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The map label for this gene is lutB [H]

Identifier: 119870502

GI number: 119870502

Start: 4701449

End: 4702903

Strand: Direct

Name: lutB [H]

Synonym: Mkms_4473

Alternate gene names: 119870502

Gene position: 4701449-4702903 (Clockwise)

Preceding gene: 119870501

Following gene: 119870503

Centisome position: 81.95

GC content: 69.62

Gene sequence:

>1455_bases
GTGAGCACATTCCTCGGCACTCCCGGCACCGGCAACCTGCGCGGAGACGAAGCGTTCCCGCGGGCCGCGCGAAAGGCGTT
GCAGGACAGCCAAATGCGGCGCAACGTCGGACACGCCACCCGCACCATCCGGACCAAACGCCTGCACGCGGTCGGTGAGT
GCGCGGACTGGGAGGAGTTGCGCGCGGCGGGCAGTGCGCTCAAACAGGATGTGCTCGCCCGGCTTCCCGAACTGCTCGAC
GAACTCGAGCGCAACGTCACCGCCCGCGGTGGGGTGGTGCACTGGGCCCGCGACGCCGACGAGGCCAACCGCATCGTGGG
GGAGTTGACCCGGGCCGCCGGGGCCGACGAGGTGGTCAAGGTCAAATCGATGGCCACCCAGGAGATCGGGCTCAACGAGT
ACCTCGAATCCATCGGGATCGCTGCGGTCGAAACCGATCTCGCCGAGCTCATCGTCCAACTCGGACACGACAAGCCGAGC
CACATCCTGGTCCCGGCGATCCATCGCAACCGCGCCGAGATCCGCGAGATCTTCCGGCGTGAGATGCCGGGTACCGCGGA
CCTGACCGATGAGCCCCGTGCCCTCGCCATGGCCGCCCGCGCCCACCTGCGCCGCAAGTTCCTGTCCGCGAAGGTGGCGG
TCAGCGGCGCGAATTTCGGTGTGGCCGAGACGGGTACGCTCGCCGTGGTCGAATCCGAGGGCAACGGCCGGATGTGCCTG
ACGCTGCCGCAGACCCTGATCACCGTCATGGGGATCGAGAAGATCGTGCCGAGGTTCACCGACCTCGAGGTGTTCATGCA
GTTGCTGCCGCGCTCCTCGACCGCCGAGCGGATGAACCCGTACACCTCGATGTGGACCGGCGTGCACCCCGGCGACGGCC
CGCAGGAGTTCCACCTGGTACTGCTCGACAACGGCCGCACCAGCGTGCTCGCCGACGAGGTGGGCCGTGCCGCGCTGCAC
TGCATCCGGTGCAGCGCCTGCCTCAACGTGTGCCCGGTCTACGAGCGCACCGGCGGGCACGCCTACGGATCGGTCTATCC
GGGTCCGATCGGCGCGATCCTGTCCCCGCAGCTGACCGGAACCGCCGGGCACGACGACCCCAACTCCTCCCTGCCGTATG
CCTCGTCGCTGTGCGGCGCCTGCTTCGACGCCTGCCCCGTCCGCATCGACATCCCGTCGATCCTGGTGCATCTGCGGGCG
AAGCAGGTGGATGCCCAGCGCGGCGGCATCCCCGGCGGACAGGATCTGGCCATGAGGGCCGCGGCGTGGGCGATGGCGTC
ACCGCGCCGGTTCGCGCTCGCCGAGAAGGCACTGGCCGCGGGACGATTCGCCGCCAACGCCGACCACCGGATCACTACCC
TGCCGTGGCCGGGGTCGAAGTGGACCGCCAGCCGCGACATGCCCGAACCGCCGACCGAGGCGTTCCGCCAGTGGTGGAGC
CGCACCCATGGCTGA

Upstream 100 bases:

>100_bases
TGCACATCGGGGGTGGGCTGAGCCGCATCCGGTCCGGGGTGCGCACCGTCCACCTCGCCGAGATCCTGGCCTCCACCGAC
GACGCCGTGGCGGGTGCGCG

Downstream 100 bases:

>100_bases
TGCGAAATCGGTTGTCCTGAGCCGGATCAGGGATGCGCTCGCCGCGGCACCGCCGCCGCCGGTGTCCGTTCCGCGCGAGT
ATGACCGGGCACCGCTGGAC

Product: iron-sulfur cluster binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSTFLGTPGTGNLRGDEAFPRAARKALQDSQMRRNVGHATRTIRTKRLHAVGECADWEELRAAGSALKQDVLARLPELLD
ELERNVTARGGVVHWARDADEANRIVGELTRAAGADEVVKVKSMATQEIGLNEYLESIGIAAVETDLAELIVQLGHDKPS
HILVPAIHRNRAEIREIFRREMPGTADLTDEPRALAMAARAHLRRKFLSAKVAVSGANFGVAETGTLAVVESEGNGRMCL
TLPQTLITVMGIEKIVPRFTDLEVFMQLLPRSSTAERMNPYTSMWTGVHPGDGPQEFHLVLLDNGRTSVLADEVGRAALH
CIRCSACLNVCPVYERTGGHAYGSVYPGPIGAILSPQLTGTAGHDDPNSSLPYASSLCGACFDACPVRIDIPSILVHLRA
KQVDAQRGGIPGGQDLAMRAAAWAMASPRRFALAEKALAAGRFAANADHRITTLPWPGSKWTASRDMPEPPTEAFRQWWS
RTHG

Sequences:

>Translated_484_residues
MSTFLGTPGTGNLRGDEAFPRAARKALQDSQMRRNVGHATRTIRTKRLHAVGECADWEELRAAGSALKQDVLARLPELLD
ELERNVTARGGVVHWARDADEANRIVGELTRAAGADEVVKVKSMATQEIGLNEYLESIGIAAVETDLAELIVQLGHDKPS
HILVPAIHRNRAEIREIFRREMPGTADLTDEPRALAMAARAHLRRKFLSAKVAVSGANFGVAETGTLAVVESEGNGRMCL
TLPQTLITVMGIEKIVPRFTDLEVFMQLLPRSSTAERMNPYTSMWTGVHPGDGPQEFHLVLLDNGRTSVLADEVGRAALH
CIRCSACLNVCPVYERTGGHAYGSVYPGPIGAILSPQLTGTAGHDDPNSSLPYASSLCGACFDACPVRIDIPSILVHLRA
KQVDAQRGGIPGGQDLAMRAAAWAMASPRRFALAEKALAAGRFAANADHRITTLPWPGSKWTASRDMPEPPTEAFRQWWS
RTHG
>Mature_483_residues
STFLGTPGTGNLRGDEAFPRAARKALQDSQMRRNVGHATRTIRTKRLHAVGECADWEELRAAGSALKQDVLARLPELLDE
LERNVTARGGVVHWARDADEANRIVGELTRAAGADEVVKVKSMATQEIGLNEYLESIGIAAVETDLAELIVQLGHDKPSH
ILVPAIHRNRAEIREIFRREMPGTADLTDEPRALAMAARAHLRRKFLSAKVAVSGANFGVAETGTLAVVESEGNGRMCLT
LPQTLITVMGIEKIVPRFTDLEVFMQLLPRSSTAERMNPYTSMWTGVHPGDGPQEFHLVLLDNGRTSVLADEVGRAALHC
IRCSACLNVCPVYERTGGHAYGSVYPGPIGAILSPQLTGTAGHDDPNSSLPYASSLCGACFDACPVRIDIPSILVHLRAK
QVDAQRGGIPGGQDLAMRAAAWAMASPRRFALAEKALAAGRFAANADHRITTLPWPGSKWTASRDMPEPPTEAFRQWWSR
THG

Specific function: Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofi

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=469, Percent_Identity=41.36460554371, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 52471; Mature: 52340

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFLGTPGTGNLRGDEAFPRAARKALQDSQMRRNVGHATRTIRTKRLHAVGECADWEEL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RAAGSALKQDVLARLPELLDELERNVTARGGVVHWARDADEANRIVGELTRAAGADEVVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHH
VKSMATQEIGLNEYLESIGIAAVETDLAELIVQLGHDKPSHILVPAIHRNRAEIREIFRR
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHHH
EMPGTADLTDEPRALAMAARAHLRRKFLSAKVAVSGANFGVAETGTLAVVESEGNGRMCL
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCCCEEE
TLPQTLITVMGIEKIVPRFTDLEVFMQLLPRSSTAERMNPYTSMWTGVHPGDGPQEFHLV
ECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCCCHHHHHCCCCCCCCCCEEEEE
LLDNGRTSVLADEVGRAALHCIRCSACLNVCPVYERTGGHAYGSVYPGPIGAILSPQLTG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHCCCCCCC
TAGHDDPNSSLPYASSLCGACFDACPVRIDIPSILVHLRAKQVDAQRGGIPGGQDLAMRA
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AAWAMASPRRFALAEKALAAGRFAANADHRITTLPWPGSKWTASRDMPEPPTEAFRQWWS
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
RTHG
HCCC
>Mature Secondary Structure 
STFLGTPGTGNLRGDEAFPRAARKALQDSQMRRNVGHATRTIRTKRLHAVGECADWEEL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RAAGSALKQDVLARLPELLDELERNVTARGGVVHWARDADEANRIVGELTRAAGADEVVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHH
VKSMATQEIGLNEYLESIGIAAVETDLAELIVQLGHDKPSHILVPAIHRNRAEIREIFRR
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHHH
EMPGTADLTDEPRALAMAARAHLRRKFLSAKVAVSGANFGVAETGTLAVVESEGNGRMCL
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCCCEEE
TLPQTLITVMGIEKIVPRFTDLEVFMQLLPRSSTAERMNPYTSMWTGVHPGDGPQEFHLV
ECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCCCHHHHHCCCCCCCCCCEEEEE
LLDNGRTSVLADEVGRAALHCIRCSACLNVCPVYERTGGHAYGSVYPGPIGAILSPQLTG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHCCCCCCC
TAGHDDPNSSLPYASSLCGACFDACPVRIDIPSILVHLRAKQVDAQRGGIPGGQDLAMRA
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AAWAMASPRRFALAEKALAAGRFAANADHRITTLPWPGSKWTASRDMPEPPTEAFRQWWS
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
RTHG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]