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The map label for this gene is lutA [H]

Identifier: 119870501

GI number: 119870501

Start: 4700697

End: 4701452

Strand: Direct

Name: lutA [H]

Synonym: Mkms_4472

Alternate gene names: 119870501

Gene position: 4700697-4701452 (Clockwise)

Preceding gene: 119870498

Following gene: 119870502

Centisome position: 81.93

GC content: 69.58

Gene sequence:

>756_bases
ATGCGTATCGCCCTGTTCGCGACCTGCCTGGCCGACGCCATGTTCCCGCAGGCGGCCGTCGCCACGGTGCGGCTGCTCGA
ACGGCTCGGCCACGAGGTCGTCTTCCCGGAGAAACAGACCTGTTGCGGTCAGATGCACGTCAACACCGGGTATCTCGACG
AGGCCACGGCGCTGGTGCGCCACCACGTCGACGTGTTCGAACAGGCCGGGTGCGAGGCCGTCGTGGCCCCGTCGGGATCC
TGTGTGGGCTCGGTCCGCCACCAGCACGCGATGGTCGCCCGCCGGGCCGGTGACGAACGGTTGGCCGCCCGCGCGGAGGC
CGTCGCGGCGCGCACCTACGAACTGTCCGAACTGCTGGTCGACGTGCTCGGAGTGCGCGACGTCGGCGCCTACTACCCGC
ACCGGGTCACCTACCACCCCACCTGCCATTCCCTGCGGATGCTGCGGGTGGGTGAGAAACCGTTGGAGCTGCTGCGTCAC
GTGCGGGGGCTGACGTTGGTCGAACTGCCCGACGCCGAGTCCTGCTGCGGTTTCGGGGGGACCTTCGCTCTGAAGAACGC
CGACACCTCGACGGCCATGCTGGCCGACAAGATGGCCCATGTGATCGACTCGGGTGCGGAGATCTGCAGCGCGGGCGATT
CGTCGTGCCTCATGCACATCGGGGGTGGGCTGAGCCGCATCCGGTCCGGGGTGCGCACCGTCCACCTCGCCGAGATCCTG
GCCTCCACCGACGACGCCGTGGCGGGTGCGCGGTGA

Upstream 100 bases:

>100_bases
TCGTGGGCGCGCATGCGATGAGGATAACCATCCACCCTGGTGTGGTCCGACCACATTGACGTACTGTGGTCAGACCACAG
CCCCACGTCCCGGAGCCGTC

Downstream 100 bases:

>100_bases
GCACATTCCTCGGCACTCCCGGCACCGGCAACCTGCGCGGAGACGAAGCGTTCCCGCGGGCCGCGCGAAAGGCGTTGCAG
GACAGCCAAATGCGGCGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MRIALFATCLADAMFPQAAVATVRLLERLGHEVVFPEKQTCCGQMHVNTGYLDEATALVRHHVDVFEQAGCEAVVAPSGS
CVGSVRHQHAMVARRAGDERLAARAEAVAARTYELSELLVDVLGVRDVGAYYPHRVTYHPTCHSLRMLRVGEKPLELLRH
VRGLTLVELPDAESCCGFGGTFALKNADTSTAMLADKMAHVIDSGAEICSAGDSSCLMHIGGGLSRIRSGVRTVHLAEIL
ASTDDAVAGAR

Sequences:

>Translated_251_residues
MRIALFATCLADAMFPQAAVATVRLLERLGHEVVFPEKQTCCGQMHVNTGYLDEATALVRHHVDVFEQAGCEAVVAPSGS
CVGSVRHQHAMVARRAGDERLAARAEAVAARTYELSELLVDVLGVRDVGAYYPHRVTYHPTCHSLRMLRVGEKPLELLRH
VRGLTLVELPDAESCCGFGGTFALKNADTSTAMLADKMAHVIDSGAEICSAGDSSCLMHIGGGLSRIRSGVRTVHLAEIL
ASTDDAVAGAR
>Mature_251_residues
MRIALFATCLADAMFPQAAVATVRLLERLGHEVVFPEKQTCCGQMHVNTGYLDEATALVRHHVDVFEQAGCEAVVAPSGS
CVGSVRHQHAMVARRAGDERLAARAEAVAARTYELSELLVDVLGVRDVGAYYPHRVTYHPTCHSLRMLRVGEKPLELLRH
VRGLTLVELPDAESCCGFGGTFALKNADTSTAMLADKMAHVIDSGAEICSAGDSSCLMHIGGGLSRIRSGVRTVHLAEIL
ASTDDAVAGAR

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=242, Percent_Identity=40.495867768595, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI48994913, Length=247, Percent_Identity=25.9109311740891, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 26847; Mature: 26847

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALFATCLADAMFPQAAVATVRLLERLGHEVVFPEKQTCCGQMHVNTGYLDEATALVR
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEECCCHHHHHCEEECCCCCHHHHHHHHH
HHVDVFEQAGCEAVVAPSGSCVGSVRHQHAMVARRAGDERLAARAEAVAARTYELSELLV
HHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DVLGVRDVGAYYPHRVTYHPTCHSLRMLRVGEKPLELLRHVRGLTLVELPDAESCCGFGG
HHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCHHHCCCCC
TFALKNADTSTAMLADKMAHVIDSGAEICSAGDSSCLMHIGGGLSRIRSGVRTVHLAEIL
CEEECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
ASTDDAVAGAR
HCCCCHHCCCC
>Mature Secondary Structure
MRIALFATCLADAMFPQAAVATVRLLERLGHEVVFPEKQTCCGQMHVNTGYLDEATALVR
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEECCCHHHHHCEEECCCCCHHHHHHHHH
HHVDVFEQAGCEAVVAPSGSCVGSVRHQHAMVARRAGDERLAARAEAVAARTYELSELLV
HHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DVLGVRDVGAYYPHRVTYHPTCHSLRMLRVGEKPLELLRHVRGLTLVELPDAESCCGFGG
HHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCHHHCCCCC
TFALKNADTSTAMLADKMAHVIDSGAEICSAGDSSCLMHIGGGLSRIRSGVRTVHLAEIL
CEEECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
ASTDDAVAGAR
HCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA