREAAEAEVQRSFERFEAEGH
HHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFEVVIEIPKGSRNKYEVDHETGRLKLDRYLYTSMAYPTDYGFIENSLGEDGDPLDALV
CCEEEEEECCCCCCCCEEECCCCCCEEEHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEEE
LLPESVFPGCIVDARPVAMFQMTDEAGGDDKVLCVPAGDKRWDHIQDLADVPEQVLEEVK
ECCCCCCCCCEECCCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
HFFVHYKDLEPNKYVKAADWTGREAAEAEVQRSFERFEAEGH
HHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]