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The map label for this gene is yfdZ [C]

Identifier: 119870812

GI number: 119870812

Start: 5015394

End: 5016581

Strand: Direct

Name: yfdZ [C]

Synonym: Mkms_4784

Alternate gene names: 119870812

Gene position: 5015394-5016581 (Clockwise)

Preceding gene: 119870811

Following gene: 119870813

Centisome position: 87.42

GC content: 70.71

Gene sequence:

>1188_bases
ATGAGCGGAGCCCACGCACAACGCACCGAGCCGCGGGACGTGGCCCTACGCGCCGGCATCCCGCCGTTCTACGTGATGGA
CGTCTGGCTGGCCGCCGCGGAACGGCAACGCACCCACGGCGACCTGGTCAACCTGTCGGCCGGCCAACCGAGCGCCGGCG
CGCCGACGGCGGTGCGCGAGGCCGCCATCGCAGCGCTGCAGGAGAACCAACTGGGCTACACCGTCGCGCTCGGCATCCCG
GAACTGCGCGAGGCGATCGCCGCACGGTACGCCGACCAGTTCGGCCTGACGGTCGGGCTCGACGACGTCGTGCTGACCAC
CGGGTCGTCGGGCGGATTCCTGCTCGCGTTCCTGGCGTGCTTCGACGTGGGTGACCGGGTGGCGATCGCCAGCCCCGGCT
ACCCCTGCTACCGCAACATCCTGACCGCGCTCGGGTGCGAGGTCGTCGAGATCCCCTGCGGTGCGGACACCCGTTTCCAA
CCCACCGCCGCGATGCTCGCCGAACTCGATCCGCCGGTGCAGGGCGTGATCGTGGCAAGCCCCGCCAACCCCACCGGCAC
GGTCATCGCGCCCGCTGAACTCGCCGCGATCGCCACCTGGTGTGAGGCGACCGGCACCCGGCTGATCAGCGACGAGGTCT
ACCACGGACTCGTCTACGACGGCGCCCCGCCGATCAGCTGCGCGTGGCAGACCTCGCGCAAAGCCGTGGTGGTCAACAGC
TTTTCCAAGTACTACGCGATGACCGGGTGGCGGCTGGGCTGGCTGCTGGTGCCGCAGGAACTGCGCCGCGCCGTCGACCG
GCTCACCGGCAACTTCACTATCTGCCCGCCCGCGCTGGCTCAGCACGCCGCGGTGGCCGCGTTCACCCCGGAGTCGACCG
CGGAGGCCGACGGTCTGCTGGCCCACTACGCCGAGAACCGGCGGCTGTTGCTCGACGGGCTGCGCGCCATCGGCATCAGC
CGGCTGGCGCCCGCCGACGGCGCGTTCTACGTCTACGCCGATGTCTCGCATCTGACCGACGCCTCGTTGTCGTTCTGCGC
GAAGCTGCTGGCCGACACCGGAGTCGCGATCGCACCCGGTATCGACTTCGACACCGTGCACGGCAACTCGTTCGTCAGGC
TGTCGTTCGCCGGGCCGACGGCCGACATCACCGAGGCGTTGAGCCGCATCGGGGGCTGGCTGCGCTGA

Upstream 100 bases:

>100_bases
CAGCTGTACTTCAAGCGGGCCCACGCCAGTGCCCAACTGCTCGGCCCGCCCCGCGAGCAGCTTCGCCGCCTCGAGACACA
AGTGTTCTAGCCTCGATCTG

Downstream 100 bases:

>100_bases
CTTGTCGGGTTGTCGGTGGGCGCCGCTACAGTCGGAGCCATGTTCGAAAGTGTGTTCGATGTCGACCCCGACGCGGGTGA
GGCGGAGTTGCGCGCGCAGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSGAHAQRTEPRDVALRAGIPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPTAVREAAIAALQENQLGYTVALGIP
ELREAIAARYADQFGLTVGLDDVVLTTGSSGGFLLAFLACFDVGDRVAIASPGYPCYRNILTALGCEVVEIPCGADTRFQ
PTAAMLAELDPPVQGVIVASPANPTGTVIAPAELAAIATWCEATGTRLISDEVYHGLVYDGAPPISCAWQTSRKAVVVNS
FSKYYAMTGWRLGWLLVPQELRRAVDRLTGNFTICPPALAQHAAVAAFTPESTAEADGLLAHYAENRRLLLDGLRAIGIS
RLAPADGAFYVYADVSHLTDASLSFCAKLLADTGVAIAPGIDFDTVHGNSFVRLSFAGPTADITEALSRIGGWLR

Sequences:

>Translated_395_residues
MSGAHAQRTEPRDVALRAGIPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPTAVREAAIAALQENQLGYTVALGIP
ELREAIAARYADQFGLTVGLDDVVLTTGSSGGFLLAFLACFDVGDRVAIASPGYPCYRNILTALGCEVVEIPCGADTRFQ
PTAAMLAELDPPVQGVIVASPANPTGTVIAPAELAAIATWCEATGTRLISDEVYHGLVYDGAPPISCAWQTSRKAVVVNS
FSKYYAMTGWRLGWLLVPQELRRAVDRLTGNFTICPPALAQHAAVAAFTPESTAEADGLLAHYAENRRLLLDGLRAIGIS
RLAPADGAFYVYADVSHLTDASLSFCAKLLADTGVAIAPGIDFDTVHGNSFVRLSFAGPTADITEALSRIGGWLR
>Mature_394_residues
SGAHAQRTEPRDVALRAGIPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPTAVREAAIAALQENQLGYTVALGIPE
LREAIAARYADQFGLTVGLDDVVLTTGSSGGFLLAFLACFDVGDRVAIASPGYPCYRNILTALGCEVVEIPCGADTRFQP
TAAMLAELDPPVQGVIVASPANPTGTVIAPAELAAIATWCEATGTRLISDEVYHGLVYDGAPPISCAWQTSRKAVVVNSF
SKYYAMTGWRLGWLLVPQELRRAVDRLTGNFTICPPALAQHAAVAAFTPESTAEADGLLAHYAENRRLLLDGLRAIGISR
LAPADGAFYVYADVSHLTDASLSFCAKLLADTGVAIAPGIDFDTVHGNSFVRLSFAGPTADITEALSRIGGWLR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=408, Percent_Identity=23.5294117647059, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI169881279, Length=408, Percent_Identity=23.5294117647059, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI56713256, Length=329, Percent_Identity=28.5714285714286, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI56713254, Length=329, Percent_Identity=28.5714285714286, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4507369, Length=414, Percent_Identity=23.6714975845411, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI169881281, Length=323, Percent_Identity=21.671826625387, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788722, Length=397, Percent_Identity=27.9596977329975, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=29.1208791208791, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790797, Length=390, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788627, Length=270, Percent_Identity=25.5555555555556, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787710, Length=328, Percent_Identity=27.1341463414634, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=367, Percent_Identity=26.7029972752044, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=323, Percent_Identity=26.9349845201238, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=25, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=326, Percent_Identity=26.3803680981595, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115534666, Length=350, Percent_Identity=25.1428571428571, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=316, Percent_Identity=24.3670886075949, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=24.7448979591837, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=24.7448979591837, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=24.7448979591837, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=24.7448979591837, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI18859735, Length=371, Percent_Identity=24.7978436657682, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41671; Mature: 41540

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAHAQRTEPRDVALRAGIPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPTAVRE
CCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
AAIAALQENQLGYTVALGIPELREAIAARYADQFGLTVGLDDVVLTTGSSGGFLLAFLAC
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHH
FDVGDRVAIASPGYPCYRNILTALGCEVVEIPCGADTRFQPTAAMLAELDPPVQGVIVAS
HCCCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEC
PANPTGTVIAPAELAAIATWCEATGTRLISDEVYHGLVYDGAPPISCAWQTSRKAVVVNS
CCCCCCCEEEHHHHHHHHHHHHHCCCEEECHHHHCCEEECCCCCCEEEECCCCCEEEEEC
FSKYYAMTGWRLGWLLVPQELRRAVDRLTGNFTICPPALAQHAAVAAFTPESTAEADGLL
HHHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEECCHHHHHCCEEEEECCCCCCCHHHHH
AHYAENRRLLLDGLRAIGISRLAPADGAFYVYADVSHLTDASLSFCAKLLADTGVAIAPG
HHHHCCCHHHHHHHHHHCHHHCCCCCCCEEEEEEHHHHCHHHHHHHHHHHHCCCCEEECC
IDFDTVHGNSFVRLSFAGPTADITEALSRIGGWLR
CCCEEECCCCEEEEEECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGAHAQRTEPRDVALRAGIPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPTAVRE
CCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
AAIAALQENQLGYTVALGIPELREAIAARYADQFGLTVGLDDVVLTTGSSGGFLLAFLAC
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHH
FDVGDRVAIASPGYPCYRNILTALGCEVVEIPCGADTRFQPTAAMLAELDPPVQGVIVAS
HCCCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEC
PANPTGTVIAPAELAAIATWCEATGTRLISDEVYHGLVYDGAPPISCAWQTSRKAVVVNS
CCCCCCCEEEHHHHHHHHHHHHHCCCEEECHHHHCCEEECCCCCCEEEECCCCCEEEEEC
FSKYYAMTGWRLGWLLVPQELRRAVDRLTGNFTICPPALAQHAAVAAFTPESTAEADGLL
HHHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEECCHHHHHCCEEEEECCCCCCCHHHHH
AHYAENRRLLLDGLRAIGISRLAPADGAFYVYADVSHLTDASLSFCAKLLADTGVAIAPG
HHHHCCCHHHHHHHHHHCHHHCCCCCCCEEEEEEHHHHCHHHHHHHHHHHHCCCCEEECC
IDFDTVHGNSFVRLSFAGPTADITEALSRIGGWLR
CCCEEECCCCEEEEEECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]